Lung cancer: New biological insights and recent therapeutic advances von Ramalingam, Suresh S., Owonikoko, Taofeek K., Khuri, Fadlo R.

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Tyrosine Phosphorylation of Mitochondrial Pyruvate Dehydrogenase Kinase 1 Is Important for Cancer Metabolism von Hitosugi, Taro, Fan, Jun, Chung, Tae-Wook, Lythgoe, Katherine, Wang, Xu, Xie, Jianxin, Ge, Qingyuan, Gu, Ting-Lei, Polakiewicz, Roberto D., Roesel, Johannes L., Chen, Georgia Z., Boggon, Titus J., Lonial, Sagar, Fu, Haian, Khuri, Fadlo R., Kang, Sumin, Chen, Jing

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Comparison of the toxicity profile of PD‐1 versus PD‐L1 inhibitors in non–small cell lung cancer: A systematic analysis of the literature von Pillai, Rathi N., Behera, Madhusmita, Owonikoko, Taofeek K., Kamphorst, Alice O., Pakkala, Suchita, Belani, Chandra P., Khuri, Fadlo R., Ahmed, Rafi, Ramalingam, Suresh S.

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Glutamate Dehydrogenase 1 Signals through Antioxidant Glutathione Peroxidase 1 to Regulate Redox Homeostasis and Tumor Growth von Jin, Lingtao, Li, Dan, Alesi, Gina N., Fan, Jun, Kang, Hee-Bum, Lu, Zhou, Boggon, Titus J., Jin, Peng, Yi, Hong, Wright, Elizabeth R., Duong, Duc, Seyfried, Nicholas T., Egnatchik, Robert, DeBerardinis, Ralph J., Magliocca, Kelly R., He, Chuan, Arellano, Martha L., Khoury, Hanna J., Shin, Dong M., Khuri, Fadlo R., Kang, Sumin

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The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer von Jin, Lingtao, Chun, Jaemoo, Pan, Chaoyun, Kumar, Avi, Zhang, Guojing, Ha, Youna, Li, Dan, Alesi, Gina N., Kang, Yibin, Zhou, Lu, Yu, Wen-Mei, Magliocca, Kelly R., Khuri, Fadlo R., Qu, Cheng-Kui, Metallo, Christian, Owonikoko, Taofeek K., Kang, Sumin

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HER2 mutations in lung adenocarcinomas: A report from the Lung Cancer Mutation Consortium von Pillai, Rathi N., Behera, Madhusmita, Berry, Lynne D., Rossi, Mike R., Kris, Mark G., Johnson, Bruce E., Bunn, Paul A., Ramalingam, Suresh S., Khuri, Fadlo R.

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Tyr Phosphorylation of PDP1 Toggles Recruitment between ACAT1 and SIRT3 to Regulate the Pyruvate Dehydrogenase Complex von Fan, Jun, Shan, Changliang, Kang, Hee-Bum, Elf, Shannon, Xie, Jianxin, Tucker, Meghan, Gu, Ting-Lei, Aguiar, Mike, Lonning, Scott, Chen, Huaibin, Mohammadi, Moosa, Britton, Laura-Mae P., Garcia, Benjamin A., Alečković, Maša, Kang, Yibin, Kaluz, Stefan, Devi, Narra, Van Meir, Erwin G., Hitosugi, Taro, Seo, Jae Ho, Lonial, Sagar, Gaddh, Manila, Arellano, Martha, Khoury, Hanna J., Khuri, Fadlo R., Boggon, Titus J., Kang, Sumin, Chen, Jing

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Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs von Kris, Mark G, Johnson, Bruce E, Berry, Lynne D, Kwiatkowski, David J, Iafrate, A. John, Wistuba, Ignacio I, Varella-Garcia, Marileila, Franklin, Wilbur A, Aronson, Samuel L, Su, Pei-Fang, Shyr, Yu, Camidge, D. Ross, Sequist, Lecia V, Glisson, Bonnie S, Khuri, Fadlo R, Garon, Edward B, Pao, William, Rudin, Charles, Schiller, Joan, Haura, Eric B, Socinski, Mark, Shirai, Keisuke, Chen, Heidi, Giaccone, Giuseppe, Ladanyi, Marc, Kugler, Kelly, Minna, John D, Bunn, Paul A

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Role of race in oncogenic driver prevalence and outcomes in lung adenocarcinoma: Results from the Lung Cancer Mutation Consortium von Steuer, Conor E., Behera, Madhusmita, Berry, Lynne, Kim, Sungjin, Rossi, Michael, Sica, Gabriel, Owonikoko, Taofeek K., Johnson, Bruce E., Kris, Mark G., Bunn, Paul A., Khuri, Fadlo R., Garon, Edward B., Ramalingam, Suresh S.

