Development of ImmTOR Tolerogenic Nanoparticles for the Mitigation of Anti-drug Antibodies von Kishimoto, Takashi Kei

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Nanoparticles for the Induction of Antigen-Specific Immunological Tolerance von Kishimoto, Takashi Kei, Maldonado, Roberto A

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Antigen-selective modulation of AAV immunogenicity with tolerogenic rapamycin nanoparticles enables successful vector re-administration von Meliani, Amine, Boisgerault, Florence, Hardet, Romain, Marmier, Solenne, Collaud, Fanny, Ronzitti, Giuseppe, Leborgne, Christian, Costa Verdera, Helena, Simon Sola, Marcelo, Charles, Severine, Vignaud, Alban, van Wittenberghe, Laetitia, Manni, Giorgia, Christophe, Olivier, Fallarino, Francesca, Roy, Christopher, Michaud, Alicia, Ilyinskii, Petr, Kishimoto, Takashi Kei, Mingozzi, Federico

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Tolerogenic nanoparticles mitigate the formation of anti-drug antibodies against pegylated uricase in patients with hyperuricemia von Sands, Earl, Kivitz, Alan, DeHaan, Wesley, Leung, Sheldon S., Johnston, Lloyd, Kishimoto, Takashi Kei

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Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance von Maldonado, Roberto A., LaMothe, Robert A., Ferrari, Joseph D., Zhang, Ai-Hong, Rossi, Robert J., Kolte, Pallavi N., Griset, Aaron P., O’Neil, Conlin, Altreuter, David H., Browning, Erica, Johnston, Lloyd, Farokhzad, Omid C., Langer, Robert, Scott, David W., von Andrian, Ulrich H., Kishimoto, Takashi Kei

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M402, a novel heparan sulfate mimetic, targets multiple pathways implicated in tumor progression and metastasis von Zhou, He, Roy, Sucharita, Cochran, Edward, Zouaoui, Radouane, Chu, Chia Lin, Duffner, Jay, Zhao, Ganlin, Smith, Sean, Galcheva-Gargova, Zoya, Karlgren, Juliane, Dussault, Nancy, Kwan, Rain Y Q, Moy, Erick, Barnes, Marishka, Long, Alison, Honan, Chris, Qi, Yi Wei, Shriver, Zachary, Ganguly, Tanmoy, Schultes, Birgit, Venkataraman, Ganesh, Kishimoto, Takashi Kei

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Non-invasive detection of a small number of bioluminescent cancer cells in vivo von Kim, Jae-Beom, Urban, Konnie, Cochran, Edward, Lee, Steve, Ang, Angel, Rice, Bradley, Bata, Adam, Campbell, Kenneth, Coffee, Richard, Gorodinsky, Alex, Lu, Zhan, Zhou, He, Kishimoto, Takashi Kei, Lassota, Peter

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Enhancement of the Tolerogenic Phenotype in the Liver by ImmTOR Nanoparticles von Ilyinskii, Petr O, Roy, Christopher J, LePrevost, Julie, Rizzo, Gina L, Kishimoto, Takashi Kei

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Outbreak of Adverse Reactions Associated with Contaminated Heparin von Blossom, David B, Kallen, Alexander J, Patel, Priti R, Elward, Alexis, Robinson, Luke, Gao, Ganpan, Langer, Robert, Perkins, Kiran M, Jaeger, Jennifer L, Kurkjian, Katie M, Jones, Marilyn, Schillie, Sarah F, Shehab, Nadine, Ketterer, Daniel, Venkataraman, Ganesh, Kishimoto, Takashi Kei, Shriver, Zachary, McMahon, Ann W, Austen, K. Frank, Kozlowski, Steven, Srinivasan, Arjun, Turabelidze, George, Gould, Carolyn V, Arduino, Matthew J, Sasisekharan, Ram

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Synthetic vaccine particles for durable cytolytic T lymphocyte responses and anti-tumor immunotherapy von Ilyinskii, Petr O, Kovalev, Grigoriy I, O'Neil, Conlin P, Roy, Christopher J, Michaud, Alicia M, Drefs, Natalia M, Pechenkin, Mikhail A, Fu, Fen-Ni, Johnston, Lloyd P M, Ovchinnikov, Dmitry A, Kishimoto, Takashi Kei

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ImmTOR nanoparticles enhance AAV transgene expression after initial and repeat dosing in a mouse model of methylmalonic acidemia von Ilyinskii, Petr O., Michaud, Alicia M., Rizzo, Gina L., Roy, Christopher J., Leung, Sheldon S., Elkins, Stephanie L., Capela, Teresa, Chowdhury, Aparajita, Li, Lina, Chandler, Randy J., Manoli, Irini, Andres-Mateos, Eva, Johnston, Lloyd P.M., Vandenberghe, Luk H., Venditti, Charles P., Kishimoto, Takashi Kei

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Long-term correction of ornithine transcarbamylase deficiency in Spf-Ash mice with a translationally optimized AAV vector von De Sabbata, Giulia, Boisgerault, Florence, Guarnaccia, Corrado, Iaconcig, Alessandra, Bortolussi, Giulia, Collaud, Fanny, Ronzitti, Giuseppe, Sola, Marcelo Simon, Vidal, Patrice, Rouillon, Jeremy, Charles, Severine, Nicastro, Emanuele, D’Antiga, Lorenzo, Ilyinskii, Petr, Mingozzi, Federico, Kishimoto, Takashi Kei, Muro, Andrés F.

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Diverse Cell Surface Protein Ectodomains Are Shed by a System Sensitive to Metalloprotease Inhibitors (∗) von Arribas, Joaquin, Coodly, Lavanya, Vollmer, Petra, Kishimoto, Takashi Kei, Rose-John, Stefan, Massagué, Joan

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M118 – A rationally engineered low-molecular-weight heparin designed specifically for the treatment of acute coronary syndromes von Kishimoto, Takashi Kei, Qi, Yi Wei, Long, Alison, Capila, Ishan, Sasisekharan, Ram, Guerrero, Luis, Fier, Ian, Roach, James, Venkataraman, Ganesh

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ImmTORTM to amplify the efficacy and reduce immunogenicity of biologics von Brunn, Carsten, Kishimoto, Takashi Kei

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Tolerogenic nanoparticles restore the antitumor activity of recombinant immunotoxins by mitigating immunogenicity von Mazor, Ronit, King, Emily M., Onda, Masanori, Cuburu, Nicolas, Addissie, Selamawit, Crown, Devorah, Liu, Xiu-Fen, Kishimoto, Takashi Kei, Pastan, Ira

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Neutrophil Mac-1 and MEL-14 Adhesion Proteins Inversely Regulated by Chemotactic Factors von Kishimoto, Takashi Kei, Jutila, Mark A., Berg, Ellen Lakey, Butcher, Eugene C.

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Abstract 72: Induction of immune tolerance to recombinant immunotoxin LMB-100 using synthetic vaccine particles encapsulating rapamycin von Mazor, Ronit, King, Emily, Kishimoto, Takashi Kei, Pastan, Ira

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Immune tolerance to recombinant immunotoxin LMB-100 using synthetic vaccine particles encapsulating rapamycin von Mazor, Ronit, King, Emily, Kishimoto, Takashi Kei, Pastan, Ira

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Identification of N-terminal Residues on P-selectin Glycoprotein Ligand-1 Required for Binding to P-selectin von Liu, W, Ramachandran, V, Kang, J, Kishimoto, T K, Cummings, R D, McEver, R P

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