P237 HEPATIC INFLAMMATION INCREASES IN CD36 DEFICIENT MICE FED WITH A HIGH-FAT DIET von Sheedfar, F, Oosterveer, M, Moesker, B, Kloosterhuis, N, Runow, K, de Bruin, A, Hofker, M, Koonen, D

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A cargo-specific role for hepatocyte retriever in lipoprotein receptor recycling von Vos, D.Y., Smit, M., Huijkman, N., Kloosterhuis, N., Wolters, K., Kuivenhoven, J.A., Van De Sluis, B.

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GPR146 and HDL metabolism von Zhang, B., Mathada, U. Tharehalli, Loaiza, N., Martinez, L., Huijkman, N., Smit, M., Kloosterhuis, N., Van De Sluis, B., Kuivenhoven, J.A.

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Prevention of atherosclerosis and hepatic steatosis by combined, liver-specific deletion of GPR146 and ANGPTL3 von Mathada, U. Tharehalli, Rimbert, A., Zhang, B., Kloosterhuis, N., Huijkman, N., Smit, M., Gerding, A., Van De Sluis, B., Kuivenhoven, J.A.

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Deficiency of Abca1 and Abcg1 mediated cholesterol efflux pathways in smooth muscle cells enhances vasoconstriction but does not affect atherosclerosis von Halmos, B, La Rose, A M, Groenen, A G, Nakladal, D, Bazioti, V, Koster, M H, Kloosterhuis, N J, Van Buiten, A, Kuipers, F, De Jong, I J, Henning, R H, Westerterp, M

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A novel gene affecting VLDL assembly/secretion von Van Zwol, W., Rimbert, A., Wolters, K., Larsen, L., Huijkman, N., Kloosterhuis, N., Van De Sluis, B., Zimmermann, P., Kuivenhoven, J.A.

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The Parkinson’s Disease Gene Vps35 Regulates Plasma Ldl Cholesterol Levels In A Ccc/Wash-Dependent Manner von Vos, D., Wijers, M., Smit, M., Huijkman, N., Kloosterhuis, N., Wolters, K., Kuivenhoven, J.A., van de Sluis, B.

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Stap1 Deficiency In The Immune System Does Not Regulate Plasma Cholesterol In Ldlr-/- Mice von Velasquez, N. Loaiza, Balder, J.W., Wolters, J.C., Smit, M., Kloosterhuis, N., Svendsen, A.F., van der Sluis, B., Kuivenhoven, J.A.

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ADAM17 up-regulation in renal transplant dysfunction and non-transplant-related renal fibrosis von MULDER, Gemma M, MELENHORST, Wynand B. W. H, CELIE, Johanna W. A. M, KLOOSTERHUIS, Niels J, HILLEBRANDS, Jan-Luuk, PLOEG, Rutger J, SEELEN, Marc A, VISSER, Lydia, DIJK, Marcory C. R. F. Van, GOOR, Harry Van

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A Common Variant In Ccdc93 Decreases Ldl-C And Protects Against Myocardial Infarction By Regulating Endosomal Trafficking Of Ldl-Receptor von Rimbert, A., Dalila, N., Wolters, J., Huijkman, N., Smit, M., Kloosterhuis, N., Riemsma, M., van der Veen, Y., Singla, A., van Dijk, F., Frikke-Schmidt, R., Burtsein, E., Tybjaerg-Hansen, T.H., van de Sluis, B., Kuivenhoven, J.A.

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Hepatocyte-specific glucose-6-phosphatase deficiency disturbs platelet aggregation and decreases blood monocytes upon fasting-induced hypoglycemia von La Rose, Anouk M., Bazioti, Venetia, Hoogerland, Joanne A., Svendsen, Arthur F., Groenen, Anouk G., van Faassen, Martijn, Rutten, Martijn G.S., Kloosterhuis, Niels J., Dethmers-Ausema, Bertien, Nijland, J. Hendrik, Mithieux, Gilles, Rajas, Fabienne, Kuipers, Folkert, Lukens, Michaël V., Soehnlein, Oliver, Oosterveer, Maaike H., Westerterp, Marit

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The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model von Kakkar, V, Månsson, C, de Mattos, EP, Bergink, S, van der Zwaag, M, van Waarde, MAWH, Kloosterhuis, NJ, Melki, R, van Cruchten, RTP, Al-Karadaghi, S, Arosio, P, Dobson, CM, Knowles, TPJ, Bates, GP, van Deursen, JM, Linse, S, van de Sluis, B, Emanuelsson, C, Kampinga, HH

