Metabolic reprograming of anti-tumor immunity von Sukumar, Madhusudhanan, Kishton, Rigel J, Restifo, Nicholas P

Volltext

Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human Lymphomas von Dersh, Devin, Phelan, James D., Gumina, Megan E., Wang, Boya, Arbuckle, Jesse H., Holly, Jaroslav, Kishton, Rigel J., Markowitz, Tovah E., Seedhom, Mina O., Fridlyand, Nathan, Wright, George W., Huang, Da Wei, Ceribelli, Michele, Thomas, Craig J., Lack, Justin B., Restifo, Nicholas P., Kristie, Thomas M., Staudt, Louis M., Yewdell, Jonathan W.

Volltext

AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival von Kishton, Rigel J., Barnes, Carson E., Nichols, Amanda G., Cohen, Sivan, Gerriets, Valerie A., Siska, Peter J., Macintyre, Andrew N., Goraksha-Hicks, Pankuri, de Cubas, Aguirre A., Liu, Tingyu, Warmoes, Marc O., Abel, E. Dale, Yeoh, Allen Eng Juh, Gershon, Timothy R., Rathmell, W. Kimryn, Richards, Kristy L., Locasale, Jason W., Rathmell, Jeffrey C.

Volltext

Arginine Arms T Cells to Thrive and Survive von Kishton, Rigel J., Sukumar, Madhusudhanan, Restifo, Nicholas P.

Volltext

Metabolic Regulation of T Cell Longevity and Function in Tumor Immunotherapy von Kishton, Rigel J., Sukumar, Madhusudhanan, Restifo, Nicholas P.

Volltext

A guide to immunometabolism for immunologists von O'Neill, Luke A. J., Kishton, Rigel J., Rathmell, Jeff

Volltext

CDK4/6 Therapeutic Intervention and Viable Alternative to Taxanes in CRPC von Stice, James P, Wardell, Suzanne E, Norris, John D, Yllanes, Alexander P, Alley, Holly M, Haney, Victoria O, White, Hannah S, Safi, Rachid, Winter, Peter S, Cocce, Kimberly J, Kishton, Rigel J, Lawrence, Scott A, Strum, Jay C, McDonnell, Donald P

Volltext

Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression von Gerriets, Valerie A, Kishton, Rigel J, Johnson, Marc O, Cohen, Sivan, Siska, Peter J, Nichols, Amanda G, Warmoes, Marc O, de Cubas, Aguirre A, MacIver, Nancie J, Locasale, Jason W, Turka, Laurence A, Wells, Andrew D, Rathmell, Jeffrey C

Volltext

mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation von Zeng, Hu, Cohen, Sivan, Guy, Cliff, Shrestha, Sharad, Neale, Geoffrey, Brown, Scott A., Cloer, Caryn, Kishton, Rigel J., Gao, Xia, Youngblood, Ben, Do, Mytrang, Li, Ming O., Locasale, Jason W., Rathmell, Jeffrey C., Chi, Hongbo

Volltext

Next generation immunotherapy: enhancing stemness of polyclonal T cells to improve anti-tumor activity von Kishton, Rigel J, Vodnala, Suman K, Vizcardo, Raul, Restifo, Nicholas P

Volltext

Strength in Numbers: Identifying Neoantigen Targets for Cancer Immunotherapy von Kishton, Rigel J., Lynn, Rachel C., Restifo, Nicholas P.

Volltext

Fine-tuning T cell function through engineered orthogonal chimeric cytokine receptors von Kishton, Rigel J., Restifo, Nicholas P.

Volltext

T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy von Yamamoto, Tori N, Lee, Ping-Hsien, Vodnala, Suman K, Gurusamy, Devikala, Kishton, Rigel J, Yu, Zhiya, Eidizadeh, Arash, Eil, Robert, Fioravanti, Jessica, Gattinoni, Luca, Kochenderfer, James N, Fry, Terry J, Aksoy, Bulent Arman, Hammerbacher, Jeffrey E, Cruz, Anthony C, Siegel, Richard M, Restifo, Nicholas P, Klebanoff, Christopher A

Volltext

Leptin directly promotes T‐cell glycolytic metabolism to drive effector T‐cell differentiation in a mouse model of autoimmunity von Gerriets, Valerie A., Danzaki, Keiko, Kishton, Rigel J., Eisner, William, Nichols, Amanda G., Saucillo, Donte C., Shinohara, Mari L., MacIver, Nancie J.

