Regulatory T Cells As Potential Targets for HIV Cure Research von Kleinman, Adam J, Sivanandham, Ranjit, Pandrea, Ivona, Chougnet, Claire A, Apetrei, Cristian

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So Pathogenic or So What?-A Brief Overview of SIV Pathogenesis with an Emphasis on Cure Research von Kleinman, Adam J, Pandrea, Ivona, Apetrei, Cristian

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CD8+ T cells control SIV infection using both cytolytic effects and non-cytolytic suppression of virus production von Policicchio, Benjamin B., Cardozo-Ojeda, Erwing Fabian, Xu, Cuiling, Ma, Dongzhu, He, Tianyu, Raehtz, Kevin D., Sivanandham, Ranjit, Kleinman, Adam J., Perelson, Alan S., Apetrei, Cristian, Pandrea, Ivona, Ribeiro, Ruy M.

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Pharmacokinetics and Immunological Effects of Romidepsin in Rhesus Macaques von Kleinman, Adam J., Xu, Cuiling, Cottrell, Mackenzie L., Sivanandham, Ranjit, Brocca-Cofano, Egidio, Dunsmore, Tammy, Kashuba, Angela, Pandrea, Ivona, Apetrei, Cristian

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T cell activation is insufficient to drive SIV disease progression von Apetrei, Cristian, Gaufin, Thaidra, Brocca-Cofano, Egidio, Sivanandham, Ranjit, Sette, Paola, He, Tianyu, Sivanandham, Sindhuja, Martinez Sosa, Natalie, Martin, Kathryn J, Raehtz, Kevin D, Kleinman, Adam J, Valentine, Audrey, Krampe, Noah, Gautam, Rajeev, Lackner, Andrew A, Landay, Alan L, Ribeiro, Ruy M, Pandrea, Ivona

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Nonhuman Primate Testing of the Impact of Different Regulatory T Cell Depletion Strategies on Reactivation and Clearance of Latent Simian Immunodeficiency Virus von Sivanandham, Ranjit, Kleinman, Adam J., Sette, Paola, Brocca-Cofano, Egidio, Venkatraman, Sindhuja Murali Kilapandal, Policicchio, Benjamin B., He, Tianyu, Xu, Cuiling, Swarthout, Julia, Wang, Zhirui, Pandrea, Ivona, Apetrei, Cristian

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Changes to the Simian Immunodeficiency Virus (SIV) Reservoir and Enhanced SIV-Specific Responses in a Rhesus Macaque Model of Functional Cure after Serial Rounds of Romidepsin Admi... von Kleinman, Adam J, Sivanandham, Sindhuja, Sette, Paola, Sivanandham, Ranjit, Policicchio, Benjamin B, Xu, Cuiling, Penn, Ellen, Brocca-Cofano, Egidio, Le Hingrat, Quentin, Ma, Dongzhu, Pandrea, Ivona, Apetrei, Cristian

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Lack of Specific Regulatory T Cell Depletion and Cytoreduction Associated with Extensive Toxicity After Administration of Low and High Doses of Cyclophosphamide von Kleinman, Adam J, Sivanandham, Ranjit, Sette, Paola, Brocca-Cofano, Egidio, McAndrews, Colin, Keele, Brandon F, Pandrea, Ivona, Apetrei, Cristian

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Prolonged Antibody-Mediated CD4+ T-Cell Depletion Does Not Cause Disease Progression in Nonprogressively SIVagm-infected African Green Monkeys von Le Hingrat, Quentin, Sette, Paola, Xu, Cuiling, Rahmberg, Andrew, Tarnus, Lilas, Annapureddy, Haritha, Kleinman, Adam J., Brocca-Cofano, Egidio, Sivanandham, Ranjit, Sivanandham, Sindhuja, He, Tianyu, Capreri, Daniel, Tare, Minali, Ma, Dongzhu, D Estes, Jacob, Brenchley, Jason M., Apetrei, Cristian, Pandrea, Ivona

