DPYD genotype-guided dose individualization of fluoropyrimidine therapy: A prospective safety and cost-analysis on DPYD variants DPYD2A, c.2846A>T, c.1679T>G and c.1236G>A von Henricks, L M, Lunenburg, C A T C, de Man, F M, Meulendijks, D, Frederix, G W J, Kienhuis, E, Creemers, G-J M, Baars, A, Dezentjé, V O, Rosing, H, Beijnen, J H, van Werkhoven, E, van Kuilenburg, A B P, van Schaik, R H N, Mathijssen, R H J, Swen, J J, Gelderblom, H, Cats, A, Guchelaar, H-J, Schellens, J H M

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3059 Influence of an acidic beverage (Coca-Cola) on the absorption of erlotinib: Results of a cross-over study in NSCLC patients von Van Leeuwen, R, Peric, R, Hussaarts, K, Kienhuis, E, IJzerman, N, Bruijn, P. De, Van der Leest, K, Codrington, H, Kloover, J, Van der Holt, B, Aerts, J, Van Gelder, T, Mathijssen, R

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452ODPYD genotype-guided dose individualization of fluoropyrimidine therapy: A prospective safety and cost-analysis on DPYD variants DPYD2A, c.2846A>T, c.1679T>G and c.1236G>A von Henricks, L M, Lunenburg, C A T C, de Man, F M, Meulendijks, D, Frederix, G W J, Kienhuis, E, Creemers, G-J M, Baars, A, Dezentjé, V O, Rosing, H, Beijnen, J H, van Werkhoven, E, van Kuilenburg, A B P, van Schaik, R H N, Mathijssen, R H J, Swen, J J, Gelderblom, H, Cats, A, Guchelaar, H-J, Schellens, J H M

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A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy von Henricks, L.M., Lunenburg, C.A.T.C., Man, F.M. de, Meulendijks, D., Frederix, G.W.J., Kienhuis, E., Creemers, G.J., Baars, A., Dezentjé, V.O., Imholz, A.L.T., Jeurissen, F.J.F., Portielje, J.E.A., Jansen, R.L.H., Hamberg, P., Tije, A.J. ten, Droogendijk, H.J., Koopman, M., Nieboer, P., Poel, M.H.W. van de, Mandigers, C.M.P.W., Rosing, H., Beijnen, J.H., Werkhoven, E. van, Kuilenburg, A.B.P. van, Schaik, R.H.N. van, Mathijssen, R.H.J., Swen, J.J., Gelderblom, H., Cats, A., Guchelaar, H.J., Schellens, J.H.M.

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Conversion of Mature Human β-Cells Into Glucagon-Producing α-Cells von SIEBE SPIJKER, H, RAVELLI, Raimond B. G, MUMMERY, Christine L, CARLOTTI, Françoise, DE KONING, Eelco J. P, MIEKE MOMMAAS-KIENHUIS, A, VAN APELDOORN, Aart A, ENGELSE, Marten A, ZALDUMBIDE, Arnaud, BONNER-WEIR, Susan, RABELINK, Ton J, HOEBEN, Rob C, CLEVERS, Hans

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Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance von Lin, Jing-Wen, Spaccapelo, Roberta, Schwarzer, Evelin, Sajid, Mohammed, Annoura, Takeshi, Deroost, Katrien, Ravelli, Raimond B G, Aime, Elena, Capuccini, Barbara, Mommaas-Kienhuis, Anna M, O'Toole, Tom, Prins, Frans, Franke-Fayard, Blandine M D, Ramesar, Jai, Chevalley-Maurel, Séverine, Kroeze, Hans, Koster, Abraham J, Tanke, Hans J, Crisanti, Andrea, Langhorne, Jean, Arese, Paolo, Van den Steen, Philippe E, Janse, Chris J, Khan, Shahid M

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Exploring the zebrafish embryo as an alternative model for the evaluation of liver toxicity by histopathology and expression profiling von Driessen, Marja, Kienhuis, Anne S., Pennings, Jeroen L. A., Pronk, Tessa E., van de Brandhof, Evert-Jan, Roodbergen, Marianne, Spaink, Herman P., van de Water, Bob, van der Ven, Leo T. M.

