Evolution of chimeric antigen receptor (CAR) T cell therapy: current status and future perspectives von Lee, Young-Ho, Kim, Chan Hyuk

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Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies von Rodgers, David T., Mazagova, Magdalena, Hampton, Eric N., Cao, Yu, Ramadoss, Nitya S., Hardy, Ian R., Schulman, Andrew, Du, Juanjuan, Wang, Feng, Singer, Oded, Ma, Jennifer, Nunez, Vanessa, Shen, Jiayin, Woods, Ashley K., Wright, Timothy M., Schultz, Peter G., Kim, Chan Hyuk, Young, Travis S.

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Versatile strategy for controlling the specificity and activity of engineered T cells von Ma, Jennifer S. Y., Kim, Ji Young, Kazane, Stephanie A., Choi, Sei-hyun, Yun, Hwa Young, Kim, Min Soo, Rodgers, David T., Pugh, Holly M., Singer, Oded, Sun, Sophie B., Fonslow, Bryan R., Kochenderfer, James N., Wright, Timothy M., Schultz, Peter G., Young, Travis S., Kim, Chan Hyuk, Cao, Yu

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Deep-learning-based three-dimensional label-free tracking and analysis of immunological synapses of CAR-T cells von Lee, Moosung, Lee, Young-Ho, Song, Jinyeop, Kim, Geon, Jo, YoungJu, Min, HyunSeok, Kim, Chan Hyuk, Park, YongKeun

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Synthesis of site-specific antibody-drug conjugates using unnatural amino acids von Axup, Jun Y, Bajjuri, Krishna M, Ritland, Melissa, Hutchins, Benjamin M, Kim, Chan Hyuk, Kazane, Stephanie A, Halder, Rajkumar, Forsyth, Jane S, Santidrian, Antonio F, Stafin, Karin, Lu, Yingchun, Tran, Hon, Seller, Aaron J, Biroc, Sandra L, Szydlik, Aga, Pinkstaff, Jason K, Tian, Feng, Sinha, Subhash C, Felding-Habermann, Brunhilde, Smider, Vaughn V, Schultz, Peter G

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Synthesis of Bispecific Antibodies using Genetically Encoded Unnatural Amino Acids von Kim, Chan Hyuk, Axup, Jun Y, Dubrovska, Anna, Kazane, Stephanie A, Hutchins, Benjamin A, Wold, Erik D, Smider, Vaughn V, Schultz, Peter G

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Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer von Cao, Yu, Rodgers, David T., Du, Juanjuan, Ahmad, Insha, Hampton, Eric N., Ma, Jennifer S. Y., Mazagova, Magdalena, Choi, Sei-hyun, Yun, Hwa Young, Xiao, Han, Yang, Pengyu, Luo, Xiaozhou, Lim, Reyna K. V., Pugh, Holly M., Wang, Feng, Kazane, Stephanie A., Wright, Timothy M., Kim, Chan Hyuk, Schultz, Peter G., Young, Travis S.

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A Genetically Encoded aza-Michael Acceptor for Covalent Cross-Linking of Protein–Receptor Complexes von Furman, Jennifer L, Kang, Mingchao, Choi, Seihyun, Cao, Yu, Wold, Erik D, Sun, Sophie B, Smider, Vaughn V, Schultz, Peter G, Kim, Chan Hyuk

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Therapeutic Applications of an Expanded Genetic Code von Sun, Sophie B., Schultz, Peter G., Kim, Chan Hyuk

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Reprogramming of IL-12 secretion in the PDCD1 locus improves the anti-tumor activity of NY-ESO-1 TCR-T cells von Kim, Segi, Park, Cho I, Lee, Sunhwa, Choi, Hyeong Ryeol, Kim, Chan Hyuk

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Targeting Human C-Type Lectin-like Molecule-1 (CLL1) with a Bispecific Antibody for Immunotherapy of Acute Myeloid Leukemia von Lu, Hua, Zhou, Quan, Deshmukh, Vishal, Phull, Hardeep, Ma, Jennifer, Tardif, Virginie, Naik, Rahul R., Bouvard, Claire, Zhang, Yong, Choi, Seihyun, Lawson, Brian R., Zhu, Shoutian, Kim, Chan Hyuk, Schultz, Peter G.

