Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell ‘stemness’ via the bone morphogenetic protein... von Kodach, Liudmila L, Jacobs, Rutger J, Voorneveld, Philip W, Wildenberg, Manon E, Verspaget, Henricus W, van Wezel, Tom, Morreau, Hans, Hommes, Daniel W, Peppelenbosch, Maikel P, van den Brink, Gijs R, Hardwick, James C H

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ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response von Heijmans, Jarom, van Lidth de Jeude, Jooske F, Koo, Bon-Kyoung, Rosekrans, Sanne L, Wielenga, Mattheus C B, van de Wetering, Marc, Ferrante, Marc, Lee, Amy S, Onderwater, Jos J M, Paton, James C, Paton, Adrienne W, Mommaas, A Mieke, Kodach, Liudmila L, Hardwick, James C, Hommes, Daniël W, Clevers, Hans, Muncan, Vanesa, van den Brink, Gijs R

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Statin Use After Diagnosis of Colon Cancer and Patient Survival von Voorneveld, Philip W., MD, Reimers, Marlies S., MD PhD, Bastiaannet, Esther, PhD, Jacobs, Rutger J., MD, PhD, van Eijk, Ronald, PhD, Zanders, Marjolein M.J., MD, Herings, Ron M.C., PhD, van Herk-Sukel, Myrthe P.P., PhD, Kodach, Liudmila L., MD, PhD, van Wezel, Tom, PhD, Kuppen, Peter J.K., PhD, Morreau, Hans, MD, PhD, van de Velde, Cornelis J.H., MD, PhD, Hardwick, James C.H., MD, PhD, Liefers, Gerrit Jan, MD, PhD

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The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC von Voorneveld, P W, Kodach, L L, Jacobs, R J, van Noesel, C J M, Peppelenbosch, M P, Korkmaz, K S, Molendijk, I, Dekker, E, Morreau, H, van Pelt, G W, Tollenaar, R A E M, Mesker, W, Hawinkels, L J A C, Paauwe, M, Verspaget, H W, Geraets, D T, Hommes, D W, Offerhaus, G J A, van den Brink, G R, ten Dijke, P, Hardwick, J C H

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Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis via Activation of Rho and ROCK von Voorneveld, Philip W, Kodach, Liudmila L, Jacobs, Rutger J, Liv, Nalan, Zonnevylle, A. Christiaan, Hoogenboom, Jacob P, Biemond, Izak, Verspaget, Hein W, Hommes, Daniel W, de Rooij, Karien, van Noesel, Carel J.M, Morreau, Hans, van Wezel, Tom, Offerhaus, G. Johan A, van den Brink, Gijs R, Peppelenbosch, Maikel P, ten Dijke, Peter, Hardwick, James C.H

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The clinical implications of staging laparoscopy in the diagnostic workup of gastric cancer patients: A population based study von van der Sluis, K., Vollebergh, M.A., Kodach, L.L., van Dieren, J.M., de Hingh, I.H.J.T., Wijnhoven, B.P.L., Verhoeven, R.H.A., Sandick, J.W. van

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Karyotype evolution in response to chemoradiotherapy and upon recurrence of esophageal adenocarcinomas von van der Sluis, Karen, van Sandick, Johanna W., Koemans, Willem J., van den Bosch, Tom, Broeks, Annegien, Peters, Dennis, Seignette, Iris M., Rausch, Christian R., van Dijk, Erik, Snaebjornsson, Petur, van den Berg, José G., van Grieken, Nicole C.T., Ylstra, Bauke, Carvalho, Beatriz, Miedema, Daniël M., Kodach, Liudmila L.

