The Role of NLRP3 and IL-1β in the Pathogenesis of Inflammatory Bowel Disease von Mao, Liming, Kitani, Atsushi, Strober, Warren, Fuss, Ivan J

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A Mutation in the Nlrp3 Gene Causing Inflammasome Hyperactivation Potentiates Th17 Cell-Dominant Immune Responses von Meng, Guangxun, Zhang, Fuping, Fuss, Ivan, Kitani, Atsushi, Strober, Warren

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RICK/RIP2 is a NOD2-independent nodal point of gut inflammation von Watanabe, Tomohiro, Minaga, Kosuke, Kamata, Ken, Sakurai, Toshiharu, Komeda, Yoriaki, Nagai, Tomoyuki, Kitani, Atsushi, Tajima, Masaki, Fuss, Ivan J, Kudo, Masatoshi, Strober, Warren

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Cellular and molecular mechanisms underlying NOD2 risk-associated polymorphisms in Crohn's disease von Strober, Warren, Asano, Naoki, Fuss, Ivan, Kitani, Atsushi, Watanabe, Tomohiro

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IL-13 signaling through the IL-13α2 receptor is involved in induction of TGF-β1 production and fibrosis von Fichtner-Feigl, Stefan, Strober, Warren, Kawakami, Koji, Puri, Raj K, Kitani, Atsushi

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Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease von Mao, Liming, Kitani, Atsushi, Similuk, Morgan, Oler, Andrew J, Albenberg, Lindsey, Kelsen, Judith, Aktay, Atiye, Quezado, Martha, Yao, Michael, Montgomery-Recht, Kim, Fuss, Ivan J, Strober, Warren

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Positive and Negative Transcriptional Regulation of the Foxp3 Gene is Mediated by Access and Binding of the Smad3 Protein to Enhancer I von Xu, Lili, Kitani, Atsushi, Stuelten, Christina, McGrady, George, Fuss, Ivan, Strober, Warren

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Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function von Mao, Liming, Dhar, Atika, Meng, Guangxun, Fuss, Ivan, Montgomery-Recht, Kim, Yang, Zhiqiong, Xu, Qiuyun, Kitani, Atsushi, Strober, Warren

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NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway von Watanabe, Tomohiro, Asano, Naoki, Fichtner-Feigl, Stefan, Gorelick, Peter L, Tsuji, Yoshihisa, Matsumoto, Yuko, Chiba, Tsutomu, Fuss, Ivan J, Kitani, Atsushi, Strober, Warren

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IL-13 Signaling via IL-13Rα2 Induces Major Downstream Fibrogenic Factors Mediating Fibrosis in Chronic TNBS Colitis von Fichtner–Feigl, Stefan, Young, Cheryl A, Kitani, Atsushi, Geissler, Edward K, Schlitt, Hans–Jürgen, Strober, Warren

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Proinflammatory cytokines underlying the inflammation of Crohnʼs disease von Strober, Warren, Zhang, Fuping, Kitani, Atsushi, Fuss, Ivan, Fichtner-Feigl, Stefan

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Induction of IL-13 Triggers TGF-β1-Dependent Tissue Fibrosis in Chronic 2,4,6-Trinitrobenzene Sulfonic Acid Colitis von Fichtner-Feigl, Stefan, Fuss, Ivan J., Young, Cheryl A., Watanabe, Tomohiro, Geissler, Edward K., Schlitt, Hans-Jürgen, Kitani, Atsushi, Strober, Warren

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Nucleotide Binding Oligomerization Domain 2 Deficiency Leads to Dysregulated TLR2 Signaling and Induction of Antigen-Specific Colitis von Watanabe, Tomohiro, Kitani, Atsushi, Murray, Peter J., Wakatsuki, Yoshio, Fuss, Ivan J., Strober, Warren

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Restoration of Tumor Immunosurveillance via Targeting of Interleukin-13 Receptor-α2 von Fichtner-Feigl, Stefan, Terabe, Masaki, Kitani, Atsushi, Young, Cheryl A., Fuss, Ivan, Geissler, Edward K., Schlitt, Hans-Jürgen, Berzofsky, Jay A., Strober, Warren

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Tumor growth limited to subcutaneous site vs tumor growth in pulmonary site exhibit differential effects on systemic immunities von Masuda, Junko, Takayama, Eiji, Strober, Warren, Satoh, Ayano, Morimoto, Yuji, Honjo, Yasuko, Ichinohe, Tatsuo, Tokuno, Shin-Ichi, Ishizuka, Toshiaki, Nakata, Takahiro, Mizutani, Akifumi, Umemura, Naoki, Kitani, Atsushi, Fuss, Ivan J, Shigehiro, Tsukasa, Kawaki, Harumi, Mizuno-Kamiya, Masako, Kondoh, Nobuo, Seno, Masaharu

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NOD2 Transgenic Mice Exhibit Enhanced MDP-Mediated Down-Regulation of TLR2 Responses and Resistance to Colitis Induction von Yang, Zhiqiong, Fuss, Ivan J, Watanabe, Tomohiro, Asano, Naoki, Davey, Michael P, Rosenbaum, James T, Strober, Warren, Kitani, Atsushi

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Cutting Edge: Regulatory T Cells Induce CD4+CD25-Foxp3- T Cells or Are Self-Induced to Become Th17 Cells in the Absence of Exogenous TGF-beta von Xu, LiLi, Kitani, Atsushi, Fuss, Ivan, Strober, Warren

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Bruton tyrosine kinase deficiency augments NLRP3 inflammasome activation and causes IL-1 beta-mediated colitis von Mao, Liming, Kitani, Atsushi, Hiejima, Eitaro, Montgomery-Recht, Kim, Zhou, Wenchang, Fuss, Ivan, Wiestner, Adrian, Strober, Warren

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Activation of type I IFN signaling by NOD1 mediates mucosal host defense against Helicobacter pylori infection von Watanabe, Tomohiro, Asano, Naoki, Kitani, Atsushi, Fuss, Ivan J., Chiba, Tsutomu, Strober, Warren

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IL-13 signaling through the IL-13α 2 receptor is involved in induction of TGF-β 1 production and fibrosis von Strober, Warren, Fichtner-Feigl, Stefan, Kawakami, Koji, Puri, Raj K, Kitani, Atsushi

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