Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic... von Klisovic, M I, Maghraby, E A, Parthun, M R, Guimond, M, Sklenar, A R, Whitman, S P, Chan, K K, Murphy, T, Anon, J, Archer, K J, Rush, L J, Plass, C, Grever, M R, Byrd, J C, Marcucci, G

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Phase I Study of Oblimersen Sodium, an Antisense to Bcl-2, in Untreated Older Patients With Acute Myeloid Leukemia: Pharmacokinetics, Pharmacodynamics, and Clinical Activity von MARCUCCI, Guide, STOCK, Wendy, MORAN, Mollie, MAHARRY, Kati, NOVICK, Steven, BLOOMFIELD, Clara D, ZWIEBEL, James A, LARSON, Richard A, GREVER, Michael R, CHAN, Kenneth K, BYRD, John C, GUOWEI DAI, KLISOVIC, Rebecca B, SHUJUN LIU, KLISOVIC, Marko I, BLUM, William, KEFAUVER, Cheryl, SHER, Dorie A, GREEN, Margaret

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The MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapy von Whitman, Susan P., Liu, Shujun, Vukosavljevic, Tamara, Rush, Laura J., Yu, Li, Liu, Chunhui, Klisovic, Marko I., Maharry, Kati, Guimond, Martin, Strout, Matthew P., Becknell, Brian, Dorrance, Adrienne, Klisovic, Rebecca B., Plass, Christoph, Bloomfield, Clara D., Marcucci, Guido, Caligiuri, Michael A.

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G3139, a BCL-2 antisense oligo-nucleotide, in AML von Marcucci, G, Stock, W, Dai, G, Klisovic, M I, Maharry, K, Shen, T, Liu, S, Sher, D A, Lucas, D, Zwiebel, A, Larson, R A, Caligiuri, M A, Bloomfield, C D, Chan, K K, Grever, M R, Byrd, J C

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Chipping away at the chip bias: RNA degradation in microarray analysis von Auer, Herbert, Lyianarachchi, Sandya, Newsom, David, Klisovic, Marko I, Marcucci, uido, Kornacker, Karl

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Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia von SHUJUN LIU, TIANSHENG SHEN, VUKOSAVLJEVIC, Tamara, WHITMAN, Susan P, CHANG, Kun-Sang, BYRD, John C, PERROTTI, Danilo, PLASS, Christoph, MARCUCCI, Guido, LENGUYEN HUYNH, KLISOVIC, Marko I, RUSH, Laura J, FORD, Jamie L, JIANHUA YU, BECKNELL, Brian, YU LI, CHUNHUI LIU

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Phase 1 and pharmacodynamic studies of G3139, a Bcl-2 antisense oligonucleotide, in combination with chemotherapy in refractory or relapsed acute leukemia von Marcucci, Guido, Byrd, John C., Dai, Guowei, Klisovic, Marko I., Kourlas, Peter J., Young, Donn C., Cataland, Spero R., Fisher, Diane B., Lucas, David, Chan, Kenneth K., Porcu, Pierluigi, Lin, Zhong-Pin, Farag, Sherif F., Frankel, Stanley R., Zwiebel, James A., Kraut, Eric H., Balcerzak, Stanley P., Bloomfield, Clara D., Grever, Michael R., Caligiuri, Michael A.

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Depsipeptide (FR901228) Inhibits Proliferation and Induces Apoptosis in Primary and Metastatic Human Uveal Melanoma Cell Lines von Klisovic, Dino D, Katz, Steven E, Effron, David, Klisovic, Marko I, Wickham, Joseph, Parthun, Mark R, Guimond, Martin, Marcucci, Guido

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Differential expression of histone post-translational modifications in acute myeloid and chronic lymphocytic leukemia determined by high-pressure liquid chromatography and mass spe... von Zhang, Liwen, Freitas, Michael A, Wickham, Joseph, Parthun, Mark R, Klisovic, Marko I, Marcucci, Guido, Byrd, John C

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Depsipeptide inhibits migration of primary and metastatic uveal melanoma cell lines in vitro: a potential strategy for uveal melanoma von Klisovic, Dino D, Klisovic, Marko I, Effron, David, Liu, Shujun, Marcucci, Guido, Katz, Steven E

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Promotes Gene Expression by Disrupting the DNA Binding of the AML1/ETO and HDAC1 Repressor Complex von Liu, Shujun, Klisovic, M.I., Shen, T., Yu, J., Dai, G., Huynh, L., Vukosavljevic, T., Whitman, S., Perrotti, D., Marcucci, G.

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Erratum: Chipping away at the chip bias: RNA degradation in microarray analysis von Auer, H, Lyianarachchi, S, Newsom, D, Klisovic, M I, Marcucci, G, Kornacker, K

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Intracellular Levels of Oblimersen Sodium and Target Downregulation Correlates to Clinical Activity of bcl-2 Antisense in Acute Myeoid Leukemia (AML) von Marcucci, Guido, Stock, W., Dai, G., Liu, S., Klisovic, R., Klisovic, M.I., Sher, D., Huynh, L., Frankel, S., Blum, W., Larson, R.A., Grever, M.R., Byrd, J.C., Chan, K.K.

