Shifting equilibriums in Alzheimer's disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis von Gray, Sophie, Kinghorn, Kerri, Woodling, Nathaniel

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Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis von Castillo-Quan, Jorge Iván, Li, Li, Kinghorn, Kerri J., Ivanov, Dobril K., Tain, Luke S., Slack, Cathy, Kerr, Fiona, Nespital, Tobias, Thornton, Janet, Hardy, John, Bjedov, Ivana, Partridge, Linda

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Lysosomal storage, impaired autophagy and innate immunity in Gaucher and Parkinson's diseases: insights for drug discovery von Hull, Alexander, Atilano, Magda L, Gergi, Laith, Kinghorn, Kerri J

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Autophagic dysfunction and gut microbiota dysbiosis cause chronic immune activation in a Drosophila model of Gaucher disease von Atilano, Magda L, Hull, Alexander, Romila, Catalina-Andreea, Adams, Mirjam L, Wildfire, Jacob, Ureña, Enric, Dyson, Miranda, Ivan-Castillo-Quan, Jorge, Partridge, Linda, Kinghorn, Kerri J

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Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila von Bjedov, Ivana, Cochemé, Helena M, Foley, Andrea, Wieser, Daniela, Woodling, Nathaniel S, Castillo-Quan, Jorge Iván, Norvaisas, Povilas, Lujan, Celia, Regan, Jennifer C, Toivonen, Janne M, Murphy, Michael P, Thornton, Janet, Kinghorn, Kerri J, Neufeld, Thomas P, Cabreiro, Filipe, Partridge, Linda

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A triple drug combination targeting components of the nutrient-sensing network maximizes longevity von Castillo-Quan, Jorge Iván, Tain, Luke S., Kinghorn, Kerri J., Li, Li, Grönke, Sebastian, Hinze, Yvonne, Blackwell, T. Keith, Bjedov, Ivana, Partridge, Linda

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A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin von Kinghorn, Kerri J, Grönke, Sebastian, Castillo-Quan, Jorge Iván, Woodling, Nathaniel S, Li, Li, Sirka, Ernestas, Gegg, Matthew, Mills, Kevin, Hardy, John, Bjedov, Ivana, Partridge, Linda

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Ceramide lowering rescues respiratory defects in a Drosophila model of acid sphingomyelinase deficiency von Hull, Alexander J, Atilano, Magda L, Hallqvist, Jenny, Heywood, Wendy, Kinghorn, Kerri J

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Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction von Kinghorn, Kerri J, Castillo-Quan, Jorge Iván, Bartolome, Fernando, Angelova, Plamena R, Li, Li, Pope, Simon, Cochemé, Helena M, Khan, Shabana, Asghari, Shabnam, Bhatia, Kailash P, Hardy, John, Abramov, Andrey Y, Partridge, Linda

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The emerging role of autophagic-lysosomal dysfunction in Gaucher disease and Parkinson's disease von Kinghorn, Kerri J, Asghari, Amir M, Castillo-Quan, Jorge Iván

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Agephagy - Adapting Autophagy for Health During Aging von Stead, Eleanor R, Castillo-Quan, Jorge I, Miguel, Victoria Eugenia Martinez, Lujan, Celia, Ketteler, Robin, Kinghorn, Kerri J, Bjedov, Ivana

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Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry von Deriziotis, Pelagia, André, Ralph, Smith, David M, Goold, Rob, Kinghorn, Kerri J, Kristiansen, Mark, Nathan, James A, Rosenzweig, Rina, Krutauz, Dasha, Glickman, Michael H, Collinge, John, Goldberg, Alfred L, Tabrizi, Sarah J

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Pathological looping in the synucleinopathies: investigating the link between Parkinson's disease and Gaucher disease von Kinghorn, Kerri J

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Autophagic dysregulation triggers innate immune activation in glucocerebrosidase deficiency von Atilano, Magda L., Hull, Alexander J., Kinghorn, Kerri J.

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Reply: Glial mitochondropathy in infantile neuroaxonal dystrophy: pathophysiological and therapeutic implications von Kinghorn, Kerri J, Castillo-Quan, Jorge Iván, Li, Li, Bhatia, Kailash P, Abramov, Andrey Y, Hardy, John, Partridge, Linda

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Mitochondrial dysfunction and defects in lipid homeostasis as therapeutic targets in neurodegeneration with brain iron accumulation von Kinghorn, Kerri J., Castillo-Quan, Jorge Iván

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Neuroserpin Binds Aβ and Is a Neuroprotective Component of Amyloid Plaques in Alzheimer Disease von Kinghorn, Kerri J., Crowther, Damian C., Sharp, Lynda K., Nerelius, Charlotte, Davis, Richard L., Chang, Howard T., Green, Clare, Gubb, David C., Johansson, Jan, Lomas, David A.

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Sugar and alcohol molecules provide a therapeutic strategy for the serpinopathies that cause dementia and cirrhosis von Sharp, Lynda K., Mallya, Meera, Kinghorn, Kerri J., Wang, Zhen, Crowther, Damian C., Huntington, James A., Belorgey, Didier, Lomas, David A.

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Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies von Crowther, Damian C, Belorgey, Didier, Miranda, Elena, Kinghorn, Kerri J, Sharp, Lynda K, Lomas, David A

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Autophagic dysfunction and gut microbiota dysbiosis cause chronic immune activation in a Drosophila model of Gaucher disease von Atilano, Magda L, Hull, Alexander, Romila, Catalina-Andreea, Adams, Mirjam L, Wildfire, Jacob, Urena, Enric, Dyson, Miranda, Ivan-Castillo-Quan, Jorge, Partridge, Linda, Kinghorn, Kerri J

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