Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia von McNeer, Nicole A., Philip, John, Geiger, Heather, Ries, Rhonda E., Lavallée, Vincent-Philippe, Walsh, Michael, Shah, Minita, Arora, Kanika, Emde, Anne-Katrin, Robine, Nicolas, Alonzo, Todd A., Kolb, E. Anders, Gamis, Alan S., Smith, Malcolm, Gerhard, Daniela Se, Guidry-Auvil, Jaime, Meshinchi, Soheil, Kentsis, Alex

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Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in Pediatric KMT2A-Rearranged AML: Results From the Phase III Children's Oncology Group Trial AAML0531 von Pollard, Jessica A., Guest, Erin, Alonzo, Todd A., Gerbing, Robert B., Loken, Mike R., Brodersen, Lisa Eidenschink, Kolb, E. Anders, Aplenc, Richard, Meshinchi, Soheil, Raimondi, Susana C., Hirsch, Betsy, Gamis, Alan S.

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The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models von Kendsersky, Nathan M., Lindsay, Jarrett, Kolb, E. Anders, Smith, Malcolm A., Teicher, Beverly A., Erickson, Stephen W., Earley, Eric J., Mosse, Yael P., Martinez, Daniel, Pogoriler, Jennifer, Krytska, Kateryna, Patel, Khushbu, Groff, David, Tsang, Matthew, Ghilu, Samson, Wang, Yifei, Seaman, Steven, Feng, Yang, St Croix, Brad, Gorlick, Richard, Kurmasheva, Raushan, Houghton, Peter J., Maris, John M.

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Evaluation of the pan‐class I phosphoinositide 3‐kinase (PI3K) inhibitor copanlisib in the Pediatric Preclinical Testing Consortium in vivo models of osteosarcoma von Harrison, Douglas, Gill, Jonathan, Roth, Michael, Hingorani, Pooja, Zhang, Wendong, Teicher, Beverly, Earley, Eric, Erickson, Stephen, Gatto, Gregory, Kumasheva, Raushan, Houghton, Peter, Smith, Malcolm, Anders Kolb, E., Gorlick, Richard

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Comprehensive Transcriptome Profiling of Cryptic CBFA2T3-GLIS2 Fusion-Positive AML Defines Novel Therapeutic Options: A COG and TARGET Pediatric AML Study von Smith, Jenny L., Ries, Rhonda E., Hylkema, Tiffany, Alonzo, Todd A., Gerbing, Robert B., Santaguida, Marianne T., Brodersen, Lisa Eidenschink, Pardo, Laura, Cummings, Carrie L., Loeb, Keith R., Le, Quy, Imren, Suzan, Leonti, Amanda R., Gamis, Alan S., Aplenc, Richard, Kolb, E. Anders, Farrar, Jason E., Triche, Timothy J., Nguyen, Cu, Meerzaman, Daoud, Loken, Michael R., Oehler, Vivian G., Bolouri, Hamid, Meshinchi, Soheil

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Insulin-like growth factor 1 receptor and response to anti-IGF1R antibody therapy in osteosarcoma von Cao, Yu, Roth, Michael, Piperdi, Sajida, Montoya, Kristofer, Sowers, Rebecca, Rao, Pulivarthi, Geller, David, Houghton, Peter, Kolb, E Anders, Gill, Jonathan, Gorlick, Richard

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MicroRNAs and Potential Targets in Osteosarcoma: Review von Sampson, Valerie B, Yoo, Soonmoon, Kumar, Asmita, Vetter, Nancy S, Kolb, E Anders

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Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models von Lowery, Caitlin D, Dowless, Michele, Renschler, Matthew, Blosser, Wayne, VanWye, Alle B, Stephens, Jennifer R, Iversen, Philip W, Lin, Aimee Bence, Beckmann, Richard P, Krytska, Kateryna, Cole, Kristina A, Maris, John M, Hawkins, Douglas S, Rubin, Brian P, Kurmasheva, Raushan T, Houghton, Peter J, Gorlick, Richard, Kolb, E Anders, Kang, Min H, Reynolds, C Patrick, Erickson, Stephen W, Teicher, Beverly A, Smith, Malcolm A, Stancato, Louis F

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Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia von Huang, Benjamin J., Smith, Jenny L., Farrar, Jason E., Wang, Yi-Cheng, Umeda, Masayuki, Ries, Rhonda E., Leonti, Amanda R., Crowgey, Erin, Furlan, Scott N., Tarlock, Katherine, Armendariz, Marcos, Liu, Yanling, Shaw, Timothy I., Wei, Lisa, Gerbing, Robert B., Cooper, Todd M., Gamis, Alan S., Aplenc, Richard, Kolb, E. Anders, Rubnitz, Jeffrey, Ma, Jing, Klco, Jeffery M., Ma, Xiaotu, Alonzo, Todd A., Triche, Timothy, Meshinchi, Soheil