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Development of A Chimeric Antigen Receptor Targeting C-Type Lectin-Like Molecule-1 for Human Acute Myeloid Leukemia von Laborda, Eduardo, Mazagova, Magdalena, Shao, Sida, Wang, Xinxin, Quirino, Herlinda, Woods, Ashley K, Hampton, Eric N, Rodgers, David T, Kim, Chan Hyuk, Schultz, Peter G, Young, Travis S

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Bispecific small molecule–antibody conjugate targeting prostate cancer von Kim, Chan Hyuk, Axup, Jun Y., Lawson, Brian R., Yun, Hwayoung, Tardif, Virginie, Choi, Sei Hyun, Zhou, Quan, Dubrovska, Anna, Biroc, Sandra L., Marsden, Robin, Pinstaff, Jason, Smider, Vaughn V., Schultz, Peter G.

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Dual Unnatural Amino Acid Incorporation and Click-Chemistry Labeling to Enable Single-Molecule FRET Studies of p97 Folding von Lee, Taehyung C., Kang, Minjin, Kim, Chan Hyuk, Schultz, Peter G., Chapman, Eli, Deniz, Ashok A.

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Carbonyl Ylide Cycloaddition Approach to Platensimycin von Kim, Chan Hyuk, Jang, Ki Po, Choi, Soo Young, Chung, Young Keun, Lee, Eun

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Engineering Bifunctional Antibodies with Constant Region Fusion Architectures von Du, Juanjuan, Cao, Yu, Liu, Yan, Wang, Ying, Zhang, Yong, Fu, Guangsen, Zhang, Yuhan, Lu, Lucy, Luo, Xiaozhou, Kim, Chan Hyuk, Schultz, Peter G, Wang, Feng

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Stereoselective Synthesis of (−)-Amphidinolide E von Kim, Chan Hyuk, An, Hyo Jung, Shin, Won Kyo, Yu, Wei, Woo, Sang Kook, Jung, Soon Kyu, Lee, Eun

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Multiformat T-Cell-Engaging Bispecific Antibodies Targeting Human Breast Cancers von Cao, Yu, Axup, Jun Y., Ma, Jennifer S. Y., Wang, Rongsheng E., Choi, Seihyun, Tardif, Virginie, Lim, Reyna K. V., Pugh, Holly M., Lawson, Brian R., Welzel, Gus, Kazane, Stephanie A., Sun, Ying, Tian, Feng, Srinagesh, Shailaja, Javahishvili, Tsotne, Schultz, Peter G., Kim, Chan Hyuk

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Engineering second-generation TCR-T cells by site-specific integration of TRAF-binding motifs into the CD247 locus von Lah, Sangjoon, Kim, Segi, Kang, In, Kim, Hyojin, Hupperetz, Cedric, Jung, Hyuncheol, Choi, Hyeong Ryeol, Lee, Young-Ho, Jang, Hyeon-Ki, Bae, Sangsu, Kim, Chan Hyuk

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Recruiting Cytotoxic T Cells to Folate-Receptor-Positive Cancer Cells von Kularatne, Sumith A., Deshmukh, Vishal, Gymnopoulos, Marco, Biroc, Sandra L., Xia, Jinming, Srinagesh, Shailaja, Sun, Ying, Zou, Ning, Shimazu, Mark, Pinkstaff, Jason, Ensari, Semsi, Knudsen, Nick, Manibusan, Anthony, Axup, Jun Y., Kim, Chan Hyuk, Smider, Vaughn V., Javahishvili, Tsotne, Schultz, Peter G.

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