Nrf2 promotes survival following exposure to ionizing radiation von Sekhar, Konjeti R., Freeman, Michael L.

Volltext

Radiosensitization by enzalutamide for human prostate cancer is mediated through the DNA damage repair pathway von Sekhar, Konjeti R, Wang, Jian, Freeman, Michael L, Kirschner, Austin N

Volltext

Glutathione peroxidase 4 inhibition induces ferroptosis and mTOR pathway suppression in thyroid cancer von Sekhar, Konjeti R., Hanna, David N., Cyr, Sriram, Baechle, Jordan J., Kuravi, Sudhakiranmayi, Balusu, Ramesh, Rathmell, Kimryn, Baregamian, Naira

Volltext

The Role of Nrf2 in the Response to Normal Tissue Radiation Injury von Cameron, Brent D, Sekhar, Konjeti R, Ofori, Maxwell, Freeman, Michael L

Volltext

Cysteine-based regulation of the CUL3 adaptor protein Keap1 von Sekhar, Konjeti R., Rachakonda, Girish, Freeman, Michael L.

Volltext

Engineering functional 3-dimensional patient-derived endocrine organoids for broad multiplatform applications von Baregamian, Naira, Sekhar, Konjeti R., Krystofiak, Evan S., Vinogradova, Maria, Thomas, Giju, Mannoh, Emmanuel, Solórzano, Carmen C., Kiernan, Colleen M., Mahadevan-Jansen, Anita, Abumrad, Naji, Freeman, Michael L., Weiss, Vivian L., Rathmell, Jeffrey C., Rathmell, W. Kimryn

Volltext

Specific Patterns of Electrophile Adduction Trigger Keap1 Ubiquitination and Nrf2 Activation von Hong, Fei, Sekhar, Konjeti R., Freeman, Michael L., Liebler, Daniel C.

Volltext

Loss of Nrf2 promotes alveolar type 2 cell loss in irradiated, fibrotic lung von Traver, Geri, Mont, Stacey, Gius, David, Lawson, William E., Ding, George X., Sekhar, Konjeti R., Freeman, Michael L.

Volltext

Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells von CAO, Carolyn, SUBHAWONG, Ty, ALBERT, Jeffrey M, KWANG WOON KIM, LING GENG, SEKHAR, Konjeti R, YOUNG JIN GI, BO LU

Volltext

Covalent Modification at Cys151 Dissociates the Electrophile Sensor Keap1 from the Ubiquitin Ligase CUL3 von Rachakonda, Girish, Xiong, Ying, Sekhar, Konjeti R, Stamer, Sheryl L, Liebler, Daniel C, Freeman, Michael L

Volltext

Ferroptosis Inducers in Thyroid Cancer von Sekhar, Konjeti R., Cyr, Sriram, Baregamian, Naira

Volltext

Metabolism of parathyroid organoids von Sekhar, Konjeti R, Codreanu, Simona G, Williams, Olivia C, Rathmell, Jeffrey C, Rathmell, W Kimryn, McLean, John A, Sherrod, Stacy D, Baregamian, Naira

Volltext

Novel n-3 Fatty Acid Oxidation Products Activate Nrf2 by Destabilizing the Association between Keap1 and Cullin3 von Gao, Ling, Wang, Jiakun, Sekhar, Konjeti R., Yin, Huiyong, Yared, Nicholas F., Schneider, Scott N., Sasi, Soumya, Dalton, Timothy P., Anderson, Mark E., Chan, Jefferson Y., Morrow, Jason D., Freeman, Michael L.

Volltext

Nucleophosmin Plays a Role in Repairing DNA Damage and Is a Target for Cancer Treatment von Sekhar, Konjeti R, Freeman, Michael L

Volltext

Activating Transcription Factor 3 Is a Novel Repressor of the Nuclear Factor Erythroid-Derived 2-Related Factor 2 (Nrf2)-Regulated Stress Pathway von BROWN, Stephan L, SEKHAR, Konjeti R, RACHAKONDA, Girish, SASI, Soumya, FREEMAN, Michael L

Volltext

Xanthine Analogs Suppress Trypanosoma cruzi Infection In Vitro Using PDEs as Targets von Banga, Amita R., Sekhar, Konjeti R., Rayford, Kayla J., Arun, Ashutosh, Odiase, Peace, Garg, Amar P., Lima, Maria F., Nde, Pius N., Villalta, Fernando, Rachakonda, Girish

Volltext

Targeting Nucleophosmin 1 Represents a Rational Strategy for Radiation Sensitization von Sekhar, Konjeti R., PhD, Benamar, Mouadh, BS, Venkateswaran, Amudhan, PhD, Sasi, Soumya, MS, Penthala, Narsimha R., PhD, Crooks, Peter A., PhD, DSc, Hann, Stephen R., PhD, Geng, Ling, MD, Balusu, Ramesh, PhD, Abbas, Tarek, PhD, Freeman, Michael L., PhD

Volltext

Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas von Stacy, Donnie R., Ely, Kim, Massion, Pierre P., Yarbrough, Wendell G., Hallahan, Dennis E., Sekhar, Konjeti R., Freeman, Michael L.

Volltext

Binding of Tritiated Sildenafil, Tadalafil, or Vardenafil to the Phosphodiesterase-5 Catalytic Site Displays Potency, Specificity, Heterogeneity, and cGMP Stimulation von Blount, Mitsi A., Beasley, Alfreda, Zoraghi, Roya, Sekhar, Konjeti R., Bessay, Emmanuel P., Francis, Sharron H., Corbin, Jackie D.

Volltext

Targeting NPM1 in irradiated cells inhibits NPM1 binding to RAD51, RAD51 foci formation and radiosensitizes NSCLC von Traver, Geri, Sekhar, Konjeti R., Crooks, Peter A., Keeney, Diane S., Freeman, Michael L.

Volltext