Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration von Metcalfe, Ciara, Kljavin, Noelyn M., Ybarra, Ryan, de Sauvage, Frederic J.

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Oncogenic ERBB3 Mutations in Human Cancers von Jaiswal, Bijay S., Kljavin, Noelyn M., Stawiski, Eric W., Chan, Emily, Parikh, Chaitali, Durinck, Steffen, Chaudhuri, Subhra, Pujara, Kanan, Guillory, Joseph, Edgar, Kyle A., Janakiraman, Vasantharajan, Scholz, Rolf-Peter, Bowman, Krista K., Lorenzo, Maria, Li, Hong, Wu, Jiansheng, Yuan, Wenlin, Peters, Brock A., Kan, Zhengyan, Stinson, Jeremy, Mak, Michelle, Modrusan, Zora, Eigenbrot, Charles, Firestein, Ron, Stern, Howard M., Rajalingam, Krishnaraj, Schaefer, Gabriele, Merchant, Mark A., Sliwkowski, Mark X., de Sauvage, Frederic J., Seshagiri, Somasekar

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Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21 von Dunshee, Diana Ronai, Bainbridge, Travis W., Kljavin, Noelyn M., Zavala-Solorio, Jose, Schroeder, Amy C., Chan, Ruby, Corpuz, Racquel, Wong, Manda, Zhou, Wei, Deshmukh, Gauri, Ly, Justin, Sutherlin, Daniel P., Ernst, James A., Sonoda, Junichiro

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Homeostatic IL-23 receptor signaling limits Th17 response through IL-22–mediated containment of commensal microbiota von Shih, Vincent Feng-Sheng, Cox, Jennifer, Kljavin, Noelyn M., Dengler, Hart S., Reichelt, Mike, Kumar, Pawan, Rangell, Linda, Kolls, Jay K., Diehl, Lauri, Ouyang, Wenjun, Ghilardi, Nico

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Comparative Oncogenomics Identifies PSMB4 and SHMT2 as Potential Cancer Driver Genes von LEE, Genee Y, HAVERTY, Peter M, DAVIS, David, STOKOE, David, SETTLEMAN, Jeffrey, DE SAUVAGE, Frederic J, NEVE, Richard M, LI LI, KLJAVIN, Noelyn M, BOURGON, Richard, LEE, James, STERN, Howard, MODRUSAN, Zora, SESHAGIRI, Somasekar, ZEMIN ZHANG

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Disruption of PH–kinase domain interactions leads to oncogenic activation of AKT in human cancers von Parikh, Chaitali, Janakiraman, Vasantharajan, Wu, Wen-I, Foo, Catherine K, Kljavin, Noelyn M, Chaudhuri, Subhra, Stawiski, Eric, Lee, Brian, Lin, Jie, Li, Hong, Lorenzo, Maria N, Yuan, Wenlin, Guillory, Joseph, Jackson, Marlena, Rondon, Jesus, Franke, Yvonne, Bowman, Krista K, Sagolla, Meredith, Stinson, Jeremy, Wu, Thomas D, Wu, Jiansheng, Stokoe, David, Stern, Howard M, Brandhuber, Barbara J, Lin, Kui, Skelton, Nicholas J, Seshagiri, Somasekar

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Combined targeting of BRAF and CRAF or BRAF and PI3K effector pathways is required for efficacy in NRAS mutant tumors von Jaiswal, Bijay S, Janakiraman, Vasantharajan, Kljavin, Noelyn M, Eastham-Anderson, Jeffrey, Cupp, James E, Liang, Yuxin, Davis, David P, Hoeflich, Klaus P, Seshagiri, Somasekar

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Antibody-Drug Conjugates for the Treatment of Non-Hodgkin's Lymphoma: Target and Linker-Drug Selection von POLSON, Andrew G, CALEMINE-FENAUX, Jill, FRANTZ, Gretchen, FUJI, Reina N, GRAY, Alane, HARDEN, Kristin, INGLE, Gladys S, KLJAVIN, Noelyn M, KOEPPEN, Hartmut, NELSON, Christopher, PRABHU, Saileta, RAAB, Helga, CHAN, Pamela, ROSS, Sarajane, STEPHAN, Jean-Philippe, SCALES, Suzie J, SPENCER, Susan D, VANDLEN, Richard, WRANIK, Bernd, YU, Shang-Fan, BING ZHENG, EBENS, Allen, CHANG, Wesley, CHRISTENSEN, Erin, CLARK, Suzanna, DE SAUVAGE, Frederic J, EATON, Dan, ELKINS, Kristi, ELLIOTT, J. Michael

