A novel targeted NGS panel identifies numerous homologous recombination deficiency (HRD)-associated gene mutations in addition to known BRCA mutations von Vogel, Anne, Haupts, Anna, Kloth, Michael, Roth, Wilfried, Hartmann, Nils

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Activating ERBB2/HER2 mutations indicate susceptibility to pan-HER inhibitors in Lynch and Lynch-like colorectal cancer von Kloth, Michael, Ruesseler, Vanessa, Engel, Christoph, Koenig, Katharina, Peifer, Martin, Mariotti, Erika, Kuenstlinger, Helen, Florin, Alexandra, Rommerscheidt-Fuss, Ursula, Koitzsch, Ulrike, Wodtke, Claudia, Ueckeroth, Frank, Holzapfel, Stefanie, Aretz, Stefan, Propping, Peter, Loeffler, Markus, Merkelbach-Bruse, Sabine, Odenthal, Margarete, Friedrichs, Nicolaus, Heukamp, Lukas Carl, Zander, Thomas, Buettner, Reinhard

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Decreased mitochondrial transcription factor A and mitochondrial DNA copy number promote cyclin-dependent kinase inhibitor 1A expression and reduce tumorigenic properties of colore... von Buchwaldt, Jessika, Fritsch, Tania, Hartmann, Monika, Witzel, Hagen Roland, Kloth, Michael, Roth, Wilfried, Tagscherer, Katrin E., Hartmann, Nils

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Diffusion kernel-based predictive modeling of KRAS dependency in KRAS wild type cancer cell lines von Ulmer, Bastian, Odenthal, Margarete, Buettner, Reinhard, Roth, Wilfried, Kloth, Michael

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STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor von Kloth, Michael T., Laughlin, Kristen K., Biscardi, Jacqueline S., Boerner, Julie L., Parsons, Sarah J., Silva, Corinne M.

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1033: SURGICAL MANAGEMENT OF COLORECTAL LIVER METASTASES WITH MAJOR VESSEL INVOLVEMENT von Baumgart, Janine, Hiller, Sebastian, Kloth, Michael, Lang, Hauke

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Response to the Comment on “Extended Molecular Profiling Improves Stratification and Prediction of Survival After Resection of Colorectal Liver Metastases” von Lang, Hauke, Kloth, Michael, Moehler, Markus, Roth, Wilfried, Baumgart, Janine

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Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS) von Horpaopan, Sukanya, Kirfel, Jutta, Peters, Sophia, Kloth, Michael, Hüneburg, Robert, Altmüller, Janine, Drichel, Dmitriy, Odenthal, Margarete, Kristiansen, Glen, Strassburg, Christian, Nattermann, Jacob, Hoffmann, Per, Nürnberg, Peter, Büttner, Reinhard, Thiele, Holger, Kahl, Philip, Spier, Isabel, Aretz, Stefan

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Multistain deep learning for prediction of prognosis and therapy response in colorectal cancer von Foersch, Sebastian, Glasner, Christina, Woerl, Ann-Christin, Eckstein, Markus, Wagner, Daniel-Christoph, Schulz, Stefan, Kellers, Franziska, Fernandez, Aurélie, Tserea, Konstantina, Kloth, Michael, Hartmann, Arndt, Heintz, Achim, Weichert, Wilko, Roth, Wilfried, Geppert, Carol, Kather, Jakob Nikolas, Jesinghaus, Moritz

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Novel Activation of STAT5b in Response to Epidermal Growth Factor von Kloth, Michael T., Catling, Andrew D., Silva, Corinne M.

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Extended Molecular Profiling Improves Stratification and Prediction of Survival After Resection of Colorectal Liver Metastases von Lang, Hauke, Baumgart, Janine, Heinrich, Stefan, Tripke, Verena, Passalaqua, Monia, Maderer, Annett, Galle, Peter R, Roth, Wilfried, Kloth, Michael, Moehler, Markus

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Resection of Colorectal Liver Metastases with Major Vessel Involvement von Baumgart, Janine, Hiller, Sebastian, Stroh, Kristina, Kloth, Michael, Lang, Hauke

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Two-Stage Hepatectomy and ALPPS for Advanced Bilateral Liver Metastases: a Tailored Approach Balancing Risk and Outcome von Baumgart, Janine, Jungmann, Florian, Bartsch, Fabian, Kloth, Michael, Mittler, Jens, Heinrich, Stefan, Lang, Hauke

