FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer von Tomlinson, DC, Baldo, O, Harnden, P, Knowles, MA

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Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo von Lamont, F R, Tomlinson, D C, Cooper, P A, Shnyder, S D, Chester, J D, Knowles, M A

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Mechanisms of FGFR3 actions in endocrine resistant breast cancer von Tomlinson, D.C., Knowles, M.A., Speirs, V.

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Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type- and mutation-specific manner von di Martino, E, L'Hôte, C G, Kennedy, W, Tomlinson, D C, Knowles, M A

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Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer von Tomlinson, D C, Hurst, C D, Knowles, M A

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Hypoxia regulates FGFR3 expression via HIF-1α and miR-100 and contributes to cell survival in non-muscle invasive bladder cancer von Blick, C, Ramachandran, A, Wigfield, S, McCormick, R, Jubb, A, Buffa, F M, Turley, H, Knowles, M A, Cranston, D, Catto, J, Harris, A L

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PIK3CA mutation spectrum in urothelial carcinoma reflects cell context-dependent signaling and phenotypic outputs von Ross, R L, Askham, J M, Knowles, M A

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AKT1 mutations in bladder cancer: identification of a novel oncogenic mutation that can co-operate with E17K von Askham, J M, Platt, F, Chambers, P A, Snowden, H, Taylor, C F, Knowles, M A

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PIK3CA dependence and sensitivity to therapeutic targeting in urothelial carcinoma von Ross, R L, McPherson, H R, Kettlewell, L, Shnyder, S D, Hurst, C D, Alder, O, Knowles, M A

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Next-generation sequencing identifies germline MRE11A variants as markers of radiotherapy outcomes in muscle-invasive bladder cancer von Teo, M.T.W., Dyrskjøt, L., Nsengimana, J., Buchwald, C., Snowden, H., Morgan, J., Jensen, J.B., Knowles, M.A., Taylor, G., Barrett, J.H., Borre, M., Ørntoft, T.F., Bishop, D.T., Kiltie, A.E.

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Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification von Hurst, C D, Tomlinson, D C, Williams, S V, Platt, F M, Knowles, M A

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Putative tumour suppressor gene necdin is hypermethylated and mutated in human cancer von De Faveri, L E, Hurst, C D, Platt, F M, Taylor, C F, Roulson, J-A, Sanchez-Carbayo, M, Knowles, M A, Chapman, E J

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The genetics of transitional cell carcinoma: progress and potential clinical application von KNOWLES, M. A

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Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16 Rb pathway von Chapman, E J, Hurst, C D, Pitt, E, Chambers, P, Aveyard, J S, Knowles, M A

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Expression of NRG1 and its receptors in human bladder cancer von Forster, J A, Paul, A B, Harnden, P, Knowles, M A

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Somatic mutation of PTEN in bladder carcinoma von Aveyard, J S, Skilleter, A, Habuchi, T, Knowles, M A

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What we could do now: molecular pathology of bladder cancer von Knowles, M A

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Tumor heterogeneity of fibroblast growth factor receptor 3 (FGFR3) mutations in invasive bladder cancer: implications for perioperative anti-FGFR3 treatment von Pouessel, D., Neuzillet, Y., Mertens, L.S., van der Heijden, M.S., de Jong, J., Sanders, J., Peters, D., Leroy, K., Manceau, A., Maille, P., Soyeux, P., Moktefi, A., Semprez, F., Vordos, D., de la Taille, A., Hurst, C.D., Tomlinson, D.C., Harnden, P., Bostrom, P.J., Mirtti, T., Horenblas, S., Loriot, Y., Houédé, N., Chevreau, C., Beuzeboc, P., Shariat, S.F., Sagalowsky, A.I., Ashfaq, R., Burger, M., Jewett, M.A.S., Zlotta, A.R., Broeks, A., Bapat, B., Knowles, M.A., Lotan, Y., van der Kwast, T.H., Culine, S., Allory, Y., van Rhijn, B.W.G.

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Protein shedding in urothelial bladder cancer: prognostic implications of soluble urinary EGFR and EpCAM von Bryan, R T, Regan, H L, Pirrie, S J, Devall, A J, Cheng, K K, Zeegers, M P, James, N D, Knowles, M A, Ward, D G

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DBC1 re-expression alters the expression of multiple components of the plasminogen pathway von Louhelainen, J P, Hurst, C D, Pitt, E, Nishiyama, H, Pickett, H A, Knowles, M A

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