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S100a4 upregulation in Pik3caH1047R;Trp53R270H;MMTV-Cre-driven mammary tumors promotes metastasis von Yuan, Wenlin, Goldstein, Leonard D, Durinck, Steffen, Chen, Ying-Jiun, Nguyen, Thong T, Kljavin, Noelyn M, Sokol, Ethan S, Stawiski, Eric W, Haley, Benjamin, Ziai, James, Modrusan, Zora, Seshagiri, Somasekar

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A requirement for wild-type Ras isoforms in mutant KRas-driven signalling and transformation von Bentley, Carolyn, Jurinka, Stefanie S, Kljavin, Noelyn M, Vartanian, Steffan, Ramani, Sree R, Gonzalez, Lino C, Yu, Kebing, Modrusan, Zora, Du, Pan, Bourgon, Richard, Neve, Richard M, Stokoe, David

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IL-27 promotes T cell-dependent colitis through multiple mechanisms von Cox, Jennifer H, Kljavin, Noelyn M, Ramamoorthi, Nandhini, Diehl, Lauri, Batten, Marcel, Ghilardi, Nico

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Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells von Kljavin, Noelyn M, Lucas, Sophie, de Sauvage, Frederic J, Yi, Sothy, Batten, Marcel, Ghilardi, Nico, Danilenko, Dimitry M, Li, Ji, Lee, James

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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations von Pahuja, Kanika Bajaj, Nguyen, Thong T., Jaiswal, Bijay S., Prabhash, Kumar, Thaker, Tarjani M., Senger, Kate, Chaudhuri, Subhra, Kljavin, Noelyn M., Antony, Aju, Phalke, Sameer, Kumar, Prasanna, Mravic, Marco, Stawiski, Eric W., Vargas, Derek, Durinck, Steffen, Gupta, Ravi, Khanna-Gupta, Arati, Trabucco, Sally E., Sokol, Ethan S., Hartmaier, Ryan J., Singh, Ashish, Chougule, Anuradha, Trivedi, Vaishakhi, Dutt, Amit, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Ziai, James, Banavali, Sripad D., Ramprasad, Vedam, DeGrado, William F., Bueno, Raphael, Jura, Natalia, Seshagiri, Somasekar

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CRIg: A Macrophage Complement Receptor Required for Phagocytosis of Circulating Pathogens von Helmy, Karim Y., Katschke, Kenneth J., Gorgani, Nick N., Kljavin, Noelyn M., Elliott, J. Michael, Diehl, Lauri, Scales, Suzie J., Ghilardi, Nico, van Lookeren Campagne, Menno

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Stem cell plasticity enables hair regeneration following Lgr5+ cell loss von Hoeck, Joerg D., Biehs, Brian, Kurtova, Antonina V., Kljavin, Noelyn M., de Sousa e Melo, Felipe, Alicke, Bruno, Koeppen, Hartmut, Modrusan, Zora, Piskol, Robert, de Sauvage, Frederic J.

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Cutting Edge: IL-27 Is a Potent Inducer of IL-10 but Not FoxP3 in Murine T Cells von Batten, Marcel, Kljavin, Noelyn M, Li, Ji, Walter, Michael J, de Sauvage, Frederic J, Ghilardi, Nico

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IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells von Batten, Marcel, Ramamoorthi, Nandhini, Kljavin, Noelyn M, Ma, Cindy S, Cox, Jennifer H, Dengler, Hart S, Danilenko, Dimitry M, Caplazi, Patrick, Wong, Melanie, Fulcher, David A, Cook, Matthew C, King, Cecile, Tangye, Stuart G, de Sauvage, Frederic J, Ghilardi, Nico

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CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens von Helmy, Karim Y, Katschke, Jr, Kenneth J, Gorgani, Nick N, Kljavin, Noelyn M, Elliott, J Michael, Diehl, Lauri, Scales, Suzie J, Ghilardi, Nico, van Lookeren Campagne, Menno

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Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP) von Bainbridge, Travis W., Dunshee, Diana Ronai, Kljavin, Noelyn M., Skelton, Nicholas J., Sonoda, Junichiro, Ernst, James A.

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The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors von Hagenbeek, Thijs J, Webster, Joshua D, Kljavin, Noelyn M, Chang, Matthew T, Pham, Trang, Lee, Ho-June, Klijn, Christiaan, Cai, Allen G, Totpal, Klara, Ravishankar, Buvana, Yang, Naiying, Lee, Da-Hye, Walsh, Kevin B, Hatzivassiliou, Georgia, de la Cruz, Cecile C, Gould, Stephen E, Wu, Xiumin, Lee, Wyne P, Yang, Shuqun, Zhang, Zhixiang, Gu, Qingyang, Ji, Qunsheng, Jackson, Erica L, Lim, Dae-Sik, Dey, Anwesha

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