Metabolic milieu associates with impaired skeletal characteristics in obesity von Viljakainen, Heli T, Koistinen, Heikki A, Tervahartiala, Taina, Sorsa, Timo, Andersson, Sture, Mäkitie, Outi

Volltext

A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism von Seldin, Marcus M., Koplev, Simon, Rajbhandari, Prashant, Vergnes, Laurent, Rosenberg, Gregory M., Meng, Yonghong, Pan, Calvin, Phuong, Thuy M.N., Gharakhanian, Raffi, Che, Nam, Mäkinen, Selina, Shih, Diana M., Civelek, Mete, Parks, Brian W., Kim, Eric D., Norheim, Frode, Chella Krishnan, Karthickeyan, Hasin-Brumshtein, Yehudit, Mehrabian, Margarete, Laakso, Markku, Drevon, Christian A., Koistinen, Heikki A., Tontonoz, Peter, Reue, Karen, Cantor, Rita M., Björkegren, Johan L.M., Lusis, Aldons J.

Volltext

Signaling Specificity of Interleukin-6 Action on Glucose and Lipid Metabolism in Skeletal Muscle von Al-Khalili, Lubna, Bouzakri, Karim, Glund, Stephan, Lönnqvist, Fredrik, Koistinen, Heikki A, Krook, Anna

Volltext

Interleukin-6 Directly Increases Glucose Metabolism in Resting Human Skeletal Muscle von Glund, Stephan, Deshmukh, Atul, Long, Yun Chau, Moller, Theodore, Koistinen, Heikki A, Caidahl, Kenneth, Zierath, Juleen R, Krook, Anna

Volltext

siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle von Bouzakri, Karim, Zachrisson, Anna, Al-Khalili, Lubna, Zhang, Bei B., Koistinen, Heikki A., Krook, Anna, Zierath, Juleen R.

Volltext

5-Amino-Imidazole Carboxamide Riboside Increases Glucose Transport and Cell-Surface GLUT4 Content in Skeletal Muscle From Subjects With Type 2 Diabetes von KOISTINEN, Heikki A, GALUSKA, Dana, CHIBALIN, Alexander V, JING YANG, ZIERATH, Juleen R, HOLMAN, Geoffrey D, WALLBERG-HENRIKSSON, Harriet

Volltext

Analysis of paradoxical observations on the association between leptin and insulin resistance von Ceddia, Rolando B., Koistinen, Heikki A., Zierath, Juleen R., Sweeney, Gary

Volltext

Nitric oxide increases cyclic GMP levels, AMP-activated protein kinase (AMPK)α1-specific activity and glucose transport in human skeletal muscle von Deshmukh, A. S, Long, Y. C, de Castro Barbosa, T, Karlsson, H. K. R, Glund, S, Zavadoski, W. J, Gibbs, E. M, Koistinen, H. A, Wallberg-Henriksson, H, Zierath, J. R

Volltext

Kinetics of GLUT4 Trafficking in Rat and Human Skeletal Muscle von KARLSSON, Hakan K. R, CHIBALIN, Alexander V, KOISTINEN, Heikki A, JING YANG, KOUMANOV, Francoise, WALLBERG-HENRIKSSON, Harriet, ZIERATH, Juleen R, HOLMAN, Geoffrey D

Volltext

Aberrant p38 mitogen-activated protein kinase signalling in skeletal muscle from Type 2 diabetic patients von KOISTINEN, H. A, CHIBALIN, A. V, ZIERATH, J. R

Volltext

Insulin Signaling and Glucose Transport in Skeletal Muscle From First-Degree Relatives of Type 2 Diabetic Patients von KARLSSON, Hakan K. R, AHLSEN, Maria, ZIERATH, Juleen R, WALLBERG-HENRIKSSON, Harriet, KOISTINEN, Heikki A

Volltext

Postnatal changes in concentrations of free and bound leptin von Hytinantti, T K, Juntunen, M, Koistinen, H A, Koivisto, V A, Karonen, S-L, Andersson, S

Volltext

USF1 and dyslipidemias: converging evidence for a functional intronic variant von Naukkarinen, Jussi, Gentile, Massimiliano, Soro-Paavonen, Aino, Saarela, Janna, Koistinen, Heikki A., Pajukanta, Päivi, Taskinen, Marja-Riitta, Peltonen, Leena

