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    Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation von Teumer, Alexander, Chaker, Layal, Groeneweg, Stefan, Li, Yong, Barbieri, Caterina, Traglia, Michela, Ahluwalia, Tarunveer S., Appel, Emil Vincent R., Arking, Dan E., Arnold, Alice, Astrup, Arne, Beekman, Marian, Beilby, John P., Bekaert, Sofie, Boerwinkle, Eric, Brown, Suzanne J., De Buyzere, Marc, Campbell, Purdey J., Ceresini, Graziano, Cerqueira, Charlotte, Cucca, Francesco, Eckardt, Kai-Uwe, Ekici, Arif B., Eriksson, Johan G., Ferrrucci, Luigi, Fiers, Tom, Fiorillo, Edoardo, Ford, Ian, Fox, Caroline S., Fuchsberger, Christian, Gieger, Christian, Gögele, Martin, De Grandi, Alessandro, Greiser, Karin Halina, Hansen, Torben, van Heemst, Diana, Hicks, Andrew A., den Hollander, Wouter, Hui, Jennie, Ikram, M. Arfan, Ittermann, Till, Jensen, Richard A., Jing, Jiaojiao, Jukema, J. Wouter, Kajantie, Eero, Kamatani, Yoichiro, Kasbohm, Elisa, Kiemeney, Lambertus A., Kubo, Michiaki, Lapauw, Bruno, Liewald, David C. M., Lim, Ee Mun, Marina, Michela, Mascalzoni, Deborah, Matsuda, Koichi, Medenwald, Daniel, Meisinger, Christa, Meulenbelt, Ingrid, De Meyer, Tim, Meyer zu Schwabedissen, Henriette E., Mikolajczyk, Rafael, Moed, Matthijs, Netea-Maier, Romana T., Nolte, Ilja M., Okada, Yukinori, Pala, Mauro, Pattaro, Cristian, Pedersen, Oluf, Petersmann, Astrid, Porcu, Eleonora, Postmus, Iris, Pramstaller, Peter P., Ramos, Yolande F. M., Rawal, Rajesh, Redmond, Paul, Richards, J. Brent, Rivadeneira, Fernando, Sala, Cinzia F., Selvin, Elizabeth, Soranzo, Nicole, Sørensen, Thorkild I. A., Spector, Timothy D., Starr, John M., Stott, David J., Taes, Youri, Taliun, Daniel, Tanaka, Toshiko, Thuesen, Betina, Visser, W. Edward, Walsh, John P., Wilson, Scott G., Wolffenbuttel, Bruce H. R., Yang, Qiong, Zheng, Hou-Feng, Cappola, Anne, Peeters, Robin P., Naitza, Silvia, Völzke, Henry, Visser, Theo J., Medici, Marco

