Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion von Tervonen, T A, Belitškin, D, Pant, S M, Englund, J I, Marques, E, Ala-Hongisto, H, Nevalaita, L, Sihto, H, Heikkilä, P, Leidenius, M, Hewitson, K, Ramachandra, M, Moilanen, A, Joensuu, H, Kovanen, P E, Poso, A, Klefström, J

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Par6G suppresses cell proliferation and is targeted by loss-of-function mutations in multiple cancers von Marques, E, Englund, J I, Tervonen, T A, Virkunen, E, Laakso, M, Myllynen, M, Mäkelä, A, Ahvenainen, M, Lepikhova, T, Monni, O, Hautaniemi, S, Klefström, J

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Liprin‐α1 contributes to oncogenic MAPK signaling by counteracting ERK activity von Pehkonen, Henna, Filippou, Artemis, Väänänen, Juho, Lindfors, Iida, Vänttinen, Mira, Ianevski, Philipp, Mäkelä, Anne, Munne, Pauliina, Klefström, Juha, Toppila‐Salmi, Sanna, Grénman, Reidar, Hagström, Jaana, Mäkitie, Antti A., Karhemo, Piia‐Riitta, Monni, Outi

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ANO1 Expression Orchestrates p27Kip1/MCL1-Mediated Signaling in Head and Neck Squamous Cell Carcinoma von Filippou, Artemis, Pehkonen, Henna, Karhemo, Piia-Riitta, Vaananen, Juho, Nieminen, Anni I., Klefstrom, Juha, Grenman, Reidar, Makitie, Antti A., Joensuu, Heikki, Monni, Outi

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173 Ras-mediated activation of mitogen-activated protein kinase pathway unleashes basement membrane damaging activity of serine protease hepsin von Tervonen, T, Pant, S, Belitskin, D, Englund, J, Närhi, K, Verschuren, E, Kovanen, P, Klefström, J

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380 Functional Properties of PPFIA1, Located at the 11q13 Amplification Region, in Epithelial Cancer Cells von Pehkonen, H, Lepikhova, T, Louhimo, R, Peitsaro, N, Imai, M, Martinez, R, Klefström, J, Hautaniemi, S, Monni, O

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Hepsin promotes breast tumor growth signaling via TGF beta-EGFR axis von Tervonen, T., Belitskin, D., Munne, P., Pant, S., Anttila, J., Belitskina, K., Pouwels, J., Klefström, J.

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Patient-Derived Explant Cultures (PDECs) as a Model System for Immuno-Oncology Studies von Turpin, R., Munne, P.M., Suleymanova, I., Mustjoki, S., Pouwels, J., Klefström, J.

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Laminin matrix adhesion regulates basal mammary epithelial cell identity von Englund, Johanna I, Bui, Hien, Dinç, Defne D, Paavolainen, Oona, McKenna, Tomás, Laitinen, Suvi, Munne, Pauliina, Klefström, Juha, Peuhu, Emilia, Katajisto, Pekka

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Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-κB activation von Klefstrom, Juha, Arighi, Elena, Littlewood, Trevor, Jäättelä, Marja, Saksela, Eero, Evan, Gerard I., Alitalo, Kari

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c‐Myc induces cellular susceptibility to the cytotoxic action of TNF‐alpha von Klefstrom, J., Västrik, I., Saksela, E., Valle, J., Eilers, M., Alitalo, K.

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The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo von Verschuren, Emmy W., Klefstrom, Juha, Evan, Gerard I., Jones, Nic

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Comparison of VEGF, VEGF-B, VEGF-C and ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia von ENHOLM, B, PAAVONEN, K, ERIKSSON, U, ALITALO, K, RISTIMÄKI, A, KUMAR, V, GUNJI, Y, KLEFSTROM, J, KIVINEN, L, LAIHO, M, OLOFSSON, B, JOUKOV, V

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c-Myc Augments the Apoptotic Activity of Cytosolic Death Receptor Signaling Proteins by Engaging the Mitochondrial Apoptotic Pathway von Klefstrom, Juha, Verschuren, Emmy W, Evan, Gerard

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BCL2 Overexpression Associated With Chromosomal Amplification in Diffuse Large B-Cell Lymphoma von Monni, Outi, Joensuu, Heikki, Franssila, Kaarle, Klefstrom, Juha, Alitalo, Kari, Knuutila, Sakari

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c-Myc and E1A induced cellular sensitivity to activated NK cells involves cytotoxic granules as death effectors von KLEFSTROM, J, KOVANEN, P. E, SOMERSALO, K, HUEBER, A.-O, LITTLEWOOD, T, EVAN, G. I, GREENBERG, A. H, SAKSELA, E, TIMONEN, T, ALITALO, K

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Induction of TNF-sensitive cellular phenotype by c-Myc involves p53 and impaired NF-kappaB activation von Klefstrom, J, Arighi, E, Littlewood, T, Jäättelä, M, Saksela, E, Evan, G I, Alitalo, K

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BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma von MONNI, O, JOENSUU, H, FRANSSILA, K, KLEFSTROM, J, ALITALO, K, KNUUTILA, S

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Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer von Lee, Joyce V., Housley, Filomena, Yau, Christina, Nakagawa, Rachel, Winkler, Juliane, Anttila, Johanna M., Munne, Pauliina M., Savelius, Mariel, Houlahan, Kathleen E., Van de Mark, Daniel, Hemmati, Golzar, Hernandez, Grace A., Zhang, Yibing, Samson, Susan, Baas, Carole, Kok, Marleen, Esserman, Laura J., van ‘t Veer, Laura J., Rugo, Hope S., Curtis, Christina, Klefström, Juha, Matloubian, Mehrdad, Goga, Andrei

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Similarities between TNF and exogenous oxidants on the cytotoxic response of c-Myc-expressing fibroblasts in vitro von Kinnula, Vuokko L, Aito, Henrikka, Klefstrom, Juha, Alitalo, Kari, Raivio, Kari O

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