Site-Specific Proteasome Inhibitors von Kisselev, Alexei F

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Early recovery of proteasome activity in cells pulse-treated with proteasome inhibitors is independent of DDI2 von Ibtisam, Ibtisam, Kisselev, Alexei F

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NEIL3-mediated proteasomal degradation facilitates the repair of cisplatin-induced DNA damage in human cells von Aliyaskarova, Umit, Baiken, Yeldar, Renaud, Flore, Couve, Sophie, Kisselev, Alexei F., Saparbaev, Murat, Groisman, Regina

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Inhibition of the Proteasome β2 Site Sensitizes Triple-Negative Breast Cancer Cells to β5 Inhibitors and Suppresses Nrf1 Activation von Weyburne, Emily S., Wilkins, Owen M., Sha, Zhe, Williams, David A., Pletnev, Alexandre A., de Bruin, Gerjan, Overkleeft, Hermann S., Goldberg, Alfred L., Cole, Michael D., Kisselev, Alexei F.

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A clinically relevant pulse treatment generates a bortezomib-resistant myeloma cell line that lacks proteasome mutations and is sensitive to Bcl-2 inhibitor venetoclax von Downey-Kopyscinski, Sondra L., Srinivasa, Sriraja, Kisselev, Alexei F.

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Importance of the Different Proteolytic Sites of the Proteasome and the Efficacy of Inhibitors Varies with the Protein Substrate von Kisselev, Alexei F., Callard, Alice, Goldberg, Alfred L.

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Certain Pairs of Ubiquitin-conjugating Enzymes (E2s) and Ubiquitin-Protein Ligases (E3s) Synthesize Nondegradable Forked Ubiquitin Chains Containing All Possible Isopeptide Linkage... von Kim, Hyoung Tae, Kim, Kwang Pyo, Lledias, Fernando, Kisselev, Alexei F., Scaglione, K. Matthew, Skowyra, Dorota, Gygi, Steven P., Goldberg, Alfred L.

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A Novel Bullet Hits the Proteasome von Kisselev, Alexei F.

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Activity of immunoproteasome inhibitor ONX-0914 in acute lymphoblastic leukemia expressing MLL–AF4 fusion protein von Jenkins, Tyler W., Downey-Kopyscinski, Sondra L., Fields, Jennifer L., Rahme, Gilbert J., Colley, William C., Israel, Mark A., Maksimenko, Andrey V., Fiering, Steven N., Kisselev, Alexei F.

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Multiple BH3 Mimetics Antagonize Antiapoptotic MCL1 Protein by Inducing the Endoplasmic Reticulum Stress Response and Up-regulating BH3-only Protein NOXA von Albershardt, Tina C., Salerni, Bethany L., Soderquist, Ryan S., Bates, Darcy J.P., Pletnev, Alexandre A., Kisselev, Alexei F., Eastman, Alan

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The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage von Groisman, Regina, Polanowska, Jolanta, Kuraoka, Isao, Sawada, Jun-ichi, Saijo, Masafumi, Drapkin, Ronny, Kisselev, Alexei F., Tanaka, Kiyoji, Nakatani, Yoshihiro

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CSA-dependent degradation of CSB by the ubiquitin-proteasome pathway establishes a link between complementation factors of the Cockayne syndrome von Groisman, Regina, Kuraoka, Isao, Chevallier, Odile, Gaye, Nogaye, Magnaldo, Thierry, Tanaka, Kiyoji, Kisselev, Alexei F, Harel-Bellan, Annick, Nakatani, Yoshihiro

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Molecular basis of differential sensitivity of myeloma cells to clinically relevant bolus treatment with bortezomib von Shabaneh, Tamer B, Downey, Sondra L, Goddard, Ayrton L, Screen, Michael, Lucas, Marcella M, Eastman, Alan, Kisselev, Alexei F

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The novel β2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells von Kraus, Marianne, Bader, Juergen, Geurink, Paul P, Weyburne, Emily S, Mirabella, Anne C, Silzle, Tobias, Shabaneh, Tamer B, van der Linden, Wouter A, de Bruin, Gerjan, Haile, Sarah R, van Rooden, Eva, Appenzeller, Christina, Li, Nan, Kisselev, Alexei F, Overkleeft, Herman, Driessen, Christoph

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Subunit specific inhibitors of proteasomes and their potential for immunomodulation von Kisselev, Alexei F, Groettrup, Marcus

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DNA-Histone Cross-Links: Formation and Repair von Pachva, Manideep C., Kisselev, Alexei F., Matkarimov, Bakhyt T., Saparbaev, Murat, Groisman, Regina

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The Caspase-like Sites of Proteasomes, Their Substrate Specificity, New Inhibitors and Substrates, and Allosteric Interactions with the Trypsin-like Sites von Kisselev, Alexei F., Garcia-Calvo, Margarita, Overkleeft, Herman S., Peterson, Erin, Pennington, Michael W., Ploegh, Hidde L., Thornberry, Nancy A., Goldberg, Alfred L.

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Proteasome Active Sites Allosterically Regulate Each Other, Suggesting a Cyclical Bite-Chew Mechanism for Protein Breakdown von Kisselev, Alexei F, Akopian, Tatos N, Castillo, Vanesa, Goldberg, Alfred L

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Monitoring Activity and Inhibition of 26S Proteasomes with Fluorogenic Peptide Substrates von Kisselev, Alexei F., Goldberg, Alfred L.

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A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities von de Bruin, Gerjan, Xin, Bo Tao, Kraus, Marianne, van der Stelt, Mario, van der Marel, Gijsbert A., Kisselev, Alexei F., Driessen, Christoph, Florea, Bogdan I., Overkleeft, Herman S.

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