P450-Catalyzed Regio- and Diastereoselective Steroid Hydroxylation: Efficient Directed Evolution Enabled by Mutability Landscaping von Acevedo-Rocha, Carlos G, Gamble, Charles G, Lonsdale, Richard, Li, Aitao, Nett, Nathalie, Hoebenreich, Sabrina, Lingnau, Julia B, Wirtz, Cornelia, Fares, Christophe, Hinrichs, Heike, Deege, Alfred, Mulholland, Adrian J, Nov, Yuval, Leys, David, McLean, Kirsty J, Munro, Andrew W, Reetz, Manfred T

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Indigenous peoples, local communities and climate change mitigation von Ramos-Castillo, Ameyali, Castellanos, Edwin J., Galloway McLean, Kirsty

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A Promiscuous Bacterial P450: The Unparalleled Diversity of BM3 in Pharmaceutical Metabolism von Thistlethwaite, Sian, Jeffreys, Laura N, Girvan, Hazel M, McLean, Kirsty J, Munro, Andrew W

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Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE (CYP152L1) from the Jeotgalicoccus sp. 8456 Bacterium von Belcher, James, McLean, Kirsty J., Matthews, Sarah, Woodward, Laura S., Fisher, Karl, Rigby, Stephen E.J., Nelson, David R., Potts, Donna, Baynham, Michael T., Parker, David A., Leys, David, Munro, Andrew W.

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Variations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily von Munro, Andrew W, Girvan, Hazel M, McLean, Kirsty J

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Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE von Matthews, Sarah, Belcher, James D., Tee, Kang Lan, Girvan, Hazel M., McLean, Kirsty J., Rigby, Stephen E.J., Levy, Colin W., Leys, David, Parker, David A., Blankley, Richard T., Munro, Andrew W.

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What makes a P450 tick? von Munro, Andrew W., Girvan, Hazel M., Mason, Amy E., Dunford, Adrian J., McLean, Kirsty J.

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Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum von McLean, Kirsty J, Hans, Marcus, Meijrink, Ben, van Scheppingen, Wibo B, Vollebregt, Aad, Tee, Kang Lan, van der Laan, Jan-Metske, Leys, David, Munro, Andrew W, van den Berg, Marco A

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Drug targeting of heme proteins in Mycobacterium tuberculosis von McLean, Kirsty J., Munro, Andrew W.

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Structural and Biochemical Characterization of Mycobacterium tuberculosis CYP142 von Driscoll, Max D., McLean, Kirsty J., Levy, Colin, Mast, Natalia, Pikuleva, Irina A., Lafite, Pierre, Rigby, Stephen E.J., Leys, David, Munro, Andrew W.

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Characterization of Active Site Structure in CYP121: A Cytochrome P450 Essential for Viability of Mycobacterium Tuberculosis H37Rv von McLean, Kirsty J., Carroll, Paul, Lewis, D. Geraint, Dunford, Adrian J., Seward, Harriet E., Neeli, Rajasekhar, Cheesman, Myles R., Marsollier, Laurent, Douglas, Philip, Smith, W. Ewen, Rosenkrands, Ida, Cole, Stewart T., Leys, David, Parish, Tanya, Munro, Andrew W.

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Application of Fragment Screening and Merging to the Discovery of Inhibitors of the Mycobacterium tuberculosis Cytochrome P450 CYP121 von Hudson, Sean A., McLean, Kirsty J., Surade, Sachin, Yang, Yong-Qing, Leys, David, Ciulli, Alessio, Munro, Andrew W., Abell, Chris

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Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis von Katariya, Mona M., Snee, Matthew, Tunnicliffe, Richard B., Kavanagh, Madeline E., Boshoff, Helena I. M., Amadi, Cecilia N., Levy, Colin W., Munro, Andrew W., Abell, Chris, Leys, David, Coyne, Anthony G., McLean, Kirsty J.

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Cytochrome P450–redox partner fusion enzymes von Munro, Andrew W., Girvan, Hazel M., McLean, Kirsty J.

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Effect of DMSO on Protein Structure and Interactions Assessed by Collision-Induced Dissociation and Unfolding von Chan, Daniel S.-H, Kavanagh, Madeline E, McLean, Kirsty J, Munro, Andrew. W, Matak-Vinković, Dijana, Coyne, Anthony G, Abell, Chris

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Computation-Aided Engineering of Cytochrome P450 for the Production of Pravastatin von Ashworth, Mark A., Bombino, Elvira, de Jong, René M., Wijma, Hein J., Janssen, Dick B., McLean, Kirsty J., Munro, Andrew W.

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Structure–Activity Relationships of cyclo(l‑Tyrosyl‑l‑tyrosine) Derivatives Binding to Mycobacterium tuberculosis CYP121: Iodinated Analogues Promote Shift to High-Spin Adduct... von Rajput, Sunnia, McLean, Kirsty J, Poddar, Harshwardhan, Selvam, Irwin R, Nagalingam, Gayathri, Triccas, James A, Levy, Colin W, Munro, Andrew W, Hutton, Craig A

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Evaluation of the priority primary care centre program to reduce emergency department burden in regional Victoria, Australia: a mixed-method study von Frith, Madison, Randall, Sean, Savira, Feby, Swann, Jamie, White, Naomi, Giddy, Andrew, McLean, Kirsty, Peeters, Anna, Robinson, Suzanne

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Structural characterization of CYP144A1 – a cytochrome P450 enzyme expressed from alternative transcripts in Mycobacterium tuberculosis von Chenge, Jude, Kavanagh, Madeline E., Driscoll, Max D., McLean, Kirsty J., Young, Douglas B., Cortes, Teresa, Matak-Vinkovic, Dijana, Levy, Colin W., Rigby, Stephen E. J., Leys, David, Abell, Chris, Munro, Andrew W.

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Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus von Girvan, Hazel M., Poddar, Harshwardhan, McLean, Kirsty J., Nelson, David R., Hollywood, Katherine A., Levy, Colin W., Leys, David, Munro, Andrew W.

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