NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components von Doyle, Sarah L, Campbell, Matthew, Ozaki, Ema, Salomon, Robert G, Mori, Andres, Kenna, Paul F, Farrar, Gwyneth Jane, Kiang, Anna-Sophia, Humphries, Marian M, Lavelle, Ed C, O'Neill, Luke A J, Hollyfield, Joe G, Humphries, Peter

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Targeted suppression of claudin-5 decreases cerebral oedema and improves cognitive outcome following traumatic brain injury von Campbell, Matthew, Hanrahan, Finnian, Gobbo, Oliviero L., Kelly, Michael E., Kiang, Anna-Sophia, Humphries, Marian M., Nguyen, Anh T.H., Ozaki, Ema, Keaney, James, Blau, Christoph W., Kerskens, Christian M., Cahalan, Stephen D., Callanan, John J., Wallace, Eugene, Grant, Gerald A., Doherty, Colin P., Humphries, Peter

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Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm’s Canal Endothelia von Tam, Lawrence C. S., Reina-Torres, Ester, Sherwood, Joseph M., Cassidy, Paul S., Crosbie, Darragh E., Lütjen-Drecoll, Elke, Flügel-Koch, Cassandra, Perkumas, Kristin, Humphries, Marian M., Kiang, Anna-Sophia, O’Callaghan, Jeffrey, Callanan, John J., Read, A. Thomas, Ethier, C. Ross, O’Brien, Colm, Lawrence, Matthew, Campbell, Matthew, Stamer, W. Daniel, Overby, Darryl R., Humphries, Pete

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siRNA targeting Schlemm’s canal endothelial tight junctions enhances outflow facility and reduces IOP in a steroid-induced OHT rodent model von Cassidy, Paul S., Kelly, Ruth A., Reina-Torres, Ester, Sherwood, Joseph M., Humphries, Marian M., Kiang, Anna-Sophia, Farrar, G. Jane, O’Brien, Colm, Campbell, Matthew, Stamer, W. Daniel, Overby, Darryl R., Humphries, Pete, O’Callaghan, Jeffrey

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experimental platform for systemic drug delivery to the retina von Campbell, Matthew, Nguyen, Anh T.H, Kiang, Anna-Sophia, Tam, Lawrence C.S, Gobbo, Oliviero L, Kerskens, Christian, Dhubhghaill, Sorcha Ni, Humphries, Marian M, Farrar, G.-Jane, Kenna, Paul F, Humphries, Peter

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Advanced late-onset retinitis pigmentosa with dominant-acting D477G RPE65 mutation is responsive to oral synthetic retinoid therapy von Kenna, Paul F, Humphries, Marian M, Kiang, Anna-Sophia, Brabet, Philippe, Guillou, Laurent, Ozaki, Ema, Campbell, Matthew, Farrar, G Jane, Koenekoop, Robert, Humphries, Pete

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Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90) von Tam, Lawrence C.S., Kiang, Anna-Sophia, Campbell, Matthew, Keaney, James, Jane Farrar, G., Humphries, Marian M., Kenna, Paul F., Humphries, Pete

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RNAi-mediated reversible opening of the blood-brain barrier von Campbell, Matthew, Kiang, Anna-Sophia, Kenna, Paul F., Kerskens, Christian, Blau, Christoph, O'Dwyer, Laurence, Tivnan, Amanda, Kelly, Julie Anne, Brankin, Brenda, Farrar, Gwyneth-Jane, Humphries, Peter

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Systemic low‐molecular weight drug delivery to pre‐selected neuronal regions von Campbell, Matthew, Humphries, Marian M., Kiang, Anna‐Sophia, Nguyen, Anh T. H., Gobbo, Oliviero L., Tam, Lawrence C. S., Suzuki, Mayu, Hanrahan, Finnian, Ozaki, Ema, Farrar, G.‐Jane, Kenna, Paul F., Humphries, Peter

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Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma von O'Callaghan, Jeffrey, Crosbie, Darragh E, Cassidy, Paul S, Sherwood, Joseph M, Flügel-Koch, Cassandra, Lütjen-Drecoll, Elke, Humphries, Marian M, Reina-Torres, Ester, Wallace, Deborah, Kiang, Anna-Sophia, Campbell, Matthew, Stamer, W Daniel, Overby, Darryl R, O'Brien, Colm, Tam, Lawrence C S, Humphries, Peter