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Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling von Kang, Hee-Bum, Fan, Jun, Lin, Ruiting, Elf, Shannon, Ji, Quanjiang, Zhao, Liang, Jin, Lingtao, Seo, Jae Ho, Shan, Changliang, Arbiser, Jack L., Cohen, Cynthia, Brat, Daniel, Miziorko, Henry M., Kim, Eunhee, Abdel-Wahab, Omar, Merghoub, Taha, Fröhling, Stefan, Scholl, Claudia, Tamayo, Pablo, Barbie, David A., Zhou, Lu, Pollack, Brian P., Fisher, Kevin, Kudchadkar, Ragini R., Lawson, David H., Sica, Gabriel, Rossi, Michael, Lonial, Sagar, Khoury, Hanna J., Khuri, Fadlo R., Lee, Benjamin H., Boggon, Titus J., He, Chuan, Kang, Sumin, Chen, Jing

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Perspectives for Cancer Prevention With Natural Compounds von RUHUL AMIN, A. R. M, KUCUK, Omer, KHURI, Fadlo R, SHIN, Dong M

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The next generation of epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of lung cancer von Steuer, Conor E., Khuri, Fadlo R., Ramalingam, Suresh S.

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The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies von Li, Zenggang, Ivanov, Andrei A., Su, Rina, Gonzalez-Pecchi, Valentina, Qi, Qi, Liu, Songlin, Webber, Philip, McMillan, Elizabeth, Rusnak, Lauren, Pham, Cau, Chen, Xiaoqian, Mo, Xiulei, Revennaugh, Brian, Zhou, Wei, Marcus, Adam, Harati, Sahar, Chen, Xiang, Johns, Margaret A., White, Michael A., Moreno, Carlos S., Cooper, Lee A. D., Du, Yuhong, Khuri, Fadlo R., Fu, Haian

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Detection of Circulating Tumor Cells in Human Peripheral Blood Using Surface-Enhanced Raman Scattering Nanoparticles von XU WANG, XIMEI QIAN, BEITLER, Jonathan J, ZHUO GEORGIA CHEN, KHURI, Fadlo R, LEWIS, Melinda M, SHIN, Hyung Ju C, SHUMING NIE, SHIN, Dong M

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MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation von Jin, Lingtao, Chun, Jaemoo, Pan, Chaoyun, Li, Dan, Lin, Ruiting, Alesi, Gina N., Wang, Xu, Kang, Hee-Bum, Song, Lina, Wang, Dongsheng, Zhang, Guojing, Fan, Jun, Boggon, Titus J., Zhou, Lu, Kowalski, Jeanne, Qu, Cheng-Kui, Steuer, Conor E., Chen, Georgia Z., Saba, Nabil F., Boise, Lawrence H., Owonikoko, Taofeek K., Khuri, Fadlo R., Magliocca, Kelly R., Shin, Dong M., Lonial, Sagar, Kang, Sumin

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Lysine Acetylation Activates 6-Phosphogluconate Dehydrogenase to Promote Tumor Growth von Shan, Changliang, Elf, Shannon, Ji, Quanjiang, Kang, Hee-Bum, Zhou, Lu, Hitosugi, Taro, Jin, Lingtao, Lin, Ruiting, Zhang, Liang, Seo, Jae Ho, Xie, Jianxin, Tucker, Meghan, Gu, Ting-Lei, Sudderth, Jessica, Jiang, Lei, DeBerardinis, Ralph J., Wu, Shaoxiong, Li, Yuancheng, Mao, Hui, Chen, Peng R., Wang, Dongsheng, Chen, Georgia Zhuo, Lonial, Sagar, Arellano, Martha L., Khoury, Hanna J., Khuri, Fadlo R., Lee, Benjamin H., Brat, Daniel J., Ye, Keqiang, Boggon, Titus J., He, Chuan, Kang, Sumin, Fan, Jun, Chen, Jing

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Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation von Koo, Junghui, Wu, Xiaoyun, Mao, Zixu, Khuri, Fadlo R., Sun, Shi-Yong

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National Cancer Database Analysis of Proton Versus Photon Radiation Therapy in Non-Small Cell Lung Cancer von Higgins, Kristin A., O'Connell, Kelli, Liu, Yuan, Gillespie, Theresa W., McDonald, Mark W., Pillai, Rathi N., Patel, Kirtesh R., Patel, Pretesh R., Robinson, Clifford G., Simone, Charles B., Owonikoko, Taofeek K., Belani, Chandra P., Khuri, Fadlo R., Curran, Walter J., Ramalingam, Suresh S., Behera, Madhusmita

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Phosphoglycerate Mutase 1 Coordinates Glycolysis and Biosynthesis to Promote Tumor Growth von Hitosugi, Taro, Zhou, Lu, Elf, Shannon, Fan, Jun, Kang, Hee-Bum, Seo, Jae Ho, Shan, Changliang, Dai, Qing, Zhang, Liang, Xie, Jianxin, Gu, Ting-Lei, Jin, Peng, Alečković, Masa, LeRoy, Gary, Kang, Yibin, Sudderth, Jessica A., DeBerardinis, Ralph J., Luan, Chi-Hao, Chen, Georgia Z., Muller, Susan, Shin, Dong M., Owonikoko, Taofeek K., Lonial, Sagar, Arellano, Martha L., Khoury, Hanna J., Khuri, Fadlo R., Lee, Benjamin H., Ye, Keqiang, Boggon, Titus J., Kang, Sumin, He, Chuan, Chen, Jing

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Niclosamide overcomes acquired resistance to erlotinib through suppression of STAT3 in non-small cell lung cancer von Li, Rui, Hu, Zhongliang, Sun, Shi-Yong, Chen, Zhuo G, Owonikoko, Taofeek K, Sica, Gabriel L, Ramalingam, Suresh S, Curran, Walter J, Khuri, Fadlo R, Deng, Xingming

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