Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes von Kleinsorge, Mandy, Cyganek, Lukas

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Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V von Busley, Alexandra Viktoria, Kleinsorge, Mandy, Cyganek, Lukas

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Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome von Busley, Alexandra Viktoria, Gutiérrez-Gutiérrez, Óscar, Hammer, Elke, Koitka, Fabian, Mirzaiebadizi, Amin, Steinegger, Martin, Pape, Constantin, Böhmer, Linda, Schroeder, Henning, Kleinsorge, Mandy, Engler, Melanie, Cirstea, Ion Cristian, Gremer, Lothar, Willbold, Dieter, Altmüller, Janine, Marbach, Felix, Hasenfuss, Gerd, Zimmermann, Wolfram-Hubertus, Ahmadian, Mohammad Reza, Wollnik, Bernd, Cyganek, Lukas

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A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells von Zhong, Rujia, Schimanski, Theresa, Zhang, Feng, Lan, Huan, Hohn, Alyssa, Xu, Qiang, Huang, Mengying, Liao, Zhenxing, Qiao, Lin, Yang, Zhen, Li, Yingrui, Zhao, Zhihan, Li, Xin, Rose, Lena, Albers, Sebastian, Maywald, Lasse, Müller, Jonas, Dinkel, Hendrik, Saguner, Ardan, Janssen, Johannes W G, Swamy, Narasimha, Xi, Yannick, Lang, Siegfried, Kleinsorge, Mandy, Duru, Firat, Zhou, Xiaobo, Diecke, Sebastian, Cyganek, Lukas, Akin, Ibrahim, El-Battrawy, Ibrahim

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Human Mesenchymal Stem Cells Display Reduced Expression of CD105 after Culture in Serum-Free Medium von Mark, Peter, Kleinsorge, Mandy, Gaebel, Ralf, Lux, Cornelia A., Toelk, Anita, Pittermann, Erik, David, Robert, Steinhoff, Gustav, Ma, Nan

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Biphasic modulation of Wnt signaling supports efficient foregut endoderm formation from human pluripotent stem cells von Hoepfner, Jeannine, Kleinsorge, Mandy, Papp, Oliver, Ackermann, Mania, Alfken, Susanne, Rinas, Ursula, Solodenko, Wladimir, Kirschning, Andreas, Sgodda, Malte, Cantz, Tobias

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Studying Brugada Syndrome With an SCN1B Variants in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes von El-Battrawy, Ibrahim, Müller, Jonas, Zhao, Zhihan, Cyganek, Lukas, Zhong, Rujia, Zhang, Feng, Kleinsorge, Mandy, Lan, Huan, Li, Xin, Xu, Qiang, Huang, Mengying, Liao, Zhenxing, Moscu-Gregor, Alexander, Albers, Sebastian, Dinkel, Hendrik, Lang, Siegfried, Diecke, Sebastian, Zimmermann, Wolfram-Hubertus, Utikal, Jochen, Wieland, Thomas, Borggrefe, Martin, Zhou, Xiaobo, Akin, Ibrahim

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Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyoc... von El‐Battrawy, Ibrahim, Lan, Huan, Cyganek, Lukas, Maywald, Lasse, Zhong, Rujia, Zhang, Feng, Xu, Qiang, Lee, Jihyun, Duperrex, Eliane, Hierlemann, Andreas, Saguner, Ardan M., Duru, Firat, Kovacs, Boldizsar, Huang, Mengying, Liao, Zhenxing, Albers, Sebastian, Müller, Jonas, Dinkel, Hendrik, Rose, Lena, Hohn, Alyssa, Yang, Zhen, Qiao, Lin, Li, Yingrui, Lang, Siegfried, Kleinsorge, Mandy, Mügge, Andreas, Aweimer, Assem, Fan, Xuehui, Diecke, Sebastian, Akin, Ibrahim, Li, Guang, Zhou, Xiaobo

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In vitro models of human development and their potential application in developmental toxicity testing von Niethammer, Mirjam, Burgdorf, Tanja, Wistorf, Elisa, Schönfelder, Gilbert, Kleinsorge, Mandy