    Veröffentlicht in Nature communications

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    The transcriptional landscape of age in human peripheral blood von Peters, Marjolein J., Joehanes, Roby, Pilling, Luke C., Schurmann, Claudia, Conneely, Karen N., Powell, Joseph, Reinmaa, Eva, Sutphin, George L., Zhernakova, Alexandra, Schramm, Katharina, Wilson, Yana A., Kobes, Sayuko, Ramos, Yolande F., Göring, Harald H. H., Fornage, Myriam, Liu, Yongmei, Gharib, Sina A., Stranger, Barbara E., Aviv, Abraham, Levy, Daniel, Murabito, Joanne M., Munson, Peter J., Huan, Tianxiao, Hofman, Albert, Uitterlinden, André G., Rivadeneira, Fernando, van Rooij, Jeroen, Stolk, Lisette, Broer, Linda, Verbiest, Michael M. P. J., Jhamai, Mila, Arp, Pascal, Metspalu, Andres, Milani, Lili, Kasela, Silva, Codd, Veryan, Peters, Annette, Herder, Christian, Waldenberger, Melanie, Roden, Michael, Zeilinger, Sonja, Illig, Thomas, Homuth, Georg, Grabe, Hans-Jörgen, Völzke, Henry, Steil, Leif, Kocher, Thomas, Murray, Anna, Melzer, David, Yaghootkar, Hanieh, Bandinelli, Stefania, Moses, Eric K., Kent, Jack W., Williams-Blangero, Sarah, Westra, Harm-Jan, McRae, Allan F., Smith, Jennifer A., Kardia, Sharon L. R., Hovatta, Iiris, Perola, Markus, Salomaa, Veikko, Henders, Anjali K., Martin, Nicholas G., Smith, Alicia K., Mehta, Divya, Binder, Elisabeth B., Nylocks, K Maria, Kennedy, Elizabeth M., Ding, Jingzhong, Suchy-Dicey, Astrid M., Enquobahrie, Daniel A., Brody, Jennifer, Rotter, Jerome I., Chen, Yii-Der I., Houwing-Duistermaat, Jeanine, Kloppenburg, Margreet, Slagboom, P. Eline, Helmer, Quinta, den Hollander, Wouter, Bean, Shannon, Raj, Towfique, Wang, Qiao Ping, Oyston, Lisa J., Tracy, Russell P., Montgomery, Grant W., Turner, Stephen T., Blangero, John, Meulenbelt, Ingrid, Ressler, Kerry J., Franke, Lude, Kettunen, Johannes, Visscher, Peter M., Neely, G. Gregory, Korstanje, Ron, Hanson, Robert L., Prokisch, Holger, Esko, Tonu, Teumer, Alexander, van Meurs, Joyce B. J., Johnson, Andrew D.

    Veröffentlicht in Nature communications

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    Multi-trait analysis characterizes the genetics of thyroid function and identifies causal associations with clinical implications von Steinbrenner, Inga, Li, Yong, Naito, Tatsuhiko, Marouli, Eirini, Galesloot, Tessel E., Babajide, Oladapo, Andreasen, Laura, Bandinelli, Stefania, Beilby, John P., Brown, Suzanne J., Brumpton, Ben, Cappola, Anne R., Ceresini, Graziano, Chaker, Layal, Concas, Maria Pina, Coutinho de Almeida, Rodrigo, Cucca, Francesco, Kjaergaard, Alisa Devedzic, Echouffo Tcheugui, Justin B., Ellervik, Christina, Eriksson, Johan G., Freudenberg, Jan, Gieger, Christian, Giulianini, Franco, Gögele, Martin, Graham, Sarah E., Grarup, Niels, Gunjača, Ivana, Hansen, Torben, Harding, Barbara N., Harris, Sarah E., Hayward, Caroline, Hui, Jennie, Ittermann, Till, Jukema, J. Wouter, Kanters, Jørgen K., Kiemeney, Lambertus A. L. M., Kloppenburg, Margreet, Langenberg, Claudia, Lapauw, Bruno, Liewald, David C. M., Linneberg, Allan, Lominchar, Jesus V. T., Luan, Jian’an, Martin, Nicholas G., Matana, Antonela, Meitinger, Thomas, Meulenbelt, Ingrid, Mitchell, Braxton D., Møllehave, Line T., Naitza, Silvia, Nauck, Matthias, Nursyifa, Casia, Okada, Yukinori, Onano, Stefano, Papadopoulou, Areti, Palmer, Colin N. A., Pattaro, Cristian, Pedersen, Oluf, Peters, Annette, Pietzner, Maik, Pramstaller, Peter P., Psaty, Bruce M., Punda, Ante, Ray, Debashree, Redmond, Paul, Russ, Tom C., Schultheiss, Ulla T., Selvin, Elizabeth, Siddiqui, Moneeza K., Sidore, Carlo, Spedicati, Beatrice, Srinivasan, Sundararajan, Starr, John M., Stott, David J., Tanaka, Toshiko, Torlak, Vesela, Trompet, Stella, Tuhkanen, Johanna, van den Akker, Erik B., van den Eynde, Tibbert, van Heemst, Diana, Verroken, Charlotte, Visser, W. Edward, Völzke, Henry, Walsh, John P., Wareham, Nicholas J., Weiss, Stefan, Willer, Cristen J., Wilson, Scott G., Yang, Qiong, Zemunik, Tatijana, Zhou, Wei, Zhu, Gu, Zöllner, Sebastian, Smit, Johannes W. A., Peeters, Robin P., Köttgen, Anna, Teumer, Alexander, Medici, Marco

