From multi-omics integration towards novel genomic interaction networks to identify key cancer cell line characteristics von Kuijpers, T. J. M., Kleinjans, J. C. S., Jennen, D. G. J.

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DynOVis: a web tool to study dynamic perturbations for capturing dose-over-time effects in biological networks von Kuijpers, T J M, Wolters, J E J, Kleinjans, J C S, Jennen, D G J

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A transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo von MAGKOUFOPOULOU, C, CLAESSEN, S. M. H, TSAMOU, M, JENNEN, D. G. J, KLEINJANS, J. C. S, DELFT, J. H. M. Van

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Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders von van den Berg, M.M.J., Krauskopf, J., Ramaekers, J.G., Kleinjans, J.C.S., Prickaerts, J., Briedé, J.J.

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Toxicogenomic profiles in relation to maternal immunotoxic exposure and immune functionality in newborns von Hochstenbach, Kevin, van Leeuwen, D M, Gmuender, H, Gottschalk, R W, Stølevik, S B, Nygaard, U C, Løvik, M, Granum, B, Namork, E, Meltzer, H M, Kleinjans, J C, van Delft, J H M, van Loveren, Henk

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Compound-specific effects of diverse neurodevelopmental toxicants on global gene expression in the neural embryonic stem cell test (ESTn) von Theunissen, P.T., Robinson, J.F., Pennings, J.L.A., van Herwijnen, M.H., Kleinjans, J.C.S., Piersma, A.H.

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Comparison of phenotypic and transcriptomic effects of false-positive genotoxins, true genotoxins and non-genotoxins using HepG2 cells von MAGKOUFOPOULOU, C, CLAESSEN, S. M. H, JENNEN, D. G. J, KLEINJANS, J. C. S, VAN DELFT, J. H. M

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Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling von van Delft, J. H. M., van Agen, E., van Breda, S. G. J., Herwijnen, M. H., Staal, Y. C. M., Kleinjans, J. C. S.

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Gene expression profiling in primary mouse hepatocytes discriminates true from false-positive genotoxic compounds von Mathijs, K., Brauers, K. J. J., Jennen, D. G. J., Lizarraga, D., Kleinjans, J. C. S., van Delft, J. H. M.

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A pro-inflammatory genotype predisposes to Barrett's esophagus von Moons, L.M.G., Kusters, J.G., van Delft, J.H.M., Kuipers, E.J., Gottschalk, R., Geldof, H., Bode, W.A., Stoof, J., van Vliet, A.H.M., Ketelslegers, H.B., Kleinjans, J.C.S., Siersema, P.D.

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Human 3D multicellular microtissues: An upgraded model for the in vitro mechanistic investigation of inflammation-associated drug toxicity von Jiang, J., Messner, S., Kelm, J.M., van Herwijnen, M., Jennen, D.G.J., Kleinjans, J.C., de Kok, T.M.

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Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: Toxicokinetics is essential for in vivo–in vitro comparisons von van Kesteren, P. C. E., Zwart, P. E., Schaap, M. M., Pronk, T. E., van Herwijnen, M. H. M., Kleinjans, J. C. S., Bokkers, B. G. H., Godschalk, R. W. L., Zeilmaker, M. J., van Steeg, H., Luijten, M.

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Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury von Jiang, J., Mathijs, K., Timmermans, L., Claessen, S.M., Hecka, A., Weusten, J., Peters, R., van Delft, J.H., Kleinjans, J.C.S., Jennen, D.G.J., de Kok, T.M.

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Baseline and genotoxic compound induced gene expression profiles in HepG2 and HepaRG compared to primary human hepatocytes von Jetten, M.J.A., Kleinjans, J.C.S., Claessen, S.M., Chesné, C., van Delft, J.H.M.

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Transcriptomic network analysis of micronuclei-related genes: a case study von van Leeuwen, D M, Pedersen, M, Knudsen, L E, Bonassi, S, Fenech, M, Kleinjans, J C S, Jennen, D G J

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Time series analysis of oxidative stress response patterns in HepG2: A toxicogenomics approach von Deferme, L, Briedé, J.J, Claessen, S.M.H, Jennen, D.G.J, Cavill, R, Kleinjans, J.C.S

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Cell line-specific oxidative stress in cellular toxicity: A toxicogenomics-based comparison between liver and colon cell models von Deferme, L., Briedé, J.J., Claessen, S.M.H., Cavill, R., Kleinjans, J.C.S.

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Inferring transcription factor activity from microarray data reveals novel targets for toxicological investigations von Souza, T.M., van den Beucken, T., Kleinjans, J.C.S., Jennen, D.G.J.

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Prediagnostic transcriptomic markers of Chronic lymphocytic leukemia reveal perturbations 10 years before diagnosis von Chadeau-Hyam, M., Vermeulen, R.C.H., Hebels, D.G.A.J., Castagné, R., Campanella, G., Portengen, L., Kelly, R.S., Bergdahl, I.A., Melin, B., Hallmans, G., Palli, D., Krogh, V., Tumino, R., Sacerdote, C., Panico, S., de Kok, T.M.C.M., Smith, M.T., Kleinjans, J.C.S., Vineis, P., Kyrtopoulos, S.A., Georgiadis, P., Botsivali, M., Papadopoulou, C., Chatziioannou, A., Valavanis, I., Gottschalk, R., van Leeuwen, D., Timmermans, L., Keun, H.C., Athersuch, T.J., Lenner, P., Bendinelli, B., Stephanou, E.G., Myridakis, A., Kogevinas, M., Saberi-Hosnijeh, F., Fazzo, L., de Santis, M., Comba, P., Kiviranta, H., Rantakokko, P., Airaksinen, R., Ruokojarvi, P., Gilthorpe, M.S., Fleming, S., Fleming, T., Tu, Y.-K., Jonsson, B., Lundh, T., Chien, K.-L., Chen, W.J., Lee, W.-C., Hsiao, C.K., Kuo, P.-H., Hung, H., Liao, S.-F.

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ToxDB: pathway-level interpretation of drug-treatment data von Hardt, C, Beber, M E, Rasche, A, Kamburov, A, Hebels, D G, Kleinjans, J C, Herwig, R

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