The Eph-Receptor A7 Is a Soluble Tumor Suppressor for Follicular Lymphoma von Oricchio, Elisa, Nanjangud, Gouri, Wolfe, Andrew L., Schatz, Jonathan H., Mavrakis, Konstantinos J., Jiang, Man, Liu, Xiaoping, Bruno, Joanne, Heguy, Adriana, Olshen, Adam B., Socci, Nicholas D., Teruya-Feldstein, Julie, Weis-Garcia, Frances, Tam, Wayne, Shaknovich, Rita, Melnick, Ari, Himanen, Juha P., Chaganti, R.S.K., Wendel, Hans-Guido

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Forward genetic screens in mice uncover mediators and suppressors of metastatic reactivation von Gao, Hua, Chakraborty, Goutam, Lee-Lim, Ai Ping, Mavrakis, Konstantinos J., Wendel, Hans-Guido, Giancotti, Filippo G.

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Tumorigenic activity and therapeutic inhibition of Rheb GTPase von Mavrakis, Konstantinos J, Zhu, Hong, Silva, Ricardo L A, Mills, John R, Teruya-Feldstein, Julie, Lowe, Scott W, Tam, Wayne, Pelletier, Jerry, Wendel, Hans-Guido

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Cooperative control of tumor suppressor genes by a network of oncogenic microRNAs von Mavrakis, Konstantinos J., Leslie, Christina S., Wendel, Hans-Guido

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RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer von Wolfe, Andrew L., Singh, Kamini, Zhong, Yi, Drewe, Philipp, Rajasekhar, Vinagolu K., Sanghvi, Viraj R., Mavrakis, Konstantinos J., Jiang, Man, Roderick, Justine E., Van der Meulen, Joni, Schatz, Jonathan H., Rodrigo, Christina M., Zhao, Chunying, Rondou, Pieter, de Stanchina, Elisa, Teruya-Feldstein, Julie, Kelliher, Michelle A., Speleman, Frank, Porco, John A., Pelletier, Jerry, Rätsch, Gunnar, Wendel, Hans-Guido

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Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover von Mavrakis, Konstantinos J, Andrew, Rebecca L, Lee, Kian Leong, Petropoulou, Chariklia, Dixon, James E, Navaratnam, Naveenan, Norris, Dominic P, Episkopou, Vasso

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Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5 von Mavrakis, Konstantinos J., McDonald, E. Robert, Schlabach, Michael R., Billy, Eric, Hoffman, Gregory R., deWeck, Antoine, Ruddy, David A., Venkatesan, Kavitha, Yu, Jianjun, McAllister, Gregg, Stump, Mark, deBeaumont, Rosalie, Ho, Samuel, Yue, Yingzi, Liu, Yue, Yan-Neale, Yan, Yang, Guizhi, Lin, Fallon, Yin, Hong, Gao, Hui, Kipp, D. Randal, Zhao, Songping, McNamara, Joshua T., Sprague, Elizabeth R., Zheng, Bing, Lin, Ying, Cho, Young Shin, Gu, Justin, Crawford, Kenneth, Ciccone, David, Vitari, Alberto C., Lai, Albert, Capka, Vladimir, Hurov, Kristen, Porter, Jeffery A., Tallarico, John, Mickanin, Craig, Lees, Emma, Pagliarini, Raymond, Keen, Nicholas, Schmelzle, Tobias, Hofmann, Francesco, Stegmeier, Frank, Sellers, William R.

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Graded Smad2/3 activation is converted directly into levels of target gene expression in embryonic stem cells von Guzman-Ayala, Marcela, Lee, Kian Leong, Mavrakis, Konstantinos J, Goggolidou, Paraskevi, Norris, Dominic P, Episkopou, Vasso

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A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL) von Wendel, Hans-Guido, Mavrakis, Konstantinos J, Van Der Meulen, Joni, Wolfe, Andrew L, Liu, Xiaoping, Mets, Evelien, Taghon, Tom, Khan, Aly A, Setty, Manu, Rondou, Pieter, Vandenberghe, Peter, Delabesse, Eric, Benoit, Yves, Socci, Nicholas B, Leslie, Christina S, Van Vlierberghe, Pieter, Speleman, Frank

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TargetScreen: An unbiased approach to identify functionally important microRNA targets von Mavrakis, Konstantinos J., Wendel, Hans-Guido

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Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia von Wendel, Hans-Guido, Zuber, Johannes, Leslie, Christina S, McJunkin, Katherine, Paddison, Patrick J, Ferrando, Adolfo, Khan, Aly A, Tam, Wayne, Parker, Joel S, Wolfe, Andrew L, de Keersmaecker, Kim, Mavrakis, Konstantinos J, Palomero, Teresa, James, Taneisha, Oricchio, Elisa

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Translational control and cancer therapy von Mavrakis, Konstantinos J., Wendel, Hans-Guido

