Divergent Role of Sphingosine 1-Phosphate in Liver Health and Disease von Kleuser, Burkhard

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Epigenetic histone modulation contributes to improvements in inflammatory bowel disease via EBI3 von Wetzel, Alexandra, Scholtka, Bettina, Gerecke, Christian, Kleuser, Burkhard

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The sphingosine kinase 2 inhibitors ABC294640 and K145 elevate (dihydro)sphingosine 1-phosphate levels in various cells von Prell, Agata, Wigger, Dominik, Huwiler, Andrea, Schumacher, Fabian, Kleuser, Burkhard

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Sphingosine 1-phosphate metabolism and insulin signaling von Wigger, Dominik, Schumacher, Fabian, Schneider-Schaulies, Sibylle, Kleuser, Burkhard

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Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide von Gulbins, Anne, Schumacher, Fabian, Becker, Katrin Anne, Wilker, Barbara, Soddemann, Matthias, Boldrin, Francesco, Müller, Christian P., Edwards, Michael J., Goodman, Michael, Caldwell, Charles C., Kleuser, Burkhard, Kornhuber, Johannes, Szabo, Ildiko, Gulbins, Erich

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The Role of Ten-Eleven Translocation Proteins in Inflammation von Gerecke, Christian, Egea Rodrigues, Caue, Homann, Thomas, Kleuser, Burkhard

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Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms von Folkesson, Maggie, PhD, Vorkapic, Emina, MSc, Gulbins, Erich, MD, Japtok, Lukasz, PhD, Kleuser, Burkhard, PhD, Welander, Martin, MD, Länne, Toste, MD, Wågsäter, Dick, PhD

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Enhanced Acid Sphingomyelinase Activity Drives Immune Evasion and Tumor Growth in Non-Small Cell Lung Carcinoma von Kachler, Katerina, Bailer, Maximilian, Heim, Lisanne, Schumacher, Fabian, Reichel, Martin, Holzinger, Corinna D, Trump, Sonja, Mittler, Susanne, Monti, Juliana, Trufa, Denis I, Rieker, Ralf J, Hartmann, Arndt, Sirbu, Horia, Kleuser, Burkhard, Kornhuber, Johannes, Finotto, Susetta

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Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation von Lotinun, Sutada, Kiviranta, Riku, Matsubara, Takuma, Alzate, Jorge A, Neff, Lynn, Lüth, Anja, Koskivirta, Ilpo, Kleuser, Burkhard, Vacher, Jean, Vuorio, Eero, Horne, William C, Baron, Roland

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Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease von Lang, Judith, Bohn, Patrick, Bhat, Hilal, Jastrow, Holger, Walkenfort, Bernd, Cansiz, Feyza, Fink, Julian, Bauer, Michael, Olszewski, Dominik, Ramos-Nascimento, Ana, Duhan, Vikas, Friedrich, Sarah-Kim, Becker, Katrin Anne, Krawczyk, Adalbert, Edwards, Michael J., Burchert, Andreas, Huber, Magdalena, Friebus-Kardash, Justa, Göthert, Joachim R., Hardt, Cornelia, Probst, Hans Christian, Schumacher, Fabian, Köhrer, Karl, Kleuser, Burkhard, Babiychuk, Eduard B., Sodeik, Beate, Seibel, Jürgen, Greber, Urs F., Lang, Philipp A., Gulbins, Erich, Lang, Karl S.

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Cell-intrinsic ceramides determine T cell function during melanoma progression von Hose, Matthias, Günther, Anne, Naser, Eyad, Schumacher, Fabian, Schönberger, Tina, Falkenstein, Julia, Papadamakis, Athanasios, Kleuser, Burkhard, Becker, Katrin Anne, Gulbins, Erich, Haimovitz-Friedman, Adriana, Buer, Jan, Westendorf, Astrid M, Hansen, Wiebke

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Vitamin C in combination with inhibition of mutant IDH1 synergistically activates TET enzymes and epigenetically modulates gene silencing in colon cancer cells von Gerecke, Christian, Schumacher, Fabian, Berndzen, Alide, Homann, Thomas, Kleuser, Burkhard

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The sphingosine 1-phosphate breakdown product, (2E)-hexadecenal, forms protein adducts and glutathione conjugates in vitro von Schumacher, Fabian, Neuber, Corinna, Finke, Hannah, Nieschalke, Kai, Baesler, Jessica, Gulbins, Erich, Kleuser, Burkhard

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Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro[S] von Naser, Eyad, Kadow, Stephanie, Schumacher, Fabian, Mohamed, Zainelabdeen H., Kappe, Christian, Hessler, Gabriele, Pollmeier, Barbara, Kleuser, Burkhard, Arenz, Christoph, Becker, Katrin Anne, Gulbins, Erich, Carpinteiro, Alexander

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Monitoring the Sphingolipid de novo Synthesis by Stable-Isotope Labeling and Liquid Chromatography-Mass Spectrometry von Wigger, Dominik, Gulbins, Erich, Kleuser, Burkhard, Schumacher, Fabian

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Liposomal FRET Assay Identifies Potent Drug‐Like Inhibitors of the Ceramide Transport Protein (CERT) von Samaha, Doaa, Hamdo, Housam H., Cong, Xiaojing, Schumacher, Fabian, Banhart, Sebastian, Aglar, Öznur, Möller, Heiko M., Heuer, Dagmar, Kleuser, Burkhard, Saied, Essa M., Arenz, Christoph

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Click-correlative light and electron microscopy (click-AT-CLEM) for imaging and tracking azido-functionalized sphingolipids in bacteria von Peters, Simon, Kaiser, Lena, Fink, Julian, Schumacher, Fabian, Perschin, Veronika, Schlegel, Jan, Sauer, Markus, Stigloher, Christian, Kleuser, Burkhard, Seibel, Jürgen, Schubert-Unkmeir, Alexandra

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Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach von Dubau, Marla, Tripetchr, Tarada, Mahmoud, Lava, Kral, Vivian, Kleuser, Burkhard

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Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells von Fohmann, Ingo, Weinmann, Alina, Schumacher, Fabian, Peters, Simon, Prell, Agata, Weigel, Cynthia, Spiegel, Sarah, Kleuser, Burkhard, Schubert-Unkmeir, Alexandra

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TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents von Wallmeyer, Leonie, Dietert, Kristina, Sochorová, Michaela, Gruber, Achim D., Kleuser, Burkhard, Vávrová, Kateřina, Hedtrich, Sarah

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