Clinical landscape of LAG-3-targeted therapy von Chocarro, L., Blanco, E., Arasanz, H., Fernández-Rubio, L., Bocanegra, A., Echaide, M., Garnica, M., Ramos, P., Fernández-Hinojal, G., Vera, R., Kochan, G., Escors, D.

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Isoform-specific AKT inhibition differentially affects cell functions in pancreatic adenocarcinoma von Arasanz, H., Gato-Cañas, M., Zuazo, M., Ibáñez-Vea, M., Fernández-Hinojal, G., Fernandez-Irigoyen, J., Santamaria, E., Kochan, G., Vera, R., Escors, D.

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Pre-treatment CD4 senescent T cells accurately predicts lack of response to PD-L1/PD-1 immune checkpoint blockade in non-small cell lung cancer and correlates with risk of hyperpro... von Zuazo, M., Arasanz, H., Gato-Cañas, M., Fernández-Hinojal, G., Hernández-Marín, B., Martínez-Aguillo, M., Ibáñez-Vea, M., Lecumberri Biurrun, M.J., Fernández de Lascoiti, Á, Vera, R., Kochan, G., Escors, D.

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Shell Programming in Unix, Linux and OS X, Fourth Edition von Stephen G. Kochan, Patrick Wood

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Thermolability of mutant MMACHC protein in the vitamin B12-responsive cblC disorder von Froese, D.S., Healy, S., McDonald, M., Kochan, G., Oppermann, U., Niesen, F.H., Gravel, R.A.

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Shell Programming in Unix, Linux and OS X von Kochan, Stephen, Wood, Patrick

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Programming in C von Kochan, Stephen G

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Programming in Objective-C, Third Edition von Stephen G. Kochan

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55P Clinical landscape of LAG-3-targeted therapy von Chocarro, L., Blanco, E., Arasanz, H., Bocanegra, A., Fernández-Rubio, L., Echaide, M., Garnica, M., Ramos, P., Fernández-Hinojal, G., Vera, R., Kochan, G., Escors, D.

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Characterization of the RNA-binding activity of VP3, a major structural protein of Infectious bursal disease virus von KOCHAN, G, GONZALEZ, D, RODRIGUEZ, J. F

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4P CBL-B inhibition overcomes PD-1/LAG-3 mediated resistance in lung cancer von Chocarro, L.D.E., Blanco, E., Fenández-Rubio, L., Garnica, M., Zuazo, M., Granda, M.J. Garcia, Bocanegra, A., Echaide, M., Johnston, C., Edwards, C.J., Legg, J., Pierce, A., Arasanz, H., Fernandez-Hinojal, G., Vera, R., Ausin, K., Santamaría, E., Fernández-Irigoyen, J., Kochan, G., Escors, D.

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24P The STAT3 phosphorylation status discriminates tumor associated populations in myeloid cell tumor-infiltrating model von Palmeiro, E.B., Ibañez, M., Hernández, C., Chocarro, L., Arasanz, H., Bocanegra, A., Fernandez, J., Santamaria, E., Vera, R., Smerdou, C., Escors, D., Kochan, G.

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Programming in Objective-C von Kochan, Stephen

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40P Identification of a PD-1/LAG-3 co-expression profile in human tumor-infiltrating T cells uncovers a T cell dysfunctionality genetic regulated programme von Chocarro, L., Blanco, E., Arasanz, H., Fernández-Rubio, L., Bocanegra, A.I., Echaide, M., Garnica, M., Ramos, P., Piñeiro-Hermida, S., García-Granda, M.J., Vera, R., Santamaría, E., Fernández-Irigoyen, J., Kochan, G., Escors, D.

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17P Engineering and expression of constitutive activators of the PD-1 and LAG-3 signaling pathways von Chocarro, L., García Granda, M.J., Zuazo, M., Arasanz, H., Bocanegra, A., Blanco, E., Hernández Sáez, C., Fernández Hinojal, G., Vera, R., Kochan, G., Escors, D.

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15P CBL E3 ubiquitin ligases are key inhibitory regulators in PD-1/LAG-3 co-signaling in human cancers, targeted through bispecific co-blockade von Chocarro, L., Fernández-Rubio, L., Garcia Granda, M.J., Blanco Palmeiro, E., Bocanegra Gondan, A.I., Echaide, M., Garnica, M., Zuazo, M., Johnston, C., Edwards, C.J., Leggs, J., Pierce, A., Arasanz, H., Vera, R., Ausin, K., Santamaría, E., Fernández-Irigoyen, J., Kochan, G., Escors, D.

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17P PD-1 and LAG-3 immune checkpoints constitutive activators exhibit differential expression phenotypes von Chocarro, L., Palmeiro, E.B., Arasanz, H., Bocanegra, A., Zuazo, M., Echaide, M., Morente, P., Fernández-Rubio, L., Fernández-Hinojal, G., Garnica, M., Ramos, P., García-Granda, M.J., Vera, R., Kochan, G., Escors, D.

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1305P Peripheral low-density neutrophils in the response to immunotherapy in untreated non-small cell lung cancer von Arasanz, H., Gondan, A.I. Bocanegra, Palmeiro, E.B., Zuazo, M., Ruiz, I. Morilla, Martínez-Aguillo, M., Teijeira, L., Fernández-Hinojal, G., Chocarro, L., Sancho, P. Morente, Escors, D., Vera, R., Kochan, G.

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1354P Comparison of different hyperprogressive disease criteria in non-small cell lung cancer patients treated with immunotherapy and correlation with somatic mutations in driver g... von Zuazo, M., Arasanz, H., Chocarro, L., Gondan, A.I. Bocanegra, Martínez-Aguillo, M., Ruiz, I. Morilla, Teijeira, L., Guerrero, D., Nova, L.M., Zudaire, T., Arriola, M., Patiño-Garcia, A., Pío, R., Kochan, G., Escors, D., Vera, R.

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1074P Peripheral low-density neutrophils identify a subset of NSCLC patients with high PD-L1 tumor expression that can benefit from chemo-immunotherapy von Arasanz, H., Bocanegra Gondan, A.I., Teijeira, L., Garnica, M., Morilla Ruiz, I., Chocarro, L., Martínez-Aguillo, M., Ausin, K., Blanco, E., Zuazo, M., Fernandez-Hinojal, G., Echaide, M., Fernández-Rubio, L., Pineiro-Hermida, S., Ramos, P., Fernández-Irigoyen, J., Kochan, G., Vera, R., Escors, D.

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