Synergy between methionine stress and chemotherapy in the treatment of brain tumor xenografts in athymic mice von KOKKINAKIS, Demetrius M, HOFFMAN, Robert M, FRENKEL, Eugene P, WICK, Jacquelynn B, QINGHONG HAN, MINGXU XU, YUYING TAN, SCHOLD, S. Clifford

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Aberrant Wnt/β-Catenin Signaling in Pancreatic Adenocarcinoma von Zeng, Gang, Germinaro, Matt, Micsenyi, Amanda, Monga, Navjot K., Bell, Aaron, Sood, Ajit, Malhotra, Vanita, Sood, Neena, Midda, Vandana, Monga, Dulabh K., Kokkinakis, Demetrius M., Monga, Satdarshan P.S.

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High yields of K-ras mutations in intraductal papillary mucinous tumors and invasive adenocarcinomas induced by N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine in the pancreas of fema... von Sugio, Kenji, Gazdar, Adi F., Albores-Saavedra, Jorge, Kokkinakis, Demetrius M.

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The significance of DNA damage, its repair and cell proliferation during carcinogen treatment in the initiation of pancreatic cancer in the hamster model von KOKKINAKIS, D. M, SUBBARAO, V

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Glial Tumors in the MNU Rat Model: Induction of Pure and Mixed Gliomas that Do Not Require Typical Missense Mutations of p53 von Rushing, Elisabeth J, Watson, Mark L, Schold, S Clifford, Land, Kevin J, Kokkinakis, Demetrius M

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Physiology and Gene Expression Characteristics of Carcinogen-Initiated and Tumor-Transformed Glial Progenitor Cells Derived from the CNS of Methylnitrosourea (MNU)-Treated Sprague-... von KOKKINAKIS, DEMETRIUS M, RUSHING, ELISABETH J, SHAREEF, MOHAMMED M, AHMED, MANSOOR M, YANG, SHUTING, SINGHA, UJJAL K, LUO, JIANHUA

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Orotic acid enhancement of preneoplastic and neoplastic lesions induced in the pancreas and liver of hamsters by N-nitroso(2-hydroxypropyl) (2-oxopropyl)amine von KOKKINAKIS, D. M, ALBORES-SAAVEDRA, J

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Metabolic Response of Normal and Malignant Tissue to Acute and Chronic Methionine Stress in Athymic Mice Bearing Human Glial Tumor Xenografts von Kokkinakis, Demetrius M, Wick, Jacquellyn B, Zhou, Qing Xian

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Alkylation of rodent tissue DNA induced by N-nitrosobis(2-hydroxypropyl)amine von KOKKINAKIS, D. M

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Regulation of O6-methylguanine-DNA methyltransferase by methionine in human tumour cells von Kokkinakis, DM, von Wronski, MA, Vuong, TH, Brent, TP, Schold, SC

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Phase I trial of O6-benzylguanine for patients undergoing surgery for malignant glioma von FRIEDMAN, H. S, KOKKINAKIS, D. M, MOSCHEL, R. C, MCLENDON, R. E, KERBY, T, HERNDON, J. E, BIGNER, D. D, SCHOLD, S. C, PLUDA, J, FRIEDMAN, A. H, COKGOR, I, HAGLUND, M. M, ASHLEY, D. M, RICH, J, DOLAN, M. E, PEGG, A. E

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Species differences in the metabolism of N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine von Kokkinakis, Demetri M., Scarpelli, Dante G., Subbarao, Vadrevu, Hollenberg, Paul F.

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Metabolism and activation of pancreas specific nitrosamines by pancreatic ductal cells in culture von Kokkinakis, Demetrius M., Reddy, M. Kumudavalli, Norgle, Jeffrey R., Baskaran, Kathirvelu

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Differences between pancreatropic nitrosamine carcinogens and N-nitrosodimethylamine in methylating DNA in various tissues of hamsters and rats von Kokkinakis, Demetrius M.

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Enhancement of N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine-induced tumorigenesis in Sprague-Dawley rats by orotic acid von KOKKINAKIS, D. M, SCARPELLI, D. G, OYASU, R

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Multifaceted Resistance of Gliomas to Temozolomide von BOCANGEL, Dora B, FINKELSTEIN, Sydney, SCHOLD, S. Clifford, BHAKAT, Kishor K, MITRA, Sankar, KOKKINAKIS, Demetrius M

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Modulation of cell cycle and gene expression in pancreatic tumor cell lines by methionine deprivation (methionine stress): implications to the therapy of pancreatic adenocarcinoma von Kokkinakis, Demetrius M, Liu, Xiaoyan, Neuner, Russell D

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Eradication of Human Medulloblastoma Tumor Xenografts with a Combination of O6-Benzyl-2′-deoxyguanosine and 1,3-Bis(2-chloroethyl)-1-nitrosourea von KOKKINAKIS, D. M, MOSCHEL, R. C, PEGG, A. E, SCHOLD, S. C

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Carcinogenicity of N-nitroso(2-hydroxypropyl)(2-oxopropyl)amine, N-nitrosobis(2-hydroxypropyl)amine and cis-N-nitroso-2,6-dimethylmorpholine administered continuously in the Syrian... von Kokkinakis, Demetrius M., Scarpelli, Dante G.

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Methionine-stress: A pleiotropic approach in enhancing the efficacy of chemotherapy von Kokkinakis, Demetrius M.

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