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SMAD4 exerts a tumor-promoting role in hepatocellular carcinoma von Hernanda, P Y, Chen, K, Das, A M, Sideras, K, Wang, W, Li, J, Cao, W, Bots, S J A, Kodach, L L, de Man, R A, Ijzermans, J N M, Janssen, H L A, Stubbs, A P, Sprengers, D, Bruno, M J, Metselaar, H J, ten Hagen, T L M, Kwekkeboom, J, Peppelenbosch, M P, Pan, Q

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Gene expression profiles of esophageal squamous cell cancers in Hodgkin lymphoma survivors versus sporadic cases von Ykema, Berbel L M, Hoefnagel, Sanne J M, Rigter, Lisanne S, Kodach, Liudmila L, Meijer, Gerrit A, van Leeuwen, Flora E, Khan, Hina N, Snaebjornsson, Petur, Aleman, Berthe M P, Broeks, Annegien, Meijer, Sybren L, Wang, Kenneth K, Carvalho, Beatriz, Krishnadath, Kausilia K, van Leerdam, Monique E

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Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells von Kodach, Liudmila L., Bos, Carina L., Durán, Nelson, Peppelenbosch, Maikel P., Ferreira, Carmen V., Hardwick, James C.H.

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Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis von Voorneveld, P W, Stache, V, Jacobs, R J, Smolders, E, Sitters, A I, Liesker, A, S Korkmaz, K, Lam, S M, De Miranda, N F C C, Morreau, H, Kodach, L L, Hardwick, J C H

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Role of the 3'-UTR in BMPR2 as a Novel Predisposition Gene for Hereditary Colorectal Polyposis von Peppelenbosch, Maikel P, Kodach, Liudmila L

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Effect of aspirin on the Wnt/β-catenin pathway is mediated via protein phosphatase 2A von Bos, C L, Kodach, L L, van den Brink, G R, Diks, S H, van Santen, M M, Richel, D J, Peppelenbosch, M P, Hardwick, J C H

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Targeting the Myeloid-Derived Suppressor Cell Compartment for Inducing Responsiveness to Immune Checkpoint Blockade Is Best Limited to Specific Subtypes of Gastric Cancers von Kodach, Liudmila L., Peppelenbosch, Maikel P.

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The Bone Morphogenetic Protein Pathway Is Inactivated in the Majority of Sporadic Colorectal Cancers von Kodach, Liudmila L, Wiercinska, Eliza, de Miranda, Noel F.C.C, Bleuming, Sylvia A, Musler, Alex R, Peppelenbosch, Maikel P, Dekker, Evelien, van den Brink, Gijs R, van Noesel, Carel J.M, Morreau, Hans, Hommes, Daniel W, ten Dijke, Peter, Offerhaus, G. Johan A, Hardwick, James C.H

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A Meta-Analysis of SMAD4 Immunohistochemistry as a Prognostic Marker in Colorectal Cancer von Voorneveld, Philip W., MD, Jacobs, Rutger J, Kodach, Liudmila L, Hardwick, James C.H

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Targeted vs Random Biopsies in Surveillance Endoscopy in Hereditary Diffuse Gastric Cancer Syndrome von Van Dieren, Jolanda M., Kodach, Liudmila L., Cats, Annemieke

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Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice von BLEUMING, Sylvia A, HE, Xi C, LINHENG LI, VAN DEN BRINK, Gijs R, KODACH, Liudmila L, HARDWICK, James C, KOOPMAN, Frieda A, TEN KATE, Fiebo J, VAN DEVENTER, Sander J. H, HOMMES, Daniel W, PEPPELENBOSCH, Maikel P, JOHAN OFFERHAUS, G

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High Interobserver Variability Among Pathologists Using Combined Positive Score to Evaluate PD-L1 Expression in Gastric, Gastroesophageal Junction, and Esophageal Adenocarcinoma von Robert, Marie E., Rüschoff, Josef, Jasani, Bharat, Graham, Rondell P., Badve, Sunil S., Rodriguez-Justo, Manuel, Kodach, Liudmila L., Srivastava, Amitabh, Wang, Hanlin L., Tang, Laura H., Troncone, Giancarlo, Rojo, Federico, Van Treeck, Benjamin J., Pratt, James, Shnitsar, Iryna, Kumar, George, Karasarides, Maria, Anders, Robert A.

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The Effect of Statins in Colorectal Cancer Is Mediated Through the Bone Morphogenetic Protein Pathway von Kodach, Liudmila L, Bleuming, Sylvia A, Peppelenbosch, Maikel P, Hommes, Daniel W, van den Brink, Gijs R, Hardwick, James C.H

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