MEK (MAPKK) inhibitors. Part 2: structure–activity relationships of 4-anilino-3-cyano-6,7-dialkoxyquinolines von Zhang, Nan, Wu, Biqi, Eudy, Nancy, Wang, Yanong, Ye, Fei, Powell, Dennis, Wissner, Allan, Feldberg, Larry R., Kim, Steven C., Mallon, Robert, Kovacs, Eleonora D., Toral-Barza, Lourdes, Kohler, Constance A.

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Analogs of platelet activating factor. 7. Bis-aryl amide and bis-aryl urea receptor antagonists of PAF von Wissner, Allan, Carroll, Marion L, Johnson, Bernard D, Kerwar, Suresh S, Pickett, Walter C, Schaub, Robert E, Torley, Lawrence W, Trova, Michael P, Kohler, Constance A

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Analogs of platelet activating factor. 8. Antagonists of PAF containing an aromatic ring linked to a pyridinium ring von Trova, Michael P, Wissner, Allan, Carroll, Marion L, Kerwar, Suresh S, Pickett, Walter C, Schaub, Robert E, Torley, Lawrence W, Kohler, Constance A

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Automated platelet aggregation analysis using a digitizer von Kohler, Constance A., Zoltan, Bart J.

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Can fecal continence be predicted in patients born with anorectal malformations? von Minneci, Peter C., Kabre, Rashmi S., Mak, Grace Z., Halleran, Devin R., Cooper, Jennifer N., Afrazi, Amin, Calkins, Casey M., Corkum, Kristine, Downard, Cynthia D., Ehrlich, Peter, Fraser, Jason D., Gadepalli, Samir K., Helmrath, Michael A., Kohler, Jonathan E., Landisch, Rachel, Landman, Matthew P., Lee, Constance, Leys, Charles M, Lodwick, Daniel L., McLeod, Jennifer, Mon, Rodrigo, McClure, Beth, Rymeski, Beth, Saito, Jacqueline M., Sato, Thomas T., St. Peter, Shawn D., Wood, Richard, Levitt, Marc A., Deans, Katherine J.

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Screening practices and associated anomalies in infants with anorectal malformations: Results from the Midwest Pediatric Surgery Consortium von Minneci, Peter C., Kabre, Rashmi S., Mak, Grace Z., Halleran, Devin R., Cooper, Jennifer N., Afrazi, Amin, Calkins, Casey M., Downard, Cynthia D., Ehrlich, Peter, Fraser, Jason, Gadepalli, Samir K., Helmrath, Michael A., Kohler, Jonathan E., Landisch, Rachel, Landman, Matthew P., Lee, Constance, Leys, Charles M, Lodwick, Daniel L., Mon, Rodrigo, McClure, Beth, Rymeski, Beth, Saito, Jacqueline M., Sato, Thomas T., St. Peter, Shawn D., Wood, Richard, Levitt, Marc A., Deans, Katherine J.

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CD33 CAR T-Cells (CD33CART) for Children and Young Adults with Relapsed/Refractory AML: Dose-Escalation Results from a Phase I/II Multicenter Trial von Shah, Nirali N., Tasian, Sarah K., Kohler, M. Eric, Hsieh, Emily M., Baumeister, Susanne H.C., Summers, Corinne, Shalabi, Haneen, Pollard, Jessica A., Yates, Bonnie, Brazauskas, Ruta, Ndifon, Eric, Yuan, Constance M., Wang, Hao-Wei, Kobusingye, Hati K, Christianson, Kayla, Weiss, Allison A, Leckrone, Erin, Shaw, Bronwen E., Auletta, Jeffery J., Rangarajan, Hemalatha G., Roach, John, Blake, Julie, Michiel, Dennis, Bowser, Brian, Ruppel, Sheryl, Mitra, George, Welch, Anthony, Yovandich, Jason, Salomon, Rachelle, Kean, Leslie, Tarlock, Katherine, Pulsipher, Michael A., Verneris, Michael R, Broglie, Larisa, Fry, Terry J., Devine, Steven M., Aplenc, Richard

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Feasibility, acceptability and effectiveness of integrated care for COPD patients: a mixed methods evaluation of a pilot community-based programme von Carron, Tania, Bridevaux, Pierre-Olivier, Lörvall, Karin, Parmentier, Rachel, Moix, Jean-Bernard, Beytrison, Vincent, Pernet, Raymond, Rey, Constance, Roberfroid, Pierre-Yves, Chhajed, Prashant N, Dieterle, Thomas, Joos Zellweger, Ladina, Kohler, Malcolm, Maier, Sabrina, Miedinger, David, Thurnheer, Robert, Urwyler, Pascal, Tschopp, Jean-Marie, Zuercher, Emilie, Leuppi, Jörg Daniel, Burnand, Bernard, Peytremann-Bridevaux, Isabelle

