Evolving importance of kidney disease: from subspecialty to global health burden von Eckardt, Kai-Uwe, Prof, Coresh, Josef, Prof, Devuyst, Olivier, Prof, Johnson, Richard J, Prof, Köttgen, Anna, MD, Levey, Andrew S, Prof, Levin, Adeera, Prof

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Mendelian Randomization as an Approach to Assess Causality Using Observational Data von Sekula, Peggy, Del Greco M, Fabiola, Pattaro, Cristian, Köttgen, Anna

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A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure von Yu, Zhi, Coresh, Josef, Qi, Guanghao, Grams, Morgan, Boerwinkle, Eric, Snieder, Harold, Teumer, Alexander, Pattaro, Cristian, Köttgen, Anna, Chatterjee, Nilanjan, Tin, Adrienne

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Identification of a Urate Transporter, ABCG2, with a Common Functional Polymorphism Causing Gout von Woodward, Owen M., Köttgen, Anna, Coresh, Josef, Boerwinkle, Eric, Guggino, William B., Köttgen, Michael, Burg, Maurice B.

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Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans von Schlosser, Pascal, Li, Yong, Sekula, Peggy, Raffler, Johannes, Grundner-Culemann, Franziska, Pietzner, Maik, Cheng, Yurong, Wuttke, Matthias, Steinbrenner, Inga, Schultheiss, Ulla T., Kotsis, Fruzsina, Kacprowski, Tim, Forer, Lukas, Hausknecht, Birgit, Ekici, Arif B., Nauck, Matthias, Völker, Uwe, Walz, Gerd, Oefner, Peter J., Kronenberg, Florian, Mohney, Robert P., Köttgen, Michael, Suhre, Karsten, Eckardt, Kai-Uwe, Kastenmüller, Gabi, Köttgen, Anna

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Genome-Wide Association Studies in Nephrology Research von Köttgen, Anna, MD, MPH

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Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals von Stanzick, Kira J., Li, Yong, Schlosser, Pascal, Gorski, Mathias, Wuttke, Matthias, Thomas, Laurent F., Rasheed, Humaira, Rowan, Bryce X., Graham, Sarah E., Vanderweff, Brett R., Patil, Snehal B., Robinson-Cohen, Cassiane, Gaziano, John M., O’Donnell, Christopher J., Willer, Cristen J., Hallan, Stein, Åsvold, Bjørn Olav, Gessner, Andre, Hung, Adriana M., Pattaro, Cristian, Köttgen, Anna, Stark, Klaus J., Heid, Iris M., Winkler, Thomas W.

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Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Kidney Injury Molecule 1 (KIM-1) as Predictors of Incident CKD Stage 3: The Atherosclerosis Risk in Communities (ARIC) Study von Bhavsar, Nrupen A., PhD, MPH, Köttgen, Anna, MD, MPH, Coresh, Josef, MD, PhD, Astor, Brad C., PhD, MPH

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SLC17A1/3 transporters mediate renal excretion of Lac-Phe in mice and humans von Li, Veronica L., Xiao, Shuke, Schlosser, Pascal, Scherer, Nora, Wiggenhorn, Amanda L., Spaas, Jan, Tung, Alan Sheng-Hwa, Karoly, Edward D., Köttgen, Anna, Long, Jonathan Z.

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Cardiovascular disease protein biomarkers are associated with kidney function: The Framingham Heart Study von Keshawarz, Amena, Hwang, Shih-Jen, Lee, Gha Young, Yu, Zhi, Yao, Chen, Köttgen, Anna, Levy, Daniel

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Epigenome-wide association studies identify DNA methylation associated with kidney function von Chu, Audrey Y., Tin, Adrienne, Schlosser, Pascal, Ko, Yi-An, Qiu, Chengxiang, Yao, Chen, Joehanes, Roby, Grams, Morgan E., Liang, Liming, Gluck, Caroline A., Liu, Chunyu, Coresh, Josef, Hwang, Shih-Jen, Levy, Daniel, Boerwinkle, Eric, Pankow, James S., Yang, Qiong, Fornage, Myriam, Fox, Caroline S., Susztak, Katalin, Köttgen, Anna

