Development of insulin resistance in mice lacking PGC-1α in adipose tissues von Kleiner, Sandra, Mepani, Rina J, Laznik, Dina, Ye, Li, Jurczak, Michael J, Jornayvaz, Francois R, Estall, Jennifer L, Chatterjee Bhowmick, Diti, Shulman, Gerald I, Spiegelman, Bruce M

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TRPV4 Is a Regulator of Adipose Oxidative Metabolism, Inflammation, and Energy Homeostasis von Ye, Li, Kleiner, Sandra, Wu, Jun, Sah, Rajan, Gupta, Rana K, Banks, Alexander S, Cohen, Paul, Khandekar, Melin J, Boström, Pontus, Mepani, Rina J, Laznik, Dina, Kamenecka, Theodore M, Song, Xinyi, Liedtke, Wolfgang, Mootha, Vamsi K, Puigserver, Pere, Griffin, Patrick R, Clapham, David E, Spiegelman, Bruce M

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ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance[S] von Haller, Jorge F., Mintah, Ivory J., Shihanian, Lisa M., Stevis, Panayiotis, Buckler, David, Alexa-Braun, Corey A., Kleiner, Sandra, Banfi, Serena, Cohen, Jonathan C., Hobbs, Helen H., Yancopoulos, George D., Murphy, Andrew J., Gusarova, Viktoria, Gromada, Jesper

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ZnT8 Loss of Function Mutation Increases Resistance of Human Embryonic Stem Cell-Derived Beta Cells to Apoptosis in Low Zinc Condition von Sui, Lina, Du, Qian, Romer, Anthony, Su, Qi, Chabosseau, Pauline L, Xin, Yurong, Kim, Jinrang, Kleiner, Sandra, Rutter, Guy A, Egli, Dieter

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Whole‐Body Metabolism and the Musculoskeletal Impacts of Targeting Activin A and Myostatin in Severe Osteogenesis Imperfecta von Omosule, Catherine L., Joseph, Dominique, Weiler, Brooke, Gremminger, Victoria L., Silvey, Spencer, Lafaver, Brittany N., Jeong, Youngjae, Kleiner, Sandra, Phillips, Charlotte L.

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Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft size von Sui, Lina, Xin, Yurong, Du, Qian, Georgieva, Daniela, Diedenhofen, Giacomo, Haataja, Leena, Su, Qi, Zuccaro, Michael, Kim, Jinrang, Fu, Jiayu, Xing, Yuan, He, Yi, Baum, Danielle, Goland, Robin S., Wang, Yong, Oberholzer, Jose, Barbetti, Fabrizio, Arvan, Peter, Kleiner, Sandra, Egli, Dieter

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Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia von Kir, Serkan, White, James P., Kleiner, Sandra, Kazak, Lawrence, Cohen, Paul, Baracos, Vickie E., Spiegelman, Bruce M.

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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis von Fisher, Ffolliott M, Kleiner, Sandra, Douris, Nicholas, Fox, Elliott C, Mepani, Rina J, Verdeguer, Francisco, Wu, Jun, Kharitonenkov, Alexei, Flier, Jeffrey S, Maratos-Flier, Eleftheria, Spiegelman, Bruce M

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Non-redundant Role of Shc in Erk Activation by Cytoskeletal Reorganization von Faisal, Amir, Kleiner, Sandra, Nagamine, Yoshikuni

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A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy von Ruas, Jorge L., White, James P., Rao, Rajesh R., Kleiner, Sandra, Brannan, Kevin T., Harrison, Brooke C., Greene, Nicholas P., Wu, Jun, Estall, Jennifer L., Irving, Brian A., Lanza, Ian R., Rasbach, Kyle A., Okutsu, Mitsuharu, Nair, K. Sreekumaran, Yan, Zhen, Leinwand, Leslie A., Spiegelman, Bruce M.

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Zfp423 Expression Identifies Committed Preadipocytes and Localizes to Adipose Endothelial and Perivascular Cells von Gupta, Rana K., Mepani, Rina J., Kleiner, Sandra, Lo, James C., Khandekar, Melin J., Cohen, Paul, Frontini, Andrea, Bhowmick, Diti Chatterjee, Ye, Li, Cinti, Saverio, Spiegelman, Bruce M.

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IRF4 Is a Key Thermogenic Transcriptional Partner of PGC-1α von Kong, Xingxing, Banks, Alexander, Liu, Tiemin, Kazak, Lawrence, Rao, Rajesh R., Cohen, Paul, Wang, Xun, Yu, Songtao, Lo, James C., Tseng, Yu-Hua, Cypess, Aaron M., Xue, Ruidan, Kleiner, Sandra, Kang, Sona, Spiegelman, Bruce M., Rosen, Evan D.

