Is Parkinson's disease a lysosomal disorder? von Klein, Andrés D, Mazzulli, Joseph R

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Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria von Klein, Andrés D., Outeiro, Tiago Fleming

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Treating Niemann-Pick C lysosomal storage: approved and emerging approaches von Klein, Andrés D., Eden, Emily R., Zanlungo, Silvana

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Identification of Modifier Genes in a Mouse Model of Gaucher Disease von Klein, Andrés D., Ferreira, Natalia-Santos, Ben-Dor, Shifra, Duan, Jingjing, Hardy, John, Cox, Timothy M., Merrill, Alfred H., Futerman, Anthony H.

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The lysosomal β-glucocerebrosidase strikes mitochondria: implications for Parkinson's therapeutics von Rubilar, Juan Carlos, Outeiro, Tiago Fleming, Klein, Andrés D

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Modeling Parkinson’s Disease Heterogeneity to Accelerate Precision Medicine von Olivares, Gonzalo H., Olguín, Patricio, Klein, Andrés D.

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Gadolinium Chloride Rescues Niemann⁻Pick Type C Liver Damage von Klein, Andrés D, Oyarzún, Juan Esteban, Cortez, Cristian, Zanlungo, Silvana

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Genetic Background Matters: Population-Based Studies in Model Organisms for Translational Research von Olguín, Valeria, Durán, Anyelo, Las Heras, Macarena, Rubilar, Juan Carlos, Cubillos, Francisco A, Olguín, Patricio, Klein, Andrés D

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Complement Component C3 Participates in Early Stages of Niemann-Pick C Mouse Liver Damage von Klein, Andrés D, González de la Vega, Javier, Zanlungo, Silvana

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Rare diseases in Chile: challenges and recommendations in universal health coverage context von Encina, Gonzalo, Castillo-Laborde, Carla, Lecaros, Juan A, Dubois-Camacho, Karen, Calderón, Juan F, Aguilera, Ximena, Klein, Andrés D, Repetto, Gabriela M

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A Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids von Durán, Anyelo, Priestman, David A, Las Heras, Macarena, Rebolledo-Jaramillo, Boris, Olguín, Valeria, Calderón, Juan F, Zanlungo, Silvana, Gutiérrez, Jaime, Platt, Frances M, Klein, Andrés D

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Stroma-Derived Three-Dimensional Matrices Are Necessary and Sufficient to Promote Desmoplastic Differentiation of Normal Fibroblasts von Amatangelo, Michael D., Bassi, Daniel E., Klein-Szanto, Andrés J.P., Cukierman, Edna

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Understanding the phenotypic variability in Niemann-Pick disease type C (NPC): a need for precision medicine von Las Heras, Macarena, Szenfeld, Benjamín, Ballout, Rami A., Buratti, Emanuele, Zanlungo, Silvana, Dardis, Andrea, Klein, Andrés D.

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Neuronal and epithelial cell rescue resolves chronic systemic inflammation in the lipid storage disorder Niemann-Pick C von LOPEZ, Manuel E, KLEIN, Andrés D, HONG, Jennifer, DIMBIL, Ubah J, SCOTT, Matthew P

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Lack of Annexin A6 Exacerbates Liver Dysfunction and Reduces Lifespan of Niemann-Pick Type C Protein–Deficient Mice von Meneses-Salas, Elsa, Garcia-Forn, Marta, Castany-Pladevall, Carla, Lu, Albert, Fajardo, Alba, Jose, Jaimy, Wahba, Mohamed, Bosch, Marta, Pol, Albert, Tebar, Francesc, Klein, Andrés D., Zanlungo, Silvana, Pérez-Navarro, Esther, Grewal, Thomas, Enrich, Carlos, Rentero, Carles

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Disruption in connexin-based communication is associated with intracellular Ca²⁺ signal alterations in astrocytes from Niemann-Pick type C mice von Sáez, Pablo J, Orellana, Juan A, Vega-Riveros, Natalia, Figueroa, Vania A, Hernández, Diego E, Castro, Juan F, Klein, Andrés D, Jiang, Jean X, Zanlungo, Silvana, Sáez, Juan C

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Role of proteases in dysfunctional placental vascular remodelling in preeclampsia von Gutiérrez, Jaime A., Gómez, Isabel, Chiarello, Delia I., Salsoso, Rocío, Klein, Andrés D., Guzmán-Gutiérrez, Enrique, Toledo, Fernando, Sobrevia, Luis

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Brain Disorders Due to Lysosomal Dysfunction von Fraldi, Alessandro, Klein, Andrés D, Medina, Diego L, Settembre, Carmine

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c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder von Contreras, Pablo S., Tapia, Pablo J., González-Hódar, Lila, Peluso, Ivana, Soldati, Chiara, Napolitano, Gennaro, Matarese, Maria, Heras, Macarena Las, Valls, Cristian, Martinez, Alexis, Balboa, Elisa, Castro, Juan, Leal, Nancy, Platt, Frances M., Sobota, Andrzej, Winter, Dominic, Klein, Andrés D., Medina, Diego L., Ballabio, Andrea, Alvarez, Alejandra R., Zanlungo, Silvana

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Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells von Duhan, Vikas, Khairnar, Vishal, Kitanovski, Simo, Hamdan, Thamer A, Klein, Andrés D, Lang, Judith, Ali, Murtaza, Adomati, Tom, Bhat, Hilal, Friedrich, Sarah-Kim, Li, Fanghui, Krebs, Philippe, Futerman, Anthony H, Addo, Marylyn M, Hardt, Cornelia, Hoffmann, Daniel, Lang, Philipp A, Lang, Karl S

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