Volltext

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls von Flannick, J, Mercader, JM, Fuchsberger, C, Udler, MS, Teslovich, TM, Caulkins, L, Blackwell, TW, Brody, JA, Chen, L, Córdova, E, Dolan, L, Elliott, A, Floyd, JS, Gabriel, S, Garay-Sevilla, ME, García-Ortiz, H, Gross, M, Han, S, Heard-Costa, NL, Jackson, AU, Kelsey, M, Kim, B-J, Koistinen, HA, Leader, JB, Liu, C-T, Lyssenko, V, Marcketta, A, Malacara-Hernandez, JM, Matsuo, K, Mayer-Davis, E, Mendoza-Caamal, E, Ng, MCY, O'Dushlaine, C, Post, WS, Psaty, BM, Vasan, RS, Revilla-Monsalve, C, Robertson, NR, Santoro, N, Strom, TM, Tam, CHT, Thameem, F, Tomlinson, B, Torres, JM, Van Dam, RM, Vujkovic, M, Wang, S, Witte, DR, Barzilai, N, Blangero, J, Bowden, DW, Chan, E, Collins, FS, De Vries, PS, Glaser, B, Groop, L, Kooner, JS, Laakso, M, Lehman, DM, Nilsson, P, Tuomi, T, Aguilar-Salinas, CA, Bottinger, E, Chan, JCN, Dupuis, J, Frossard, P, Kim, YJ, Lee, J-Y, Loos, RJF, Ma, RCW, Morris, AD, Pankow, J, Saleheen, D, Sim, X, Small, KS, Haiman, C, Orozco, L, Tusié-Luna, T, Gieger, C, Meitinger, T, Strauch, K, Hansen, T, Zeitler, P, Dabelea, D, Abecasis, G, Bell, GI, Cox, NJ, Seielstad, M, Meigs, JB, Rich, SS, Rotter, JI, DiscovEHR Collaboration, CHARGE, GoT2D, SIGMA-T2D, T2D-GENES, Altshuler, D, Burtt, NP, Morris, AP, Florez, JC

Volltext

Relationship Between Serum Amyloid A Level and Tanis/SelS mRNA Expression in Skeletal Muscle and Adipose Tissue From Healthy and Type 2 Diabetic Subjects von KARLSSON, Hakan K. R, TSUCHIDA, Hiroki, LAKE, Staffan, KOISTINEN, Heikki A, KROOK, Anna

Volltext

Regulation of glucose transport in human skeletal muscle von Koistinen, H.A, Zierath, J.R

Volltext

An expanded genome-wide association study of Type 2 diabetes in Europeans von Mägi, R, Gaulton, KJ, Kaakinen, M, Pervjakova, N, Pers, TH, Johnson, AD, Eicher, JD, Ferreira, T, Ma, C, Thorleifsson, G, Qi, L, Van Zuydam, NR, Mahajan, A, Almgren, P, Voight, BF, Müller-Nurasyid, M, Ried, JS, Rayner, WN, Robertson, N, Karssen, LC, Willems, SM, Chanda, P, Li, M, Lu, Y, Yengo, L, Jiang, L, Chheda, H, Eisele, L, Gustafsson, S, Frånberg, M, Benediktsson, R, Kong, A, Sigurðsson, G, Kerrison, ND, Luan, J, Meitinger, T, Esko, T, Liu, CT, Isomaa, B, Couper, DJ, Pankow, JS, Cornelis, MC, Kraft, P, Owen, KR, Zeggini, E, Tajes-Fernandes, J, Chines, PS, Stringham, HM, Koistinen, HA, Kinnunen, L, Sennblad, B, Mühleisen, TW, Nöthen, MM, Baldassarre, D, Gertow, K, Humphries, SE, Tremoli, E, Klopp, N, Meyer, J, Steinbach, G, Mӓnnistö, S, Tikkanen, E, Eury, E, Lobbens, S, Leander, K, Blüher, M, Kovacs, P, Maruthur, NM, Erbel, R, De Faire, U, Hamsten, A, Deloukas, P, Donnelly, PJ, Frayling, TM, Hattersley, AT, Ripatti, S, Boehm, BO, Collins, FS, Pedersen, O, Barroso, I, Froguel, P, Balkau, B, Franks, PW, Gurrea, AB, Palli, D, Altshuler, D, Groop, LC, Langenberg, C, Wareham, NJ, Florez, JC, Meigs, JB, Boerwinkle, E, Strauch, K, Metspalu, A, Palmer, CN, Hu, FB, Dupuis, J, Boehnke, M, McCarthy, MI, DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium