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Whole genome and reverse protein phase array landscapes of patient derived osteosarcoma xenograft models von Wu, Chia-Chin, Huang, Licai, Zhang, Zhongting, Ju, Zhenlin, Song, Xingzhi, Kolb, E. Anders, Zhang, Wendong, Gill, Jonathan, Ha, Min, Smith, Malcolm A., Houghton, Peter, Morton, Christopher L., Kurmasheva, Raushan, Maris, John, Mosse, Yael, Lu, Yiling, Gorlick, Richard, Futreal, P. Andrew, Beird, Hannah C.

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Clinical relevance of proteomic profiling in de novo pediatric acute myeloid leukemia: a Children's Oncology Group study von Hoff, Fieke W, Van Dijk, Anneke D, Qiu, Yihua, Hu, Chenyue W, Ries, Rhonda E, Ligeralde, Andrew, Jenkins, Gaye N, Gerbing, Robert B, Gamis, Alan S, Aplenc, Richard, Kolb, E Anders, Alonzo, Todd A, Meshinchi, Soheil, Qutub, Amina A, De Bont, Eveline S J M, Horton, Terzah M, Kornblau, Steven M

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Vorinostat Enhances Cytotoxicity of SN-38 and Temozolomide in Ewing Sarcoma Cells and Activates STAT3/AKT/MAPK Pathways von Sampson, Valerie B, Vetter, Nancy S, Kamara, Davida F, Collier, Anderson B, Gresh, Renee C, Kolb, E Anders

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CD81 knockout promotes chemosensitivity and disrupts in vivo homing and engraftment in acute lymphoblastic leukemia von Quagliano, Anthony, Gopalakrishnapillai, Anilkumar, Kolb, E. Anders, Barwe, Sonali P.

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A review of targeted therapies evaluated by the pediatric preclinical testing program for osteosarcoma von Sampson, Valerie B, Gorlick, Richard, Kamara, Davida, Anders Kolb, E

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Distinct age-associated molecular profiles in acute myeloid leukemia defined by comprehensive clinical genomic profiling von Tarlock, Katherine, Zhong, Shan, He, Yuting, Ries, Rhonda, Severson, Eric, Bailey, Mark, Morley, Samantha, Balasubramanian, Sohail, Erlich, Rachel, Lipson, Doron, Otto, Geoff A, Vergillo, Jo-Anne, Kolb, E Anders, Ross, Jeffrey S, Mughal, Tariq, Stephens, Philip J, Miller, Vincent, Meshinchi, Soheil, He, Jie

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Initial testing of the aurora kinase a inhibitor MLN8237 by the Pediatric Preclinical Testing Program (PPTP) von Maris, John M., Morton, Christopher L., Gorlick, Richard, Kolb, E. Anders, Lock, Richard, Carol, Hernan, Keir, Stephen T., Reynolds, C. Patrick, Kang, Min H., Wu, Jianrong, Smith, Malcolm A., Houghton, Peter J.

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Preclinical evaluation of the combination of AZD1775 and irinotecan against selected pediatric solid tumors: A Pediatric Preclinical Testing Consortium report von Kolb, E. Anders, Houghton, Peter J., Kurmasheva, Raushan T., Mosse, Yael P., Maris, John M., Erickson, Stephen W., Guo, Yuelong, Teicher, Beverly A., Smith, Malcolm A., Gorlick, Richard

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Disease Characteristics and Prognostic Implications of Cell-Surface FLT3 Receptor (CD135) Expression in Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Grou... von Tarlock, Katherine, Alonzo, Todd A, Loken, Michael R, Gerbing, Robert B, Ries, Rhonda E, Aplenc, Richard, Sung, Lillian, Raimondi, Susana C, Hirsch, Betsy A, Kahwash, Samir B, McKenney, Amy, Kolb, E Anders, Gamis, Alan S, Meshinchi, Soheil

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Modeling Transient Abnormal Myelopoiesis Using Induced Pluripotent Stem Cells and CRISPR/Cas9 Technology von Barwe, Sonali P., Sidhu, Ishnoor, Kolb, E. Anders, Gopalakrishnapillai, Anilkumar

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Initial testing (stage 1) of a monoclonal antibody (SCH 717454) against the IGF-1 receptor by the pediatric preclinical testing program von Kolb, E. Anders, Gorlick, Richard, Houghton, Peter J., Morton, Christopher L., Lock, Richard, Carol, Hernan, Reynolds, C. Patrick, Maris, John M., Keir, Stephen T., Billups, Catherine A., Smith, Malcolm A.

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