The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery von Pendergrass, S.A., Brown-Gentry, K., Dudek, S.M., Torstenson, E.S., Ambite, J.L., Avery, C.L., Buyske, S., Cai, C., Fesinmeyer, M.D., Haiman, C., Heiss, G., Hindorff, L.A., Hsu, C.-N., Jackson, R.D., Kooperberg, C., Le Marchand, L., Lin, Y., Matise, T.C., Moreland, L., Monroe, K., Reiner, A.P., Wallace, R., Wilkens, L.R., Crawford, D.C., Ritchie, M.D.

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Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche von Sarnowski, C, Cousminer, D L, Franceschini, N, Raffield, L M, Jia, G, Fernández-Rhodes, L, Grant, S F A, Hakonarson, H, Lange, L A, Long, J, Sofer, T, Tao, R, Wallace, R B, Wong, Q, Zirpoli, G, Boerwinkle, E, Bradfield, J P, Correa, A, Kooperberg, C L, North, K E, Palmer, J R, Zemel, B S, Zheng, W, Murabito, J M, Lunetta, K L

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Prospective associations of C-reactive protein (CRP) levels and CRP genetic risk scores with risk of total knee and hip replacement for osteoarthritis in a diverse cohort von Shadyab, A.H., Terkeltaub, R., Kooperberg, C., Reiner, A., Eaton, C.B., Jackson, R.D., Krok-Schoen, J.L., Salem, R.M., LaCroix, A.Z.

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Comparison of Self-Report, Hospital Discharge Codes, and Adjudication of Cardiovascular Events in the Women’s Health Initiative von Heckbert, Susan R., Kooperberg, Charles, Safford, Monika M., Psaty, Bruce M., Hsia, Judith, McTiernan, Anne, Gaziano, J. Michael, Frishman, William H., Curb, J. David

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Boosting for detection of gene-environment interactions von Pashova, H., LeBlanc, M., Kooperberg, C.

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Widespread Collaboration of Isw2 and Sin3-Rpd3 Chromatin Remodeling Complexes in Transcriptional Repression von Fazzio, Thomas G., Kooperberg, Charles, Goldmark, Jesse P., Neal, Cassandra, Basom, Ryan, Delrow, Jeffrey, Tsukiyama, Toshio

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Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial von Rossouw, Jacques E, Anderson, Garnet L, Prentice, Ross L, LaCroix, Andrea Z, Kooperberg, Charles, Stefanick, Marcia L, Jackson, Rebecca D, Beresford, Shirley A A, Howard, Barbara V, Johnson, Karen C, Kotchen, Jane Morley, Ockene, Judith

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Statin Use and Incident Frailty in Women Aged 65 Years or Older: Prospective Findings From the Women's Health Initiative Observational Study von LaCroix, Andrea Z., Gray, Shelly L., Aragaki, Aaron, Cochrane, Barbara B., Newman, Anne B., Kooperberg, Charles L., Black, Henry, Curb, J. David, Greenland, Philip, Woods, Nancy F.

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Generalization of adiposity genetic loci to US Hispanic women von Graff, M, Fernández-Rhodes, L, Liu, S, Carlson, C, Wassertheil-Smoller, S, Neuhouser, M, Reiner, A, Kooperberg, C, Rampersaud, E, Manson, J E, Kuller, L H, Howard, B V, Ochs-Balcom, H M, Johnson, K C, Vitolins, M Z, Sucheston, L, Monda, K, North, K E

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Sequence Analysis Using Logic Regression von Kooperberg, Charles, Ruczinski, Ingo, LeBlanc, Michael L., Hsu, Li

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Identifying interacting SNPs using Monte Carlo logic regression von Kooperberg, Charles, Ruczinski, Ingo

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Genetic Landscape of the ACE2 Coronavirus Receptor von Yang, Zhijian, Macdonald-Dunlop, Erin, Chen, Jiantao, Zhai, Ranran, Li, Ting, Richmond, Anne, Klarić, Lucija, Pirastu, Nicola, Ning, Zheng, Zheng, Chenqing, Wang, Yipeng, Huang, Tingting, He, Yazhou, Guo, Huiming, Ying, Kejun, Gustafsson, Stefan, Prins, Bram, Ramisch, Anna, Dermitzakis, Emmanouil T., Png, Grace, Eriksson, Niclas, Haessler, Jeffrey, Hu, Xiaowei, Zanetti, Daniela, Boutin, Thibaud, Hwang, Shih-Jen, Wheeler, Eleanor, Pietzner, Maik, Raffield, Laura M., Kalnapenkis, Anette, Peters, James E., Viñuela, Ana, Gilly, Arthur, Elmståhl, Sölve, Dedoussis, George, Petrie, John R., Polašek, Ozren, Folkersen, Lasse, Chen, Yan, Yao, Chen, Võsa, Urmo, Pairo-Castineira, Erola, Clohisey, Sara, Bretherick, Andrew D., Rawlik, Konrad, Esko, Tõnu, Enroth, Stefan, Johansson, Åsa, Gyllensten, Ulf, Langenberg, Claudia, Levy, Daniel, Hayward, Caroline, Assimes, Themistocles L., Kooperberg, Charles, Manichaikul, Ani W., Siegbahn, Agneta, Wallentin, Lars, Lind, Lars, Zeggini, Eleftheria, Schwenk, Jochen M., Butterworth, Adam S., Michaëlsson, Karl, Pawitan, Yudi, Joshi, Peter K., Baillie, J. Kenneth, Mälarstig, Anders, Reiner, Alexander P., Wilson, James F., Shen, Xia

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Variation in 24 hemostatic genes and associations with non‐fatal myocardial infarction and ischemic stroke von SMITH, N. L., BIS, J. C., BIAGIOTTI, S., RICE, K., LUMLEY, T., KOOPERBERG, C., WIGGINS, K. L., HECKBERT, S. R., PSATY, B. M.