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PPARδ Agonism Activates Fatty Acid Oxidation via PGC-1α but Does Not Increase Mitochondrial Gene Expression and Function von Kleiner, Sandra, Nguyen-Tran, Van, Baré, Olivia, Huang, Xueming, Spiegelman, Bruce, Wu, Zhidan

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Combinatorial Inhibition of Myostatin and Activin A Improves Femoral Bone Properties in the G610C Mouse Model of Osteogenesis Imperfecta von Omosule, Catherine L., Joseph, Dominique, Weiler, Brooke, Gremminger, Victoria L., Silvey, Spencer, Jeong, Youngjae, Rafique, Ashique, Krueger, Pamela, Kleiner, Sandra, Phillips, Charlotte L.

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Loss of ZnT8 function protects against diabetes by enhanced insulin secretion von Dwivedi, Om Prakash, Lehtovirta, Mikko, Hastoy, Benoit, Chandra, Vikash, Krentz, Nicole A. J., Kleiner, Sandra, Jain, Deepak, Richard, Ann-Marie, Abaitua, Fernando, Beer, Nicola L., Grotz, Antje, Prasad, Rashmi B., Hansson, Ola, Ahlqvist, Emma, Krus, Ulrika, Artner, Isabella, Suoranta, Anu, Gomez, Daniel, Baras, Aris, Champon, Benoite, Payne, Anthony J., Moralli, Daniela, Thomsen, Soren K., Kramer, Philipp, Spiliotis, Ioannis, Ramracheya, Reshma, Chabosseau, Pauline, Theodoulou, Andria, Cheung, Rebecca, van de Bunt, Martijn, Flannick, Jason, Trombetta, Maddalena, Bonora, Enzo, Wolheim, Claes B., Sarelin, Leena, Bonadonna, Riccardo C., Rorsman, Patrik, Davies, Benjamin, Brosnan, Julia, McCarthy, Mark I., Otonkoski, Timo, Lagerstedt, Jens O., Rutter, Guy A., Gromada, Jesper, Gloyn, Anna L., Tuomi, Tiinamaija, Groop, Leif

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Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity von Correia, Jorge C., Kelahmetoglu, Yildiz, Jannig, Paulo R., Schweingruber, Christoph, Shvaikovskaya, Dasha, Zhengye, Liu, Cervenka, Igor, Khan, Naveen, Stec, Michael, Oliveira, Mariana, Nijssen, Jik, Martínez-Redondo, Vicente, Ducommun, Serge, Azzolini, Michele, Lanner, Johanna T., Kleiner, Sandra, Hedlund, Eva, Ruas, Jorge L.

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Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity von Kleiner, Sandra, Gomez, Daniel, Megra, Bezawit, Na, Erqian, Bhavsar, Ramandeep, Cavino, Katie, Xin, Yurong, Rojas, Jose, Dominguez-Gutierrez, Giselle, Zambrowicz, Brian, Carrat, Gaelle, Chabosseau, Pauline, Hu, Ming, Murphy, Andrew J., Yancopoulos, George D., Rutter, Guy A., Gromada, Jesper

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Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation von Sczelecki, Sarah, Besse-Patin, Aurèle, Abboud, Alexandra, Kleiner, Sandra, Laznik-Bogoslavski, Dina, Wrann, Christiane D, Ruas, Jorge L, Haibe-Kains, Benjamin, Estall, Jennifer L

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A cellular and molecular spatial atlas of dystrophic muscle von Stec, Michael J, Su, Qi, Adler, Christina, Zhang, Lance, Golann, David R, Khan, Naveen P, Panagis, Lampros, Villalta, S Armando, Ni, Min, Wei, Yi, Walls, Johnathon R, Murphy, Andrew J, Yancopoulos, George D, Atwal, Gurinder S, Kleiner, Sandra, Halasz, Gabor, Sleeman, Mark W

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Impact of Genetic and Pharmacologic Inhibition of Myostatin in a Murine Model of Osteogenesis Imperfecta von Omosule, Catherine L, Gremminger, Victoria L, Aguillard, Ashley M, Jeong, Youngjae, Harrelson, Emily N, Miloscio, Lawrence, Mastaitis, Jason, Rafique, Ashique, Kleiner, Sandra, Pfeiffer, Ferris M, Zhang, Anqing, Schulz, Laura C, Phillips, Charlotte L

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