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Exome Sequencing Identifies Biallelic MSH3 Germline Mutations as a Recessive Subtype of Colorectal Adenomatous Polyposis von Adam, Ronja, Spier, Isabel, Zhao, Bixiao, Kloth, Michael, Marquez, Jonathan, Hinrichsen, Inga, Kirfel, Jutta, Tafazzoli, Aylar, Horpaopan, Sukanya, Uhlhaas, Siegfried, Stienen, Dietlinde, Friedrichs, Nicolaus, Altmüller, Janine, Laner, Andreas, Holzapfel, Stefanie, Peters, Sophia, Kayser, Katrin, Thiele, Holger, Holinski-Feder, Elke, Marra, Giancarlo, Kristiansen, Glen, Nöthen, Markus M., Büttner, Reinhard, Möslein, Gabriela, Betz, Regina C., Brieger, Angela, Lifton, Richard P., Aretz, Stefan

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Molecular and Clinical Evidence for an ARMC5 Tumor Syndrome: Concurrent Inactivating Germline and Somatic Mutations Are Associated With Both Primary Macronodular Adrenal Hyperplasi... von Elbelt, Ulf, Trovato, Alessia, Kloth, Michael, Gentz, Enno, Finke, Reinhard, Spranger, Joachim, Galas, David, Weber, Susanne, Wolf, Cristina, König, Katharina, Arlt, Wiebke, Büttner, Reinhard, May, Patrick, Allolio, Bruno, Schneider, Jochen G

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Changing histopathological diagnostics by genome-based tumor classification von Kloth, Michael, Buettner, Reinhard

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Cancer gene related characterization of patterns and point of recurrence after resection of colorectal liver metastases von Lang, Hauke, Baumgart, Janine, Roth, Wilfried, Moehler, Markus, Kloth, Michael

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Gene Expression Profiles of AHNAK2, DCSTAMP, FN1, and TERT Correlate With Mutational Status and Recurrence in Papillary Thyroid Carcinoma von Staubitz‐Vernazza, Julia I., Müller, Celine, Heymans, Antonia, Nedwed, Annekathrin Silvia, Schindeldecker, Mario, Hartmann, Monika, Kloth, Michael, Schad, Arno, Roth, Wilfried, Musholt, Thomas J., Hartmann, Nils

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Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome von Binder, Hans, Hopp, Lydia, Schweiger, Michal R, Hoffmann, Steve, Jühling, Frank, Kerick, Martin, Timmermann, Bernd, Siebert, Susann, Grimm, Christina, Nersisyan, Lilit, Arakelyan, Arsen, Herberg, Maria, Buske, Peter, Loeffler‐Wirth, Henry, Rosolowski, Maciej, Engel, Christoph, Przybilla, Jens, Peifer, Martin, Friedrichs, Nicolaus, Moeslein, Gabriela, Odenthal, Margarete, Hussong, Michelle, Peters, Sophia, Holzapfel, Stefanie, Nattermann, Jacob, Hueneburg, Robert, Schmiegel, Wolff, Royer‐Pokora, Brigitte, Aretz, Stefan, Kloth, Michael, Kloor, Matthias, Buettner, Reinhard, Galle, Jörg, Loeffler, Markus

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Implementation of Amplicon Parallel Sequencing Leads to Improvement of Diagnosis and Therapy of Lung Cancer Patients von König, Katharina, Peifer, Martin, Fassunke, Jana, Ihle, Michaela A., Künstlinger, Helen, Heydt, Carina, Stamm, Katrin, Ueckeroth, Frank, Vollbrecht, Claudia, Bos, Marc, Gardizi, Masyar, Scheffler, Matthias, Nogova, Lucia, Leenders, Frauke, Albus, Kerstin, Meder, Lydia, Becker, Kerstin, Florin, Alexandra, Rommerscheidt-Fuss, Ursula, Altmüller, Janine, Kloth, Michael, Nürnberg, Peter, Henkel, Thomas, Bikár, Sven-Ernö, Sos, Martin L., Geese, William J., Strauss, Lewis, Ko, Yon-Dschun, Gerigk, Ulrich, Odenthal, Margarete, Zander, Thomas, Wolf, Jürgen, Merkelbach-Bruse, Sabine, Buettner, Reinhard, Heukamp, Lukas C.

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