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Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways von Jansen, Philip R., Watanabe, Kyoko, Stringer, Sven, Skene, Nathan, Bryois, Julien, Hammerschlag, Anke R., de Leeuw, Christiaan A., Benjamins, Jeroen S., Muñoz-Manchado, Ana B., Nagel, Mats, Savage, Jeanne E., Tiemeier, Henning, White, Tonya, Tung, Joyce Y., Hinds, David A., Vacic, Vladimir, Wang, Xin, Sullivan, Patrick F., van der Sluis, Sophie, Polderman, Tinca J. C., Smit, August B., Hjerling-Leffler, Jens, Van Someren, Eus J. W., Posthuma, Danielle

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Estimated US Infection- and Vaccine-Induced SARS-CoV-2 Seroprevalence Based on Blood Donations, July 2020-May 2021 von Jones, Jefferson M, Stone, Mars, Sulaeman, Hasan, Fink, Rebecca V, Dave, Honey, Levy, Matthew E, Di Germanio, Clara, Green, Valerie, Notari, Edward, Saa, Paula, Biggerstaff, Brad J, Strauss, Donna, Kessler, Debra, Vassallo, Ralph, Reik, Rita, Rossmann, Susan, Destree, Mark, Nguyen, Kim-Anh, Sayers, Merlyn, Lough, Chris, Bougie, Daniel W, Ritter, Megan, Latoni, Gerardo, Weales, Billy, Sime, Stacy, Gorlin, Jed, Brown, Nicole E, Gould, Carolyn V, Berney, Kevin, Benoit, Tina J, Miller, Maureen J, Freeman, Dane, Kartik, Deeksha, Fry, Alicia M, Azziz-Baumgartner, Eduardo, Hall, Aron J, MacNeil, Adam, Gundlapalli, Adi V, Basavaraju, Sridhar V, Gerber, Susan I, Patton, Monica E, Custer, Brian, Williamson, Phillip, Simmons, Graham, Thornburg, Natalie J, Kleinman, Steven, Stramer, Susan L, Opsomer, Jean, Busch, Michael P

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Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways von Howard, David M., Adams, Mark J., Shirali, Masoud, Clarke, Toni-Kim, Marioni, Riccardo E., Davies, Gail, Coleman, Jonathan R. I., Alloza, Clara, Shen, Xueyi, Barbu, Miruna C., Wigmore, Eleanor M., Gibson, Jude, Hagenaars, Saskia P., Lewis, Cathryn M., Ward, Joey, Smith, Daniel J., Sullivan, Patrick F., Haley, Chris S., Breen, Gerome, Deary, Ian J., McIntosh, Andrew M.

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Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders von Walters, Raymond K., Polimanti, Renato, Adkins, Amy E., Aliev, Fazil, Bertelsen, Sarah, Biernacka, Joanna M., Bigdeli, Tim B., Chen, Li-Shiun, Degenhardt, Franziska, Docherty, Anna R., Foo, Jerome C., Frank, Josef, Gordon, Scott, Hartmann, Annette M., Hartz, Sarah M., Herms, Stefan, Hoffmann, Per, Jan Hottenga, Jouke, Konte, Bettina, Lahti, Jari, Lahti-Pulkkinen, Marius, Ligthart, Lannie, Loukola, Anu, Mbarek, Hamdi, McQueen, Matthew B., Milaneschi, Yuri, Palviainen, Teemu, Pearson, John F., Ripatti, Samuli, Salvatore, Jessica E., Schwandt, Melanie, Sherva, Richard, Webb, Bradley T., Wedow, Robbee, Wetherill, Leah, Wills, Amanda G., Chen, Danfeng, Choi, Doo-Sup, Copeland, William E., Dahmen, Norbert, Degenhardt, Louisa, Domingue, Benjamin W., Elson, Sarah L., Gäbel, Wolfgang, Ising, Marcus, Keyes, Margaret, Kiefer, Falk, Lucae, Susanne, Lynskey, Michael T., Maier, Wolfgang, Männistö, Satu, Nurnberger, John I., Palotie, Aarno, Preuss, Ulrich, Ridinger, Monika, Scherbaum, Norbert, Schuckit, Marc A., Soyka, Michael, Treutlein, Jens, Wodarz, Norbert, Adkins, Daniel E., Boden, Joseph M., Boomsma, Dorret I., Brown, Sandra A., Bucholz, Kathleen K., Cichon, Sven, Costello, E. Jane, Diazgranados, Nancy, Eriksson, Johan G., Foroud, Tatiana M., Gillespie, Nathan A., Hesselbrock, Victor, Hewitt, John K., Horwood, John, Johnson, Eric O., Kaprio, Jaakko A., Kendler, Kenneth S., Krauter, Kenneth, Lichtenstein, Paul, Lind, Penelope A., McGue, Matt, MacKillop, James, Madden, Pamela A. F., Martin, Nicholas G., Medland, Sarah E., Nöthen, Markus M., Palmer, Abraham A., Penninx, Brenda W. J. H., Porjesz, Bernice, Rice, John P., Rietschel, Marcella, Riley, Brien P., Rujescu, Dan, Shen, Pei-Hong, Silberg, Judy, Stallings, Michael C., Tarter, Ralph E., Vrieze, Scott, Wall, Tamara L., Whitfield, John B.

