Pemetrexed exposure predicts toxicity in advanced non–small-cell lung cancer: A prospective cohort study von Visser, S., Koolen, S.L.W., de Bruijn, P., Belderbos, H.N.A., Cornelissen, R., Mathijssen, R.H.J., Stricker, B.H., Aerts, J.G.J.V.

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Intravenous-to-Oral Switch in Anticancer Chemotherapy: A Focus on Docetaxel and Paclitaxel von Koolen, S L W, Beijnen, J H, Schellens, J H M

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Therapeutic drug monitoring-based precision dosing of oral targeted therapies in oncology: a prospective multicenter study von Groenland, S.L., van Eerden, R.A.G., Westerdijk, K., Meertens, M., Koolen, S.L.W., Moes, D.J.A.R., de Vries, N., Rosing, H., Otten, H., Vulink, A.J.E., Desar, I.M.E., Imholz, A.L.T., Gelderblom, H., van Erp, N.P., Beijnen, J.H., Mathijssen, R.H.J., Huitema, A.D.R., Steeghs, N.

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Pharmaceutical development and preliminary clinical testing of an oral solid dispersion formulation of docetaxel (ModraDoc001) von Moes, J.J., Koolen, S.L.W., Huitema, A.D.R., Schellens, J.H.M., Beijnen, J.H., Nuijen, B.

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A new method for the determination of total and released docetaxel from docetaxel-entrapped core-crosslinked polymeric micelles (CriPec®) by LC–MS/MS and its clinical application i... von Braal, C.L., de Bruijn, P., Atrafi, F., van Geijn, M., Rijcken, C.J.F., Mathijssen, R.H.J., Koolen, S.L.W.

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Clinical implications of nintedanib pharmacokinetics in patients with pulmonary fibrosis von Agema, B.C., Berrich, M., Seuren, L., Sassen, S.D.T., Miedema, J.R., Koch, B.C.P., Wijsenbeek, M.S., Koolen, S.L.W., Mathijssen, R.H.J., Veerman, G.D.M.

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From Mouse to Man: Predictions of Human Pharmacokinetics of Orally Administered Docetaxel From Preclinical Studies von Koolen, S. L. W., van Waterschoot, R. A. B., van Tellingen, O., Schinkel, A. H., Beijnen, J. H., Schellens, J. H. M., Huitema, A. D. R.

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The impact of endoxifen-guided tamoxifen dose reductions on endocrine side-effects in patients with primary breast cancer von Buijs, S.M., Hoop, E. Oomen-de, Braal, C.L., van Rosmalen, M.M., Drooger, J.C., van Rossum-Schornagel, Q.C., Vastbinder, M.B., Koolen, S.L.W., Jager, A., Mathijssen, R.H.J.

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Sunitinib for the treatment of metastatic gastrointestinal stromal tumors: the effect of TDM-guided dose optimization on clinical outcomes von Giraud, E.L., Westerdijk, K., van der Kleij, M.B.A., Guchelaar, N.A.D., Meertens, M., Bleckman, R.F., Rieborn, A., Mohammadi, M., Roets, E., Mathijssen, R.H.J., Huitema, A.D.R., Koolen, S.L.W., Gelderblom, H., Moes, D.J.A.R., Reyners, A.K.L., Touw, D.J., Keizer-Heldens, P., Oosten, A.W., van der Graaf, W.T.A., Steeghs, N., van Erp, N.P., Desar, I.M.E.

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Imatinib, sunitinib and pazopanib: From flat‐fixed dosing towards a pharmacokinetically guided personalized dose von Westerdijk, Kim, Desar, Ingrid M.E., Steeghs, Neeltje, Graaf, Winette T.A., Erp, Nielka P.

