Evidence for Elevated Cerebrospinal Fluid ERK1/2 Levels in Alzheimer Dementia von Spitzer, Philipp, Schieb, Heinke, Kamrowski-Kruck, Heike, Otto, Markus, Chiasserini, Davide, Parnetti, Lucilla, Herukka, Sanna-Kaisa, Schuchhardt, Johannes, Wiltfang, Jens G., Klafki, Hans-Wolfgang

Volltext

cNEUPRO : Novel Biomarkers for Neurodegenerative Diseases von Jimenez, Connie R., Herukka, Sanna-Kaisa, Esselmann, Hermann, Buée, Luc, Blennow, kaj, Klafki, Hans-Wolfgang, Spitzer, Philipp, Klivenyi, Peter, Lewczuk, Piotr, Maler, Juan Manuel, Markus, Katrin, Meyer, Helmut E., Morris, Chris, Müller, Thorsten, Otto, Markus, Parnetti, Lucilla, Soininen, Hilkka, Schraen, Susanna, Teunissen, Charlotte E., Vecsei, Laszlo, Zetterberg, Henrik, Wiltfang, Jens G.

Volltext

Detection and quantification of Aβ−3–40 (APP669‐711) in cerebrospinal fluid von Klafki, Hans‐Wolfgang, Wirths, Oliver, Mollenhauer, Brit, Liepold, Thomas, Rieper, Petra, Esselmann, Hermann, Vogelgsang, Jonathan, Wiltfang, Jens, Jahn, Olaf

Volltext

Blood plasma biomarkers for Alzheimer’s disease: Aβ1–42/1–40 vs. AβX–42/X–40 von Klafki, Hans-Wolfgang, Wirths, Oliver, Jahn, Olaf, Morgado, Barbara, Esselmann, Hermann, Wiltfang, Jens

Volltext

A Combination of Caffeine Supplementation and Enriched Environment in an Alzheimer's Disease Mouse Model von Stazi, Martina, Zampar, Silvia, Klafki, Hans-Wolfgang, Meyer, Thomas, Wirths, Oliver

Volltext

Therapeutic approaches to Alzheimer's disease von Klafki, Hans-Wolfgang, Staufenbiel, Matthias, Kornhuber, Johannes, Wiltfang, Jens

Volltext

Amino‐terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains von Wirths, Oliver, Lehnen, Christina, Fricke, Merle, Talucci, Ivan, Klafki, Hans‐Wolfgang, Morgado, Barbara, Lehmann, Sandra, Münch, Carolina, Liepold, Thomas, Wiltfang, Jens, Rostagno, Agueda, Ghiso, Jorge, Maric, Hans Michael, Jahn, Olaf, Weggen, Sascha

Volltext

Is plasma amyloid-β 1–42/1–40 a better biomarker for Alzheimer’s disease than AβX–42/X–40? von Klafki, Hans-Wolfgang, Morgado, Barbara, Wirths, Oliver, Jahn, Olaf, Bauer, Chris, Esselmann, Hermann, Schuchhardt, Johannes, Wiltfang, Jens

Volltext

Evaluation of cerebrospinal fluid glycoprotein NMB (GPNMB) as a potential biomarker for Alzheimer's disease von Aichholzer, Freyja, Klafki, Hans-Wolfgang, Ogorek, Isabella, Vogelgsang, Jonathan, Wiltfang, Jens, Scherbaum, Norbert, Weggen, Sascha, Wirths, Oliver

Volltext

Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides von Oberstein, Timo Jan, Spitzer, Philipp, Klafki, Hans-Wolfgang, Linning, Philipp, Neff, Florian, Knölker, Hans-Joachim, Lewczuk, Piotr, Wiltfang, Jens, Kornhuber, Johannes, Maler, Juan Manuel

