Association of CYP2C92 With Bosentan-Induced Liver Injury von Markova, S M, De Marco, T, Bendjilali, N, Kobashigawa, E A, Mefford, J, Sodhi, J, Le, H, Zhang, C, Halladay, J, Rettie, A E, Khojasteh, C, McGlothlin, D, Wu, A H B, Hsueh, W-C, Witte, J S, Schwartz, J B, Kroetz, D L

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Preclinical assessment of the absorption, distribution, metabolism and excretion of GDC-0449 (2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide), an orally b... von Wong, H., Chen, J.Z., Chou, B., Halladay, J.S., Kenny, J.R., La, H., Marsters, J.C., Plise, E., Rudewicz, P.J., Robarge, K., Shin, Y., Wong, S., Zhang, C., Khojasteh, S.C.

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Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543 von Khojasteh-Bakht, S. C., Rossulek, M. I., Fouda, H. G., Prakash, C.

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Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug von Khojasteh, S. C., Leipold, D. D., Lai, F., La, H., Baumgardner, M. J., Desino, K. E., Gudmundsson, O. S., Bloedow, D. C., Bodary, S. C., Reynolds, M. E., Gadek, T. R., Kenkare-Mitra, S.

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Biotransformation Reactions of Five-Membered Aromatic Heterocyclic Rings von Dalvie, Deepak K, Kalgutkar, Amit S, Khojasteh-Bakht, S. Cyrus, Obach, R. Scott, O'Donnell, John P

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Glutathione S-Transferase Catalyzes the Isomerization of (R)-2-Hydroxymenthofuran to Mintlactones von Khojasteh-Bakht, Siamak C., Nelson, Sidney D., Atkins, William M.

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For a series of methylindole analogs, reactive metabolite formation is a poor predictor of intrinsic cytotoxicity in human hepatocytes von Zhang, Chenghong, Ma, Shuguang, Delarosa, Erlie Marie, Tay, Suzanne, Sodhi, Jasleen, Musinipally, Vivek, Chang, Patricia, Pai, Rama, Halladay, Jason S., Misner, Dinah, Kenny, Jane R., Hop, Cornelis E. C. A., Khojasteh, S. Cyrus

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Malignant lymphoreticular lesions in patients with immune disorders resembling acquired immunodeficiency syndrome (AIDS): review of 80 cases von Khojasteh, A, Reynolds, R D, Khojasteh, C A

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Preclinical absorption, distributior metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug von Khojasteh, S C, Leipold, D D, Lai, F, La, H, Baumgardner, MJ, Desino, KE, Gudmundsson, O S, Bloedow, D C, Bodary, S C, Reynolds, ME, Gadek, T R, Kenkare-Mitra, S

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Automated online liquid chromatographic/mass spectrometric metabolic study for prodrug stability von Lai, Fran, Khojasteh-Bakht, Siamak Cyrus

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Drug Concentration Asymmetry in Tissues and Plasma for Small Molecule-Related Therapeutic Modalities von Zhang, Donglu, Hop, Cornelis E C A, Patilea-Vrana, Gabriela, Gampa, Gautham, Seneviratne, Herana Kamal, Unadkat, Jashvant D, Kenny, Jane R, Nagapudi, Karthik, Di, Li, Zhou, Lian, Zak, Mark, Wright, Matthew R, Bumpus, Namandjé N, Zang, Richard, Liu, Xingrong, Lai, Yurong, Khojasteh, S Cyrus