    Veröffentlicht in Nature communications

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    Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals von Dastani, Zari, Hivert, Marie-France, Timpson, Nicholas, Perry, John R B, Yuan, Xin, Scott, Robert A, Henneman, Peter, Heid, Iris M, Kizer, Jorge R, Lyytikäinen, Leo-Pekka, Fuchsberger, Christian, Tanaka, Toshiko, Morris, Andrew P, Small, Kerrin, Isaacs, Aaron, Beekman, Marian, Coassin, Stefan, Lohman, Kurt, Qi, Lu, Kanoni, Stavroula, Pankow, James S, Uh, Hae-Won, Wu, Ying, Bidulescu, Aurelian, Rasmussen-Torvik, Laura J, Greenwood, Celia M T, Ladouceur, Martin, Grimsby, Jonna, Manning, Alisa K, Liu, Ching-Ti, Kooner, Jaspal, Mooser, Vincent E, Vollenweider, Peter, Kapur, Karen A, Chambers, John, Wareham, Nicholas J, Langenberg, Claudia, Frants, Rune, Willems-Vandijk, Ko, Oostra, Ben A, Willems, Sara M, Lamina, Claudia, Winkler, Thomas W, Psaty, Bruce M, Tracy, Russell P, Brody, Jennifer, Chen, Ida, Viikari, Jorma, Kähönen, Mika, Pramstaller, Peter P, Evans, David M, St Pourcain, Beate, Sattar, Naveed, Wood, Andrew R, Bandinelli, Stefania, Carlson, Olga D, Egan, Josephine M, Böhringer, Stefan, van Heemst, Diana, Kedenko, Lyudmyla, Kristiansson, Kati, Nuotio, Marja-Liisa, Loo, Britt-Marie, Harris, Tamara, Garcia, Melissa, Kanaya, Alka, Haun, Margot, Klopp, Norman, Wichmann, H-Erich, Deloukas, Panos, Katsareli, Efi, Couper, David J, Duncan, Bruce B, Kloppenburg, Margreet, Adair, Linda S, Borja, Judith B, Wilson, James G, Musani, Solomon, Guo, Xiuqing, Johnson, Toby, Semple, Robert, Teslovich, Tanya M, Allison, Matthew A, Redline, Susan, Buxbaum, Sarah G, Mohlke, Karen L, Meulenbelt, Ingrid, Ballantyne, Christie M, Dedoussis, George V, Hu, Frank B, Liu, Yongmei, Paulweber, Bernhard, Spector, Timothy D, Slagboom, P Eline, Ferrucci, Luigi, Jula, Antti, Perola, Markus, Raitakari, Olli, Florez, Jose C, Salomaa, Veikko