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P10.24.B SCREENING NON-ONCOLOGICAL DRUGS IN A PATIENT-DERIVED GLIOBLASTOMA MODEL IDENTIFIES PITAVASTATIN WITH POTENTIAL ANTITUMOR ACTIVITY von Zekanovic, S, Achaiber Sing, P, Basuki, A, Koolen, S L W, Ntafoulis, I, den Hollander, C W J, Chien, M P, Li, Y, Mustafa, D A M, Dirven, C M F, Leenstra, S, Lamfers, M L M

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P10.28.B INTERMODEL VARIATION OF BBB PERMEABILITY AFFECTS CNS DRUG DELIVERY IN PDX MODELS OF GBM von Ntafoulis, I, Koolen, S L W, den Hollander, C W J, Goedknegt, E, Haeck, J, Kers, T V, Dijkhuizen, S, van Dis, V, van den Bosch, T P P, Gao, Z, Mezzanotte, L, van Tellingen, O, Dirven, C M F, Leenstra, S, Lamfers, M L M

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Prevention of VEGF inhibitor-induced toxicity by salt restriction: the SUN-SALT study von Van Doorn, L, Visser, W J, Van Dorst, D C H, Mirabito Colafella, K M M, Koolen, S L W, Van Egmond-De Mik, A M E, Oomen-De Hoop, E, Bins, S, Hoorn, E J, Danser, A H, Mathijssen, A H, Versmissen, J

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Recent Clinical Developments of Nanomediated Drug Delivery Systems of Taxanes for the Treatment of Cancer von van Eerden, Ruben A G, Mathijssen, Ron H J, Koolen, Stijn L W

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Inhibiting CDK4/6 in Breast Cancer with Palbociclib, Ribociclib, and Abemaciclib: Similarities and Differences von Braal, C. Louwrens, Jongbloed, Elisabeth M., Wilting, Saskia M., Mathijssen, Ron H. J., Koolen, Stijn L. W., Jager, Agnes

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A review of factors explaining variability in fentanyl pharmacokinetics; focus on implications for cancer patients von Kuip, Evelien J. M., Zandvliet, Maarten L., Koolen, Stijn L. W., Mathijssen, Ron H. J., Rijt, Carin C. D.

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Overt Thyroid Dysfunction and Anti-Thyroid Antibodies Predict Response to Anti-PD-1 Immunotherapy in Cancer Patients von Basak, Edwin A, van der Meer, Jan W M, Hurkmans, Daan P, Schreurs, Marco W J, Oomen-de Hoop, Esther, van der Veldt, Astrid A M, Bins, Sander, Joosse, Arjen, Koolen, Stijn L W, Debets, Reno, Peeters, Robin P, Aerts, Joachim G J V, Mathijssen, Ron H J, Medici, Marco

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Effects of smoking and body mass index on the exposure of fentanyl in patients with cancer von Kuip, Evelien J M, Oldenmenger, Wendy H, Thijs-Visser, Martine F, de Bruijn, Peter, Oosten, Astrid W, Oomen-de Hoop, Esther, Koolen, Stijn L W, Van der Rijt, Carin C D, Mathijssen, Ron H J

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Quantification of afatinib, alectinib, crizotinib and osimertinib in human plasma by liquid chromatography/triple-quadrupole mass spectrometry; focusing on the stability of osimert... von Veerman, G.D. Marijn, Lam, Mei H., Mathijssen, Ron H.J., Koolen, Stijn L.W., de Bruijn, Peter

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UGT1A1 genotype-guided dosing of irinotecan: A prospective safety and cost analysis in poor metaboliser patients von Hulshof, Emma C., de With, Mirjam, de Man, Femke M., Creemers, Geert-Jan, Deiman, Birgit A.L.M., Swen, Jesse J., Houterman, Saskia, Koolen, Stijn L.W., Bins, Sander, Thijs, Anna M.J., Laven, Marjan M.J., Hövels, Anke M., Luelmo, Saskia A.C., Houtsma, Danny, Shulman, Katerina, McLeod, Howard L., van Schaik, Ron H.N., Guchelaar, Henk-Jan, Mathijssen, Ron H.J., Gelderblom, Hans, Deenen, Maarten J.

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