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Wildtype heterogeneity contributes to clonal variability in genome edited cells von Westermann, Lukas, Li, Yong, Göcmen, Burulca, Niedermoser, Matthias, Rhein, Kilian, Jahn, Johannes, Cascante, Isabel, Schöler, Felix, Moser, Niklas, Neubauer, Björn, Hofherr, Alexis, Behrens, Yvonne Lisa, Göhring, Gudrun, Köttgen, Anna, Köttgen, Michael, Busch, Tilman

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The relationship between blood metabolites of the tryptophan pathway and kidney function: a bidirectional Mendelian randomization analysis von Cheng, Yurong, Li, Yong, Benkowitz, Paula, Lamina, Claudia, Köttgen, Anna, Sekula, Peggy

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A Metabolome-Wide Association Study of Kidney Function and Disease in the General Population von Sekula, Peggy, Goek, Oemer-Necmi, Quaye, Lydia, Barrios, Clara, Levey, Andrew S, Römisch-Margl, Werner, Menni, Cristina, Yet, Idil, Gieger, Christian, Inker, Lesley A, Adamski, Jerzy, Gronwald, Wolfram, Illig, Thomas, Dettmer, Katja, Krumsiek, Jan, Oefner, Peter J, Valdes, Ana M, Meisinger, Christa, Coresh, Josef, Spector, Tim D, Mohney, Robert P, Suhre, Karsten, Kastenmüller, Gabi, Köttgen, Anna

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Genome-Wide Association Studies of Metabolite Concentrations (mGWAS): Relevance for Nephrology von Köttgen, Anna, Raffler, Johannes, Sekula, Peggy, Kastenmüller, Gabi

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ABCG transporters and disease von Woodward, Owen M., Köttgen, Anna, Köttgen, Michael

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Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program von Hellwege, Jacklyn N., Velez Edwards, Digna R., Giri, Ayush, Qiu, Chengxiang, Park, Jihwan, Torstenson, Eric S., Keaton, Jacob M., Wilson, O. D., Robinson-Cohen, Cassianne, Chung, Cecilia P., Roumie, Christianne L., Klarin, Derek, Damrauer, Scott M., DuVall, Scott L., Siew, Edward, Akwo, Elvis A., Wuttke, Matthias, Gorski, Mathias, Li, Man, Li, Yong, Gaziano, J. Michael, Wilson, Peter W. F., Tsao, Philip S., O’Donnell, Christopher J., Kovesdy, Csaba P., Pattaro, Cristian, Köttgen, Anna, Susztak, Katalin, Edwards, Todd L., Hung, Adriana M.

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Prevalence and Risk Factors of Thyroid Dysfunction in Older Adults in the Community von Diab, Nermin, Daya, Natalie R., Juraschek, Stephen P., Martin, Seth S., McEvoy, John W., Schultheiß, Ulla T., Köttgen, Anna, Selvin, Elizabeth

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Imputation-powered whole-exome analysis identifies genes associated with kidney function and disease in the UK Biobank von Wuttke, Matthias, König, Eva, Katsara, Maria-Alexandra, Kirsten, Holger, Farahani, Saeed Khomeijani, Teumer, Alexander, Li, Yong, Lang, Martin, Göcmen, Burulca, Pattaro, Cristian, Günzel, Dorothee, Köttgen, Anna, Fuchsberger, Christian

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SLC26A1 is a major determinant of sulfate homeostasis in humans von Pfau, Anja, López-Cayuqueo, Karen I, Scherer, Nora, Wuttke, Matthias, Wernstedt, Annekatrin, González Fassrainer, Daniela, Smith, Desiree Ec, van de Kamp, Jiddeke M, Ziegeler, Katharina, Eckardt, Kai-Uwe, Luft, Friedrich C, Aronson, Peter S, Köttgen, Anna, Jentsch, Thomas J, Knauf, Felix

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