    Veröffentlicht in PLoS genetics

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    Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels von Carli, Jayne F. Martin, Sun, Qi, Kriebel, Jennifer, Feitosa, Mary F, Hedman, Åsa K., Pers, Tune H., Trompet, Stella, Mangino, Massimo, Kristiansson, Kati, Beekman, Marian, Lyytikäinen, Leo-Pekka, Henneman, Peter, Tanaka, Toshiko, Luan, Jian’an, Pasko, Dorota, Renström, Frida, Willems, Sara M., Mahajan, Anubha, Rose, Lynda M., Liu, Yongmei, Pérusse, Louis, Ju Sung, Yun, Ramos, Yolande F., Amuzu, Antoinette, Barroso, Inês, Blangero, John, Buckley, Brendan M., Böhringer, Stefan, Crosslin, David R., Dale, Caroline E., Dastani, Zari, Deelen, Joris, Delgado, Graciela E., Demirkan, Ayse, Finucane, Francis M., Gieger, Christian, Gustafsson, Stefan, Herder, Christian, Ingelsson, Erik, Ioan-Facsinay, Andreea, Jansson, John-Olov, Jenny, Nancy S., Jørgensen, Torben, Koenig, Wolfgang, Kraft, Peter, Kwekkeboom, Joanneke, Laatikainen, Tiina, Lu, Yingchang, Meisinger, Christa, Morris, Andrew P., Männistö, Satu, Paternoster, Lavinia, Rankinen, Tuomo, Rathmann, Wolfgang, Brent Richards, J, Timpson, Nicholas J., van Heemst, Diana, Uh, Hae-Won, Vohl, Marie-Claude, Walker, Mark, Wichmann, Heinz-Erich, Wood, Andrew R., Zeller, Tanja, Zhang, Yiying, Sørensen, Thorkild I. A., Rao, D. C., Jousilahti, Pekka, Hofman, Albert, Osmond, Clive, Palotie, Aarno, Knekt, Paul B., Perola, Markus, Huupponen, Risto K., Kähönen, Mika, Lehtimäki, Terho, Lorentzon, Mattias, Casas, Juan P., Bandinelli, Stefanie, März, Winfried, Isaacs, Aaron, van Dijk, Ko W., Harris, Tamara B., Allison, Matthew A., Chasman, Daniel I., Ohlsson, Claes, Lind, Lars, Langenberg, Claudia, Ferrucci, Luigi, Frayling, Timothy M., Borecki, Ingrid B., Bergmann, Sven, Vollenweider, Peter, Hansen, Torben, Eline Slagboom, P, Grallert, Harald, Spector, Tim D., Jukema, J.W., Klein, Robert J., Franks, Paul W., Lindgren, Cecilia M.

    Veröffentlicht in Nature communications

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    Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations von Boer, Cindy G., Hatzikotoulas, Konstantinos, Southam, Lorraine, Zhang, Yanfei, Coutinho de Almeida, Rodrigo, Wu, Tian T., Zheng, Jie, Hartley, April, Teder-Laving, Maris, Terao, Chikashi, Zengini, Eleni, Alexiadis, George, Bjornsdottir, Gyda, Gilly, Arthur, Ingvarsson, Thorvaldur, Luetge, Almut, Lund, Sigrun H., Mangino, Massimo, Takuwa, Hiroshi, Thomas, Laurent F., Loughlin, John, Arden, Nigel, Doherty, Michael, Ollier, William E.R., Spector, Tim D., Wallis, Gillian A., Martinsen, Amy E., Fors, Egil Andreas, Hagen, Knut, Nilsen, Kristian Bernhard, Lie, Marie Udnesseter, Børte, Sigrid, Brumpton, Ben, Fritsche, Lars G., Zhou, Wei, Heuch, Ingrid, Storheim, Kjersti, Tyrpenou, Evangelos, Koukakis, Athanasios, Efstathios, Chronopoulos, Nikolaou, Vasileios S., Malizos, Konstantinos, Anastasopoulou, Lydia, Abecasis, Goncalo, Baras, Aris, Cantor, Michael, Coppola, Giovanni, Lotta, Luca A., Shuldiner, Alan, Karalis, Katia, Siminovitch, Katherine, Beechert, Christina, Forsythe, Caitlin, Fuller, Erin D., Gu, Zhenhua, Lattari, Michael, Padilla, Maria Sotiropoulos, Widom, Louis, Wolf, Sarah E., Pradhan, Manasi, Manoochehri, Kia, Bai, Xiaodong, Balasubramanian, Suganthi, Boutkov, Boris, Eom, Gisu, Habegger, Lukas, Hawes, Alicia, Maxwell, Evan K., Orelus, Max, Panea, Razvan, Polanco, Tommy, Salerno, William, Staples, Jeffrey C., Li, Dadong, Sharma, Deepika, Banerjee, Ilanjana, Locke, Adam, Haas, Mary, Akbari, Parsa, Ferreira, Manuel A.R., Jones, Marcus B., Mitnaul, Lyndon J., Babis, George C., Cheung, Jason Pui Yin, Kang, Jae Hee, Lietman, Steven A., Samartzis, Dino, Stefansson, Kari, Uitterlinden, André G., Davey Smith, George, Valdes, Ana M., Tsezou, Aspasia, Cheah, Kathryn S.E., Hveem, Kristian, Wilkinson, J. Mark, Meulenbelt, Ingrid, Lee, Ming Ta Michael, van Meurs, Joyce B.J., Styrkársdóttir, Unnur, Zeggini, Eleftheria

