Automated cellular annotation for high-resolution images of adult Caenorhabditis elegans von Aerni, Sarah J, Liu, Xiao, Do, Chuong B, Gross, Samuel S, Nguyen, Andy, Guo, Stephen D, Long, Fuhui, Peng, Hanchuan, Kim, Stuart S, Batzoglou, Serafim

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Altered levels of mitochondrial DNA are associated with female age, aneuploidy, and provide an independent measure of embryonic implantation potential von Fragouli, Elpida, Spath, Katharina, Alfarawati, Samer, Kaper, Fiona, Craig, Andrew, Michel, Claude-Edouard, Kokocinski, Felix, Cohen, Jacques, Munne, Santiago, Wells, Dagan

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Intestinal Autophagy Improves Healthspan and Longevity in C. elegans during Dietary Restriction von Gelino, Sara, Chang, Jessica T, Kumsta, Caroline, She, Xingyu, Davis, Andrew, Nguyen, Christian, Panowski, Siler, Hansen, Malene

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Mitochondrial and cytoplasmic ROS have opposing effects on lifespan von Schaar, Claire E, Dues, Dylan J, Spielbauer, Katie K, Machiela, Emily, Cooper, Jason F, Senchuk, Megan, Hekimi, Siegfried, Van Raamsdonk, Jeremy M

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Lifespan extension by methionine restriction requires autophagy-dependent vacuolar acidification von Ruckenstuhl, Christoph, Netzberger, Christine, Entfellner, Iryna, Carmona-Gutierrez, Didac, Kickenweiz, Thomas, Stekovic, Slaven, Gleixner, Christina, Schmid, Christian, Klug, Lisa, Sorgo, Alice G, Eisenberg, Tobias, Büttner, Sabrina, Mariño, Guillermo, Koziel, Rafal, Jansen-Dürr, Pidder, Fröhlich, Kai-Uwe, Kroemer, Guido, Madeo, Frank

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New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen von Hansen, Malene, Hsu, Ao-Lin, Dillin, Andrew, Kenyon, Cynthia

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A global survey of gene regulation during cold acclimation in Arabidopsis thaliana von Hannah, Matthew A, Heyer, Arnd G, Hincha, Dirk K

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Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis von Larson, Kimberly, Yan, Shian-Jang, Tsurumi, Amy, Liu, Jacqueline, Zhou, Jun, Gaur, Kriti, Guo, Dongdong, Eickbush, Thomas H, Li, Willis X

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A role for autophagy in the extension of lifespan by dietary restriction in C. elegans von Hansen, Malene, Chandra, Abha, Mitic, Laura L, Onken, Brian, Driscoll, Monica, Kenyon, Cynthia

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Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans von Van Raamsdonk, Jeremy M, Hekimi, Siegfried

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Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae von Kruegel, Undine, Robison, Brett, Dange, Thomas, Kahlert, Günther, Delaney, Joe R, Kotireddy, Soumya, Tsuchiya, Mitsuhiro, Tsuchiyama, Scott, Murakami, Christopher J, Schleit, Jennifer, Sutphin, George, Carr, Daniel, Tar, Krisztina, Dittmar, Gunnar, Kaeberlein, Matt, Kennedy, Brian K, Schmidt, Marion

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Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD von Böger, Carsten A, Gorski, Mathias, Li, Man, Hoffmann, Michael M, Huang, Chunmei, Yang, Qiong, Teumer, Alexander, Krane, Vera, O'Seaghdha, Conall M, Kutalik, Zoltán, Wichmann, H-Erich, Haak, Thomas, Boes, Eva, Coassin, Stefan, Coresh, Josef, Kollerits, Barbara, Haun, Margot, Paulweber, Bernhard, Köttgen, Anna, Li, Guo, Shlipak, Michael G, Powe, Neil, Hwang, Shih-Jen, Dehghan, Abbas, Rivadeneira, Fernando, Uitterlinden, André, Hofman, Albert, Beckmann, Jacques S, Krämer, Bernhard K, Witteman, Jacqueline, Bochud, Murielle, Siscovick, David, Rettig, Rainer, Kronenberg, Florian, Wanner, Christoph, Thadhani, Ravi I, Heid, Iris M, Fox, Caroline S, Kao, W H

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MicroRNA predictors of longevity in Caenorhabditis elegans von Pincus, Zachary, Smith-Vikos, Thalyana, Slack, Frank J

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C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging von van Ham, Tjakko J, Thijssen, Karen L, Breitling, Rainer, Hofstra, Robert M W, Plasterk, Ronald H A, Nollen, Ellen A A

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Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9 von Wei, Min, Fabrizio, Paola, Hu, Jia, Ge, Huanying, Cheng, Chao, Li, Lei, Longo, Valter D

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Whole-genome cartography of estrogen receptor alpha binding sites von Lin, Chin-Yo, Vega, Vinsensius B, Thomsen, Jane S, Zhang, Tao, Kong, Say Li, Xie, Min, Chiu, Kuo Ping, Lipovich, Leonard, Barnett, Daniel H, Stossi, Fabio, Yeo, Ailing, George, Joshy, Kuznetsov, Vladimir A, Lee, Yew Kok, Charn, Tze Howe, Palanisamy, Nallasivam, Miller, Lance D, Cheung, Edwin, Katzenellenbogen, Benita S, Ruan, Yijun, Bourque, Guillaume, Wei, Chia-Lin, Liu, Edison T

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Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans von Shen, Xiaohua, Ellis, Ronald E, Sakaki, Kenjiro, Kaufman, Randal J

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A microarray-based genetic screen for yeast chronological aging factors von Matecic, Mirela, Smith, Daniel L, Pan, Xuewen, Maqani, Nazif, Bekiranov, Stefan, Boeke, Jef D, Smith, Jeffrey S

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Lifespan regulation by evolutionarily conserved genes essential for viability von Curran, Sean P, Ruvkun, Gary

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Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism von Palian, Beth M, Rohira, Aarti D, Johnson, Sandra A S, He, Lina, Zheng, Ni, Dubeau, Louis, Stiles, Bangyan L, Johnson, Deborah L

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