Induced Pluripotent Stem Cell–Derived Cardiomyocytes: Boutique Science or Valuable Arrhythmia Model? von Knollmann, Björn C

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Channel Activity of Cardiac Ryanodine Receptors (RyR2) Determines Potency and Efficacy of Flecainide and R-Propafenone against Arrhythmogenic Calcium Waves in Ventricular Cardiomyo... von Savio-Galimberti, Eleonora, Knollmann, Björn C

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Flecainide Therapy Reduces Exercise-Induced Ventricular Arrhythmias in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia von van der Werf, Christian, MD, Kannankeril, Prince J., MD, MSCI, Sacher, Frederic, MD, Krahn, Andrew D., MD, Viskin, Sami, MD, Leenhardt, Antoine, MD, Shimizu, Wataru, MD, PhD, Sumitomo, Naokata, MD, Fish, Frank A., MD, Bhuiyan, Zahurul A., MD, PhD, Willems, Albert R., MD, PhD, van der Veen, Maurits J., MD, PhD, Watanabe, Hiroshi, MD, PhD, Laborderie, Julien, MD, Haïssaguerre, Michel, MD, Knollmann, Björn C., MD, PhD, Wilde, Arthur A.M., MD, PhD

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Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories von Hwang, Hyun Seok, Kryshtal, Dmytro O, Feaster, T.K, Sánchez-Freire, Verónica, Zhang, Jianhua, Kamp, Timothy J, Hong, Charles C, Wu, Joseph C, Knollmann, Björn C

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Increased myofilament Ca2+ -sensitivity and arrhythmia susceptibility von Huke, Sabine, Knollmann, Björn C

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Assessment of dynamic cardiac repolarization and contractility in patients with hypertrophic cardiomyopathy von Radbill, Andrew E, Lei, Lucy Y, Paranjape, Sachin Y, Blackwell, Daniel J, Abraham, Robert L, Chew, Derek S, Raj, Satish R, Knollmann, Björn C

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Pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes von Nakamura, Kenta, Neidig, Lauren E., Yang, Xiulan, Weber, Gerhard J., El-Nachef, Danny, Tsuchida, Hiroshi, Dupras, Sarah, Kalucki, Faith A., Jayabalu, Anu, Futakuchi-Tsuchida, Akiko, Nakamura, Daisy S., Marchianò, Silvia, Bertero, Alessandro, Robinson, Melissa R., Cain, Kevin, Whittington, Dale, Tian, Rong, Reinecke, Hans, Pabon, Lil, Knollmann, Björn C., Kattman, Steven, Thies, R. Scott, MacLellan, W. Robb, Murry, Charles E.

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Divergent Regulation of Ryanodine Receptor 2 Calcium Release Channels by Arrhythmogenic Human Calmodulin Missense Mutants von Hwang, Hyun Seok, Nitu, Florentin R, Yang, Yi, Walweel, Kafa, Pereira, Laetitia, Johnson, Christopher N, Faggioni, Michela, Chazin, Walter J, Laver, Derek, George, Alfred L, Cornea, Razvan L, Bers, Donald M, Knollmann, Björn C

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RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET von Šeflová, Jaroslava, Schwarz, Jacob A., Smith, Abigail N., Svensson, Bengt, Blackwell, Daniel J., Phillips, Taylor A., Nikolaienko, Roman, Bovo, Elisa, Rebbeck, Robyn T., Zima, Aleksey V., Thomas, David D., Van Petegem, Filip, Knollmann, Björn C., Johnston, Jeffrey N., Robia, Seth L., Cornea, Răzvan L.

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Efficacy and potency of class I antiarrhythmic drugs for suppression of Ca2+ waves in permeabilized myocytes lacking calsequestrin von Galimberti, Eleonora Savio, Knollmann, Björn C

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Myofilament Ca Sensitization Increases Cytosolic Ca Binding Affinity, Alters Intracellular Ca Homeostasis, and Causes Pause-Dependent Ca-Triggered Arrhythmia von Schober, Tilmann, Huke, Sabine, Venkataraman, Raghav, Gryshchenko, Oleksiy, Kryshtal, Dmytro, Hwang, Hyun Seok, Baudenbacher, Franz J, Knollmann, Björn C

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Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass von Hilliard, Fredrick A, Steele, Derek S, Laver, Derek, Yang, Zhaokang, Le Marchand, Sylvain J, Chopra, Nagesh, Piston, David W, Huke, Sabine, Knollmann, Björn C

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New roles of calsequestrin and triadin in cardiac muscle von Knollmann, Björn C.

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A genetic framework for improving arrhythmia therapy von Roden, Dan M, Knollmann, Björn C

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Triadin regulates cardiac muscle couplon structure and microdomain Ca(2+) signalling: a path towards ventricular arrhythmias von Chopra, Nagesh, Knollmann, Björn C

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Calsequestrin 2 and arrhythmias von Faggioni, Michela, Knollmann, Björn C

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Ablation of triadin causes loss of cardiac Ca²⁺ release units, impaired excitation-contraction coupling, and cardiac arrhythmias von Chopra, Nagesh, Yang, Tao, Asghari, Parisa, Moore, Edwin D, Huke, Sabine, Akin, Brandy, Cattolica, Robert A, Perez, Claudio F, Hlaing, Thinn, Knollmann-Ritschel, Barbara E.C, Jones, Larry R, Pessah, Isaac N, Allen, Paul D, Franzini-Armstrong, Clara, Knollmann, Björn C

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Myofilament Ca2+ sensitization causes susceptibility to cardiac arrhythmia in mice von Baudenbacher, Franz, Schober, Tilmann, Pinto, Jose Renato, Sidorov, Veniamin Y, Hilliard, Fredrick, Solaro, R John, Potter, James D, Knollmann, Björn C

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The selective RyR2 inhibitor ent-verticilide suppresses atrial fibrillation susceptibility caused by Pitx2 deficiency von Kim, Kyungsoo, Blackwell, Daniel J., Yuen, Samantha L., Thorpe, Madelaine P., Johnston, Jeffrey N., Cornea, Razvan L., Knollmann, Björn C.

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Calcium in atrial fibrillation - pulling the trigger or not? von Gomez-Hurtado, Nieves, Knollmann, Björn C

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