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De Novo Truncating Variants in ASXL2 Are Associated with a Unique and Recognizable Clinical Phenotype von Pena, Loren D.M., Hempel, Maja, McLaughlin, Heather M., Cho, Megan, Stong, Nicholas, Shuss, Christine M., Burrage, Lindsay C., Dhar, Shweta U., Emrick, Lisa T., Graham, Brett H., Lalani, Seema R., Lewis, Richard A., Posey, Jennifer E., Hanchard, Neil A., Mercedes, Alejandro E., Wangler, Michael F., Muzny, Donna M., Ward, Patricia A., Ramoni, Rachel B., McCray, Alexa T., Mazur, Paul, Splinter, Kimberly, Esteves, Cecilia, Jiang, Yong-hui, Pena, Loren D.M., McConkie-Rosell, Allyn, Schoch, Kelly, Spillmann, Rebecca C., Goldstein, David B., Loscalzo, Joseph, Rodan, Lance H., Walsh, Chris A., Cooper, Cynthia M., Donnell-Fink, Laurel A., Krieg, Elizabeth L., Lincoln, Sharyn A., Worthey, Elizabeth A., Lazar, Joe, Handley, Lori H., Newberry, J. Scott, Schroeder, Molly C., Brown, Donna M., Levy, Shawn E., Dorset, Dan C., Jones, Angela L., Manolio, Teri A., Wise, Anastasia L., Eckstein, David J., Krasnewich, Donna M., Loomis, Carson R., Iglesias, Brenda, Martin, Casey, Koeller, David M., Ashley, Euan A., Zornio, Patricia A., Nelson, Stan F., Palmer, Christina G.S., Allard, Patrick, Dell Angelica, Esteban C., Lee, Hane, Papp, Jeanette C., Dorrani, Naghmeh, Draper, David D., Estwick, Tyra, Gahl, William A., Gartner, Valerie, Godfrey, Rena A., Goheen, Mitchell, Johnston, Jean M., Latham, Lea, Macnamara, Ellen F., Maduro, Valerie V., Malicdan, May V., McCarty, Alexandra J., Murphy, Jennifer L., Novacic, Donna, Pusey, Barbara N., Sadozai, Sarah, Schaffer, Katherine E., Sharma, Prashant, Soldatos, Ariane G., Tifft, Cynthia J., Tolman, Nathanial J., Toro, Camilo, Wahl, Colleen E., Weech, Alec A., Yu, Guoyun, Hamid, Rizwan, Bellet, Jane S., Keels, Martha Ann, El-Dairi, Maysantoine, Stumpel, Constance T.R.M., Klinkenberg, Sylvia, Oberndorff, Karin, Petrovski, Slavé, Kuismin, Outi, Korpi-Heikkilä, Satu, Kurki, Mitja I., Hoischen, Alexander, Goldstein, David B.

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De novo and inherited variants in ZNF292 underlie a neurodevelopmental disorder with features of autism spectrum disorder von Mirzaa, Ghayda M., Chong, Jessica X., Piton, Amélie, Popp, Bernt, Foss, Kimberly, Guo, Hui, Harripaul, Ricardo, Xia, Kun, Scheck, Joshua, Aldinger, Kimberly A., Sajan, Samin A., Tang, Sha, Bonneau, Dominique, Beck, Anita, White, Janson, Mahida, Sonal, Harris, Jacqueline, Smith-Hicks, Constance, Hoyer, Juliane, Zweier, Christiane, Reis, André, Thiel, Christian T., Jamra, Rami Abou, Zeid, Natasha, Yang, Amy, Farach, Laura S., Walsh, Laurence, Payne, Katelyn, Rohena, Luis, Velinov, Milen, Ziegler, Alban, Schaefer, Elise, Gatinois, Vincent, Geneviève, David, Simon, Marleen E.H., Kohler, Jennefer, Rotenberg, Joshua, Wheeler, Patricia, Larson, Austin, Ernst, Michelle E., Akman, Cigdem I., Westman, Rachel, Blanchet, Patricia, Schillaci, Lori-Anne, Vincent-Delorme, Catherine, Gripp, Karen W., Mattioli, Francesca, Guyader, Gwenaël Le, Gerard, Bénédicte, Mathieu-Dramard, Michèle, Morin, Gilles, Sasanfar, Roksana, Ayub, Muhammad, Vasli, Nasim, Yang, Sandra, Person, Rick, Monaghan, Kristin G., Nickerson, Deborah A., van Binsbergen, Ellen, Enns, Gregory M., Dries, Annika M., Rowe, Leah J., Tsai, Anne C.H., Svihovec, Shayna, Friedman, Jennifer, Agha, Zehra, Qamar, Raheel, Rodan, Lance H., Martinez-Agosto, Julian, Ockeloen, Charlotte W., Vincent, Marie, Sunderland, William James, Bernstein, Jonathan A., Eichler, Evan E., Vincent, John B., Bamshad, Michael J.