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Cognitive training and remediation interventions for substance use disorders: a Delphi consensus study von Verdejo‐Garcia, Antonio, Rezapour, Tara, Giddens, Emily, Khojasteh Zonoozi, Arash, Rafei, Parnian, Berry, Jamie, Caracuel, Alfonso, Copersino, Marc L., Field, Matt, Garland, Eric L., Lorenzetti, Valentina, Malloy‐Diniz, Leandro, Manning, Victoria, Marceau, Ely M., Pennington, David L., Strickland, Justin C., Wiers, Reinout, Fairhead, Rahia, Anderson, Alexandra, Bell, Morris, Boendermaker, Wouter J., Brooks, Samantha, Bruno, Raimondo, Campanella, Salvatore, Cousijn, Janna, Cox, W. Miles, Dean, Andrew C., Ersche, Karen D., Franken, Ingmar, Froeliger, Brett, Gamito, Pedro, Gladwin, Thomas E., Goncalves, Priscila D., Houben, Katrijn, Jacobus, Joanna, Jones, Andrew, Kaag, Anne M., Lindenmeyer, Johannes, McGrath, Elly, Nardo, Talia, Oliveira, Jorge, Pennington, Charlotte R., Perrykkad, Kelsey, Piercy, Hugh, Rupp, Claudia I., Schulte, Mieke H. J., Squeglia, Lindsay M., Staiger, Petra, Stein, Dan J., Stein, Jeff, Stein, Maria, Stoops, William W., Sweeney, Mary, Witkiewitz, Katie, Woods, Steven P., Yi, Richard, Zhao, Min, Ekhtiari, Hamed

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Intratumoral Payload Concentration Correlates with the Activity of Antibody-Drug Conjugates von Zhang, Donglu, Yu, Shang-Fan, Khojasteh, S Cyrus, Ma, Yong, Pillow, Thomas H, Sadowsky, Jack D, Su, Dian, Kozak, Katherine R, Xu, Keyang, Polson, Andrew G, Dragovich, Peter S, Hop, Cornelis E C A

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Public awareness of cardiopulmonary resuscitation and cardiac arrest in association with Christian Eriksen von Ferrell, M.C., Khojasteh, J., Vassar, M.

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Exposure-Efficacy Analysis of Antibody-Drug Conjugates Delivering an Excessive Level of Payload to Tissues von Zhang, Donglu, Dragovich, Peter S., Yu, Shang-Fan, Ma, Yong, Pillow, Thomas H., Sadowsky, Jack D., Su, Dian, Wang, Wei, Polson, Andrew, Khojasteh, S. Cyrus, Hop, Cornelis E.C.A.

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Catalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody–Drug Conjugates von Zhang, Donglu, Fourie-O’Donohue, Aimee, Dragovich, Peter S., Pillow, Thomas H., Sadowsky, Jack D., Kozak, Katherine R., Cass, Robert T., Liu, Liling, Deng, Yuzhong, Liu, Yichin, Hop, Cornelis E.C.A., Khojasteh, S. Cyrus

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A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance von Schadt, Simone, Bister, Bojan, Chowdhury, Swapan K., Funk, Christoph, Hop, Cornelis E.C.A., Humphreys, W. Griffith, Igarashi, Fumihiko, James, Alexander D., Kagan, Mark, Khojasteh, S. Cyrus, Nedderman, Angus N.R., Prakash, Chandra, Runge, Frank, Scheible, Holger, Spracklin, Douglas K., Swart, Piet, Tse, Susanna, Yuan, Josh, Obach, R. Scott

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A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834 von Sodhi, Jasleen K, Wong, Susan, Kirkpatrick, Donald S, Liu, Lichuan, Khojasteh, S. Cyrus, Hop, Cornelis E. C. A, Barr, John T, Jones, Jeffrey P, Halladay, Jason S

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Intestinal Excretion, Intestinal Recirculation, and Renal Tubule Reabsorption Are Underappreciated Mechanisms That Drive the Distribution and Pharmacokinetic Behavior of Small Mole... von Zhang, Donglu, Wei, Cong, Hop, Cornelis E. C. A., Wright, Matthew R., Hu, Ming, Lai, Yurong, Khojasteh, S. Cyrus, Humphreys, W. Griff

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Effect of Pupil Size on Fixed-Luminance Flicker Full-Field Electroretinogram Magnitude von Mobasserian, Azadeh, Zaidi, Moosa, Halim, Sohail, Hwang, Jaclyn Joyce, Regenold, Jonathan, Akhavanrezayat, Amir, Karaca, Irmak, Khojasteh Jafari, Hassan, Yavari, Negin, Matsumiya, Wataru, Yasar, Cigdem, Than, Ngoc Tuong Trong, Uludag, Gunay, Do, Diana, Ghoraba, Hashem, Nguyen, Quan Dong

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