A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte von Plasschaert, Lindsey W., Žilionis, Rapolas, Choo-Wing, Rayman, Savova, Virginia, Knehr, Judith, Roma, Guglielmo, Klein, Allon M., Jaffe, Aron B.

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An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion von Keller, Caroline Gubser, Shin, Youngah, Monteys, Alex Mas, Renaud, Nicole, Beibel, Martin, Teider, Natalia, Peters, Thomas, Faller, Thomas, St-Cyr, Sophie, Knehr, Judith, Roma, Guglielmo, Reyes, Alejandro, Hild, Marc, Lukashev, Dmitriy, Theil, Diethilde, Dales, Natalie, Cha, Jang-Ho, Borowsky, Beth, Dolmetsch, Ricardo, Davidson, Beverly L., Sivasankaran, Rajeev

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Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis von Wang, Zhong-Yi, Keogh, Adrian, Waldt, Annick, Cuttat, Rachel, Neri, Marilisa, Zhu, Shanshan, Schuierer, Sven, Ruchti, Alexandra, Crochemore, Christophe, Knehr, Judith, Bastien, Julie, Ksiazek, Iwona, Sánchez-Taltavull, Daniel, Ge, Hui, Wu, Jing, Roma, Guglielmo, Helliwell, Stephen B., Stroka, Deborah, Nigsch, Florian

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A comprehensive assessment of RNA-seq protocols for degraded and low-quantity samples von Schuierer, Sven, Carbone, Walter, Knehr, Judith, Petitjean, Virginie, Fernandez, Anita, Sultan, Marc, Roma, Guglielmo

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Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62 von DeJesus, Rowena, Moretti, Francesca, McAllister, Gregory, Wang, Zuncai, Bergman, Phil, Liu, Shanming, Frias, Elizabeth, Alford, John, Reece-Hoyes, John S, Lindeman, Alicia, Kelliher, Jennifer, Russ, Carsten, Knehr, Judith, Carbone, Walter, Beibel, Martin, Roma, Guglielmo, Ng, Aylwin, Tallarico, John A, Porter, Jeffery A, Xavier, Ramnik J, Mickanin, Craig, Murphy, Leon O, Hoffman, Gregory R, Nyfeler, Beat

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Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy von Potting, Christoph, Crochemore, Christophe, Moretti, Francesca, Nigsch, Florian, Schmidt, Isabel, Manneville, Carole, Carbone, Walter, Knehr, Judith, DeJesus, Rowena, Lindeman, Alicia, Maher, Rob, Russ, Carsten, McAllister, Gregory, Reece-Hoyes, John S., Hoffman, Gregory R., Roma, Guglielmo, Müller, Matthias, Sailer, Andreas W., Helliwell, Stephen B.

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PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma von Bleu, Melusine, Gaulis, Swann, Lopes, Rui, Sprouffske, Kathleen, Apfel, Verena, Holwerda, Sjoerd, Pregnolato, Marco, Yildiz, Umut, Cordoʹ, Valentina, Dost, Antonella F. M., Knehr, Judith, Carbone, Walter, Lohmann, Felix, Lin, Charles Y., Bradner, James E., Kauffmann, Audrey, Tordella, Luca, Roma, Guglielmo, Galli, Giorgio G.

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A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi von Voorberg-van der Wel, Annemarie, Roma, Guglielmo, Gupta, Devendra Kumar, Schuierer, Sven, Nigsch, Florian, Carbone, Walter, Zeeman, Anne-Marie, Lee, Boon Heng, Hofman, Sam O, Faber, Bart W, Knehr, Judith, Pasini, Erica, Kinzel, Bernd, Bifani, Pablo, Bonamy, Ghislain M C, Bouwmeester, Tewis, Kocken, Clemens H M, Diagana, Thierry Tidiane

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Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens von Barbosa, Inês A. M., Gopalakrishnan, Rajaraman, Mercan, Samuele, Mourikis, Thanos P., Martin, Typhaine, Wengert, Simon, Sheng, Caibin, Ji, Fei, Lopes, Rui, Knehr, Judith, Altorfer, Marc, Lindeman, Alicia, Russ, Carsten, Naumann, Ulrike, Golji, Javad, Sprouffske, Kathleen, Barys, Louise, Tordella, Luca, Schübeler, Dirk, Schmelzle, Tobias, Galli, Giorgio G.

