Feasibility and repeatability of optical coherence tomography measurements of pre-stent thrombus burden in patients with STEMI treated with primary PCI von Kajander, Olli A, Koistinen, Laura S, Eskola, Markku, Huhtala, Heini, Bhindi, Ravinay, Niemelä, Kari, Jolly, Sanjit S, Sheth, Tej

Volltext

Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle von Taylor, D. Leland, Jackson, Anne U., Narisu, Narisu, Hemani, Gibran, Erdos, Michael R., Chines, Peter S., Swift, Amy, Idol, Jackie, Didion, John P., Welch, Ryan P., Kinnunen, Leena, Saramies, Jouko, Lakka, Timo A., Laakso, Markku, Tuomilehto, Jaakko, Parker, Stephen C. J., Koistinen, Heikki A., Smith, George Davey, Boehnke, Michael, Scott, Laura J., Birney, Ewan, Collins, Francis S.

Volltext

Abstract 1868: Glycodelin-producing endometrial adenocarcinoma cells are resistant to TGFβ von Hautala, Laura, Koistinen, Hannu

Volltext

Abstract 601: Glycodelin expression in lung cancer and melanoma von Hautala, Laura, Koistinen, Hannu

Volltext

The genetic regulatory signature of type 2 diabetes in human skeletal muscle von Scott, Laura J., Erdos, Michael R., Huyghe, Jeroen R., Welch, Ryan P., Beck, Andrew T., Wolford, Brooke N., Chines, Peter S., Didion, John P., Narisu, Narisu, Stringham, Heather M., Taylor, D. Leland, Jackson, Anne U., Vadlamudi, Swarooparani, Bonnycastle, Lori L., Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Albanus, Ricardo D'Oliveira, Kiseleva, Anna, Hensley, John, Crawford, Gregory E., Jiang, Hui, Wen, Xiaoquan, Watanabe, Richard M., Lakka, Timo A., Mohlke, Karen L., Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A., Boehnke, Michael, Collins, Francis S., Parker, Stephen C. J.

Volltext

Repressed PKCδ activation in glycodelin-expressing cells mediates resistance to phorbol ester and TGFβ von Hautala, Laura C, Koistinen, Riitta, Koistinen, Hannu

Volltext

Abstract 4066: Glycodelin abolishes PMA-induced migration of MCF-7 breast cancer cells von Hautala, Laura C., Koistinen, Riitta, Koistinen, Hannu

Volltext

Interactions between genetic variation and cellular environment in skeletal muscle gene expression von Taylor, D Leland, Knowles, David A, Scott, Laura J, Ramirez, Andrea H, Casale, Francesco Paolo, Wolford, Brooke N, Guan, Li, Varshney, Arushi, Albanus, Ricardo D'Oliveira, Parker, Stephen C J, Narisu, Narisu, Chines, Peter S, Erdos, Michael R, Welch, Ryan P, Kinnunen, Leena, Saramies, Jouko, Sundvall, Jouko, Lakka, Timo A, Laakso, Markku, Tuomilehto, Jaakko, Koistinen, Heikki A, Stegle, Oliver, Boehnke, Michael, Birney, Ewan, Collins, Francis S

Volltext

ACE2 expression in adipose tissue is associated with cardio-metabolic risk factors and cell type composition—implications for COVID-19 von El-Sayed Moustafa, Julia S., Jackson, Anne U., Brotman, Sarah M., Guan, Li, Villicaña, Sergio, Roberts, Amy L., Zito, Antonino, Bonnycastle, Lori, Erdos, Michael R., Narisu, Narisu, Stringham, Heather M., Welch, Ryan, Yan, Tingfen, Lakka, Timo, Parker, Stephen, Tuomilehto, Jaakko, Seow, Jeffrey, Graham, Carl, Huettner, Isabella, Acors, Sam, Kouphou, Neophytos, Wadge, Samuel, Duncan, Emma L., Steves, Claire J., Doores, Katie J., Malim, Michael H., Collins, Francis S., Pajukanta, Päivi, Boehnke, Michael, Koistinen, Heikki A., Laakso, Markku, Falchi, Mario, Bell, Jordana T., Scott, Laura J., Mohlke, Karen L., Small, Kerrin S.

Volltext

A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emis... von Latva-Rasku, Aino, Honka, Miikka-Juhani, Stančáková, Alena, Koistinen, Heikki A, Kuusisto, Johanna, Guan, Li, Manning, Alisa K, Stringham, Heather, Gloyn, Anna L, Lindgren, Cecilia M, Collins, Francis S, Mohlke, Karen L, Scott, Laura J, Karjalainen, Tomi, Nummenmaa, Lauri, Boehnke, Michael, Nuutila, Pirjo, Laakso, Markku

Volltext

High-grade ovarian serous carcinoma patients exhibit profound alterations in lipid metabolism von Braicu, Elena Ioana, Darb-Esfahani, Silvia, Schmitt, Wolfgang D, Koistinen, Kaisa M, Heiskanen, Laura, Pöhö, Päivi, Budczies, Jan, Kuhberg, Marc, Dietel, Manfred, Frezza, Christian, Denkert, Carsten, Sehouli, Jalid, Hilvo, Mika

Volltext

Utö Observatory for Analysing Atmospheric Ducting Events over Baltic Coastal and Marine Waters von Rautiainen, Laura, Tyynelä, Jani, Lensu, Mikko, Siiriä, Simo, Vakkari, Ville, O’Connor, Ewan, Hämäläinen, Karoliina, Lonka, Harry, Stenbäck, Ken, Koistinen, Jarmo, Laakso, Lauri

