Transition states of native and drug-resistant HIV-1 protease are the same von Kipp, D. Randal, Hirschi, Jennifer S, Wakata, Aya, Goldstein, Harris, Schramm, Vern L

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Constrained Bonding Environment in the Michaelis Complex of Trypanosoma cruzi Uridine Phosphorylase von Silva, Rafael G, Kipp, D. Randal, Schramm, Vern L

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Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5 von Mavrakis, Konstantinos J., McDonald, E. Robert, Schlabach, Michael R., Billy, Eric, Hoffman, Gregory R., deWeck, Antoine, Ruddy, David A., Venkatesan, Kavitha, Yu, Jianjun, McAllister, Gregg, Stump, Mark, deBeaumont, Rosalie, Ho, Samuel, Yue, Yingzi, Liu, Yue, Yan-Neale, Yan, Yang, Guizhi, Lin, Fallon, Yin, Hong, Gao, Hui, Kipp, D. Randal, Zhao, Songping, McNamara, Joshua T., Sprague, Elizabeth R., Zheng, Bing, Lin, Ying, Cho, Young Shin, Gu, Justin, Crawford, Kenneth, Ciccone, David, Vitari, Alberto C., Lai, Albert, Capka, Vladimir, Hurov, Kristen, Porter, Jeffery A., Tallarico, John, Mickanin, Craig, Lees, Emma, Pagliarini, Raymond, Keen, Nicholas, Schmelzle, Tobias, Hofmann, Francesco, Stegmeier, Frank, Sellers, William R.

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Mass-Dependent Bond Vibrational Dynamics Influence Catalysis by HIV-1 Protease von Kipp, D. Randal, Silva, Rafael G, Schramm, Vern L

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Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors von Taylor, Alexander M., Williams, Bret R., Giordanetto, Fabrizio, Kelley, Elizabeth H., Lescarbeau, André, Shortsleeves, Kelley, Tang, Yong, Walters, W. Patrick, Arrazate, Alfonso, Bowman, Christine, Brophy, Erin, Chan, Emily W., Deshmukh, Gauri, Greisman, Jack B., Hunsaker, Thomas L., Kipp, D. Randal, Saenz Lopez-Larrocha, Pablo, Maddalo, Danilo, Martin, Iain J., Maragakis, Paul, Merchant, Mark, Murcko, Mark, Nisonoff, Hunter, Nguyen, Vi, Nguyen, Vy, Orozco, Olivia, Owen, Christopher, Pierce, Levi, Schmidt, Molly, Shaw, David E., Smith, Sherri, Therrien, Eric, Tran, John C., Watters, Jim, Waters, Nigel J., Wilbur, Jeremy, Willmore, Lindsay

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Suppression of in Vivo β-Amyloid Peptide Toxicity by Overexpression of the HSP-16.2 Small Chaperone Protein von Fonte, Virginia, Kipp, D. Randal, Yerg, John, Merin, David, Forrestal, Margaret, Wagner, Eileen, Roberts, Christine M., Link, Christopher D.

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Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia von Varkaris, Andreas, Pazolli, Ermira, Gunaydin, Hakan, Wang, Qi, Pierce, Levi, Boezio, Alessandro A, Bulku, Artemisa, DiPietro, Lucian, Fridrich, Cary, Frost, Adam, Giordanetto, Fabrizio, Hamilton, Erika P, Harris, Katherine, Holliday, Michael, Hunter, Tamieka L, Iskandar, Amanda, Ji, Yongli, Larivée, Alexandre, LaRochelle, Jonathan R, Lescarbeau, André, Llambi, Fabien, Lormil, Brenda, Mader, Mary M, Mar, Brenton G, Martin, Iain, McLean, Thomas H, Michelsen, Klaus, Pechersky, Yakov, Puente-Poushnejad, Erika, Raynor, Kevin, Rogala, Dipali, Samadani, Ramin, Schram, Alison M, Shortsleeves, Kelley, Swaminathan, Sweta, Tajmir, Shahein, Tan, Gege, Tang, Yong, Valverde, Roberto, Wehrenberg, Bryan, Wilbur, Jeremy, Williams, Bret R, Zeng, Hongtao, Zhang, Hanmo, Walters, W Patrick, Wolf, Beni B, Shaw, David E, Bergstrom, Donald A, Watters, James, Fraser, James S, Fortin, Pascal D, Kipp, D Randal

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Enzyme-Dependent Lysine Deprotonation in EZH2 Catalysis von Kipp, D. Randal, Quinn, Christopher M, Fortin, Pascal D