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IRF2 is a master regulator of human keratinocyte stem cell fate von Mercado, Nicolas, Schutzius, Gabi, Kolter, Christian, Estoppey, David, Bergling, Sebastian, Roma, Guglielmo, Gubser Keller, Caroline, Nigsch, Florian, Salathe, Adrian, Terranova, Remi, Reece-Hoyes, John, Alford, John, Russ, Carsten, Knehr, Judith, Hoepfner, Dominic, Aebi, Alexandra, Ruffner, Heinz, Beck, Tanner C., Jagannathan, Sajjeev, Olson, Calla M., Sheppard, Hadley E., Elsarrag, Selma Z., Bouwmeester, Tewis, Frederiksen, Mathias, Lohmann, Felix, Lin, Charles Y., Kirkland, Susan

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An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells von Kobylarz, Marek J., Goodwin, Jonathan M., Kang, Zhao B., Annand, John W., Hevi, Sarah, O'Mahony, Ellen, McAllister, Gregory, Reece-Hoyes, John, Wang, Qiong, Alford, John, Russ, Carsten, Lindeman, Alicia, Beibel, Martin, Roma, Guglielmo, Carbone, Walter, Knehr, Judith, Loureiro, Joseph, Antczak, Christophe, Wiederschain, Dmitri, Murphy, Leon O., Menon, Suchithra, Nyfeler, Beat

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Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells von Estoppey, David, Hewett, Jeffrey W., Guy, Chantale T., Harrington, Edmund, Thomas, Jason R., Schirle, Markus, Cuttat, Rachel, Waldt, Annick, Gerrits, Bertran, Yang, Zinger, Schuierer, Sven, Pan, Xuewen, Xie, Kevin, Carbone, Walter, Knehr, Judith, Lindeman, Alicia, Russ, Carsten, Frias, Elizabeth, Hoffman, Gregory R., Varadarajan, Malini, Ramadan, Nadire, Reece-Hoyes, John S., Wang, Qiong, Chen, Xin, McAllister, Gregory, Roma, Guglielmo, Bouwmeester, Tewis, Hoepfner, Dominic

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Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma von Ross, Nathan T., Lohmann, Felix, Carbonneau, Seth, Fazal, Aleem, Weihofen, Wilhelm A., Gleim, Scott, Salcius, Michael, Sigoillot, Frederic, Henault, Martin, Carl, Sarah H., Rodríguez-Molina, Juan B., Miller, Howard R., Brittain, Scott M., Murphy, Jason, Zambrowski, Mark, Boynton, Geoffrey, Wang, Yuan, Chen, Aye, Molind, Gregory J., Wilbertz, Johannes H., Artus-Revel, Caroline G., Jia, Min, Akinjiyan, Favour A., Turner, Jonathan, Knehr, Judith, Carbone, Walter, Schuierer, Sven, Reece-Hoyes, John S., Xie, Kevin, Saran, Chitra, Williams, Eric T., Roma, Guglielmo, Spencer, Matt, Jenkins, Jeremy, George, Elizabeth L., Thomas, Jason R., Michaud, Gregory, Schirle, Markus, Tallarico, John, Passmore, Lori A., Chao, Jeffrey A., Beckwith, Rohan E. J.

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Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens von Lopes, Rui, Sprouffske, Kathleen, Sheng, Caibin, Uijttewaal, Esther C. H., Wesdorp, Adriana Emma, Dahinden, Jan, Wengert, Simon, Diaz-Miyar, Juan, Yildiz, Umut, Bleu, Melusine, Apfel, Verena, Mermet-Meillon, Fanny, Krese, Rok, Eder, Mathias, Olsen, Andre Vidas, Hoppe, Philipp, Knehr, Judith, Carbone, Walter, Cuttat, Rachel, Waldt, Annick, Altorfer, Marc, Naumann, Ulrike, Weischenfeldt, Joachim, DeWeck, Antoine, Kauffmann, Audrey, Roma, Guglielmo, Schubeler, Dirk, Galli, Giorgio G.