Volltext

Fatty acid transport protein-1 mRNA expression in skeletal muscle and in adipose tissue in humans von Binnert, Christophe, Koistinen, Heikki A, Martin, Genevieve, Andreelli, Fabrizio, Ebeling, Pertti, Koivisto, Veikko A, Laville, Martine, Auwerx, Johan, Vidal, Hubert

Volltext

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass von Zillikens, MC, Hsu, Y-H, Yerges-Armstrong, LM, Chou, W-C, Stolk, L, Johnson, T, Koller, DL, Luan, J, Ried, JS, Thorleifsson, G, Vandenput, L, Zhao, JH, Bennett, DA, Biffar, R, Bochud, M, Borecki, IB, Campbell, H, Cauley, JA, Cederberg, H, Cho, NH, Choi, HJ, Claussnitzer, M, Collins, F, Cummings, SR, De Jager, PL, Demuth, I, Diatchenko, L, Eiriksdottir, G, Enneman, AW, Erdos, M, Eriksson, JG, Estrada, K, Evans, DS, Fu, M, Garcia, M, Gieger, C, Girke, T, Grallert, H, Grewal, J, Han, B-G, Hayward, C, Hofman, A, Hoffman, EP, Hsueh, W-C, Huffman, KM, Ittermann, T, Jordan, JM, Kilpelanen, TO, Kloth, JSL, Koistinen, HA, Kritchevsky, S, Laakso, M, Lang, T, Langdahl, BL, Lee, J-Y, Lerch, MM, Liu, Y, Lorentzon, M, Mellstrom, D, Melov, S, Michaelsson, K, Mitchell, BD, Morris, AP, Newman, A, Nielson, CM, Palotie, A, Parker, SCJ, Peters, A, Polasek, O, Ripatti, S, Robbins, JA, Rotter, JI, Rudan, I, Sehmi, J, Soranzo, N, Stancakova, A, Steinhagen-Thiessen, E, Styrkarsdottir, U, Swart, KMA, Tarnopolsky, MA, Thompson, P, Thomson, CA, Thorsteinsdottir, U, Tranah, GJ, Tuomilehto, J, Van Schoor, NM, Wactawski-Wende, J, Walker, M, Weedon, MN, Wichmann, H-E, Widen, E, Wilson, JF, Wright, NC, Xie, W, Doring, A, Rivadeneira, F, Wareham, NJ, Waterworth, D, Loos, RJF, Kiel, DP

Volltext

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass von Zillikens, MC, Hsu, Y-H, Yerges-Armstrong, LM, Chou, W-C, Stolk, L, Johnson, T, Koller, DL, Luan, J, Ried, JS, Thorleifsson, G, Vandenput, L, Zhao, JH, Bennett, DA, Biffar, R, Bochud, M, Borecki, IB, Campbell, H, Cauley, JA, Cederberg, H, Cho, NH, Choi, HJ, Claussnitzer, M, Collins, F, Cummings, SR, De Jager, PL, Demuth, I, Diatchenko, L, Eiriksdottir, G, Enneman, AW, Erdos, M, Eriksson, JG, Estrada, K, Evans, DS, Fu, M, Garcia, M, Gieger, C, Girke, T, Grallert, H, Grewal, J, Han, B-G, Hayward, C, Hofman, A, Hoffman, EP, Hsueh, W-C, Huffman, KM, Ittermann, T, Jordan, JM, Kloth, JSL, Koistinen, HA, Kritchevsky, S, Laakso, M, Lang, T, Langdahl, BL, Lee, J-Y, Lerch, MM, Liu, Y, Lorentzon, M, McGuigan, FE, Mellstrom, D, Melov, S, Michaelsson, K, Mitchell, BD, Morris, AP, Newman, A, Nielson, CM, Palotie, A, Peters, A, Polasek, O, Ripatti, S, Robbins, JA, Rotter, JI, Rudan, I, Sehmi, J, Shen, J, Soranzo, N, Stancakova, A, Steinhagen-Thiessen, E, Styrkarsdottir, U, Swart, KMA, Tarnopolsky, MA, Thompson, P, Thomson, CA, Thorsteinsdottir, U, Tranah, GJ, Tuomilehto, J, Van Schoor, NM, Voelzke, H, Wactawski-Wende, J, Walker, M, Weedon, MN, Widen, E, Wilson, JF, Wright, NC, Xie, W, Doring, A, Rivadeneira, F, Wareham, NJ, Waterworth, D, Loos, RJF, Kiel, DP

Volltext