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Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways von Nagel, Mats, Jansen, Philip R., Stringer, Sven, Watanabe, Kyoko, de Leeuw, Christiaan A., Bryois, Julien, Savage, Jeanne E., Hammerschlag, Anke R., Skene, Nathan G., Muñoz-Manchado, Ana B., White, Tonya, Tiemeier, Henning, Linnarsson, Sten, Hjerling-Leffler, Jens, Polderman, Tinca J. C., Sullivan, Patrick F., van der Sluis, Sophie, Posthuma, Danielle

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Multi-trait analysis of genome-wide association summary statistics using MTAG von Turley, Patrick, Walters, Raymond K., Maghzian, Omeed, Okbay, Aysu, Lee, James J., Fontana, Mark Alan, Nguyen-Viet, Tuan Anh, Wedow, Robbee, Zacher, Meghan, Furlotte, Nicholas A., Magnusson, Patrik, Oskarsson, Sven, Johannesson, Magnus, Visscher, Peter M., Laibson, David, Cesarini, David, Neale, Benjamin M., Benjamin, Daniel J.

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Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use von Liu, Mengzhen, Jiang, Yu, Wedow, Robbee, Li, Yue, Brazel, David M., Chen, Fang, Datta, Gargi, Davila-Velderrain, Jose, Tian, Chao, Zhan, Xiaowei, Choquet, Hélène, Docherty, Anna R., Faul, Jessica D., Foerster, Johanna R., Fritsche, Lars G., Gabrielsen, Maiken Elvestad, Gordon, Scott D., Haessler, Jeffrey, Hottenga, Jouke-Jan, Huang, Hongyan, Jang, Seon-Kyeong, Jansen, Philip R., Ling, Yueh, Matoba, Nana, McMahon, George, Orrù, Valeria, Palviainen, Teemu, Pandit, Anita, Reginsson, Gunnar W., Skogholt, Anne Heidi, Smith, Jennifer A., Taylor, Amy E., Turman, Constance, Willemsen, Gonneke, Young, Hannah, Young, Kendra A., Zhao, Wei, Zhou, Wei, Bjornsdottir, Gyda, Boehnke, Michael, Boomsma, Dorret I., Chen, Chu, Cucca, Francesco, Davies, Gareth E., Eaton, Charles B., Ehringer, Marissa A., Esko, Tõnu, Fiorillo, Edoardo, Gillespie, Nathan A., Heath, Andrew C., Hokanson, John E., Hopfer, Christian J., Iacono, William G., Kamatani, Yoichiro, Kardia, Sharon L. R., Keller, Matthew C., Kellis, Manolis, Kooperberg, Charles, Kraft, Peter, Krauter, Kenneth S., Laakso, Markku, Lind, Penelope A., Loukola, Anu, Lutz, Sharon M., Madden, Pamela A. F., Martin, Nicholas G., McQueen, Matthew B., Medland, Sarah E., Mohlke, Karen L., Nielsen, Jonas B., Okada, Yukinori, Peters, Ulrike, Polderman, Tinca J. C., Rimm, Eric, Rose, Richard J., Runarsdottir, Valgerdur, Stallings, Michael C., Stefansson, Hreinn, Thai, Khanh K., Tindle, Hilary A., Tyrfingsson, Thorarinn, Wall, Tamara L., Weir, David R., Weisner, Constance, Whitfield, John B., Yin, Jie, Zuccolo, Luisa, Bierut, Laura J., Hveem, Kristian, Lee, James J., Munafò, Marcus R., Saccone, Nancy L., David, Sean P., Jorgenson, Eric, Kaprio, Jaakko, Stefansson, Kari, Thorgeirsson, Thorgeir E., Abecasis, Gonçalo, Liu, Dajiang J., Vrieze, Scott

