The growing impact of click chemistry on drug discovery von Kolb, Hartmuth C, Sharpless, K.Barry

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"On Water": Unique Reactivity of Organic Compounds in Aqueous Suspension von Narayan, Sridhar, Muldoon, John, Finn, M. G., Fokin, Valery V., Kolb, Hartmuth C., Sharpless, K. Barry

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Click Chemistry: Diverse Chemical Function from a Few Good Reactions von Kolb, Hartmuth C., Finn, M. G., Sharpless, K. Barry

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In Situ Selection of Lead Compounds by Click Chemistry:  Target-Guided Optimization of Acetylcholinesterase Inhibitors von Krasiński, Antoni, Radić, Zoran, Manetsch, Roman, Raushel, Jessica, Taylor, Palmer, Sharpless, K. Barry, Kolb, Hartmuth C.

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Inhibitors of HIV-1 Protease by Using In Situ Click Chemistry von Whiting, Matthew, Muldoon, John, Lin, Ying-Chuan, Silverman, Steven M., Lindstrom, William, Olson, Arthur J., Kolb, Hartmuth C., Finn, M. G., Sharpless, K. Barry, Elder, John H., Fokin, Valery V.

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Freeze-Frame Inhibitor Captures Acetylcholinesterase in a Unique Conformation von Bourne, Yves, Kolb, Hartmuth C., Radić, Zoran, Sharpless, K. Barry, Taylor, Palmer, Marchot, Pascale

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In Situ Click Chemistry:  Enzyme Inhibitors Made to Their Own Specifications von Manetsch, Roman, Krasiński, Antoni, Radić, Zoran, Raushel, Jessica, Taylor, Palmer, Sharpless, K. Barry, Kolb, Hartmuth C

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Multistep Synthesis of a Radiolabeled Imaging Probe Using Integrated Microfluidics von Lee, Chung-Cheng, Sui, Guodong, Elizarov, Arkadij, Shu, Chengyi Jenny, Shin, Young-Shik, Dooley, Alek N, Huang, Jiang, Daridon, Antoine, Wyatt, Paul, Stout, David, Kolb, Hartmuth C, Witte, Owen N, Satyamurthy, Nagichettiar, Heath, James R, Phelps, Michael E, Quake, Stephen R, Tseng, Hsian-Rong

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In Situ Click Chemistry: Enzyme-Generated Inhibitors of Carbonic Anhydrase II von Mocharla, Vani P., Colasson, Benoit, Lee, Lac V., Röper, Stefanie, Sharpless, K. Barry, Wong, Chi-Huey, Kolb, Hartmuth C.

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Catalytic Asymmetric Dihydroxylation von Kolb, Hartmuth C, VanNieuwenhze, Michael S, Sharpless, K. Barry

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Development of Tools for the Design of Selectin Antagonists von Kolb, Hartmuth C., Ernst, Beat

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A simplified procedure for the stereospecific transformation of 1,2-diols into epoxides von Kolb, Hartmuth C., Sharpless, K.Barry

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Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE von Bourne, Yves, Radić, Zoran, Kolb, Hartmuth C., Sharpless, K. Barry, Taylor, Palmer, Marchot, Pascale

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Toward an Understanding of the High Enantioselectivity in the Osmium-Catalyzed Asymmetric Dihydroxylation (AD). 1. Kinetics von Kolb, Hartmuth C, Andersson, Pher G, Sharpless, K. Barry

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Improved enantioselectivity in asymmetric dihydroxylations of terminal olefins using pyrimidine ligands von Crispino, Gerard A, Jeong, Kyu Sung, Kolb, Hartmuth C, Wang, Zhi Min, Xu, Daqiang, Sharpless, K. Barry

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Large-Scale and Highly Enantioselective Synthesis of the Taxol C-13 Side Chain through Asymmetric Dihydroxylation von Wang, Zhi-Min, Kolb, Hartmuth C, Sharpless, K. Barry

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Toward an Understanding of the High Enantioselectivity in the Osmium-Catalyzed Asymmetric Dihydroxylation. 4. Electronic Effects in Amine-Accelerated Osmylations von Nelson, Derek W, Gypser, Andreas, Ho, Pui Tong, Kolb, Hartmuth C, Kondo, Teruyuki, Kwong, Hoi-Lun, McGrath, Dominic V, Rubin, A. Erik, Norrby, Per-Ola, Gable, Kevin P, Sharpless, K. Barry

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Toward an Understanding of the High Enantioselectivity in the Osmium-Catalyzed Asymmetric Dihydroxylation. 2. A Qualitative Molecular Mechanics Approach von Norrby, Per-Ola, Kolb, Hartmuth C, Sharpless, K. Barry

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Efficient solution phase parallel synthesis of norstatine analogs von Voronkov, Michael V., Gontcharov, Alexander V., Wang, Zhi-Min, Richardson, Paul F., Kolb, Hartmuth C.

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Plasma pTau-217 and N-terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid-β positive individuals von Woo, MS, Tissot, C, Lantero-Rodriguez, J, Snellman, A, Therriault, J, Rahmouni, N, Macedo, AC, Servaes, S, Wang, YT, Arias, JF, Hosseini, SA, Chamoun, M, Lussier, FZ, Benedet, AL, Ashton, NJ, Karikari, TK, Triana-Baltzer, G, Kolb, HC, Stevenson, J, Mayer, C, Kobayashi, E, Massarweh, G, Friese, MA, Pascoal, TA, Gauthier, S, Zetterberg, H, Blennow, K, Rosa-Neto, P

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