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Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis von Kienhuis, Anne S., Vitins, Alexa P., Pennings, Jeroen L.A., Pronk, Tessa E., Speksnijder, Ewoud N., Roodbergen, Marianne, van Delft, Joost H.M., Luijten, Mirjam, van der Ven, Leo T.M.

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Gene expression markers in the zebrafish embryo reflect a hepatotoxic response in animal models and humans von Driessen, Marja, Kienhuis, Anne S., Vitins, Alexa P., Pennings, Jeroen L.A., Pronk, Tessa E., Brandhof, Evert-Jan van den, Roodbergen, Marianne, Water, Bob van de, Ven, Leo T.M.van der

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The Rise of Three Rs Centres and Platforms in Europe von Neuhaus, Winfried, Reininger-Gutmann, Birgit, Rinner, Beate, Plasenzotti, Roberto, Wilflingseder, Doris, De Kock, Joery, Vanhaecke, Tamara, Rogiers, Vera, Jírová, Dagmar, Kejlová, Kristina, Knudsen, Lisbeth E., Nielsen, Rasmus Normann, Kleuser, Burkhard, Kral, Vivian, Thöne-Reineke, Christa, Hartung, Thomas, Pallocca, Giorgia, Leist, Marcel, Hippenstiel, Stefan, Lang, Annemarie, Retter, Ida, Krämer, Stephanie, Jedlicka, Peter, Ameli, Katharina, Fritsche, Ellen, Tigges, Julia, Buettner, Manuela, Bleich, Andre, Baumgart, Nadine, Baumgart, Jan, Meinhardt, Marcus W., Spanagel, Rainer, Chourbaji, Sabine, Kränzlin, Bettina, Seeger, Bettina, von Köckritz-Blickwede, Maren, Sánchez-Morgado, José M., Galligioni, Viola, Ruiz-Pérez, Daniel, Movia, Dania, Prina-Mello, Adriele, Ahluwalia, Arti, Chiono, Valeria, Gutleb, Arno C., Schmit, Marthe, van Golen, Bea, van Weereld, Leane, Kienhuis, Anne, van Oort, Erica, van der Valk, Jan, Smith, Adrian, Roszak, Joanna, Stępnik, Maciej, Sobańska, Zuzanna, Olsson, I. Anna S., Franco, Nuno Henrique, Sevastre, Bogdan, Kandarova, Helena, Capdevila, Sara, Johansson, Jessica, Cederroth, Christopher R., Sandström, Jenny, Ragan, Ian, Bubalo, Nataliia, Spielmann, Horst

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Application of toxicogenomics in hepatic systems toxicology for risk assessment: Acetaminophen as a case study von Kienhuis, Anne S., Bessems, Jos G.M., Pennings, Jeroen L.A., Driessen, Marja, Luijten, Mirjam, van Delft, Joost H.M., Peijnenburg, Ad A.C.M., der Ven, Leo T.M. van

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The Current Status and Work of Three Rs Centres and Platforms in Europe von Neuhaus, Winfried, Reininger-Gutmann, Birgit, Rinner, Beate, Plasenzotti, Roberto, Wilflingseder, Doris, De Kock, Joery, Vanhaecke, Tamara, Rogiers, Vera, Jírová, Dagmar, Kejlová, Kristina, Knudsen, Lisbeth E., Nielsen, Rasmus Normann, Kleuser, Burkhard, Kral, Vivian, Thöne-Reineke, Christa, Hartung, Thomas, Pallocca, Giorgia, Rovida, Costanza, Leist, Marcel, Hippenstiel, Stefan, Lang, Annemarie, Retter, Ida, Krämer, Stephanie, Jedlicka, Peter, Ameli, Katharina, Fritsche, Ellen, Tigges, Julia, Kuchovská, Eliška, Buettner, Manuela, Bleich, Andre, Baumgart, Nadine, Baumgart, Jan, Meinhardt, Marcus W., Spanagel, Rainer, Chourbaji, Sabine, Kränzlin, Bettina, Seeger, Bettina, von Köckritz-Blickwede, Maren, Sánchez-Morgado, José M., Galligioni, Viola, Ruiz-Pérez, Daniel, Movia, Dania, Prina-Mello, Adriele, Ahluwalia, Arti, Chiono, Valeria, Gutleb, Arno C., Schmit, Marthe, van Golen, Bea, van Weereld, Leane, Kienhuis, Anne, van Oort, Erica, van der Valk, Jan, Smith, Adrian, Roszak, Joanna, Stępnik, Maciej, Sobańska, Zuzanna, Reszka, Edyta, Olsson, I. Anna S., Franco, Nuno Henrique, Sevastre, Bogdan, Kandarova, Helena, Capdevila, Sara, Johansson, Jessica, Svensk, Emma, Cederroth, Christopher R., Sandström, Jenny, Ragan, Ian, Bubalo, Nataliia, Kurreck, Jens, Spielmann, Horst