Volltext

Altered glycosylation of glycodelin in endometrial carcinoma von Hautala, Laura C., Pang, Poh-Choo, Antonopoulos, Aristotelis, Pasanen, Annukka, Lee, Cheuk-Lun, Chiu, Philip C.N., Yeung, William S.B., Loukovaara, Mikko, Bützow, Ralf, Haslam, Stuart M., Dell, Anne, Koistinen, Hannu

Volltext

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability von Lagou, Vasiliki, Mägi, Reedik, Grallert, Harald, Jansen, Rick, Dimas, Antigone S., Ulrich, Anna, Zudina, Liudmila, Gådin, Jesper R., Faggian, Alessia, Tanaka, Toshiko, Webster, Rebecca J., Saxena, Richa, Salo, Perttu, Shin, So-Youn, Amin, Najaf, Li, Guo, Verweij, Niek, Johnson, Paul C. D., Johnson, Toby, Rasmussen-Torvik, Laura J., Esko, Tõnu, Fall, Tove, Fraser, Ross M., Kanoni, Stavroula, Giedraitis, Vilmantas, Kleber, Marcus E., Sanna, Serena, Boettcher, Yvonne, Rayner, N. William, Nolte, Ilja M., Iperen, Erik van, Kovacs, Peter, Campbell, Susan, Polasek, Ozren, Egan, Josephine, Kiess, Wieland, Willemsen, Gonneke, Kuusisto, Johanna, Laakso, Markku, Thorand, Barbara, Miljkovic, Iva, Lind, Lars, Doney, Alex, Perola, Markus, Kivimaki, Mika, Kumari, Meena, Bennett, Amanda J., Groves, Christopher J., Koistinen, Heikki A., Bakker, Stephan J. L., Uusitupa, Matti, Palmer, Colin N. A., Pouta, Anneli, Krus, Ulrika, de Geus, Eco J. C. N., Wolffenbuttel, Bruce H. R., Abecasis, Goncalo R., Wright, Alan F., Dedoussis, George V., Schwarz, Peter E. H., Winkelmann, Bernhard R., Boehm, Bernhard O., März, Winfried, Metspalu, Andres, Price, Jackie F., Keinanen-Kiukaanniemi, Sirkka M., Saaristo, Timo E., Bergman, Richard N., Tuomilehto, Jaakko, Langenberg, Claudia, Vitart, Veronique, Visvikis-Siest, Sophie, Altshuler, David, Illig, Thomas, Ferrucci, Luigi, Pramstaller, Peter P., Peyser, Patricia A., Palmer, Lyle J., Penninx, Brenda W., Harst, Pim van der, Forouhi, Nita G., Loos, Ruth J. F., Boomsma, Dorret I., Hofman, Albert, Munroe, Patricia B., Gudnason, Vilmundur, Stefansson, Kari, Hamsten, Anders, Nicholson, George, Dermitzakis, Emmanouil T., Lindgren, Cecilia M., Froguel, Philippe, Kaakinen, Marika A., Lyssenko, Valeriya, Watanabe, Richard M., Ingelsson, Erik, Florez, Jose C., Barroso, Inês, Morris, Andrew P., Prokopenko, Inga

Volltext

Abstract 436: Glycodelin expression in endometrial carcinoma von Koistinen, Hannu, Pasanen, Annukka, Hautala, Laura

Volltext

Abstract 3265: PMA induces malignant characteristics in MCF-7 breast cancer cells via MAPK-pathway von Hautala, Laura C., Koistinen, Riitta, Koistinen, Hannu

Volltext

210-OR: ADA Presidents' Select Abstract: Discovering Stimulatory State-Specific Type 2 Diabetes GWAS Mechanisms with Single-Cell Multiomics on iPSC-Derived Fibro-adipogenic Progeni... von Ventresca, Christa, Varshney, Arushi, Orchard, Peter, Tsan, Yao-Chang, Da Rocha, Andre Monteiro, Laakso, Markku, Tuomilehto, Jaakko, Lakka, Timo A, Mohlke, Karen L, Boehnke, Michael, Scott, Laura, Koistinen, Heikki A, Collins, Francis S, Herron, Todd J, Bielas, Stephanie, Parker, Stephen

Volltext

213-OR: Widespread Age-Associated Changes in the Chromatin Architecture of Skeletal Muscle Cell Types von Moo, Keagan G, Albanus, Ricardo D'Oliveira, Varshney, Arushi, Orchard, Peter, Manickam, Nandini, Laakso, Markku, Tuomilehto, Jaakko, Lakka, Timo A, Mohlke, Karen L, Boehnke, Michael, Scott, Laura, Koistinen, Heikki A, Collins, Francis S, Parker, Stephen

Volltext

2012-LB: Type 2 Diabetes GWAS Signal C2CD4A/B Insulin Resistance Mechanisms in Skeletal Muscle von Epelle, Ibiere L, Varshney, Arushi, Orchard, Peter, Zhang, Zhenhao, Feng, Fan, Laakso, Markku, Tuomilehto, Jaakko, Lakka, Timo A, Mohlke, Karen L, Boehnke, Michael, Scott, Laura, Koistinen, Heikki A, Collins, Francis S, Liu, Jie, Parker, Stephen C

Volltext

274-OR: Population-Scale Single-Nucleus Skeletal Muscle Chromatin Dynamics and Nucleosome Positioning in the Context of Type 2 Diabetes von Wang, Xiaoou, Robertson, Cassie, Varshney, Arushi, Manickam, Nandini, Orchard, Peter, Laakso, Markku, Tuomilehto, Jaakko, Lakka, Timo A, Mohlke, Karen L, Boehnke, Michael, Scott, Laura, Koistinen, Heikki A, Collins, Francis S, Parker, Stephen

Volltext