Phase II trial of the anti-CD19 bispecific T cell-engager blinatumomab shows hematologic and molecular remissions in patients with relapsed or refractory B-precursor acute lymphobl... von Topp, Max S, Gökbuget, Nicola, Zugmaier, Gerhard, Klappers, Petra, Stelljes, Matthias, Neumann, Svenja, Viardot, Andreas, Marks, Reinhard, Diedrich, Helmut, Faul, Christoph, Reichle, Albrecht, Horst, Heinz-August, Brüggemann, Monika, Wessiepe, Dorothea, Holland, Chris, Alekar, Shilpa, Mergen, Noemi, Einsele, Hermann, Hoelzer, Dieter, Bargou, Ralf C

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Tumor Regression in Cancer Patients by Very Low Doses of a T Cell-Engaging Antibody von Bargou, Ralf, Leo, Eugen, Zugmaier, Gerhard, Klinger, Matthias, Goebeler, Mariele, Knop, Stefan, Noppeney, Richard, Viardot, Andreas, Hess, Georg, Schuler, Martin, Einsele, Hermann, Brandl, Christian, Wolf, Andreas, Kirchinger, Petra, Klappers, Petra, Schmidt, Margit, Riethmüller, Gert, Reinhardt, Carsten, Baeuerle, Patrick A, Kufer, Peter

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Anti-CD19 BiTE Blinatumomab Induces High Complete Remission Rate and Prolongs Overall Survival in Adult Patients with Relapsed/Refractory B-Precursor Acute Lymphoblastic Leukemia (... von Topp, Max S., Goekbuget, Nicola, Zugmaier, Gerhard, Viardot, Andreas, Stelljes, Matthias, Neumann, Svenja, Horst, Heinz A., Reichle, Albrecht, Marks, Reinhard, Faul, Christoph, Brueggemann, Monika, Ritgen, Matthias, Klappers, Petra, Mergen, Noemi, Goebeler, Marie-Elisabeth, Einsele, Hermann, Bargou, Ralf

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Effect of anti-CD19 BiTE blinatumomab on complete remission rate and overall survival in adult patients with relapsed/refractory B-precursor ALL von Topp, Max, Goekbuget, Nicola, Zugmaier, Gerhard, Viardot, Andreas, Stelljes, Matthias, Neumann, Svenja, Horst, Heinz-August, Reichle, Albrecht, Marks, Reinhard, Monika, Brueggemann, Ritgen, Matthias, Klappers, Petra, Mergen, Noemi, Goebeler, Marie-Elisabeth, Einsele, Hermann, Hoelzer, Dieter, Bargou, Ralph

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Anti-CD19 BiTE Blinatumomab Induces High Complete Remission Rate In Adult Patients with Relapsed B-Precursor ALL: Updated Results of An Ongoing Phase II Trial von Topp, Max S., Goekbuget, Nicola, Zugmaier, Gerhard, Viardot, Andreas, Stelljes, Matthias, Neumann, Svenja, Horst, Heinz A., Reichle, Albrecht, Marks, Reinhard E, Brueggemann, Monika, Ritgen, Matthias, Klappers, Petra, Mergen, Noemi, Goebeler, Marie-Elisabeth, Einsele, Hermann, Hoelzer, Dieter, Bargou, Ralf

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Treatment of Patients with Non-Hodgkin Lymphoma (NHL) with CD19/CD3 Bispecific Antibody Blinatumomab (MT103): Double-Step Dose Increase to Continuous Infusion of 60 μg/m2/d Is Tole... von Viardot, Andreas, Goebeler, Mariele, Scheele, Jurgen S., Zugmaier, Gerhard, Noppeney, Richard, Knop, Stefan, Topp, Max S, Nagorsen, Dirk, Klinger, Matthias, Schmidt, Margit, Klappers, Petra, Kufer, Peter, Einsele, Hermann, Bargou, Ralf

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Confirmation of Safety, Efficacy and Response Duration in Non-Hodgkin Lymphoma Patients Treated with 60 μg/m2/d of BiTE® Antibody Blinatumomab von Nagorsen, Dirk, Zugmaier, Gerhard, Viardot, Andreas, Goebeler, Mariele, Noppeney, Richard, Schmidt, Margit, Klappers, Petra, Baeuerle, Patrick A, Kufer, Peter, Bargou, Ralf C

