Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab von Chin, S. Michael, Kimberlin, Christopher R., Roe-Zurz, Zygy, Zhang, Pamela, Xu, Allison, Liao-Chan, Sindy, Sen, Debasish, Nager, Andrew R., Oakdale, Nicole Schirle, Brown, Colleen, Wang, Feng, Yang, Yuting, Lindquist, Kevin, Yeung, Yik Andy, Salek-Ardakani, Shahram, Chaparro-Riggers, Javier

Volltext

Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression von Hastie, Kathryn M, Kimberlin, Christopher R, Zandonatti, Michelle A, MacRae, Ian J, Saphire, Erica Ollmann

Volltext

Structures of mouse and human GITR–GITRL complexes reveal unique TNF superfamily interactions von Wang, Feng, Chau, Bryant, West, Sean M., Kimberlin, Christopher R., Cao, Fei, Schwarz, Flavio, Aguilar, Barbara, Han, Minhua, Morishige, Winse, Bee, Christine, Dollinger, Gavin, Rajpal, Arvind, Strop, Pavel

Volltext

Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism von Bale, Shridhar, Julien, Jean-Philippe, Bornholdt, Zachary A, Kimberlin, Christopher R, Halfmann, Peter, Zandonatti, Michelle A, Kunert, John, Kroon, Gerard J A, Kawaoka, Yoshihiro, MacRae, Ian J, Wilson, Ian A, Saphire, Erica Ollmann

Volltext

Ebola Virus VP35 Protein Binds Double-Stranded RNA and Inhibits Alpha/Beta Interferon Production Induced by RIG-I Signaling von CARDENAS, Washington B, LOO, Yueh-Ming, GALE, Michael, HARTMAN, Amy L, KIMBERLIN, Christopher R, MARTINEZ-SOBRIDO, Luis, OLLMANN SAPHIRE, Erica, BASLER, Christopher F

Volltext

Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression von Kimberlin, Christopher R, Bornholdt, Zachary A, Li, Sheng, Woods, Virgil L. Jr, MacRae, Ian J, Saphire, Erica Ollmann

Volltext

A glutamate switch controls voltage-sensitive phosphatase function von Liu, Lijun, Kohout, Susy C, Xu, Qiang, Müller, Simone, Kimberlin, Christopher R, Isacoff, Ehud Y, Minor, Daniel L

Volltext

SARAF Luminal Domain Structure Reveals a Novel Domain-Swapped β-Sandwich Fold Important for SOCE Modulation von Kimberlin, Christopher R., Meshcheriakova, Anna, Palty, Raz, Raveh, Adi, Karbat, Izhar, Reuveny, Eitan, Minor, Daniel L.

Volltext

Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody von Al-Khami, Amir A., Youssef, Sawsan, Abdiche, Yasmina, Nguyen, HoangKim, Chou, Joyce, Kimberlin, Christopher R., Chin, Sherman M., Kamperschroer, Cris, Jessen, Bart, Kern, Brent, Budimir, Natalija, Dillon, Christopher P., Xu, Allison, Clark, Jerry D., Chou, Jeffrey, Kraynov, Eugenia, Rajpal, Arvind, Lin, John C., Salek-Ardakani, Shahram

Volltext

737 A PHASE-I, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS OF SINGLE ESCALATING ORAL DOSES OF GS-... von Lopatin, U, Wolfgang, G, Kimberlin, R, Turnas, D, Cornprost, M, Chittick, G, Frey, C, Findlay, J, Ohmstede, C, Kearney, B, Barnes, C, McHutchinson, J, Hirsch, K

Volltext

Studies of the transmissibility of the agent of bovine spongiform encephalopathy to pigs von Wells, Gerald A. H, Hawkins, Stephen A. C, Austin, Anthony R, Ryder, Stephen J, Done, Stanley H, Green, Robert B, Dexter, Ian, Dawson, Michael, Kimberlin, Richard H

Volltext

genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice von Kimberlin, R.H, Walker, C.A, Fraser, H

Volltext

Hiding the evidence: two strategies for innate immune evasion by hemorrhagic fever viruses von Hastie, Kathryn M, Bale, Shridhar, Kimberlin, Christopher R, Saphire, Erica Ollmann

Volltext

Creutzfeldt-Jakob Disease and the Risk from Blood or Blood Products von Will, R. G., Kimberlin, R. H.

Volltext

Temporary and permanent modifications to a single strain of mouse scrapie on transmission to rats and hamsters von Kimberlin, R.H, Cole, S, Walker, C.A

Volltext

The major polypeptide of scrapie‐associated fibrils (SAF) has the same size, charge distribution and N‐terminal protein sequence as predicted for the normal brain protein (PrP) von Hope, J., Morton, L.J., Farquhar, C.F., Multhaup, G., Beyreuther, K., Kimberlin, R.H.

Volltext

Novel Growth of Ag Islands on Si(111): Plateaus with a Singular Height von Gavioli, Luca, Kimberlin, Kevin R., Tringides, Michael C., Wendelken, John F., Zhang, Zhenyu

Volltext

Pathogenesis of scrapie (strain 263K) in hamsters infected intracerebrally, intraperitoneally or intraocularly von Kimberlin, R.H, Walker, C.A

Volltext

Pathogenesis of scrapie in mice after intragastric infection von Kimberlin, Richard H., Walker, Carol A.

Volltext

Scrapie infectivity, fibrils and low molecular weight protein von Diringer, H, Gelderblom, H, Hilmert, H, Ozel, M, Edelbluth, C

Volltext