Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps von Plé, Coline, Tam, Heng-Keat, Vieira Da Cruz, Anais, Compagne, Nina, Jiménez-Castellanos, Juan-Carlos, Müller, Reinke T., Pradel, Elizabeth, Foong, Wuen Ee, Malloci, Giuliano, Ballée, Alexia, Kirchner, Moritz A., Moshfegh, Parisa, Herledan, Adrien, Herrmann, Andrea, Deprez, Benoit, Willand, Nicolas, Vargiu, Attilio Vittorio, Pos, Klaas M., Flipo, Marion, Hartkoorn, Ruben C.

Volltext

Blik is an extensible 3D visualisation tool for the annotation and analysis of cryo-electron tomography data von Gaifas, Lorenzo, Kirchner, Moritz A, Timmins, Joanna, Gutsche, Irina

Volltext

Size matters: Dissecting key parameters for panel‐based tumor mutational burden analysis von Buchhalter, Ivo, Rempel, Eugen, Endris, Volker, Allgäuer, Michael, Neumann, Olaf, Volckmar, Anna‐Lena, Kirchner, Martina, Leichsenring, Jonas, Lier, Amelie, Winterfeld, Moritz, Penzel, Roland, Christopoulos, Petros, Thomas, Michael, Fröhling, Stefan, Schirmacher, Peter, Budczies, Jan, Stenzinger, Albrecht

Volltext

Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels von Endris, Volker, Buchhalter, Ivo, Allgäuer, Michael, Rempel, Eugen, Lier, Amelie, Volckmar, Anna‐Lena, Kirchner, Martina, Winterfeld, Moritz, Leichsenring, Jonas, Neumann, Olaf, Penzel, Roland, Weichert, Wilko, Glimm, Hanno, Fröhling, Stefan, Winter, Hauke, Herth, Felix, Thomas, Michael, Schirmacher, Peter, Budczies, Jan, Stenzinger, Albrecht

Volltext

gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis von Bollrath, Julia, Phesse, Toby J., von Burstin, Vivian A., Putoczki, Tracy, Bennecke, Moritz, Bateman, Trudie, Nebelsiek, Tim, Lundgren-May, Therese, Canli, Özge, Schwitalla, Sarah, Matthews, Vance, Schmid, Roland M., Kirchner, Thomas, Arkan, Melek C., Ernst, Matthias, Greten, Florian R.

Volltext

An analgesic pathway from parvocellular oxytocin neurons to the periaqueductal gray in rats von Iwasaki, Mai, Lefevre, Arthur, Althammer, Ferdinand, Clauss Creusot, Etienne, Łąpieś, Olga, Petitjean, Hugues, Hilfiger, Louis, Kerspern, Damien, Melchior, Meggane, Küppers, Stephanie, Krabichler, Quirin, Patwell, Ryan, Kania, Alan, Gruber, Tim, Kirchner, Matthew K., Wimmer, Moritz, Fröhlich, Henning, Dötsch, Laura, Schimmer, Jonas, Herpertz, Sabine C., Ditzen, Beate, Schaaf, Christian P., Schönig, Kai, Bartsch, Dusan, Gugula, Anna, Trenk, Aleksandra, Blasiak, Anna, Stern, Javier E., Darbon, Pascal, Grinevich, Valery, Charlet, Alexandre

Volltext

Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: Analysis of the first 3,000 Heidelberg cases von Volckmar, Anna‐Lena, Leichsenring, Jonas, Kirchner, Martina, Christopoulos, Petros, Neumann, Olaf, Budczies, Jan, Morais de Oliveira, Cristiano Manuel, Rempel, Eugen, Buchhalter, Ivo, Brandt, Regine, Allgäuer, Michael, Talla, Suranand Babu, von Winterfeld, Moritz, Herpel, Esther, Goeppert, Benjamin, Lier, Amelie, Winter, Hauke, Brummer, Tilman, Fröhling, Stefan, Faehling, Martin, Fischer, Jürgen R., Heußel, Claus Peter, Herth, Felix, Lasitschka, Felix, Schirmacher, Peter, Thomas, Michael, Endris, Volker, Penzel, Roland, Stenzinger, Albrecht

Volltext

Analysis of the hypothalamic oxytocin system and oxytocin receptor‐expressing astrocytes in a mouse model of Prader–Willi syndrome von Althammer, Ferdinand, Wimmer, Moritz Claudius, Krabichler, Quirin, Küppers, Stephanie, Schimmer, Jonas, Fröhlich, Henning, Dötsch, Laura, Gruber, Tim, Wunsch, Selina, Schubert, Tim, Kirchner, Matthew K., Stern, Javier E., Charlet, Alexandre, Grinevich, Valery, Schaaf, Christian P.