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Survival protein anoctamin‐6 controls multiple platelet responses including phospholipid scrambling, swelling, and protein cleavage von Mattheij, Nadine J. A., Braun, Attila, Kruchten, Roger, Castoldi, Elisabetta, Pircher, Joachim, Baaten, Constance C. F. M. J., Wülling, Manuela, Kuijpers, Marijke J. E., Köhler, Ralf, Poole, Alastair W., Schreiber, Rainer, Vortkamp, Andrea, Collins, Peter W., Nieswandt, Bernhard, Kunzelmann, Karl, Cosemans, Judith M. E. M, Heemskerk, Johan W. M.

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Feasibility, acceptability and effectiveness of integrated care for COPD patients: a mixed methods evaluation of a pilot community-based programme von Carron, Tania, Bridevaux, Pierre-Olivier, Lörvall, Karin, Parmentier, Rachel, Moix, Jean-Bernard, Beytrison, Vincent, Pernet, Raymond, Rey, Constance, Roberfroid, Pierre-Yves, Chhajed, Prashant N, Dieterle, Thomas, Joos Zellweger, Ladina, Kohler, Malcolm, Maier, Sabrina, Miedinger, David, Thurnheer, Robert, Urwyler, Pascal, Tschopp, Jean-Marie, Zuercher, Emilie, Leuppi, Jörg Daniel, Burnand, Bernard, Peytremann-Bridevaux, Isabelle

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Identification of 4-anilino-3-quinolinecarbonitrile inhibitors of mitogen-activated protein/extracellular signal-regulated kinase 1 kinase von Mallon, Robert, Feldberg, Larry, Kim, Steven, Collins, Karen, Wojciechowicz, Donald, Kohler, Constance, Kovacs, Diana, Discafani, Carolyn, Zhang, Nan, Wu, Biqi, Floyd, Brawner, Powell, Dennis, Berger, Dan

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Point mutations in GLI3 lead to misregulation of its subcellular localization von Krauss, Sybille, So, Joyce, Hambrock, Melanie, Köhler, Andrea, Kunath, Melanie, Scharff, Constance, Wessling, Martina, Grzeschik, Karl-Heinz, Schneider, Rainer, Schweiger, Susann

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Synthesis and Structure–Activity Relationships of 3-Cyano-4-(phenoxyanilino)quinolines as MEK (MAPKK) Inhibitors von Zhang, Nan, Wu, Biqi, Powell, Dennis, Wissner, Allan, B. Floyd, Middleton, D. Kovacs, Eleonora, Toral-Barza, Lourdes, Kohler, Constance

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Synthesis and evaluation of 4-Anilino-6,7-dialkoxy-3-quinolinecarbonitriles as inhibitors of kinases of the Ras-MAPK signaling cascade von Berger, Dan, Dutia, Minu, Powell, Dennis, Wu, Biqi, Wissner, Allan, Boschelli, Diane H., Floyd, M.Brawner, Zhang, Nan, Torres, Nancy, Levin, Jeremy, Du, Xuemei, Wojciechowicz, Donald, Discafani, Carolyn, Kohler, Constance, Kim, Steven C., Feldberg, Larry R., Collins, Karen, Mallon, Robert

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An Enzyme-Linked Immunosorbent Assay for the Raf/MEK1/MAPK Signaling Cascade von Mallon, Robert, Feldberg, Larry R., Kim, Steven C., Collins, Karen, Wojciechowicz, Donald, Hollander, Irwin, Kovacs, Eleanora D., Kohler, Constance

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4-Anilino-3-cyanobenzo[ g]quinolines as Kinase Inhibitors von Zhang, Nan, Wu, Biqi, Wissner, Allan, Powell, Dennis W, Rabindran, Sridhar K, Kohler, Constance, Boschelli, Frank

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Synthesis and evaluation of 4-anilino-6,7-dialkoxy-3-quinolinecarbonitriles as inhibitors of kinases of the Ras-MAPK signaling cascade: Recent advances in the design of kinase inhi... von BERGER, Dan, DUTIA, Minu, XUEMEI DU, WOJCIECHOWICZ, Donald, DISCAFANI, Carolyn, KOHLER, Constance, KIM, Steven C, FELDBERG, Larry R, COLLINS, Karen, MALLON, Robert, POWELL, Dennis, BIQI WU, WISSNER, Allan, BOSCHELLI, Diane H, FLOYD, M. Brawner, NAN ZHANG, TORRES, Nancy, LEVIN, Jeremy

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METHOD FOR TREATMENT OF ENDOTOXIC SHOCK IN A MAMMAL von KOHLER, CONSTANCE, WISSNER, ALLAN, KERWAR, SURESH S

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