Human induced pluripotent stem cell derived hepatocytes provide insights on parenteral nutrition associated cholestasis in the immature liver von Nghiem-Rao, T. Hang, Pfeifer, Courtney, Asuncion, Michelle, Nord, Joshua, Schill, Daniel, Pulakanti, Kirthi, Patel, Shailendra B., Cirillo, Lisa A., Rao, Sridhar

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Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes von Blinka, Steven, Reimer, Michael H., Pulakanti, Kirthi, Rao, Sridhar

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DOT1L inhibitors block abnormal self-renewal induced by cohesin loss von Heimbruch, Katelyn E., Fisher, Joseph B., Stelloh, Cary T., Phillips, Emily, Reimer, Michael H., Wargolet, Adam J., Meyer, Alison E., Pulakanti, Kirthi, Viny, Aaron D., Loppnow, Jessica J., Levine, Ross L., Pulikkan, John Anto, Zhu, Nan, Rao, Sridhar

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Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance von Palma, Flavio R., Coelho, Diego R., Pulakanti, Kirthi, Sakiyama, Marcelo J., Huang, Yunping, Ogata, Fernando T., Danes, Jeanne M., Meyer, Alison, Furdui, Cristina M., Spitz, Douglas R., Gomes, Ana P., Gantner, Benjamin N., Rao, Sridhar, Backman, Vadim, Bonini, Marcelo G.

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Generation and validation of a conditional knockout mouse model for desmosterolosis von Kanuri, Babunageswararao, Fong, Vincent, Ponny, Sithara Raju, Weerasekera, Ranjuna, Pulakanti, Kirthi, Patel, Kriya S., Tyshynsky, Roman, Patel, Shailendra B.

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T Cells Deficient in Diacylglycerol Kinase ζ Are Resistant to PD-1 Inhibition and Help Create Persistent Host Immunity to Leukemia von Jing, Weiqing, Gershan, Jill A, Holzhauer, Sandra, Weber, James, Palen, Katie, McOlash, Laura, Pulakanti, Kirthi, Wesley, Erin, Rao, Sridhar, Johnson, Bryon D, Riese, Matthew J

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Mature IgDlow/- B cells maintain tolerance by promoting regulatory T cell homeostasis von Ray, Avijit, Khalil, Mohamed I., Pulakanti, Kirthi L., Burns, Robert T., Gurski, Cody J., Basu, Sreemanti, Wang, Demin, Rao, Sridhar, Dittel, Bonnie N.

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Dynamic Switching of Active Promoter and Enhancer Domains Regulates Tet1 and Tet2 Expression during Cell State Transitions between Pluripotency and Differentiation von Sohni, Abhishek, Bartoccetti, Michela, Khoueiry, Rita, Spans, Lien, Vande Velde, Joris, De Troyer, Linde, Pulakanti, Kirthi, Claessens, Frank, Rao, Sridhar, Koh, Kian Peng

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Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance von Palma, Flavio R., Coelho, Diego R., Pulakanti, Kirthi, Sakiyama, Marcelo J., Huang, Yunping, Ogata, Fernando T., Danes, Jeanne M., Meyer, Alison, Furdui, Cristina M., Spitz, Douglas R., Gomes, Ana P., Gantner, Benjamin N., Rao, Sridhar, Backman, Vadim, Bonini, Marcelo G.

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Identification of Transcribed Enhancers by Genome-Wide Chromatin Immunoprecipitation Sequencing von Blinka, Steven, Reimer, Michael H., Pulakanti, Kirthi, Pinello, Luca, Yuan, Guo-Cheng, Rao, Sridhar

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HNF4A Regulates the Formation of Hepatic Progenitor Cells from Human iPSC-Derived Endoderm by Facilitating Efficient Recruitment of RNA Pol II von DeLaForest, Ann, Di Furio, Francesca, Jing, Ran, Ludwig-Kubinski, Amy, Twaroski, Kirk, Urick, Amanda, Pulakanti, Kirthi, Rao, Sridhar, Duncan, Stephen A

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Downregulation of neurodevelopmental gene expression in iPSC-derived cerebral organoids upon infection by human cytomegalovirus von O’Brien, Benjamin S., Mokry, Rebekah L., Schumacher, Megan L., Pulakanti, Kirthi, Rao, Sridhar, Terhune, Scott S., Ebert, Allison D.

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Enhancer transcribed RNAs arise from hypomethylated, Tet-occupied genomic regions von Pulakanti, Kirthi, Pinello, Luca, Stelloh, Cary, Blinka, Steven, Allred, Jeremy, Milanovich, Samuel, Kiblawi, Sid, Peterson, Jonathan, Wang, Alexander, Yuan, Guo-Cheng, Rao, Sridhar

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Novel germline TRAF3IP3 mutation in a dyad with familial acute B lymphoblastic leukemia von Pommert, Lauren, Burns, Robert, Furumo, Quinlan, Pulakanti, Kirthi, Brandt, Jon, Burke, Michael J., Rao, Sridhar

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Cohesin Loss Dominantly Influences the Accessibility Landscape of Npm1cA/+ AML von Meyer, Alison E, Rao, Sid, Stelloh, Cary, Pulakanti, Kirthi

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The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing von Stelloh, Cary, Reimer, Michael H, Pulakanti, Kirthi, Blinka, Steven, Peterson, Jonathan, Pinello, Luca, Jia, Shuang, Roumiantsev, Sergei, Hessner, Martin J, Milanovich, Samuel, Yuan, Guo-Cheng, Rao, Sridhar

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Cohesin Haploinsufficiency Promotes Reduced Latency in Inv(16) Acute Myeloid Leukemia von Meyer, Alison E, Heimbruch, Katelyn, Stelloh, Cary, Pulakanti, Kirthi, Rao, Sridhar

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221: DEFINING THE ROLE OF GATA4 IN ESOPHAGEAL DISEASES von Franklin, Olivia D., Pulakanti, Kirthi, Rao, Sridhar, Pham, Thai, Wang, David, Battle, Michele A.

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A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis von Volk, Andrew, Liang, Kaiwei, Suraneni, Praveen, Li, Xinyu, Zhao, Jianyun, Bulic, Marinka, Marshall, Stacy, Pulakanti, Kirthi, Malinge, Sebastien, Taub, Jeffrey, Ge, Yubin, Rao, Sridhar, Bartom, Elizabeth, Shilatifard, Ali, Crispino, John D.

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Sa124 GATA4 SUPPRESSES STRATIFIED SQUAMOUS CELL IDENTITY AND PROMOTES COLUMNAR CELL GENE EXPRESSION IN PATIENT-DERIVED ESOPHAGEAL EPITHELIAL CELLS von Franklin, Olivia D., De La Forest, Ann, Stavniichuk, Roman, Pulakanti, Kirthi, Rao, Sridhar, Battle, Michele A.

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