Shifting equilibriums in Alzheimer's disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis von Gray, Sophie, Kinghorn, Kerri, Woodling, Nathaniel

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Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis von Castillo-Quan, Jorge Iván, Li, Li, Kinghorn, Kerri J., Ivanov, Dobril K., Tain, Luke S., Slack, Cathy, Kerr, Fiona, Nespital, Tobias, Thornton, Janet, Hardy, John, Bjedov, Ivana, Partridge, Linda

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Autophagic dysfunction and gut microbiota dysbiosis cause chronic immune activation in a Drosophila model of Gaucher disease von Atilano, Magda L, Hull, Alexander, Romila, Catalina-Andreea, Adams, Mirjam L, Wildfire, Jacob, Ureña, Enric, Dyson, Miranda, Ivan-Castillo-Quan, Jorge, Partridge, Linda, Kinghorn, Kerri J

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Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila von Bjedov, Ivana, Cochemé, Helena M, Foley, Andrea, Wieser, Daniela, Woodling, Nathaniel S, Castillo-Quan, Jorge Iván, Norvaisas, Povilas, Lujan, Celia, Regan, Jennifer C, Toivonen, Janne M, Murphy, Michael P, Thornton, Janet, Kinghorn, Kerri J, Neufeld, Thomas P, Cabreiro, Filipe, Partridge, Linda

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Resistin is expressed in human macrophages and directly regulated by PPARγ activators von Patel, Lisa, Buckels, Amy C, Kinghorn, Ian J, Murdock, Paul R, Holbrook, Joanna D, Plumpton, Christopher, Macphee, Colin H, Smith, Stephen A

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The emerging role of autophagic-lysosomal dysfunction in Gaucher disease and Parkinson's disease von Kinghorn, Kerri J, Asghari, Amir M, Castillo-Quan, Jorge Iván

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Lysosomal storage, impaired autophagy and innate immunity in Gaucher and Parkinson's diseases: insights for drug discovery von Hull, Alexander, Atilano, Magda L, Gergi, Laith, Kinghorn, Kerri J

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Agephagy - Adapting Autophagy for Health During Aging von Stead, Eleanor R, Castillo-Quan, Jorge I, Miguel, Victoria Eugenia Martinez, Lujan, Celia, Ketteler, Robin, Kinghorn, Kerri J, Bjedov, Ivana

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Autophagic dysregulation triggers innate immune activation in glucocerebrosidase deficiency von Atilano, Magda L., Hull, Alexander J., Kinghorn, Kerri J.

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A triple drug combination targeting components of the nutrient-sensing network maximizes longevity von Castillo-Quan, Jorge Iván, Tain, Luke S., Kinghorn, Kerri J., Li, Li, Grönke, Sebastian, Hinze, Yvonne, Blackwell, T. Keith, Bjedov, Ivana, Partridge, Linda

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A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin von Kinghorn, Kerri J, Grönke, Sebastian, Castillo-Quan, Jorge Iván, Woodling, Nathaniel S, Li, Li, Sirka, Ernestas, Gegg, Matthew, Mills, Kevin, Hardy, John, Bjedov, Ivana, Partridge, Linda

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Ceramide lowering rescues respiratory defects in a Drosophila model of acid sphingomyelinase deficiency von Hull, Alexander J, Atilano, Magda L, Hallqvist, Jenny, Heywood, Wendy, Kinghorn, Kerri J

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Pathological looping in the synucleinopathies: investigating the link between Parkinson's disease and Gaucher disease von Kinghorn, Kerri J

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Hypertrophic olivary degeneration on magnetic resonance imaging in mitochondrial syndromes associated with POLG and SURF1 mutations von Kinghorn, K. J., Kaliakatsos, M., Blakely, E. L., Taylor, R. W., Rich, P., Clarke, A., Omer, S.

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Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction von Kinghorn, Kerri J, Castillo-Quan, Jorge Iván, Bartolome, Fernando, Angelova, Plamena R, Li, Li, Pope, Simon, Cochemé, Helena M, Khan, Shabana, Asghari, Shabnam, Bhatia, Kailash P, Hardy, John, Abramov, Andrey Y, Partridge, Linda

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Dynamic capabilities, expert and entrepreneurial learning von Lecler, C. J, Kinghorn, J

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Squaric esters as peptide stapling reagents von Wayment, Adam X., Johnson, Nye C., Rodriguez Moreno, Mariur, Stewart, Christopher, Felix, Braxton M., Lambert, Isaac, Traynor, Sarah A., Michael Nielson, P., Lofgreen, Grant Q., Smith, Shannon L., Newton, Madison P., Tretbar, Jordan W., Nygaard, Joseph M.L., Harrell, Kylie G., Kinghorn, Michael J., Michaelis, David J.

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Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry von Deriziotis, Pelagia, André, Ralph, Smith, David M, Goold, Rob, Kinghorn, Kerri J, Kristiansen, Mark, Nathan, James A, Rosenzweig, Rina, Krutauz, Dasha, Glickman, Michael H, Collinge, John, Goldberg, Alfred L, Tabrizi, Sarah J

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Intraneuronal Aβ, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer’s disease von Crowther, D.C., Kinghorn, K.J., Miranda, E., Page, R., Curry, J.A., Duthie, F.A.I., Gubb, D.C., Lomas, D.A.

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Proximity-Induced Reactivity and Product Selectivity with a Rationally Designed Bifunctional Peptide Catalyst von Kinghorn, Michael J, Valdivia-Berroeta, Gabriel A, Chantry, Donalee R, Smith, Mason S, Ence, Chloe C, Draper, Steven R. E, Duval, Jared S, Masino, Bryan M, Cahoon, Samuel B, Flansburg, Rachael R, Conder, Cory J, Price, Joshua L, Michaelis, David J

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