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Cargo-Specific Role for Retriever Subunit VPS26C in Hepatocyte Lipoprotein Receptor Recycling to Control Postprandial Triglyceride-Rich Lipoproteins von Vos, Dyonne Y., Wijers, Melinde, Smit, Marieke, Huijkman, Nicolette, Kloosterhuis, Niels J., Wolters, Justina C., Tissink, Joël J., Pronk, Amanda C.M., Kooijman, Sander, Rensen, Patrick C.N., Kuivenhoven, Jan Albert, van de Sluis, Bart

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Tumor necrosis factor receptor 1 gain‐of‐function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model von Aparicio‐Vergara, Marcela, Hommelberg, Pascal P.H., Schreurs, Marijke, Gruben, Nanda, Stienstra, Rinke, Shiri‐Sverdlov, Ronit, Kloosterhuis, Niels J., de Bruin, Alain, van de Sluis, Bart, Koonen, Debby P.Y., Hofker, Marten H.

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The endosomal sorting protein VPS35 controls lipid homeostasis through regulating hepatic lysosomal function von Vos, D.Y., Heida, A., Koster, M., Tissink, J., Kuentzel, K.B., Kloosterhuis, N.J., Smit, M., Huijkman, N., Reggiori, F., Mari, M., Scheja, L., Heeren, J., Kratky, D., Kuivenhoven, J., Van De Sluis, B.

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A novel role for GALNAC-T2 dependent glycosylation in energy homeostasis von Verzijl, C., Oldoni, F., Loaiza, N., Wolters, J.C., Rimbert, A., Struik, D., Smit, M., Kloosterhuis, N.J., Fernandez, A.J., Samara, N.L., E, T., Ten Hagen, K., Tabak, L.A., Jonker, J.W., Kuivenhoven, J.

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Hepatic SMLR1 ablation fully protects against diet-induced atherosclerosis but causes hepatosteatosis via reduced VLDL secretion von Van Zwol, W., Rimbert, A., Wolters, J.C., Bloks, V., Kloosterhuis, N.J., Huijkman, N., Smit, M., Heeren, J., Scheja, L., Bournez, C.T., Kuipers, J., Rajan, S., Hussain, M., Zimmerman, P., Van De Sluis, B., Kuivenhoven, J.

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Raising AWaRe-ness of Antimicrobial Stewardship Challenges in Pediatric Emergency Care: Results from the PERFORM Study Assessing Consistency and Appropriateness of Antibiotic Presc... von Kolberg, Laura, Khanijau, Aakash, van der Velden, Fabian J S, Herberg, Jethro, De, Tisham, Galassini, Rachel, Cunnington, Aubrey J, Wright, Victoria J, Shah, Priyen, Kaforou, Myrsini, Wilson, Clare, Kuijpers, Taco, Martinón-Torres, Federico, Rivero-Calle, Irene, Moll, Henriette, Vermont, Clementien, Pokorn, Marko, Kolnik, Mojca, Pollard, Andrew J, Agyeman, Philipp K A, Schlapbach, Luregn J, Tsolia, Maria N, Yeung, Shunmay, Zavadska, Dace, Zenz, Werner, Schweintzger, Nina A, van der Flier, Michiel, de Groot, Ronald, Usuf, Effua, Voice, Marie, Calvo-Bado, Leonides, Mallet, François, Fidler, Katy, Levin, Michael, Carrol, Enitan D, Emonts, Marieke, von Both, Ulrich

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Heparin binding epidermal growth factor in renal ischaemia/reperfusion injury von Mulder, Gemma M, Nijboer, Willemijn N, Seelen, Marc A, Sandovici, Maria, Bos, Eelke M, Melenhorst, Wynand BWH, Trzpis, Monika, Kloosterhuis, Niels J, Visser, Lydia, Henning, Rob H, Leuvenink, Henri GD, Ploeg, Rutger J, Sunnarborg, Susan W, van Goor, Harry

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Cargo-specific role for retriever subunit VPS26C in hepatocyte lipoprotein receptor recycling to control postprandial triglyceride-rich lipoproteins von Vos, D.Y., Wijers, M., Smit, M., Huijkman, N., Kloosterhuis, N.J., Wolters, J.C., Tissink, J.J., Pronk, A.C.M., Kooijman, S., Rensen, P.C.N., Kuivenhoven, J.A., Sluis, B. van de

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