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The Novolactone Natural Product Disrupts the Allosteric Regulation of Hsp70 von Hassan, A. Quamrul, Kirby, Christina A., Zhou, Wenlai, Schuhmann, Tim, Kityk, Roman, Kipp, D. Randal, Baird, Jason, Chen, Jinyun, Chen, Yaoyu, Chung, Franklin, Hoepfner, Dominic, Movva, N. Rao, Pagliarini, Raymond, Petersen, Frank, Quinn, Christopher, Quinn, Douglas, Riedl, Ralph, Schmitt, Esther K., Schitter, Anne, Stams, Travis, Studer, Christian, Fortin, Pascal D., Mayer, Matthias P., Sadlish, Heather

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Suppression of in Vivo β-Amyloid Peptide Toxicity by Overexpression of the HSP-16.2 Small Chaperone Protein von Virginia Fonte, D. Randal Kipp, John Yerg III, David Merin, Margaret Forrestal, Eileen Wagner, Christine M. Roberts, Christopher D. Link

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The Novolactone Natural Product Disrupts the Allosteric Regulation of Hsp70 von Hassan, A. Quamrul, Kirby, Christina A., Zhou, Wenlai, Schuhmann, Tim, Kityk, Roman, Kipp, D. Randal, Baird, Jason, Chen, Jinyun, Chen, Yaoyu, Chung, Franklin, Hoepfner, Dominic, Movva, N. Rao, Pagliarini, Raymond, Petersen, Frank, Quinn, Christopher, Quinn, Douglas, Riedl, Ralph, Schmitt, Esther K., Schitter, Anne, Stams, Travis, Studer, Christian, Fortin, Pascal D., Mayer, Matthias P., Sadlish, Heather

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ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor von Mounir, Zineb, Korn, Joshua M, Westerling, Thomas, Lin, Fallon, Kirby, Christina A, Schirle, Markus, McAllister, Gregg, Hoffman, Greg, Ramadan, Nadire, Hartung, Anke, Feng, Yan, Kipp, David Randal, Quinn, Christopher, Fodor, Michelle, Baird, Jason, Schoumacher, Marie, Meyer, Ronald, Deeds, James, Buchwalter, Gilles, Stams, Travis, Keen, Nicholas, Sellers, William R, Brown, Myles, Pagliarini, Raymond A

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Metabolites produced by probiotic Lactobacilli rapidly increase glucose uptake by Caco-2 cells von Rooj, Arun K, Kimura, Yasuhiro, Buddington, Randal K

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Lumenal adenosine and AMP rapidly increase glucose transport by intact small intestine von Kimura, Yasuhiro, Turner, Jerrold R, Braasch, Dwaine A, Buddington, Randal K

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Glucose transport by epithelia prepared from harvested enterocytes von Kimura, Yasuhiro, van der Merwe, Marie, Bering, Stine B., Penmatsa, Himabindu, Conoley, Veronica G., Sangild, Per T., Naren, Anjaparavanda P., Buddington, Randal K.

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Reovirus therapy of lymphoid malignancies von Alain, Tommy, Hirasawa, Kensuke, Pon, Kelly J., Nishikawa, Sandra G., Urbanski, Stefan J., Auer, Yvonna, Luider, Joanne, Martin, Anita, Johnston, Randal N., Janowska-Wieczorek, Anna, Lee, PatrickW.K., Kossakowska, Anna E.

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Thank You to Our 2019 Peer Reviewers von Rajaram, Harihar, Camargo, Suzana, Carey, Rebecca, Corey, Rose M., Dombard, Andrew J., Donohue, Kathleen A., Flesch, Lucy, Giannini, Alessandra, Hayes, Gavin, Huber, Christian, Hogg, Andy M., Ivanov, Valeriy, Jacobsen, Steven D., Korte, Monika, Lu, Gang, Morlighem, Mathieu, Magnusdottir, Gudrun, Opher, Merav, Patricola, Christina M., Ritsema, Jeroen, Sprintall, Janet, Su, Hui, Thornton, Joel A., Trouet, Valerie, Wang, Kaicun, White, Angelicque E., Yau, Andrew

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Influence of 2-chlorodeoxyadenosine (cladribine) on human erythrocytes von Marczak, A., Łubgan, D., Robak, T., Jóźwiak, Z.

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Calorie restriction improves aging-induced impairment of cognitive function in relation to deregulation of corticosterone status and brain regional GABA system von Chakraborty, Apala, Banerjee, Soumyabrata, Mukherjee, Biswajit, Poddar, Mrinal Kanti

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MiR-29b Downregulates Canonical Wnt Signaling by Suppressing Coactivators of β-Catenin in Human Colorectal Cancer Cells von Subramanian, Maitreyi, Rao, Srinivasa R., Thacker, Pooja, Chatterjee, Suvro, Karunagaran, Devarajan

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