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Characterization of Prevalence and Health Consequences of Uniparental Disomy in Four Million Individuals from the General Population von Nakka, Priyanka, Pattillo Smith, Samuel, O’Donnell-Luria, Anne H., McManus, Kimberly F., Agee, Michelle, Auton, Adam, Bell, Robert K., Bryc, Katarzyna, Elson, Sarah L., Fontanillas, Pierre, Furlotte, Nicholas A., Hicks, Barry, Hinds, David A., Jewett, Ethan M., Jiang, Yunxuan, Lin, Keng-Han, McCreight, Jennifer C., Huber, Karen E., Kleinman, Aaron, Litterman, Nadia K., McIntyre, Matthew H., Noblin, Elizabeth S., Northover, Carrie A.M., Pitts, Steven J., Poznik, G. David, Shelton, Janie F., Shringarpure, Suyash, Tian, Chao, Tung, Joyce Y., Vacic, Vladimir, Wang, Xin, Mountain, Joanna L., Ramachandran, Sohini, Sathirapongsasuti, J. Fah

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Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis von Gallagher, C. S., Mäkinen, N., Harris, H. R., Rahmioglu, N., Uimari, O., Cook, J. P., Shigesi, N., Ferreira, T., Velez-Edwards, D. R., Edwards, T. L., Mortlock, S., Ruhioglu, Z., Day, F., Becker, C. M., Karhunen, V., Martikainen, H., Järvelin, M.-R., Cantor, R. M., Ridker, P. M., Terry, K. L., Buring, J. E., Gordon, S. D., Medland, S. E., Montgomery, G. W., Nyholt, D. R., Hinds, D. A., Tung, J. Y., Perry, J. R. B., Lind, P. A., Painter, J. N., Martin, N. G., Morris, A. P., Chasman, D. I., Missmer, S. A., Zondervan, K. T., Morton, C. C.

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Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts von Sanchez-Roige, Sandra, Palmer, Abraham A, Fontanillas, Pierre, Elson, Sarah L, Adams, Mark J, Howard, David M, Edenberg, Howard J, Davies, Gail, Crist, Richard C, Deary, Ian J, McIntosh, Andrew M, Clarke, Toni-Kim

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Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals von Okbay, Aysu, Wu, Yeda, Wang, Nancy, Jayashankar, Hariharan, Bennett, Michael, Nehzati, Seyed Moeen, Sidorenko, Julia, Kweon, Hyeokmoon, Goldman, Grant, Gjorgjieva, Tamara, Jiang, Yunxuan, Hicks, Barry, Tian, Chao, Hinds, David A., Ahlskog, Rafael, Magnusson, Patrik K. E., Oskarsson, Sven, Hayward, Caroline, Campbell, Archie, Porteous, David J., Freese, Jeremy, Herd, Pamela, Watson, Chelsea, Jala, Jonathan, Conley, Dalton, Koellinger, Philipp D., Johannesson, Magnus, Laibson, David, Meyer, Michelle N., Lee, James J., Kong, Augustine, Yengo, Loic, Cesarini, David, Turley, Patrick, Visscher, Peter M., Beauchamp, Jonathan P., Benjamin, Daniel J., Young, Alexander I.

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