Volltext

A T cell resilience model associated with response to immunotherapy in multiple tumor types von Zhang, Yu, Vu, Trang, Palmer, Douglas C., Kishton, Rigel J., Gong, Lanqi, Huang, Jiao, Nguyen, Thanh, Chen, Zuojia, Smith, Cari, Livák, Ferenc, Paul, Rohit, Day, Chi-Ping, Wu, Chuan, Merlino, Glenn, Aldape, Kenneth, Guan, Xin-yuan, Jiang, Peng

Volltext

Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells von Lee, Ping-Hsien, Yamamoto, Tori N, Gurusamy, Devikala, Sukumar, Madhusudhanan, Yu, Zhiya, Hu-Li, Jane, Kawabe, Takeshi, Gangaplara, Arunakumar, Kishton, Rigel J, Henning, Amanda N, Vodnala, Suman K, Germain, Ronald N, Paul, William E, Restifo, Nicholas P

Volltext

Publisher Correction: A T cell resilience model associated with response to immunotherapy in multiple tumor types von Zhang, Yu, Vu, Trang, Palmer, Douglas C., Kishton, Rigel J., Gong, Lanqi, Huang, Jiao, Nguyen, Thanh, Chen, Zuojia, Smith, Cari, Livák, Ferenc, Paul, Rohit, Day, Chi-Ping, Wu, Chuan, Merlino, Glenn, Aldape, Kenneth, Guan, Xin-yuan, Jiang, Peng

Volltext

Mechanistic Investigation of Site-specific DNA Methylating Agents Targeting Breast Cancer Cells von Lowder, Leah L, Powell, Matthew, Miller, Sean E, Kishton, Rigel J, Kelly, Charles B, Cribb, Connor B, Mastro-Kishton, Kelly, Chelvanambi, Manoj, Do, Phat T, Govindapur, Rajeshwar Reddy, Wardell, Suzanne E, McDonnell, Donald P, Bartolotti, Libero J, Akkaraju, Giridhar R, Frampton, Arthur R, Varadarajan, Sridhar

Volltext

Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade von Palmer, Douglas C, Webber, Beau R, Patel, Yogin, Johnson, Matthew J, Kariya, Christine M, Lahr, Walker S, Parkhurst, Maria R, Gartner, Jared J, Prickett, Todd D, Lowery, Frank J, Kishton, Rigel J, Gurusamy, Devikala, Franco, Zulmarie, Vodnala, Suman K, Diers, Miechaleen D, Wolf, Natalie K, Slipek, Nicholas J, McKenna, David H, Sumstad, Darin, Viney, Lydia, Henley, Tom, Bürckstümmer, Tilmann, Baker, Oliver, Hu, Ying, Yan, Chunhua, Meerzaman, Daoud, Padhan, Kartik, Lo, Winnie, Malekzadeh, Parisa, Jia, Li, Deniger, Drew C, Patel, Shashank J, Robbins, Paul F, McIvor, R Scott, Choudhry, Modassir, Rosenberg, Steven A, Moriarity, Branden S, Restifo, Nicholas P

Volltext

Reprogramming of Tumor-reactive Tumor-infiltrating Lymphocytes to Human-induced Pluripotent Stem Cells von Islam, S M Rafiqul, Maeda, Takuya, Tamaoki, Naritaka, Good, Meghan L, Kishton, Rigel J, Paria, Biman C, Yu, Zhiya, Bosch-Marce, Marta, Bedanova, Nicole M, Liu, Chengyu, Kruhlak, Michael J, Restifo, Nicholas P, Vizcardo, Raul

Volltext