The Multifunctional Protein BAG3 von Myers, Valerie D., MS, McClung, Joseph M., PhD, Wang, JuFang, MD, Tahrir, Farzaneh G., PhD, Gupta, Manish K., PhD, Gordon, Jennifer, PhD, Kontos, Christopher H., MD, Khalili, Kamel, PhD, Cheung, Joseph Y., MD, PhD, Feldman, Arthur M., MD, PhD

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The Multifunctional Protein BAG3: A Novel Therapeutic Target in Cardiovascular Disease von Myers, Valerie D, McClung, Joseph M, Wang, JuFang, Tahrir, Farzaneh G, Gupta, Manish K, Gordon, Jennifer, Kontos, Christopher H, Khalili, Kamel, Cheung, Joseph Y, Feldman, Arthur M

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Central Illustration: The Pleiotropic Effects of BAG3 von Myers, Valerie D., McClung, Joseph M., JuFang Wang, Tahrir, Farzaneh G., Gupta, Manish K., Gordon, Jennifer, Kontos, Christopher H., Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M.

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Figure 1: The Structure of BAG3 and its Protein-Binding Domains von Myers, Valerie D., McClung, Joseph M., JuFang Wang, Tahrir, Farzaneh G., Gupta, Manish K., Gordon, Jennifer, Kontos, Christopher H., Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M.

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Figure 2: Molecular Pathology of BAG3-Mediated Autophagy During Hypoxia-Reoxygenation von Myers, Valerie D., McClung, Joseph M., JuFang Wang, Tahrir, Farzaneh G., Gupta, Manish K., Gordon, Jennifer, Kontos, Christopher H., Khalili, Kamel, Cheung, Joseph Y., Feldman, Arthur M.

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A comprehensive, targeted approach to the clinical care of athletes following sport-related concussion von Collins, Michael W., Kontos, Anthony P., Reynolds, Erin, Murawski, Christopher D., Fu, Freddie H.

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BAG3 (Bcl-2–Associated Athanogene-3) Coding Variant in Mice Determines Susceptibility to Ischemic Limb Muscle Myopathy by Directing Autophagy von McClung, Joseph M, McCord, Timothy J, Ryan, Terence E, Schmidt, Cameron A, Green, Tom D, Southerland, Kevin W, Reinardy, Jessica L, Mueller, Sarah B, Venkatraman, Talaignair N, Lascola, Christopher D, Keum, Sehoon, Marchuk, Douglas A, Spangenburg, Espen E, Dokun, Ayotunde, Annex, Brian H, Kontos, Christopher D

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Endothelial Regulation of Microvascular Growth and Stability by Ang‐Tie and VEGF Signaling Pathways: A Mechanistic Computational Systems Biology Model von Zhang, Yu, Kontos, Christopher D., Annex, Brian H., Popel, Aleksander S.

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Interleukin-1 Blockade With Anakinra to Prevent Adverse Cardiac Remodeling After Acute Myocardial Infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] P... von Abbate, Antonio, MD, PhD, Kontos, Michael C., MD, Grizzard, John D., MD, Biondi-Zoccai, Giuseppe G.L., MD, Van Tassell, Benjamin W., PharmD, Robati, Roshanak, MD, Roach, Lenore M., RN, Arena, Ross A., PhD, Roberts, Charlotte S., ACNP, Varma, Amit, MD, Gelwix, Christopher C., MD, Salloum, Fadi N., PhD, Hastillo, Andrea, MD, Dinarello, Charles A., MD, Vetrovec, George W., MD

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PTEN Modulates Vascular Endothelial Growth Factor-Mediated Signaling and Angiogenic Effects von Huang, Jianhua, Kontos, Christopher D.

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Angiopoietin-Tie Signaling Pathway in Endothelial Cells: A Computational Model von Zhang, Yu, Kontos, Christopher D., Annex, Brian H., Popel, Aleksander S.

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Skeletal Muscle–Specific Genetic Determinants Contribute to the Differential Strain-Dependent Effects of Hindlimb Ischemia in Mice von McClung, Joseph M, McCord, Timothy J, Keum, Sehoon, Johnson, Soraya, Annex, Brian H, Marchuk, Douglas A, Kontos, Christopher D

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Negative Regulation of Myofibroblast Differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10) von White, Eric S, Atrasz, Rachelle G, Hu, Biao, Phan, Sem H, Stambolic, Vuk, Mak, Tak W, Hogaboam, Cory M, Flaherty, Kevin R, Martinez, Fernando J, Kontos, Christopher D, Toews, Galen B

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p53 functions in endothelial cells to prevent radiation-induced myocardial injury in mice von Lee, Chang-Lung, Moding, Everett J, Cuneo, Kyle C, Li, Yifan, Sullivan, Julie M, Mao, Lan, Washington, Iman, Jeffords, Laura B, Rodrigues, Rafaela C, Ma, Yan, Das, Shiva, Kontos, Christopher D, Kim, Yongbaek, Rockman, Howard A, Kirsch, David G

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Coupled myovascular expansion directs cardiac growth and regeneration von DeBenedittis, Paige, Karpurapu, Anish, Henry, Albert, Thomas, Michael C., McCord, Timothy J., Brezitski, Kyla, Prasad, Anil, Baker, Caroline E., Kobayashi, Yoshihiko, Shah, Svati H., Kontos, Christopher D., Tata, Purushothama Rao, Lumbers, R. Thomas, Karra, Ravi

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A National Study on the Effects of Concussion in Collegiate Athletes and US Military Service Academy Members: The NCAA–DoD Concussion Assessment, Research and Education (CARE) Cons... von Broglio, Steven P., McCrea, Michael, McAllister, Thomas, Harezlak, Jaroslaw, Katz, Barry, Hack, Dallas, Hainline, Brian

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PTEN as an Effector in the Signaling of Antimigratory G Protein-Coupled Receptor von Sanchez, Teresa, Thangada, Shobha, Wu, Ming-Tao, Kontos, Christopher D., Wu, Dianqing, Wu, Hong, Hla, Timothy, Exton, John H.

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Guidelines for reasonable and appropriate care in the emergency department (GRACE): Recurrent, low‐risk chest pain in the emergency department von Musey, Paul I., Bellolio, Fernanda, Upadhye, Suneel, Chang, Anna Marie, Diercks, Deborah B., Gottlieb, Michael, Hess, Erik P., Kontos, Michael C., Mumma, Bryn E., Probst, Marc A., Stahl, John H., Stopyra, Jason P., Kline, Jeffrey A., Carpenter, Christopher R.

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In Mice With Type 2 Diabetes, a Vascular Endothelial Growth Factor (VEGF)-Activating Transcription Factor Modulates VEGF Signaling and Induces Therapeutic Angiogenesis After Hindli... von Li, Yongjun, Hazarika, Surovi, Xie, Donghua, Pippen, Anne M, Kontos, Christopher D, Annex, Brian H

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Hip thrust and back squat training elicit similar gluteus muscle hypertrophy and transfer similarly to the deadlift von Plotkin, Daniel L, Rodas, Merlina A, Vigotsky, Andrew D, McIntosh, Mason C, Breeze, Emma, Ubrik, Rachel, Robitzsch, Cole, Agyin-Birikorang, Anthony, Mattingly, Madison L, Michel, J Max, Kontos, Nicholas J, Lennon, Sarah, Frugé, Andrew D, Wilburn, Christopher M, Weimar, Wendi H, Bashir, Adil, Beyers, Ronald J, Henselmans, Menno, Contreras, Bret M, Roberts, Michael D

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