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Differential expression of histone post-translational modifications in acute myeloid and chronic lymphocytic leukemia determined by high-pressure liquid chromatography and mass spe... von Zhang, L

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Clinical response and miR-29b predictive significance in older AML patients treated with a 10-day schedule of decitabine von Blum, William, Garzon, Ramiro, Klisovic, Rebecca B, Schwind, Sebastian, Walker, Alison, Geyer, Susan, Liu, Shujun, Havelange, Violaine, Becker, Heiko, Schaaf, Larry, Mickle, Jon, Devine, Hollie, Kefauver, Cheryl, Devine, Steven M, Chan, Kenneth K, Heerema, Nyla A, Bloomfield, Clara D, Grever, Michael R, Byrd, John C, Villalona-Calero, Miguel, Croce, Carlo M, Marcucci, Guido

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Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation von Stone, Richard M, Mandrekar, Sumithra J, Sanford, Ben L, Laumann, Kristina, Geyer, Susan, Bloomfield, Clara D, Thiede, Christian, Prior, Thomas W, Döhner, Konstanze, Marcucci, Guido, Lo-Coco, Francesco, Klisovic, Rebecca B, Wei, Andrew, Sierra, Jorge, Sanz, Miguel A, Brandwein, Joseph M, de Witte, Theo, Niederwieser, Dietger, Appelbaum, Frederick R, Medeiros, Bruno C, Tallman, Martin S, Krauter, Jürgen, Schlenk, Richard F, Ganser, Arnold, Serve, Hubert, Ehninger, Gerhard, Amadori, Sergio, Larson, Richard A, Döhner, Hartmut

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A Phase I Biological Study of MG98, an Oligodeoxynucleotide Antisense to DNA Methyltransferase 1, in Patients with High-Risk Myelodysplasia and Acute Myeloid Leukemia von KLISOVIC, Rebecca B, STOCK, Wendy, VAN LAAR, Emily, CULLEN, Michael, MACLEOD, A. Robert, BESTERMAN, Jeffrey M, REID, Gregory K, BYRD, John C, MARCUCCI, Guido, CATALAND, Spero, KLISOVIC, Marko I, SHUJUN LIU, BLUM, William, GREEN, Margaret, ODENIKE, Olatoyosi, GODLEY, Lucy, VANDEN BURGT, Jennifer

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Impact of NPM1/FLT3-ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia von Döhner, Konstanze, Thiede, Christian, Jahn, Nikolaus, Panina, Ekaterina, Gambietz, Agnes, Larson, Richard A., Prior, Thomas W., Marcucci, Guido, Jones, Dan, Krauter, Jürgen, Heuser, Michael, Voso, Maria Teresa, Ottone, Tiziana, Nomdedeu, Josep F., Mandrekar, Sumithra J., Klisovic, Rebecca B., Wei, Andrew H., Sierra, Jorge, Sanz, Miguel A., Brandwein, Joseph M., de Witte, Theo, Jansen, Joop H., Niederwieser, Dietger, Appelbaum, Frederick R., Medeiros, Bruno C., Tallman, Martin S., Schlenk, Richard F., Ganser, Arnold, Serve, Hubert, Ehninger, Gerhard, Amadori, Sergio, Gathmann, Insa, Benner, Axel, Pallaud, Celine, Stone, Richard M., Döhner, Hartmut, Bloomfield, Clara D.

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Maintenance therapy with decitabine in younger adults with acute myeloid leukemia in first remission: a phase 2 Cancer and Leukemia Group B Study (CALGB 10503) von Blum, W, Sanford, B L, Klisovic, R, DeAngelo, D J, Uy, G, Powell, B L, Stock, W, Baer, M R, Kolitz, J E, Wang, E S, Hoke, E, Mrózek, K, Kohlschmidt, J, Bloomfield, C D, Geyer, S, Marcucci, G, Stone, R M, Larson, R A

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SWOG 1318: A Phase II Trial of Blinatumomab Followed by POMP Maintenance in Older Patients With Newly Diagnosed Philadelphia Chromosome–Negative B-Cell Acute Lymphoblastic Leukemia... von Advani, Anjali S, Moseley, Anna, O'Dwyer, Kristen M, Wood, Brent L, Fang, Min, Wieduwilt, Matthew J, Aldoss, Ibrahim, Park, Jae H, Klisovic, Rebecca B, Baer, Maria R, Stock, Wendy, Bhave, Rupali R, Othus, Megan, Harvey, Richard C, Willman, Cheryl L, Litzow, Mark R, Stone, Richard M, Sharon, Elad, Erba, Harry P

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