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Transient Laboratory Findings Upon First Dosing with T-Cell Engaging BiTE® Antibody Blinatumomab in Non-Hodgkin Lymphoma Patients von Nagorsen, Dirk, Zugmaier, Gerhard, Kufer, Peter, Klinger, Matthias, Viardot, Andreas, Goebeler, Mariele, Schmidt, Margit, Klappers, Petra, Wolf, Andreas, Brandl, Christian, Baeuerle, Patrick A, Bargou, Ralf C

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Sustained Response Duration Seen after Treatment with Single Agent Blinatumomab (MT103/MEDI-538) in the Ongoing Phase I Study MT103- 104 in Patients with Relapsed NHL von Bargou, Ralf C, Kufer, Peter, Goebeler, Mariele, Knop, Stefan, Einsele, Hermann, Noppeney, Richard, Viardot, Andreas, Baeuerle, Patrick A, Reinhardt, Carsten, Schmidt, Margit, Klappers, Petra, Nagorsen, Dirk, Zugmaier, Gerhard

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A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma von Salaverria, Itziar, Martin-Guerrero, Idoia, Wagener, Rabea, Kreuz, Markus, Kohler, Christian W., Richter, Julia, Pienkowska-Grela, Barbara, Adam, Patrick, Burkhardt, Birgit, Claviez, Alexander, Damm-Welk, Christine, Drexler, Hans G., Hummel, Michael, Jaffe, Elaine S., Küppers, Ralf, Lefebvre, Christine, Lisfeld, Jasmin, Löffler, Markus, Macleod, Roderick A.F., Nagel, Inga, Oschlies, Ilske, Rosolowski, Maciej, Russell, Robert B., Rymkiewicz, Grzegorz, Schindler, Detlev, Schlesner, Matthias, Scholtysik, René, Schwaenen, Carsten, Spang, Rainer, Szczepanowski, Monika, Trümper, Lorenz, Vater, Inga, Wessendorf, Swen, Klapper, Wolfram, Siebert, Reiner

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Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma von Aukema, Sietse M, Kreuz, Markus, Kohler, Christian W, Rosolowski, Maciej, Hasenclever, Dirk, Hummel, Michael, Küppers, Ralf, Lenze, Dido, Ott, German, Pott, Christiane, Richter, Julia, Rosenwald, Andreas, Szczepanowski, Monika, Schwaenen, Carsten, Stein, Harald, Trautmann, Heiko, Wessendorf, Swen, Trümper, Lorenz, Loeffler, Markus, Spang, Rainer, Kluin, Philip M, Klapper, Wolfram, Siebert, Reiner

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New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling von Martín-Subero, José I., Kreuz, Markus, Bibikova, Marina, Bentink, Stefan, Ammerpohl, Ole, Wickham-Garcia, Eliza, Rosolowski, Maciej, Richter, Julia, Lopez-Serra, Lidia, Ballestar, Esteban, Berger, Hilmar, Agirre, Xabier, Bernd, Heinz-Wolfram, Calvanese, Vincenzo, Cogliatti, Sergio B., Drexler, Hans G., Fan, Jian-Bing, Fraga, Mario F., Hansmann, Martin L., Hummel, Michael, Klapper, Wolfram, Korn, Bernhard, Küppers, Ralf, MacLeod, Roderick A.F., Möller, Peter, Ott, German, Pott, Christiane, Prosper, Felipe, Rosenwald, Andreas, Schwaenen, Carsten, Schübeler, Dirk, Seifert, Marc, Stürzenhofecker, Benjamin, Weber, Michael, Wessendorf, Swen, Loeffler, Markus, Trümper, Lorenz, Stein, Harald, Spang, Rainer, Esteller, Manel, Barker, David, Hasenclever, Dirk, Siebert, Reiner

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The PCBP1 gene encoding poly(rc) binding protein i is recurrently mutated in Burkitt lymphoma von Wagener, Rabea, Aukema, Sietse M., Schlesner, Matthias, Haake, Andrea, Burkhardt, Birgit, Claviez, Alexander, Drexler, Hans G., Hummel, Michael, Kreuz, Markus, Loeffler, Markus, Rosolowski, Maciej, López, Cristina, Möller, Peter, Richter, Julia, Rohde, Marius, Betts, Matthew J., Russell, Robert B., Bernhart, Stephan H., Hoffmann, Steve, Rosenstiel, Philip, Schilhabel, Markus, Szczepanowski, Monika, Trümper, Lorenz, Klapper, Wolfram, Siebert, Reiner

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