Restoration of metabolic health by decreased consumption of branched‐chain amino acids von Cummings, Nicole E., Williams, Elizabeth M., Kasza, Ildiko, Konon, Elizabeth N., Schaid, Michael D., Schmidt, Brian A., Poudel, Chetan, Sherman, Dawn S., Yu, Deyang, Arriola Apelo, Sebastian I., Cottrell, Sara E., Geiger, Gabriella, Barnes, Macy E., Wisinski, Jaclyn A., Fenske, Rachel J., Matkowskyj, Kristina A., Kimple, Michelle E., Alexander, Caroline M., Merrins, Matthew J., Lamming, Dudley W.

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Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health von Fontana, Luigi, Cummings, Nicole E., Arriola Apelo, Sebastian I., Neuman, Joshua C., Kasza, Ildiko, Schmidt, Brian A., Cava, Edda, Spelta, Francesco, Tosti, Valeria, Syed, Faizan A., Baar, Emma L., Veronese, Nicola, Cottrell, Sara E., Fenske, Rachel J., Bertozzi, Beatrice, Brar, Harpreet K., Pietka, Terri, Bullock, Arnold D., Figenshau, Robert S., Andriole, Gerald L., Merrins, Matthew J., Alexander, Caroline M., Kimple, Michelle E., Lamming, Dudley W.

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A human pancreatic ECM hydrogel optimized for 3-D modeling of the islet microenvironment von Tremmel, Daniel M., Sackett, Sara Dutton, Feeney, Austin K., Mitchell, Samantha A., Schaid, Michael D., Polyak, Erzsebet, Chlebeck, Peter J., Gupta, Sakar, Kimple, Michelle E., Fernandez, Luis A., Odorico, Jon S.

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Effects of Arachidonic Acid and Its Metabolites on Functional Beta-Cell Mass von Bosma, Karin J, Kaiser, Cecilia E, Kimple, Michelle E, Gannon, Maureen

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Prostaglandin E2 Receptor, EP3, Is Induced in Diabetic Islets and Negatively Regulates Glucose- and Hormone-Stimulated Insulin Secretion von KIMPLE, Michelle E, KELLER, Mark P, RABAGLIA, Mary R, PASKER, Renee L, NEUMAN, Joshua C, TRUCHAN, Nathan A, BRAR, Harpreet K, ATTIE, Alan D

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Overview of Affinity Tags for Protein Purification von Kimple, Michelle E., Brill, Allison L., Pasker, Renee L.

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Opposing effects of prostaglandin E2 receptors EP3 and EP4 on mouse and human β-cell survival and proliferation von Carboneau, Bethany A, Allan, Jack A, Townsend, Shannon E, Kimple, Michelle E, Breyer, Richard M, Gannon, Maureen

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Plasma Prostaglandin E2 Metabolite Levels Predict Type 2 Diabetes Status and One-Year Therapeutic Response Independent of Clinical Markers of Inflammation von Fenske, Rachel J., Weeks, Alicia M., Daniels, Michael, Nall, Randall, Pabich, Samantha, Brill, Allison L., Peter, Darby C., Punt, Margaret, Cox, Elizabeth D., Davis, Dawn Belt, Kimple, Michelle E.

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Pharmacological blockade of the EP3 prostaglandin E2 receptor in the setting of type 2 diabetes enhances β-cell proliferation and identity and relieves oxidative damage von Bosma, Karin J., Andrei, Spencer R., Katz, Liora S., Smith, Ashley A., Dunn, Jennifer C., Ricciardi, Valerie F., Ramirez, Marisol A., Baumel-Alterzon, Sharon, Pace, William A., Carroll, Darian T., Overway, Emily M., Wolf, Elysa M., Kimple, Michelle E., Sheng, Quanhu, Scott, Donald K., Breyer, Richard M., Gannon, Maureen

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What the BTBR/J mouse has taught us about diabetes and diabetic complications von Keller, Mark P., Hudkins, Kelly L., Shalev, Anath, Bhatnagar, Sushant, Kebede, Melkam A., Merrins, Matthew J., Davis, Dawn Belt, Alpers, Charles E., Kimple, Michelle E., Attie, Alan D.