Volltext

Implementing tumor mutational burden (TMB) analysis in routine diagnostics—a primer for molecular pathologists and clinicians von Allgäuer, Michael, Budczies, Jan, Christopoulos, Petros, Endris, Volker, Lier, Amelie, Rempel, Eugen, Volckmar, Anna-Lena, Kirchner, Martina, von Winterfeld, Moritz, Leichsenring, Jonas, Neumann, Olaf, Fröhling, Stefan, Penzel, Roland, Thomas, Michael, Schirmacher, Peter, Stenzinger, Albrecht

Volltext

miRNA profiling of biliary intraepithelial neoplasia reveals stepwise tumorigenesis in distal cholangiocarcinoma via the miR‐451a/ATF2 axis von Loeffler, Moritz A, Hu, Jun, Kirchner, Martina, Wei, Xiyang, Xiao, Yi, Albrecht, Thomas, De La Torre, Carolina, Sticht, Carsten, Banales, Jesus M, Vogel, Monika N, Pathil‐Warth, Anita, Mehrabi, Arianeb, Hoffmann, Katrin, Rupp, Christian, Köhler, Bruno, Springfeld, Christoph, Schirmacher, Peter, Ji, Junfang, Roessler, Stephanie, Goeppert, Benjamin

Volltext

Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames von Sandmann, Clara-L., Schulz, Jana F., Ruiz-Orera, Jorge, Kirchner, Marieluise, Ziehm, Matthias, Adami, Eleonora, Marczenke, Maike, Christ, Annabel, Liebe, Nina, Greiner, Johannes, Schoenenberger, Aaron, Muecke, Michael B., Liang, Ning, Moritz, Robert L., Sun, Zhi, Deutsch, Eric W., Gotthardt, Michael, Mudge, Jonathan M., Prensner, John R., Willnow, Thomas E., Mertins, Philipp, van Heesch, Sebastiaan, Hubner, Norbert

Volltext

Spatial and Temporal Heterogeneity of Panel-Based Tumor Mutational Burden in Pulmonary Adenocarcinoma: Separating Biology From Technical Artifacts von Kazdal, Daniel, Endris, Volker, Allgäuer, Michael, Kriegsmann, Mark, Leichsenring, Jonas, Volckmar, Anna-Lena, Harms, Alexander, Kirchner, Martina, Kriegsmann, Katharina, Neumann, Olaf, Brandt, Regine, Talla, Suranand B., Rempel, Eugen, Ploeger, Carolin, von Winterfeld, Moritz, Christopoulos, Petros, Merino, Diana M., Stewart, Mark, Allen, Jeff, Bischoff, Helge, Meister, Michael, Muley, Thomas, Herth, Felix, Penzel, Roland, Warth, Arne, Winter, Hauke, Fröhling, Stefan, Peters, Solange, Swanton, Charles, Thomas, Michael, Schirmacher, Peter, Budczies, Jan, Stenzinger, Albrecht

Volltext

Ink4a/Arf and Oncogene-Induced Senescence Prevent Tumor Progression during Alternative Colorectal Tumorigenesis von Bennecke, Moritz, Kriegl, Lydia, Bajbouj, Monther, Retzlaff, Kristin, Robine, Sylvie, Jung, Andreas, Arkan, Melek C., Kirchner, Thomas, Greten, Florian R.

Volltext

Methodical Development of a Digital Twin for an Industry Valve von Koesters, Anton, Koetz, Florian, Bock, Moritz, Fett, Michel, Breimann, Richard, Kirchner, Eckhard

Volltext

Collagen I-based scaffolds negatively impact fracture healing in a mouse-osteotomy-model although used routinely in research and clinical application von Lang, Annemarie, Kirchner, Marieluise, Stefanowski, Jonathan, Durst, Mattea, Weber, Marie-Christin, Pfeiffenberger, Moritz, Damerau, Alexandra, Hauser, Anja E., Hoff, Paula, Duda, Georg N., Buttgereit, Frank, Schmidt-Bleek, Katharina, Gaber, Timo

Volltext

Polygenic analysis suggests the involvement of calcium signaling in executive function in schizophrenia patients von Kirchner, Sophie K., Ozkan, Selen, Musil, Richard, Spellmann, Ilja, Kannayian, Nirmal, Falkai, Peter, Rossner, Moritz, Papiol, Sergi

Volltext

System Design and Testing of the Hominid Robot Charlie von Kuehn, Daniel, Schilling, Moritz, Stark, Tobias, Zenzes, Martin, Kirchner, Frank

Volltext

SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis von Loevenich, Leon P, Tschurtschenthaler, Markus, Rokavec, Matjaz, Silva, Miguel G, Jesinghaus, Moritz, Kirchner, Thomas, Klauschen, Frederick, Saur, Dieter, Neumann, Jens, Hermeking, Heiko, Jung, Peter

Volltext

Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes von Musa, Julian, Cidre-Aranaz, Florencia, Aynaud, Marie-Ming, Orth, Martin F., Knott, Maximilian M. L., Mirabeau, Olivier, Mazor, Gal, Varon, Mor, Hölting, Tilman L. B., Grossetête, Sandrine, Gartlgruber, Moritz, Surdez, Didier, Gerke, Julia S., Ohmura, Shunya, Marchetto, Aruna, Dallmayer, Marlene, Baldauf, Michaela C., Stein, Stefanie, Sannino, Giuseppina, Li, Jing, Romero-Pérez, Laura, Westermann, Frank, Hartmann, Wolfgang, Dirksen, Uta, Gymrek, Melissa, Anderson, Nathaniel D., Shlien, Adam, Rotblat, Barak, Kirchner, Thomas, Delattre, Olivier, Grünewald, Thomas G. P.

Volltext

Effect of laser defocusing on duplex stainless steels for higher scan speeds in Laser-Based Powder Bed Fusion (PBF-LB/M) von Nahr, Florian, Bartels, Dominic, Schäfle, Moritz, Kirchner, Eckhard, Schmidt, Michael

Volltext