Modeling of the Bryostatins to the Phorbol Ester Pharmacophore on Protein Kinase C von Wender, Paul A., Cribbs, Cynthia M., Koehler, Konrad F., Sharkey, Nancy A., Herald, Cherry L., Kamano, Yoshiaki, Pettit, George R., Blumberg, Peter M.

Volltext

Analysis of the Phorbol Ester Pharmacophore on Protein Kinase C as a Guide to the Rational Design of New Classes of Analogs von Wender, Paul A., Koehler, Konrad F., Sharkey, Nancy A., Dell'Aquila, Marie L., Blumberg, Peter M.

Volltext

Synthesis of benzo-fused benzodiazepines employed as probes of the agonist pharmacophore of benzodiazepine receptors von Zhang, Weijiang, Koehler, Konrad F, Harris, Bradford, Skolnick, Phil, Cook, James M

Volltext

Synthetic and computer-assisted analyses of the pharmacophore for the benzodiazepine receptor inverse agonist site von Allen, Michael S, Tan, Yun C, Trudell, Mark L, Narayanan, Kris, Schindler, Liesl R, Martin, Michael J, Schultz, Christopher, Hagen, Timothy J, Koehler, Konrad F

Volltext

Development of subtype-selective oestrogen receptor-based therapeutics von Gustafsson, Jan-Åke, Nilsson, Stefan, Koehler, Konrad F

Volltext

Predictive binding of .beta.-carboline inverse agonists and antagonists via the CoMFA/GOLPE approach von Allen, Michael S, LaLoggia, Anthony J, Dorn, Linda J, Martin, Michael J, Costantino, Gabriele, Hagen, Timothy J, Koehler, Konrad F, Skolnick, Phil, Cook, James M

Volltext

Synthetic and computer assisted analysis of the pharmacophore for agonists at benzodiazepine receptors von Diaz-Arauzo, Hernando, Koehler, Konrad F., Hagen, Timothy J., Cook, James M.

Volltext

Determination of the Structure and Chiroptical Properties of the Parent Nerve Gas O-Methyl Methylphosphonofluoridate by ab Initio Calculations, Electron Diffraction Analysis, and N... von Rauk, A, Shishkov, I. F, Vilkov, L. V, Koehler, K. F, Kostyanovsky, R. G

Volltext

Functional probing of the human glucocorticoid receptor steroid-interacting surface by site-directed mutagenesis. Gln-642 plays an important role in steroid recognition and binding von Lind, U, Greenidge, P, Gillner, M, Koehler, K F, Wright, A, Carlstedt-Duke, J

Volltext

Reflections on the Discovery and Significance of Estrogen Receptor β von Koehler, Konrad F, Helguero, Luisa A, Haldosén, Lars-Arne, Warner, Margaret, Gustafsson, Jan-Åke

Volltext

Synthetic and computer-assisted analysis of the structural requirements for selective, high-affinity ligand binding to diazepam-insensitive benzodiazepine receptors von Wong, Garry, Koehler, Konrad F, Skolnick, Phil, Gu, Zi Qiang, Ananthan, Subramaniam, Schonholzer, Peter, Hunkeler, Walter, Zhang, Weijiang, Cook, James M

Volltext

Genes, autoimmunity and pathogenesis of rheumatic heart disease von Guilherme, L, Köhler, K F, Postol, E, Kalil, J

Volltext

Oestrogen Receptors and Selective Oestrogen Receptor Modulators: Molecular and Cellular Pharmacology von Nilsson, Stefan, Koehler, Konrad F.

Volltext

Molecular yardsticks. Rigid probes to define the spatial dimensions of the benzodiazepine receptor binding site von Martin, Michael J, Trudell, Mark L, Diaz Arauzo, Hernando, Allen, Michael S, LaLoggia, Anthony J, Deng, Li, Schultz, Christopher A, Tan, Yun Chou, Bi, Yingzhi

Volltext

Cycloaddition of nitrones with allenes. An example of steric control of regiochemistry von Padwa, Albert, Kline, Donald N, Koehler, Konrad F, Matzinger, Michael, Venkatramanan, M. K

Volltext

Glucocorticoid Receptor Point Mutation V571M Facilitates Coactivator and Ligand Binding by Structural Rearrangement and Stabilization von Carlsson, Peter, Koehler, Konrad F, Nilsson, Lennart

Volltext

Regioselectivity associated with the 1,3-dipolar cycloaddition of nitrones with electron-deficient dipolarophiles von Padwa, Albert, Fisera, Lubor, Koehler, Konrad F, Rodriguez, Augusto, Wong, George S. K

Volltext

Mouse Estrogen Receptor β Isoforms Exhibit Differences in Ligand Selectivity and Coactivator Recruitment von Zhao, Chunyan, Toresson, Gudrun, Xu, Li, Koehler, Konrad F, Gustafsson, Jan-Åke, Dahlman-Wright, Karin

Volltext

Thyroid Receptor Ligands. 3. Design and Synthesis of 3,5-Dihalo-4-alkoxyphenylalkanoic Acids as Indirect Antagonists of the Thyroid Hormone Receptor von Hedfors, Åsa, Appelqvist, Theresa, Carlsson, Bo, Bladh, Lars-Göran, Litten, Chris, Agback, Peter, Grynfarb, Marlena, Koehler, Konrad F, Malm, Johan

Volltext

New synthesis of .beta.-lactams based on nitrone cycloaddition to nitroalkenes von Padwa, Albert, Koehler, Konrad F, Rodriguez, Augusto

Volltext