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STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia von Morozzi, Giulio, Rothen, Julian, Toussaint, Gauthier, De Lange, Katrina, Westritschnig, Katrin, Doelemeyer, Arno, Ueberschlag, Vanessa Pitiot, Kahle, Peter, Lambert, Christian, Obrecht, Michael, Beckmann, Nicolau, Ritter, Veronique, Panesar, Moh, Stauffer, Daniela, Garnier, Isabelle, Mueller, Matthias, Guerini, Danilo, Keller, Caroline Gubser, Knehr, Judith, Roma, Guglielmo, Bidinosti, Michael, Brachat, Sophie, Morvan, Frederic, Fornaro, Mara

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Farnesoid X Receptor Agonism, Acetyl‐Coenzyme A Carboxylase Inhibition, and Back Translation of Clinically Observed Endpoints of De Novo Lipogenesis in a Murine NASH Model von Gapp, Berangere, Jourdain, Marie, Bringer, Pauline, Kueng, Benjamin, Weber, Delphine, Osmont, Arnaud, Zurbruegg, Stefan, Knehr, Judith, Falchetto, Rocco, Roma, Guglielmo, Dietrich, William, Valdez, Reginald, Beckmann, Nicolau, Nigsch, Florian, Sanyal, Arun J., Ksiazek, Iwona

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A Simple and Efficient CRISPR Technique for Protein Tagging von Zeng, Fanning, Beck, Valerie, Schuierer, Sven, Garnier, Isabelle, Manneville, Carole, Agarinis, Claudia, Morelli, Lapo, Quinn, Lisa, Knehr, Judith, Roma, Guglielmo, Bassilana, Frederic, Nash, Mark

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Protein destabilization underlies pathogenic missense mutations in ARID1B von Mermet-Meillon, Fanny, Mercan, Samuele, Bauer-Probst, Beatrice, Allard, Cyril, Bleu, Melusine, Calkins, Keith, Knehr, Judith, Altorfer, Marc, Naumann, Ulrike, Sprouffske, Kathleen, Barys, Louise, Sesterhenn, Fabian, Galli, Giorgio G.

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CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma von Ross, Nathan T., Lohmann, Felix, Carbonneau, Seth, Fazal, Aleem, Weihofen, Wilhelm A., Gleim, Scott, Salcius, Michael, Sigoillot, Frederic, Henault, Martin, Carl, Sarah H., Rodríguez-Molina, Juan B., Miller, Howard R., Brittain, Scott M., Murphy, Jason, Zambrowski, Mark, Boynton, Geoffrey, Wang, Yuan, Chen, Aye, Molind, Gregory J., Wilbertz, Johannes H., Artus-Revel, Caroline G., Jia, Min, Akinjiyan, Favour A., Turner, Jonathan, Knehr, Judith, Carbone, Walter, Schuierer, Sven, Reece-Hoyes, John S., Xie, Kevin, Saran, Chitra, Williams, Eric T., Roma, Guglielmo, Spencer, Matt, Jenkins, Jeremy, George, Elizabeth L., Thomas, Jason R., Michaud, Gregory, Schirle, Markus, Tallarico, John, Passmore, Lori A., Chao, Jeffrey A., Beckwith, Rohan E. J.

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IL-26 Potentiates Type 2 Skin Inflammation in the Presence of IL-1β von Bier, Katharina, Senajova, Zuzana, Henrion, Fanny, Wang, Yichen, Bruno, Sandro, Rauld, Celine, Hörmann, Lisa C., Barske, Carmen, Delucis-Bronn, Corinne, Bergling, Sebastian, Altorfer, Marc, Hägele, Jasmin, Knehr, Judith, Junt, Tobias, Roediger, Ben, Röhn, Till A., Kolbinger, Frank

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