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Toward a Gene Therapy for Dominant Disease: Validation of an RNA Interference-Based Mutation-Independent Approach von Kiang, Anna-Sophia, Palfi, Arpad, Ader, Marius, Kenna, Paul F, Millington-Ward, Sophia, Clark, Gerry, Kennan, Avril, O'reilly, Mary, Tam, Lawrence C T, Aherne, Aileen, McNally, Niamh, Humphries, Pete, Farrar, G Jane

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C1q enhances cone photoreceptor survival in a mouse model of autosomal recessive retinitis pigmentosa von HUMPHRIES, Marian M, KENNA, Paul F, CAMPBELL, Matthew, TAM, Lawrence Cs, NGUYEN, Anh Th, JANE FARRAR, G, BOTTO, Marina, SOPHIA KIANG, Anna, HUMPHRIES, Peter

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RNAi-based suppression and replacement of rds-peripherin in retinal organotypic culture von Palfi, Arpad, Ader, Marius, Kiang, Anna-Sophia, Millington-Ward, Sophia, Clark, Gerry, O'Reilly, Mary, McMahon, Helena P., Kenna, Paul F., Humphries, Peter, Farrar, G. Jane

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Properties and Therapeutic Implications of an Enigmatic D477G RPE65 Variant Associated with Autosomal Dominant Retinitis Pigmentosa von Kiang, Anna-Sophia, Kenna, Paul F., Humphries, Marian M., Ozaki, Ema, Koenekoop, Robert K., Campbell, Matthew, Farrar, G. Jane, Humphries, Pete

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RNA Interference–Mediated Suppression and Replacement of Human Rhodopsin In Vivo von O’Reilly, Mary, Palfi, Arpad, Chadderton, Naomi, Millington-Ward, Sophia, Ader, Marius, Cronin, Thérèse, Tuohy, Thérèse, Auricchio, Alberto, Hildinger, Markus, Tivnan, Amanda, McNally, Niamh, Humphries, Marian M., Kiang, Anna-Sophia, Humphries, Pete, Kenna, Paul F., Farrar, G. Jane

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A novel mutation within the rhodopsin gene (Thr-94-Ile) causing autosomal dominant congenital stationary night blindness von al-Jandal, Najma, Farrar, G. Jane, Kiang, Anna-Sophia, Humphries, Marian M., Bannon, Noreen, Findlay, John B.C., Humphries, Peter, Kenna, Paul F.

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Therapeutic benefit derived from RNAi-mediated ablation of IMPDH1 transcripts in a murine model of autosomal dominant retinitis pigmentosa (RP10) von Tam, Lawrence C.S., Kiang, Anna-Sophia, Kennan, Avril, Kenna, Paul F., Chadderton, Naomi, Ader, Marius, Palfi, Arpad, Aherne, Aileen, Ayuso, Carmen, Campbell, Matthew, Reynolds, Alison, McKee, Alex, Humphries, Marian M., Farrar, G. Jane, Humphries, Pete

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Novel mutations in the TIGR gene in early and late onset open angle glaucoma von Mansergh, Fiona C., Kenna, Paul F., Ayuso, Carmen, Kiang, Anna-Sophia, Humphries, Peter, Farrar, G. Jane

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On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa von Aherne, Aileen, Kennan, Avril, Kenna, Paul F., McNally, Niamh, Lloyd, David G., Alberts, Ian L., Kiang, Anna-Sophia, Humphries, Marian M., Ayuso, Carmen, Engel, Paul C., Gu, Jing Jin, Mitchell, Beverly S., Farrar, G. Jane, Humphries, Pete

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Rnai of COL1A1 in mesenchymal progenitor cells von MILLINGTON-WARD, Sophia, MCMAHON, Helena P, ALLEN, Danny, TUOHY, Gearoid, KIANG, Anna-Sophia, PALFI, Arpad, KENNA, Paul F, HUMPHRIES, Peter, FARRAR, G. Jane

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