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Systemic Metabolic Alterations Correlate with Islet-Level Prostaglandin E2 Production and Signaling Mechanisms That Predict β-Cell Dysfunction in a Mouse Model of Type 2 Diabetes von Schaid, Michael D., Zhu, Yanlong, Richardson, Nicole E., Patibandla, Chinmai, Ong, Irene M., Fenske, Rachel J., Neuman, Joshua C., Guthery, Erin, Reuter, Austin, Sandhu, Harpreet K., Fuller, Miles H., Cox, Elizabeth D., Davis, Dawn B., Layden, Brian T., Brasier, Allan R., Lamming, Dudley W., Ge, Ying, Kimple, Michelle E.

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Differential Expression of Ormdl Genes in the Islets of Mice and Humans with Obesity von Lee, Hugo, Fenske, Rachel J., Akcan, Tugce, Domask, Elliot, Davis, Dawn B., Kimple, Michelle E., Engin, Feyza

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Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS‐1 (832/3) cell glucose‐stimulated insulin secretion von Sandhu, Harpreet K., Neuman, Joshua C., Schaid, Michael D., Davis, Sarah E., Connors, Kelsey M., Challa, Romith, Guthery, Erin, Fenske, Rachel J., Patibandla, Chinmai, Breyer, Richard M., Kimple, Michelle E.

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Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system von Arriola Apelo, Sebastian I., Neuman, Joshua C., Baar, Emma L., Syed, Faizan A., Cummings, Nicole E., Brar, Harpreet K., Pumper, Cassidy P., Kimple, Michelle E., Lamming, Dudley W.

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Short-term methionine deprivation improves metabolic health via sexually dimorphic, mTORC1-independent mechanisms von Yu, Deyang, Yang, Shany E, Miller, Blake R, Wisinski, Jaclyn A, Sherman, Dawn S, Brinkman, Jacqueline A, Tomasiewicz, Jay L, Cummings, Nicole E, Kimple, Michelle E, Cryns, Vincent L, Lamming, Dudley W

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Targeting dysfunctional beta-cell signaling for the potential treatment of type 1 diabetes mellitus von Fenske, Rachel J, Kimple, Michelle E

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Ultrahigh-Resolution Mass Spectrometry-Based Platform for Plasma Metabolomics Applied to Type 2 Diabetes Research von Zhu, Yanlong, Wancewicz, Benjamin, Schaid, Michael, Tiambeng, Timothy N, Wenger, Kent, Jin, Yutong, Heyman, Heino, Thompson, Christopher J, Barsch, Aiko, Cox, Elizabeth D, Davis, Dawn B, Brasier, Allan R, Kimple, Michelle E, Ge, Ying

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Metformin Monotherapy Alters the Human Plasma Lipidome Independent of Clinical Markers of Glycemic Control and Cardiovascular Disease Risk in a Type 2 Diabetes Clinical Cohort von Wancewicz, Benjamin, Zhu, Yanlong, Fenske, Rachel J, Weeks, Alicia M, Wenger, Kent, Pabich, Samantha, Daniels, Michael, Punt, Margaret, Nall, Randall, Peter, Darby C, Brasier, Allan, Cox, Elizabeth D, Davis, Dawn Belt, Ge, Ying, Kimple, Michelle E

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Prostaglandin EP3 receptor signaling is required to prevent insulin hypersecretion and metabolic dysfunction in a non-obese mouse model of insulin resistance von Wisinski, Jaclyn A, Reuter, Austin, Peter, Darby C, Schaid, Michael D, Fenske, Rachel J, Kimple, Michelle E

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Complement 1q-like-3 protein inhibits insulin secretion from pancreatic β-cells via the cell adhesion G protein–coupled receptor BAI3 von Gupta, Rajesh, Nguyen, Dan C., Schaid, Michael D., Lei, Xia, Balamurugan, Appakalai N., Wong, G. William, Kim, Jeong-a, Koltes, James E., Kimple, Michelle E., Bhatnagar, Sushant

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