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Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome–Associated Cardiomyopathy von Hanses, Ulrich, Kleinsorge, Mandy, Roos, Lennart, Yigit, Gökhan, Li, Yun, Barbarics, Boris, El-Battrawy, Ibrahim, Lan, Huan, Tiburcy, Malte, Hindmarsh, Robin, Lenz, Christof, Salinas, Gabriela, Diecke, Sebastian, Müller, Christian, Adham, Ibrahim, Altmüller, Janine, Nürnberg, Peter, Paul, Thomas, Zimmermann, Wolfram-Hubertus, Hasenfuss, Gerd, Wollnik, Bernd, Cyganek, Lukas

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A cellular model of Brugada syndrome with SCN10A variants using human-induced pluripotent stem cell-derived cardiomyocytes von El-Battrawy, Ibrahim, Albers, Sebastian, Cyganek, Lukas, Zhao, Zhihan, Lan, Huan, Li, Xin, Xu, Qiang, Kleinsorge, Mandy, Huang, Mengying, Liao, Zhenxing, Zhong, Rujia, Rudic, Boris, Müller, Jonas, Dinkel, Hendrik, Lang, Siegfried, Diecke, Sebastian, Zimmermann, Wolfram-Hubertus, Utikal, Jochen, Wieland, Thomas, Borggrefe, Martin, Zhou, Xiaobo, Akin, Ibrahim

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A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells von Zhong, Rujia, Schimanski, Theresa, Zhang, Feng, Lan, Huan, Hohn, Alyssa, Xu, Qiang, Huang, Mengying, Liao, Zhenxing, Qiao, Lin, Yang, Zhen, Li, Yingrui, Zhao, Zhihan, Li, Xin, Rose, Lena, Albers, Sebastian, Maywald, Lasse, Müller, Jonas, Dinkel, Hendrik, Saguner, Ardan, Janssen, Johannes W G, Swamy, Narasimha, Xi, Yannick, Lang, Siegfried, Kleinsorge, Mandy, Duru, Firat, Zhou, Xiaobo, Diecke, Sebastian, Cyganek, Lukas, Akin, Ibrahim, El-Battrawy, Ibrahim

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In vitro modelling of familial amyloidotic polyneuropathy allows quantitative detection of transthyretin amyloid fibril-like structures in hepatic derivatives of patient-specific i... von Hoepfner, Jeannine, Kleinsorge, Mandy, Papp, Oliver, Alfken, Susanne, Heiringhoff, Robin, Pich, Andreas, Sauer, Vanessa, Zibert, Andree, Göhring, Gudrun, Schmidt, Hartmut, Sgodda, Malte, Cantz, Tobias

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Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene-edited human-induced pluripotent stem cell-derived cardiomyoc... von El-Battrawy, Ibrahim, Lan, Huan, Cyganek, Lukas, Maywald, Lasse, Zhong, Rujia, Zhang, Feng, Xu, Qiang, Lee, Jihyun, Duperrex, Eliane, Hierlemann, Andreas, Saguner, Ardan M., Duru, Firat, Kovacs, Boldizsar, Huang, Mengying, Liao, Zhenxing, Albers, Sebastian, Mueller, Jonas, Dinkel, Hendrik, Rose, Lena, Hohn, Alyssa, Yang, Zhen, Qiao, Lin, Li, Yingrui, Lang, Siegfried, Kleinsorge, Mandy, Muegge, Andreas, Aweimer, Assem, Fan, Xuehui, Diecke, Sebastian, Akin, Ibrahim, Li, Guang, Zhou, Xiaobo

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Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene-edited human-induced pluripotent stem cell-derived cardiomyoc... von El-Battrawy, Ibrahim, Lan, Huan, Cyganek, Lukas, Maywald, Lasse, Zhong, Rujia, Zhang, Feng, Xu, Qiang, Lee, Jihyun, Duperrex, Eliane, Hierlemann, Andreas, Saguner, Ardan M, Duru, Firat, Kovacs, Boldizsar, Huang, Mengying, Liao, Zhenxing, Albers, Sebastian, Müller, Jonas, Dinkel, Hendrik, Rose, Lena, Hohn, Alyssa, Yang, Zhen, Qiao, Lin, Li, Yingrui, Lang, Siegfried, Kleinsorge, Mandy, Mügge, Andreas, Aweimer, Assem, Fan, Xuehui, Diecke, Sebastian, Akin, Ibrahim

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