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Improved analysis of ladderane lipids in biomass and sediments using high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry von Hopmans, Ellen C., Kienhuis, Michiel V. M., Rattray, Jayne E., Jaeschke, Andrea, Schouten, Stefan, Damsté, Jaap S. Sinninghe

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Parameterized Looped Schedules for Compact Representation of Execution Sequences in DSP Hardware and Software Implementation von Ming-Yung Ko, Zissulescu, C., Puthenpurayil, S., Bhattacharyya, S.S., Kienhuis, B., Deprettere, E.F.

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A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy von Henricks, Linda M, Lunenburg, Carin A T C, de Man, Femke M, Meulendijks, Didier, Frederix, Geert W J, Kienhuis, Emma, Creemers, Geert-Jan, Baars, Arnold, Dezentjé, Vincent O, Imholz, Alexander L T, Jeurissen, Frank J F, Portielje, Johanna E A, Jansen, Rob L H, Hamberg, Paul, Ten Tije, Albert J, Droogendijk, Helga J, Koopman, Miriam, Nieboer, Peter, van de Poel, Marlène H W, Mandigers, Caroline M P W, Rosing, Hilde, Beijnen, Jos H, van Werkhoven, Erik, van Kuilenburg, André B P, van Schaik, Ron H N, Mathijssen, Ron H J, Swen, Jesse J, Gelderblom, Hans, Cats, Annemieke, Guchelaar, Henk-Jan, Schellens, Jan H M

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DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis von Henricks, Linda M, Lunenburg, Carin A T C, de Man, Femke M, Meulendijks, Didier, Frederix, Geert W J, Kienhuis, Emma, Creemers, Geert-Jan, Baars, Arnold, Dezentjé, Vincent O, Imholz, Alexander L T, Jeurissen, Frank J F, Portielje, Johanna E A, Jansen, Rob L H, Hamberg, Paul, Ten Tije, Albert J, Droogendijk, Helga J, Koopman, Miriam, Nieboer, Peter, van de Poel, Marlène H W, Mandigers, Caroline M P W, Rosing, Hilde, Beijnen, Jos H, Werkhoven, Erik van, van Kuilenburg, André B P, van Schaik, Ron H N, Mathijssen, Ron H J, Swen, Jesse J, Gelderblom, Hans, Cats, Annemieke, Guchelaar, Henk-Jan, Schellens, Jan H M

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Vegetables Affect the Expression of Genes Involved in Anticarcinogenic Processes in the Colonic Mucosa of C57Bl/6 Female Mice von van Breda, Simone G. J, van Agen, Ebienus, van Sanden, Suzy, Burzykowski, Tomasz, Kienhuis, Anne S, Kleinjans, Jos C. S, van Delft, Joost H. M

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Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance von Lin, J-W, Spaccapelo, R, Schwarzer, E, Sajid, M, Annoura, T, Deroost, K, Ravelli, RBG, Aime, E, Capuccini, B, Mommaas-Kienhuis, AM, O'Toole, T, Prins, F, Franke-Fayard, BMD, Ramesar, J, Chevalley-Maurel, S, Kroeze, H, Koster, AJ, Tanke, HJ, Crisanti, A, Langhorne, J, Arese, P, Van den Steen, PE, Janse, CJ, Khan, SM

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Classifying interprocess communication in process network representation of nested-loop programs von Turjan, Alexandru, Kienhuis, Bart, Deprettere, Ed

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A Process Splitting Transformation For Kahn Process Networks von Meijer, S., Kienhuis, B., Turjan, A., de Kock, E.

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