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Two-stage testing procedures with independent filtering for genome-wide gene-environment interaction von DAI, JAMES Y., KOOPERBERG, CHARLES, LEBLANC, MICHAEL, PRENTICE, ROSS L.

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The age-dependent association of risk factors with pancreatic cancer von Yuan, C., Kim, J., Wang, Q.L., Lee, A.A., Babic, A., Amundadottir, L.T., Ardanaz, E., Arslan, A.A., Beane-Freeman, L.E., Bracci, P.M., Bueno-de-Mesquita, B., Du, M., Gallinger, S., Giles, G.G., Goodman, P.J., Katzke, V.A., Klein, A.P., Kooperberg, C., Kraft, P., Li, D., Malats, N., Marchand, L.L., McCullough, M.L., Milne, R.L., Neoptolemos, J.P., Perdomo, S., Petersen, G.M., Risch, H.A., Shu, X.O., Stolzenberg-Solomon, R.Z., Van Den Eeden, S.K., Visvanathan, K., White, E., Wolpin, B.M., Zheng, W., Amundadottir, L.T., Klein, A.P., Li, D., McCullough, M.L., Petersen, G.M., Risch, H.A., Stolzenberg-Solomon, R.Z., Perez, K., Ng, K., Giovannucci, E.L., Stampfer, M.J., Kraft, P., Wolpin, B.M.

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Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia von Stitziel, Nathan O, Fouchier, Sigrid W, Sjouke, Barbara, Peloso, Gina M, Moscoso, Alessa M, Auer, Paul L, Goel, Anuj, Gigante, Bruna, Barnes, Timothy A, Melander, Olle, Orho-Melander, Marju, Duga, Stefano, Sivapalaratnam, Suthesh, Nikpay, Majid, Martinelli, Nicola, Girelli, Domenico, Jackson, Rebecca D, Kooperberg, Charles, Lange, Leslie A, Ardissino, Diego, McPherson, Ruth, Farrall, Martin, Watkins, Hugh, Reilly, Muredach P, Rader, Daniel J, de Faire, Ulf, Schunkert, Heribert, Erdmann, Jeanette, Samani, Nilesh J, Charnas, Lawrence, Altshuler, David, Gabriel, Stacey, Kastelein, John J.P, Defesche, Joep C, Nederveen, Aart J, Kathiresan, Sekar, Hovingh, G Kees

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The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote von Schübeler, Dirk, MacAlpine, David M, Scalzo, David, Wirbelauer, Christiane, Kooperberg, Charles, van Leeuwen, Fred, Gottschling, Daniel E, O'Neill, Laura P, Turner, Bryan M, Delrow, Jeffrey, Bell, Stephen P, Groudine, Mark

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Recreational Physical Activity and the Risk of Breast Cancer in Postmenopausal Women: The Women's Health Initiative Cohort Study von McTiernan, Anne, Kooperberg, Charles, White, Emily, Wilcox, Sara, Coates, Ralph, Adams-Campbell, Lucile L, Woods, Nancy, Ockene, Judith

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Electrocardiographic abnormalities that predict coronary heart disease events and mortality in postmenopausal women : The women's health initiative von RAUTAHARJU, Pentti M, KOOPERBERG, Charles, LARSON, Joseph C, LACROIX, Andrea

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Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps von Iotchkova, Valentina, Huang, Jie, Morris, John A, Jain, Deepti, Barbieri, Caterina, Walter, Klaudia, Min, Josine L, Chen, Lu, Astle, William, Cocca, Massimilian, Deelen, Patrick, Elding, Heather, Farmaki, Aliki-Eleni, Franklin, Christopher S, Franberg, Mattias, Gaunt, Tom R, Hofman, Albert, Jiang, Tao, Kleber, Marcus E, Lachance, Genevieve, Luan, Jian'an, Malerba, Giovanni, Matchan, Angela, Mead, Daniel, Memari, Yasin, Ntalla, Ioanna, Panoutsopoulou, Kalliope, Pazoki, Raha, Perry, John R B, Rivadeneira, Fernando, Sabater-Lleal, Maria, Sennblad, Bengt, Shin, So-Youn, Southam, Lorraine, Traglia, Michela, van Dijk, Freerk, van Leeuwen, Elisabeth M, Zaza, Gianluigi, Zhang, Weihua, Amin, Najaf, Butterworth, Adam, Chambers, John C, Dedoussis, George, Dehghan, Abbas, Franco, Oscar H, Franke, Lude, Frontini, Mattia, Gambaro, Giovanni, Gasparini, Paolo, Hamsten, Anders, Issacs, Aaron, Kooner, Jaspal S, Kooperberg, Charles, Langenberg, Claudia, Marz, Winfried, Scott, Robert A, Swertz, Morris A, Toniolo, Daniela, Uitterlinden, Andre G, van Duijn, Cornelia M, Watkins, Hugh, Zeggini, Eleftheria, Maurano, Mathew T, Timpson, Nicholas J, Reiner, Alexander P, Auer, Paul L, Soranzo, Nicole

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