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Arkadia Induces Degradation of SnoN and c-Ski to Enhance Transforming Growth Factor-β Signaling von Nagano, Yoshiko, Mavrakis, Konstantinos J., Lee, Kian Leong, Fujii, Tomoko, Koinuma, Daizo, Sase, Hitoshi, Yuki, Keiko, Isogaya, Kazunobu, Saitoh, Masao, Imamura, Takeshi, Episkopou, Vasso, Miyazono, Kohei, Miyazawa, Keiji

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Cell-selective labeling using amino acid precursors for proteomic studies of multicellular environments von Gauthier, Nicholas P, Soufi, Boumediene, Walkowicz, William E, Pedicord, Virginia A, Mavrakis, Konstantinos J, Macek, Boris, Gin, David Y, Sander, Chris, Miller, Martin L

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Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia von Sanghvi, Viraj R, Mavrakis, Konstantinos J, Van der Meulen, Joni, Boice, Michael, Wolfe, Andrew L, Carty, Mark, Mohan, Prathibha, Rondou, Pieter, Socci, Nicholas D, Benoit, Yves, Taghon, Tom, Van Vlierberghe, Pieter, Leslie, Christina S, Speleman, Frank, Wendel, Hans-Guido

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Assessment of spatial transcriptomics for oncology discovery von Lyubetskaya, Anna, Rabe, Brian, Fisher, Andrew, Lewin, Anne, Neuhaus, Isaac, Brett, Constance, Brett, Todd, Pereira, Ethel, Golhar, Ryan, Kebede, Sami, Font-Tello, Alba, Mosure, Kathy, Van Wittenberghe, Nicholas, Mavrakis, Konstantinos J., MacIsaac, Kenzie, Chen, Benjamin J., Drokhlyansky, Eugene

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Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening von McDonald, E. Robert, de Weck, Antoine, Schlabach, Michael R., Billy, Eric, Mavrakis, Konstantinos J., Hoffman, Gregory R., Belur, Dhiren, Castelletti, Deborah, Frias, Elizabeth, Gampa, Kalyani, Golji, Javad, Kao, Iris, Li, Li, Megel, Philippe, Perkins, Thomas A., Ramadan, Nadire, Ruddy, David A., Silver, Serena J., Sovath, Sosathya, Stump, Mark, Weber, Odile, Widmer, Roland, Yu, Jianjun, Yu, Kristine, Yue, Yingzi, Abramowski, Dorothee, Ackley, Elizabeth, Barrett, Rosemary, Berger, Joel, Bernard, Julie L., Billig, Rebecca, Brachmann, Saskia M., Buxton, Frank, Caothien, Roger, Caushi, Justina X., Chung, Franklin S., Cortés-Cros, Marta, deBeaumont, Rosalie S., Delaunay, Clara, Desplat, Aurore, Duong, William, Dwoske, Donald A., Eldridge, Richard S., Farsidjani, Ali, Feng, Fei, Feng, JiaJia, Flemming, Daisy, Forrester, William, Galli, Giorgio G., Gao, Zhenhai, Gauter, François, Gibaja, Veronica, Haas, Kristy, Hattenberger, Marc, Hood, Tami, Hurov, Kristen E., Jagani, Zainab, Jenal, Mathias, Johnson, Jennifer A., Jones, Michael D., Kapoor, Avnish, Korn, Joshua, Liu, Jilin, Liu, Qiumei, Liu, Shumei, Liu, Yue, Loo, Alice T., Macchi, Kaitlin J., Martin, Typhaine, McAllister, Gregory, Meyer, Amandine, Mollé, Sandra, Pagliarini, Raymond A., Phadke, Tanushree, Repko, Brian, Schouwey, Tanja, Shanahan, Frances, Shen, Qiong, Stamm, Christelle, Stephan, Christine, Stucke, Volker M., Tiedt, Ralph, Varadarajan, Malini, Venkatesan, Kavitha, Vitari, Alberto C., Wallroth, Marco, Weiler, Jan, Zhang, Jing, Mickanin, Craig, Myer, Vic E., Porter, Jeffery A., Lai, Albert, Bitter, Hans, Lees, Emma, Keen, Nicholas, Kauffmann, Audrey, Stegmeier, Frank, Hofmann, Francesco, Schmelzle, Tobias, Sellers, William R.

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Mouse models of cancer as biological filters for complex genomic data von Oricchio, Elisa, Wolfe, Andrew L, Schatz, Jonathan H, Mavrakis, Konstantinos J, Wendel, Hans-Guido

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RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer von Wolfe, Andrew L, Singh, Kamini, Zhong, Yi, Drewe, Philipp, Rajasekhar, Vinagolu K, Sanghvi, Viraj R, Mavrakis, Konstantinos J, Jiang, Man, Roderick, Justine E, Van der Meulen, Joni, Schatz, Jonathan H, Rodrigo, Christina M, Zhao, Chunying, Rondou, Pieter, de Stanchina, Elisa, Teruya-Feldstein, Julie, Kelliher, Michelle A, Speleman, Frank, Porco, Jr., John A, Pelletier, Jerry, Ratsch, Gunnar, Wendel, Hans-Guido

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DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA von Mavrakis, Konstantinos J, McKinlay, Karen J, Jones, Peter, Sablitzky, Fred

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