Volltext

High-Fat Diet Induced Isoform Changes of the Parkinson’s Disease Protein DJ‑1 von Poschmann, Gereon, Seyfarth, Katrin, Besong Agbo, Daniela, Klafki, Hans-Wolfgang, Rozman, Jan, Wurst, Wolfgang, Wiltfang, Jens, Meyer, Helmut E, Klingenspor, Martin, Stühler, Kai

Volltext

Solid-Phase Synthesis and Characterization of N-Terminally Elongated Aβ−3-x-Peptides von Beyer, Isaak, Rezaei-Ghaleh, Nasrollah, Klafki, Hans-Wolfgang, Jahn, Olaf, Haußmann, Ute, Wiltfang, Jens, Zweckstetter, Markus, Knölker, Hans-Joachim

Volltext

Brain Region-Specific Differences in Amyloid-β Plaque Composition in 5XFAD Mice von Bader, Angelika Sabine, Gnädig, Marius-Uwe, Fricke, Merle, Büschgens, Luca, Berger, Lena Josefine, Klafki, Hans-Wolfgang, Meyer, Thomas, Jahn, Olaf, Weggen, Sascha, Wirths, Oliver

Volltext

Structural Design, Solid-Phase Synthesis and Activity of Membrane-Anchored β-Secretase Inhibitors on Aβ Generation from Wild-Type and Swedish-Mutant APP von Schieb, Heinke, Weidlich, Sebastian, Schlechtingen, Georg, Linning, Philipp, Jennings, Gary, Gruner, Margit, Wiltfang, Jens, Klafki, Hans-Wolfgang, Knölker, Hans-Joachim

Volltext

Assessment of immunoprecipitation with subsequent immunoassays for the blood-based diagnosis of Alzheimer's disease von Morgado, Barbara, Klafki, Hans-Wolfgang, Bauer, Chris, Waniek, Katharina, Esselmann, Hermann, Wirths, Oliver, Hansen, Niels, Lachmann, Ingolf, Osterloh, Dirk, Schuchhardt, Johannes, Wiltfang, Jens

Volltext

Urea-based two-dimensional electrophoresis of beta-amyloid peptides in human plasma: Evidence for novel Aβ species von Maler, Juan Manuel, Klafki, Hans-Wolfgang, Paul, Sabine, Spitzer, Philipp, Groemer, Teja Wolfgang, Henkel, Andreas Wolfram, Esselmann, Hermann, Lewczuk, Piotr, Kornhuber, Johannes, Wiltfang, Jens

Volltext

ERK1/2 protein and mRNA levels in human blood are linked to smoking behavior von Lenz, Bernd, Klafki, Hans-Wolfgang, Hillemacher, Thomas, Frieling, Helge, Clepce, Marion, Gossler, Andrea, Thuerauf, Norbert, Winterer, Georg, Kornhuber, Johannes, Bleich, Stefan

Volltext

The Role of Cathepsin B in the Degradation of A beta and in the Production of A beta Peptides Starting With Ala2 in Cultured Astrocytes von Oberstein, Timo Jan, Utz, Janine, Spitzer, Philipp, Klafki, Hans Wolfgang, Wiltfang, Jens, Lewczuk, Piotr, Kornhuber, Johannes, Maler, Juan Manuel

Volltext

Factors Responsible for Plasma β-Amyloid Accumulation in Chronic Kidney Disease von Gronewold, Janine, Klafki, Hans-Wolfgang, Baldelli, Enrico, Kaltwasser, Britta, Seidel, Ulla K., Todica, Olga, Volsek, Michaela, Haußmann, Ute, Wiltfang, Jens, Kribben, Andreas, Bruck, Heike, Hermann, Dirk M.

Volltext

Combined CSF tau, p-tau181 and amyloid-β 38/40/42 for diagnosing Alzheimer’s disease von Welge, Volker, Fiege, Oliver, Lewczuk, Piotr, Mollenhauer, Brit, Esselmann, Hermann, Klafki, Hans-Wolfgang, Wolf, Stefanie, Trenkwalder, Claudia, Otto, Markus, Kornhuber, Johannes, Wiltfang, Jens, Bibl, Mirko

Volltext