    Veröffentlicht in Cell

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    New genetic loci link adipose and insulin biology to body fat distribution von Ferreira, Teresa, Locke, Adam E., Justice, Anne E., Wu, Joseph M. W., Buchkovich, Martin L., Heard-Costa, Nancy L., Drong, Alexander W., Gustafsson, Stefan, Fall, Tove, Scherag, André, Absher, Devin, Ehret, Georg B., Kleber, Marcus E., Peters, Marjolein J., Albrecht, Eva, Bellis, Claire, Böhringer, Stefan, Böttcher, Yvonne, Clarke, Robert, Eklund, Niina, Erdos, Michael R., Estrada, Karol, Eury, Elodie, Friedrich, Nele, Giedraitis, Vilmantas, Gigante, Bruna, Go, Alan S., Hallmans, Goran, Hassinen, Maija, Hunt, Steven C., Koenig, Wolfgang, Kratzer, Wolfgang, Lindström, Jaana, Merger, Sigrun, Mihailov, Evelin, Mills, Rebecca, Moayyeri, Alireza, Müller-Nurasyid, Martina, Nalls, Michael A., Narisu, Narisu, Nolte, Ilja M., Sanna, Serena, Seufferlein, Thomas, Wennauer, Roman, Choi, Murim, Karpe, Fredrik, Keildson, Sarah, Kiryluk, Krzysztof, Lifton, Richard P., Ma, Baoshan, Nicholson, George, Schadt, Eric E., Scott, Robert A., Westra, Harm-Jan, Beilby, John, Bergman, Richard N., Brown, Morris J., Campbell, Harry, Danesh, John, de Geus, Eco J. C., Ferrannini, Ele, Ferrières, Jean, Haiman, Christopher A., Johansen, Berit, Jousilahti, Pekka, Keinanen-Kiukaanniemi, Sirkka M., Kooperberg, Charles, Kumari, Meena, Matise, Tara C., Möhlenkamp, Stefan, Nelis, Mari, Ong, Ken K., Palmer, Lyle J., Ritchie, Marylyn D., Salomaa, Veikko, Samani, Nilesh J., Saramies, Jouko, Sarzynski, Mark A., Schwarz, Peter E. H., Strauch, Konstantin, Boehm, Bernhard O., Chambers, John C., Grabe, Hans-Jörgen, Hamsten, Anders, Kivimaki, Mika, März, Winfried, Pedersen, Nancy L., Pérusse, Louis, Power, Chris, Rauramaa, Rainer, Rivadeneira, Fernando, Thorsteinsdottir, Unnur, Stumvoll, Michael, Watkins, Hugh, Wichmann, H-Erich, Hunter, David J., Qi, Lu, Speliotes, Elizabeth K., Fox, Caroline S., Barroso, Inês

    Veröffentlicht in Nature (London)

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    Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders von Võsa, Urmo, Stathopoulou, Maria G., de Vries, Paul S., Tanaka, Toshiko, Wu, Ying, Karlsson, Robert, Pool, René, Kemp, John P., Verweij, Niek, Smith, Albert V., Huq, Mahmudul, Deelen, Joris, Alizadeh, Behrooz Z., van der Harst, Pim, Navis, Gerjan, Snieder, Harold, Chasman, Daniel I., Meigs, James, Ligthart, Symen, Bis, Josh, Gross, Myron, Koenig, Wolfgang, Uher, Rudolf, Ward-Caviness, Cavin, Boerwinkle, Eric, Stacey, David, Eriksson, Johan, Lahti, Jari, Schraut, Katharina E., Suktitipat, Bhoom, Nutile, Teresa, Schork, Nicholas, Thiering, Elisabeth, Mahajan, Anubha, Aslibekyan, Stella, Yengo, Loïc, Rajan, Kumar B., Timpson, Nicholas, Huang, Hongyan, Uh, Hae-Won, Yanek, Lisa R., Verbanck, Marie, Magnusson, Patrik K.E., Ballantyne, Christie M., Montgomery, Grant W., Rueedi, Rico, Steri, Maristella, Stott, David J., Felix, Stephan B., Kraft, Peter, Seppälä, Ilkka, Williams, Stephen R., Moed, Matthijs, Langenberg, Claudia, Räikkönen, Katri, Sale, Michele M., Chen, Yii-Der I., James, Alan L., Soranzo, Nicole, Berenson, Gerald S., Liewald, David, Beilby, John, Ryan, Kathleen A., Balkau, Beverly, Paternoster, Lavinia, Kähönen, Mika, Sattar, Naveed, van Heemst, Diana, Gambaro, Giovanni, Ferrucci, Luigi, Karlsson, Magnus, Lind, Lars, Mori, Trevor A., Buckley, Brendan M., de Craen, Anton J.M., Scott, Rodney J., Strachan, David P., Jarvelin, Marjo-Riitta, Jukema, J. Wouter, Hamsten, Anders, Gudnason, Vilmundur, Qi, Lu, März, Winfried, Penninx, Brenda W.J.H., Worrall, Bradford B., Gibson, Greg, Oldehinkel, Albertine J., Murray, Sarah S., Pramstaller, Peter P., Deary, Ian J., Desch, Karl C., Hayward, Caroline, Arnett, Donna K., Jess, Tine, Psaty, Bruce M., Tracy, Russell P., Nolte, Ilja M., Visvikis-Siest, Sophie, Franke, Lude, Franco, Oscar H.


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    Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study von Zeggini, Eleftheria, Panoutsopoulou, Kalliope, Southam, Lorraine, Rayner, Nigel W, Day-Williams, Aaron G, Lopes, Margarida C, Boraska, Vesna, Esko, Tonu, Evangelou, Evangelos, Hoffman, Albert, Houwing-Duistermaat, Jeanine J, Ingvarsson, Thorvaldur, Jonsdottir, Ingileif, Jonnson, Helgi, Kerkhof, Hanneke J, Kloppenburg, Margreet, Bos, Steffan D, Mangino, Massimo, Metrustry, Sarah, Slagboom, P Eline, Thorleifsson, Gudmar, Raine, Emma V A, Ratnayake, Madhushika, Ricketts, Michelle, Beazley, Claude, Blackburn, Hannah, Bumpstead, Suzannah, Elliott, Katherine S, Hunt, Sarah E, Potter, Simon C, Shin, So-Youn, Yadav, Vijay K, Zhai, Guangju, Sherburn, Kate, Dixon, Kate, Arden, Elizabeth, Aslam, Nadim, Battley, Phillippa-kate, Carluke, Ian, Doherty, Sally, Gordon, Andrew, Joseph, John, Keen, Richard, Koller, Nicola C, Mitchell, Sheryl, O'Neill, Fiona, Paling, Ellen, Reed, Mike R, Rivadeneira, Fernando, Swift, Diane, Walker, Kirsten, Watkins, Bridget, Wheeler, Maggie, Birrell, Fraser, Ioannidis, John P A, Meulenbelt, Ingrid, Metspalu, Andres, Rai, Ashok, Salter, Donald, Stefansson, Kari, Stykarsdottir, Unnur, Uitterlinden, André G, van Meurs, Joyce B J, Chapman, Kay, Deloukas, Panos, Ollier, William E R, Wallis, Gillian A, Arden, Nigel, Carr, Andrew, Doherty, Michael, McCaskie, Andrew, Willkinson, J Mark, Ralston, Stuart H, Valdes, Ana M, Spector, Tim D, Loughlin, John

    Veröffentlicht in The Lancet (British edition)

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